JPS5520713A - Drug for external use for accelerating heal of skin injury - Google Patents
Drug for external use for accelerating heal of skin injuryInfo
- Publication number
- JPS5520713A JPS5520713A JP9317178A JP9317178A JPS5520713A JP S5520713 A JPS5520713 A JP S5520713A JP 9317178 A JP9317178 A JP 9317178A JP 9317178 A JP9317178 A JP 9317178A JP S5520713 A JPS5520713 A JP S5520713A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- heal
- accelerating
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PURPOSE: To provide the title drug having low toxicity and no side-effects, and effective to incision, scald, eczema, atopic dermatitis, cutaneous ulcer, etc., by using specific prenyl ketone compounds (some of which are novel) as effective components.
CONSTITUTION: Compound of formula I [the sign of formula V represents a saturated or unsaturated bond; R1 is lower alkyl; R2 is prenyl group of formula VI (l, m and n are O or 1, with the proviso that 1+m+n≥2; a-f are H, a-b, c-d and e-f form bonds)] is added as an effective component to cream for external application, ointment, etc. for accelerating the heal of skin injury. The compound of formula I is obtained, e.g., by the alkali treatment of a compound of formula IV obtained by the reaction of a compound of formula II (X is halogen) with a compound of formula III in the presence of a condensing agent.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9317178A JPS5520713A (en) | 1978-08-01 | 1978-08-01 | Drug for external use for accelerating heal of skin injury |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9317178A JPS5520713A (en) | 1978-08-01 | 1978-08-01 | Drug for external use for accelerating heal of skin injury |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5520713A true JPS5520713A (en) | 1980-02-14 |
JPS6410495B2 JPS6410495B2 (en) | 1989-02-22 |
Family
ID=14075116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9317178A Granted JPS5520713A (en) | 1978-08-01 | 1978-08-01 | Drug for external use for accelerating heal of skin injury |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5520713A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07309710A (en) * | 1994-05-20 | 1995-11-28 | Eisai Co Ltd | External base |
JP2008214195A (en) * | 2007-02-28 | 2008-09-18 | Nagasaki Univ | Skin burn medicine and skin regeneration promoter |
WO2013052148A1 (en) * | 2011-10-04 | 2013-04-11 | Coyote Pharmaceuticals, Inc. | Geranylgeranylacetone derivatives |
US9045403B2 (en) | 2012-02-29 | 2015-06-02 | Coyote Pharmaceuticals, Inc. | Geranyl geranyl acetone (GGA) derivatives and compositions thereof |
US9119808B1 (en) | 2012-10-08 | 2015-09-01 | Coyote Pharmaceuticals, Inc. | Treating neurodegenerative diseases with GGA or a derivative thereof |
-
1978
- 1978-08-01 JP JP9317178A patent/JPS5520713A/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07309710A (en) * | 1994-05-20 | 1995-11-28 | Eisai Co Ltd | External base |
JP2008214195A (en) * | 2007-02-28 | 2008-09-18 | Nagasaki Univ | Skin burn medicine and skin regeneration promoter |
WO2013052148A1 (en) * | 2011-10-04 | 2013-04-11 | Coyote Pharmaceuticals, Inc. | Geranylgeranylacetone derivatives |
JP2014530810A (en) * | 2011-10-04 | 2014-11-20 | コヨーテ ファーマシューティカルズ インコーポレイテッド | Geranylgeranylacetone derivatives |
US9045403B2 (en) | 2012-02-29 | 2015-06-02 | Coyote Pharmaceuticals, Inc. | Geranyl geranyl acetone (GGA) derivatives and compositions thereof |
US9119808B1 (en) | 2012-10-08 | 2015-09-01 | Coyote Pharmaceuticals, Inc. | Treating neurodegenerative diseases with GGA or a derivative thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS6410495B2 (en) | 1989-02-22 |
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