JPS5555196A - Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation - Google Patents

Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation

Info

Publication number
JPS5555196A
JPS5555196A JP12855778A JP12855778A JPS5555196A JP S5555196 A JPS5555196 A JP S5555196A JP 12855778 A JP12855778 A JP 12855778A JP 12855778 A JP12855778 A JP 12855778A JP S5555196 A JPS5555196 A JP S5555196A
Authority
JP
Japan
Prior art keywords
hexahydronaphtho
imidazo
thiazole
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12855778A
Other languages
Japanese (ja)
Inventor
Yasukata Shikayama
Takeshi Hara
Yoji Suzuki
Masahiko Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP12855778A priority Critical patent/JPS5555196A/en
Priority to DE19792950518 priority patent/DE2950518A1/en
Priority to PCT/JP1979/000122 priority patent/WO1979001080A1/en
Priority to GB8001200A priority patent/GB2036026A/en
Priority to EP79900559A priority patent/EP0019634A1/en
Publication of JPS5555196A publication Critical patent/JPS5555196A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Hexahydronaphtho[1',2':4,5]imidazo[2,1-b]thiazole of formula I (the B and the C rings are in cis configuration), and its acid addition salt.
EXAMPLE: cis-5,6,6a,8,9,11a-Hexahydronaphtho[1',2':4,5]imidazo[2,1-b]thiazole.
USE: Immunosuppressive agents and anthelmintics for animal. Effective to autoimmne diseases such as cancer, rheumatic arthritis, etc.
PROCESS: The compound I is prepared by reacting tetrahydronaphtho[1,2-d]imidazolin-2-thione of formula II with a compound of formula III(X, Y are halogen, arylsulfonyloxy, etc.), and if necessary, treating the product with an acid.
COPYRIGHT: (C)1980,JPO&Japio
JP12855778A 1978-05-17 1978-10-20 Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation Pending JPS5555196A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP12855778A JPS5555196A (en) 1978-10-20 1978-10-20 Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation
DE19792950518 DE2950518A1 (en) 1978-05-17 1979-05-14 HEXAHYDRONAPHTOIMIDAZOTHIAZOLES AND PROCESS FOR PREPARING SAME
PCT/JP1979/000122 WO1979001080A1 (en) 1978-05-17 1979-05-14 Hexahydronaphtoimidazothiazoles and process for preparing same
GB8001200A GB2036026A (en) 1978-05-17 1979-05-14 Hexahydronaphthoimidazothiazoles and process for preparing same
EP79900559A EP0019634A1 (en) 1978-05-17 1979-12-17 Hexahydronaphtoimidazothiazoles and process for preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12855778A JPS5555196A (en) 1978-10-20 1978-10-20 Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation

Publications (1)

Publication Number Publication Date
JPS5555196A true JPS5555196A (en) 1980-04-22

Family

ID=14987700

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12855778A Pending JPS5555196A (en) 1978-05-17 1978-10-20 Hexahydronaphtho(1',2':4,5)imidazo(2,1-b)thiazole and its preparation

Country Status (1)

Country Link
JP (1) JPS5555196A (en)

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