JPS5581863A - Novel aminopyrimidine type carboanilide compounds and their manufacture - Google Patents

Novel aminopyrimidine type carboanilide compounds and their manufacture

Info

Publication number
JPS5581863A
JPS5581863A JP15827579A JP15827579A JPS5581863A JP S5581863 A JPS5581863 A JP S5581863A JP 15827579 A JP15827579 A JP 15827579A JP 15827579 A JP15827579 A JP 15827579A JP S5581863 A JPS5581863 A JP S5581863A
Authority
JP
Japan
Prior art keywords
compounds
carboanilide
manufacture
type
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15827579A
Other languages
English (en)
Other versions
JPH0457675B2 (ja
Inventor
Kamupe Kurausuudeiiteru
Gurantsuaa Erunoruto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of JPS5581863A publication Critical patent/JPS5581863A/ja
Publication of JPH0457675B2 publication Critical patent/JPH0457675B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
JP15827579A 1978-12-09 1979-12-07 Novel aminopyrimidine type carboanilide compounds and their manufacture Granted JPS5581863A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782853220 DE2853220A1 (de) 1978-12-09 1978-12-09 Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung

Publications (2)

Publication Number Publication Date
JPS5581863A true JPS5581863A (en) 1980-06-20
JPH0457675B2 JPH0457675B2 (ja) 1992-09-14

Family

ID=6056720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15827579A Granted JPS5581863A (en) 1978-12-09 1979-12-07 Novel aminopyrimidine type carboanilide compounds and their manufacture

Country Status (9)

Country Link
US (1) US4285946A (ja)
EP (1) EP0012361B1 (ja)
JP (1) JPS5581863A (ja)
AT (1) ATE1288T1 (ja)
AU (1) AU529426B2 (ja)
CA (1) CA1136623A (ja)
DE (2) DE2853220A1 (ja)
ES (3) ES486536A0 (ja)
ZA (1) ZA796651B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641120A (ja) * 1992-02-22 1994-02-15 Hoechst Ag ４−アミノ−２−ウレイドピリミジン−５−カルボキサミド、その製造法、これらの化合物を含有する薬剤およびその使用
US20110210503A1 (en) * 2008-09-24 2011-09-01 Universal Entertainment Corporation Paper sheet processing device
JP2015500842A (ja) * 2011-12-21 2015-01-08 ビオタ ヨーロッパ リミテッドＢｉｏｔａ Ｅｕｒｏｐｅ Ｌｔｄ 複素環式ウレア化合物

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4436911A (en) * 1981-05-12 1984-03-13 William H. Rorer, Inc. Heterocyclic amidinoureas
JPS58501468A (ja) * 1981-08-24 1983-09-01 ロウラ−　インタ−ナシヨナル　（オ−バ−シ−ズ）　インコ−ポレ−テツド 複素環アミジノ置換尿素およびそれらの薬剤利用
DE3522940A1 (de) * 1985-06-27 1987-01-08 Hoechst Ag 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln
DK0557877T3 (da) * 1992-02-22 1998-04-27 Hoechst Ag Opløselige salte af 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-eN-methyl-N-(3-trifluormethyl-phenyl)-amide,fremgangsmådetil deres fremstilling, deres anvendelse som lægemidler og udgangsprodukter
DE19625088A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19625089A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP1223170B1 (en) 1999-10-12 2005-12-28 Takeda Pharmaceutical Company Limited Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof
US7176310B1 (en) * 2002-04-09 2007-02-13 Ucb Sa Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents
CA2612227C (en) * 2005-06-14 2014-04-22 Taigen Biotechnology Co., Ltd. Pyrimidine compounds
US8193206B2 (en) * 2005-06-14 2012-06-05 Taigen Biotechnology Co., Ltd. Pyrimidine compounds
CA2718528C (en) * 2008-03-18 2016-10-25 Merck Sharp & Dohme Corp. Substituted 4-hydroxypyrimidine-5-carboxamides
WO2016161268A1 (en) 2015-04-01 2016-10-06 Enanta Pharmaceuticals, Inc. Hepatitis b antviral agents
US10738035B2 (en) * 2015-05-13 2020-08-11 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
WO2017011552A1 (en) 2015-07-13 2017-01-19 Enanta Pharmaceuticals, Inc. Hepatitis b antiviral agents
US10301255B2 (en) 2015-07-22 2019-05-28 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US10280175B2 (en) 2016-02-02 2019-05-07 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US10179792B2 (en) 2016-03-07 2019-01-15 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US10189846B2 (en) 2016-06-10 2019-01-29 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
BR112020004112A2 (pt) 2017-08-28 2020-09-24 Enanta Pharmaceuticals, Inc. agentes antiviras da hepatite b
TW201936192A (zh) 2017-12-06 2019-09-16 美商因那塔製藥公司 B 型肝炎抗病毒試劑
US10428070B2 (en) 2017-12-06 2019-10-01 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US11058678B2 (en) 2018-01-22 2021-07-13 Enanta Pharmaceuticals, Inc. Substituted heterocycles as antiviral agents
US10729688B2 (en) 2018-03-29 2020-08-04 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
UY38383A (es) 2018-09-21 2020-04-30 Enanta Pharm Inc Heterociclos funcionalizados como agentes antivirales
EP3883570A4 (en) 2018-11-21 2022-07-13 Enanta Pharmaceuticals, Inc. FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS
US11236111B2 (en) 2019-06-03 2022-02-01 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US11472808B2 (en) 2019-06-04 2022-10-18 Enanta Pharmaceuticals, Inc. Substituted pyrrolo[1,2-c]pyrimidines as hepatitis B antiviral agents
US11760755B2 (en) 2019-06-04 2023-09-19 Enanta Pharmaceuticals, Inc. Hepatitis B antiviral agents
US11738019B2 (en) 2019-07-11 2023-08-29 Enanta Pharmaceuticals, Inc. Substituted heterocycles as antiviral agents
WO2021055425A2 (en) 2019-09-17 2021-03-25 Enanta Pharmaceuticals, Inc. Functionalized heterocycles as antiviral agents
US11802125B2 (en) 2020-03-16 2023-10-31 Enanta Pharmaceuticals, Inc. Functionalized heterocyclic compounds as antiviral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1031265A (en) * 1963-11-12 1966-06-02 Geigy Co Ltd Tri-tertiary aminopyrimidines and their production
US3479357A (en) * 1967-10-20 1969-11-18 Searle & Co (6 - phenylpyrimidine)mono/bis(1h - 1,2,3-triazole- 4,5-dicarboxylic acid) lower alkyl esters

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641120A (ja) * 1992-02-22 1994-02-15 Hoechst Ag ４−アミノ−２−ウレイドピリミジン−５−カルボキサミド、その製造法、これらの化合物を含有する薬剤およびその使用
US20110210503A1 (en) * 2008-09-24 2011-09-01 Universal Entertainment Corporation Paper sheet processing device
US8313100B2 (en) 2008-09-24 2012-11-20 Universal Entertainment Corporation Paper sheet processing apparatus with redetection process and method of conveying paper sheet
JP2015500842A (ja) * 2011-12-21 2015-01-08 ビオタ ヨーロッパ リミテッドＢｉｏｔａ Ｅｕｒｏｐｅ Ｌｔｄ 複素環式ウレア化合物

Also Published As

Publication number Publication date
ES8101069A1 (es) 1980-12-01
ZA796651B (en) 1981-05-27
AU529426B2 (en) 1983-06-09
ES8102121A1 (es) 1980-12-16
ES8101068A1 (es) 1980-12-01
EP0012361A1 (de) 1980-06-25
AU5357179A (en) 1980-06-12
EP0012361B1 (de) 1982-06-30
ATE1288T1 (de) 1982-07-15
CA1136623A (en) 1982-11-30
DE2853220A1 (de) 1980-07-03
ES491225A0 (es) 1980-12-01
ES491224A0 (es) 1980-12-01
JPH0457675B2 (ja) 1992-09-14
US4285946A (en) 1981-08-25
ES486536A0 (es) 1980-12-16
DE2963278D1 (en) 1982-08-19

Similar Documents

Publication Publication Date Title
JPS5581863A (en) Novel aminopyrimidine type carboanilide compounds and their manufacture
IL76457A (en) Tetralin derivatives,their preparation and pharmaceutical compositions containing them
ES8200665A1 (es) Procedimiento para la preparacion de sulfonilureas
ES8102125A1 (es) Procedimiento para la preparacion de derivados de pirimido-(6,1-a)-isoquinolein-4-onas
ES8402261A1 (es) Procedimiento para la obtencion de nuevos derivados de omega-ciano-1,omega difenil-aza-alcano.
ES8102561A1 (es) Procedimiento de preparacion de los aril-1 arilsulfonil-4 a amino-propoxi-3 1h pirazoles
DE3378580D1 (en) Imidazolylphenyl-tetrahydropyridazines, process for their preparation and pharmaceutical compositions containing them
DE3170937D1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
ES8200680A1 (es) Un procedimiento para la preparacion de fenil-quinolicidinas
ES480111A1 (es) Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina.
DE3062340D1 (en) 1-n-alkylsisomicin derivatives, process for their preparation and their use as medicines
ES8401946A1 (es) Procedimiento para la preparacion de sulfonilureas.
ZA874470B (en) New tetrahydrobenzothiazoles,and the preparation and use thereof
DE2963792D1 (en) Indanyloxamic derivatives, their preparation and pharmaceutical compositions containing them