JPS5549369A - Antitumorigenic substance - Google Patents
Antitumorigenic substanceInfo
- Publication number
- JPS5549369A JPS5549369A JP12155178A JP12155178A JPS5549369A JP S5549369 A JPS5549369 A JP S5549369A JP 12155178 A JP12155178 A JP 12155178A JP 12155178 A JP12155178 A JP 12155178A JP S5549369 A JPS5549369 A JP S5549369A
- Authority
- JP
- Japan
- Prior art keywords
- compounds
- product
- solvent
- formula
- methanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Compounds of formula I, II, and III.
USE: Carcinostatics.
PREPARATION: Dried joe-pye weed, Eupatorium chinense var. simplicifolium, is extracted with an organic solvent as methanol at room temperature or under heating and the extract is concentrated under reduced pressure to obtain the primary extracted product. Said product is subjected to solvent distribution using solvent systems as chlorform-water, then aqueous methanol containing 10% petroleum ether to separate hydrophilic and hydrophobic impurities, thus giving the secondary extracted product. The product is dissolved in an appropriate solvent as chloroform and the solution is passed over a column filled with usually silica gel or alumina as an adsorbent, whereby the extract components are adsorbed on the adsorbent. Then, the adsorbed compounds are eluted with an appropriate solvent as a chloroform-methanol 9:1 mixture to obtains fractions containing compounds of formula IW III. They are purified and isolated by changing solvents to give compounds of formula IWIII respectively.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12155178A JPS5549369A (en) | 1978-10-04 | 1978-10-04 | Antitumorigenic substance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12155178A JPS5549369A (en) | 1978-10-04 | 1978-10-04 | Antitumorigenic substance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5549369A true JPS5549369A (en) | 1980-04-09 |
Family
ID=14814037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12155178A Pending JPS5549369A (en) | 1978-10-04 | 1978-10-04 | Antitumorigenic substance |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5549369A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056142C (en) * | 1993-01-04 | 2000-09-06 | 昆明医学院第一附属医院 | Anti-cancer medicine inula helianthus-aquatica lactone |
| US20150157675A1 (en) * | 2012-04-02 | 2015-06-11 | Sung Kyun Biotech Co., Ltd. | Composition comprising eupatorium spp. extract as active ingredient for preventing and treating obesity and metabolic bone disease |
| CN110393712A (en) * | 2019-03-05 | 2019-11-01 | 浙江中医药大学 | Anti-tumor effective component extracted from agrimony and its preparation method and application |
-
1978
- 1978-10-04 JP JP12155178A patent/JPS5549369A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1056142C (en) * | 1993-01-04 | 2000-09-06 | 昆明医学院第一附属医院 | Anti-cancer medicine inula helianthus-aquatica lactone |
| US20150157675A1 (en) * | 2012-04-02 | 2015-06-11 | Sung Kyun Biotech Co., Ltd. | Composition comprising eupatorium spp. extract as active ingredient for preventing and treating obesity and metabolic bone disease |
| CN110393712A (en) * | 2019-03-05 | 2019-11-01 | 浙江中医药大学 | Anti-tumor effective component extracted from agrimony and its preparation method and application |
| CN110393712B (en) * | 2019-03-05 | 2023-04-21 | 浙江中医药大学 | Anti-tumor effective part extracted from cannabis sativa leaf herba lycopi and preparation method and application thereof |
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