JPS5520713A - Drug for external use for accelerating heal of skin injury - Google Patents

Drug for external use for accelerating heal of skin injury

Info

Publication number
JPS5520713A
JPS5520713A JP9317178A JP9317178A JPS5520713A JP S5520713 A JPS5520713 A JP S5520713A JP 9317178 A JP9317178 A JP 9317178A JP 9317178 A JP9317178 A JP 9317178A JP S5520713 A JPS5520713 A JP S5520713A
Authority
JP
Japan
Prior art keywords
formula
compound
heal
accelerating
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9317178A
Other languages
Japanese (ja)
Other versions
JPS6410495B2 (en
Inventor
Shizumasa Kijima
Isao Yamatsu
Yuichi Inai
Tetsuya Tajima
Yoshinori Kato
Keiichi Nomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP9317178A priority Critical patent/JPS5520713A/en
Publication of JPS5520713A publication Critical patent/JPS5520713A/en
Publication of JPS6410495B2 publication Critical patent/JPS6410495B2/ja
Granted legal-status Critical Current

Links

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: To provide the title drug having low toxicity and no side-effects, and effective to incision, scald, eczema, atopic dermatitis, cutaneous ulcer, etc., by using specific prenyl ketone compounds (some of which are novel) as effective components.
CONSTITUTION: Compound of formula I [the sign of formula V represents a saturated or unsaturated bond; R1 is lower alkyl; R2 is prenyl group of formula VI (l, m and n are O or 1, with the proviso that 1+m+n≥2; a-f are H, a-b, c-d and e-f form bonds)] is added as an effective component to cream for external application, ointment, etc. for accelerating the heal of skin injury. The compound of formula I is obtained, e.g., by the alkali treatment of a compound of formula IV obtained by the reaction of a compound of formula II (X is halogen) with a compound of formula III in the presence of a condensing agent.
COPYRIGHT: (C)1980,JPO&Japio
JP9317178A 1978-08-01 1978-08-01 Drug for external use for accelerating heal of skin injury Granted JPS5520713A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9317178A JPS5520713A (en) 1978-08-01 1978-08-01 Drug for external use for accelerating heal of skin injury

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9317178A JPS5520713A (en) 1978-08-01 1978-08-01 Drug for external use for accelerating heal of skin injury

Publications (2)

Publication Number Publication Date
JPS5520713A true JPS5520713A (en) 1980-02-14
JPS6410495B2 JPS6410495B2 (en) 1989-02-22

Family

ID=14075116

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9317178A Granted JPS5520713A (en) 1978-08-01 1978-08-01 Drug for external use for accelerating heal of skin injury

Country Status (1)

Country Link
JP (1) JPS5520713A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07309710A (en) * 1994-05-20 1995-11-28 Eisai Co Ltd External base
JP2008214195A (en) * 2007-02-28 2008-09-18 Nagasaki Univ Skin burn medicine and skin regeneration promoter
WO2013052148A1 (en) * 2011-10-04 2013-04-11 Coyote Pharmaceuticals, Inc. Geranylgeranylacetone derivatives
US9045403B2 (en) 2012-02-29 2015-06-02 Coyote Pharmaceuticals, Inc. Geranyl geranyl acetone (GGA) derivatives and compositions thereof
US9119808B1 (en) 2012-10-08 2015-09-01 Coyote Pharmaceuticals, Inc. Treating neurodegenerative diseases with GGA or a derivative thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07309710A (en) * 1994-05-20 1995-11-28 Eisai Co Ltd External base
JP2008214195A (en) * 2007-02-28 2008-09-18 Nagasaki Univ Skin burn medicine and skin regeneration promoter
WO2013052148A1 (en) * 2011-10-04 2013-04-11 Coyote Pharmaceuticals, Inc. Geranylgeranylacetone derivatives
JP2014530810A (en) * 2011-10-04 2014-11-20 コヨーテ ファーマシューティカルズ インコーポレイテッド Geranylgeranylacetone derivatives
US9045403B2 (en) 2012-02-29 2015-06-02 Coyote Pharmaceuticals, Inc. Geranyl geranyl acetone (GGA) derivatives and compositions thereof
US9119808B1 (en) 2012-10-08 2015-09-01 Coyote Pharmaceuticals, Inc. Treating neurodegenerative diseases with GGA or a derivative thereof

Also Published As

Publication number Publication date
JPS6410495B2 (en) 1989-02-22

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