JPS5547653A - Novel vitamin d derivative and its preparation - Google Patents
Novel vitamin d derivative and its preparationInfo
- Publication number
- JPS5547653A JPS5547653A JP11991578A JP11991578A JPS5547653A JP S5547653 A JPS5547653 A JP S5547653A JP 11991578 A JP11991578 A JP 11991578A JP 11991578 A JP11991578 A JP 11991578A JP S5547653 A JPS5547653 A JP S5547653A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- derivative
- preparation
- vitamin
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003710 vitamin D derivatives Chemical class 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000003127 radioimmunoassay Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229940014800 succinic anhydride Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11991578A JPS5547653A (en) | 1978-09-30 | 1978-09-30 | Novel vitamin d derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11991578A JPS5547653A (en) | 1978-09-30 | 1978-09-30 | Novel vitamin d derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5547653A true JPS5547653A (en) | 1980-04-04 |
| JPS6148497B2 JPS6148497B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-10-24 |
Family
ID=14773331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11991578A Granted JPS5547653A (en) | 1978-09-30 | 1978-09-30 | Novel vitamin d derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5547653A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5892656A (ja) * | 1981-11-30 | 1983-06-02 | Teijin Ltd | 新規ビタミンｄ↓３誘導体およびその製造法 |
| JPS59148775A (ja) * | 1983-02-14 | 1984-08-25 | Teijin Ltd | ２５―ヒドロキシビタミンｄ３―２６，２３―ラクトン誘導体 |
| JPS60130581A (ja) * | 1983-12-19 | 1985-07-12 | Teijin Ltd | １α，２５−ジヒドロキシビタミンＤ↓３−２６，２３−ラクトンの製造法 |
| US5075465A (en) * | 1987-10-14 | 1991-12-24 | Toyo Jozo Kabushiki Kaisha | 25-hydroxy vitamin d3 derivatives, process for their production, and assay method using the same |
| US5117018A (en) * | 1988-10-05 | 1992-05-26 | Toyo Jozo Kabushiki Kaisha | 1α (or 24R), 25-dihydroxy vitamin D3 derivatives |
| US5202266A (en) * | 1987-10-14 | 1993-04-13 | Asahi Kasei Kogyo Kabushiki Kaisha | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same |
| US5214170A (en) * | 1988-10-05 | 1993-05-25 | Toyo Jozo Kabushiki Kaisha | Radioisotope iodine-labeled 1α (or 24R), 25-dihydroxy vitamin D3 |
-
1978
- 1978-09-30 JP JP11991578A patent/JPS5547653A/ja active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5892656A (ja) * | 1981-11-30 | 1983-06-02 | Teijin Ltd | 新規ビタミンｄ↓３誘導体およびその製造法 |
| JPS59148775A (ja) * | 1983-02-14 | 1984-08-25 | Teijin Ltd | ２５―ヒドロキシビタミンｄ３―２６，２３―ラクトン誘導体 |
| JPS60130581A (ja) * | 1983-12-19 | 1985-07-12 | Teijin Ltd | １α，２５−ジヒドロキシビタミンＤ↓３−２６，２３−ラクトンの製造法 |
| US5075465A (en) * | 1987-10-14 | 1991-12-24 | Toyo Jozo Kabushiki Kaisha | 25-hydroxy vitamin d3 derivatives, process for their production, and assay method using the same |
| US5202266A (en) * | 1987-10-14 | 1993-04-13 | Asahi Kasei Kogyo Kabushiki Kaisha | 25-hydroxy vitamin D3 derivatives, process for their production, and assay method using the same |
| US5117018A (en) * | 1988-10-05 | 1992-05-26 | Toyo Jozo Kabushiki Kaisha | 1α (or 24R), 25-dihydroxy vitamin D3 derivatives |
| US5214170A (en) * | 1988-10-05 | 1993-05-25 | Toyo Jozo Kabushiki Kaisha | Radioisotope iodine-labeled 1α (or 24R), 25-dihydroxy vitamin D3 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6148497B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-10-24 |
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