JPS55337A - Anti-fungus agent - Google Patents
Anti-fungus agentInfo
- Publication number
- JPS55337A JPS55337A JP7363678A JP7363678A JPS55337A JP S55337 A JPS55337 A JP S55337A JP 7363678 A JP7363678 A JP 7363678A JP 7363678 A JP7363678 A JP 7363678A JP S55337 A JPS55337 A JP S55337A
- Authority
- JP
- Japan
- Prior art keywords
- holotoxin
- formula
- hydrolyzed
- buffer solution
- compound shown
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by the formula I (R is H or β-D-glycopyranosyl).
USE: An anti-fungus agent. A strong antibacterial action against pathogenic fungi.
PROCESS: A holotoxin B shown by the formula II is hydrolyzed in the presence of an enzyme in an acidic buffer solution to prepare the desired compound shown by the formula I. For example, a raw material, holotoxin B, is obtained by extracting holotoxin from trepangs, followed by treating it by column chromatography. In case of a compound shown by the formula I in which R is H (called HPH-4), the holotoxin B is resolved into a buffer solution, e.g., a sodium acetate-acetic acid mixture and hydrolyzed in the presence of a glucosidase, e.g., hesperidinase, at 35W40°C for oneWtwo days under stirring. In the case of β-D-glucopyranosyl group of R (called HPH-5) the holotoxin B is resolved into an aqueous dilute acetic acid solution or an acidic buffer solution and hydrolyzed in the presence of a glucosidase, e.g., almond emulsin, at 35W40°C for 1W3 days under stirring.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7363678A JPS55337A (en) | 1978-06-17 | 1978-06-17 | Anti-fungus agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7363678A JPS55337A (en) | 1978-06-17 | 1978-06-17 | Anti-fungus agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55337A true JPS55337A (en) | 1980-01-05 |
| JPS63440B2 JPS63440B2 (en) | 1988-01-07 |
Family
ID=13523982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7363678A Granted JPS55337A (en) | 1978-06-17 | 1978-06-17 | Anti-fungus agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55337A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100593560B1 (en) | 2005-01-27 | 2006-06-30 | 대한민국 | New compound separated from fruit of japanese styrax, separating method for new compound, antifungal material containing thereof |
| JP2009011619A (en) * | 2007-07-06 | 2009-01-22 | Dainippon Jochugiku Co Ltd | Gel-like aromatic and its use method |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6482428A (en) * | 1987-09-24 | 1989-03-28 | Anritsu Corp | Electromagnet structure for electromagnetic relay |
-
1978
- 1978-06-17 JP JP7363678A patent/JPS55337A/en active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100593560B1 (en) | 2005-01-27 | 2006-06-30 | 대한민국 | New compound separated from fruit of japanese styrax, separating method for new compound, antifungal material containing thereof |
| JP2009011619A (en) * | 2007-07-06 | 2009-01-22 | Dainippon Jochugiku Co Ltd | Gel-like aromatic and its use method |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63440B2 (en) | 1988-01-07 |
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