JPS5531040A - Agent to promote absorption of drug through digestive tract - Google Patents
Agent to promote absorption of drug through digestive tractInfo
- Publication number
- JPS5531040A JPS5531040A JP10413078A JP10413078A JPS5531040A JP S5531040 A JPS5531040 A JP S5531040A JP 10413078 A JP10413078 A JP 10413078A JP 10413078 A JP10413078 A JP 10413078A JP S5531040 A JPS5531040 A JP S5531040A
- Authority
- JP
- Japan
- Prior art keywords
- organic
- absorption
- agent
- lower alkyl
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyrrole Compounds (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To provide a medicinal preparation having improved absorption through digestive tracts, by compounding an absorption-promoting agent comprising an enamine derivative of an organic aminocarboxylic acid or an organic aminosulfonic acid, to the effective components.
CONSTITUTION: A medicinal preparation composed of an effective component (e.g. antibiotics, remedy for digestive tracts, etc.) and an agent to promote the absorption of the effective component through the digestive tracts, comprising an enamine derivative of an organic aminocarboxylic acid or an organic aminosulfonic acid of formula I (the group II is residue derived from an organic aminocarboxylic acid or an organic aminosulfonic acid; R3 is H, lower alkyl, etc.; R4 is H, lower alkyl, etc.; R5 is lower alkyl, etc.,), e.g. DL-N-(1-methyl-2-ethoxycarbonylvinyl) alanine sodium salt. It is supposed that the high fat-solubility of the compound I contributes the promotion of the absorption.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53104130A JPS6050166B2 (en) | 1978-08-26 | 1978-08-26 | Drugs for gastrointestinal absorption |
ZA00794229A ZA794229B (en) | 1978-08-26 | 1979-08-13 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract |
AU49971/79A AU4997179A (en) | 1978-08-26 | 1979-08-16 | Enamine derivatives and use thereof |
US06/067,451 US4277465A (en) | 1978-08-26 | 1979-08-17 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract |
EP79103131A EP0009609A3 (en) | 1978-08-26 | 1979-08-24 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract, pharmaceutical composition comprising said adjuvant and process for preparing said pharmaceutical composition; enamine derivatives |
US06/210,578 US4352800A (en) | 1978-08-26 | 1980-11-26 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53104130A JPS6050166B2 (en) | 1978-08-26 | 1978-08-26 | Drugs for gastrointestinal absorption |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5531040A true JPS5531040A (en) | 1980-03-05 |
JPS6050166B2 JPS6050166B2 (en) | 1985-11-07 |
Family
ID=14372522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP53104130A Expired JPS6050166B2 (en) | 1978-08-26 | 1978-08-26 | Drugs for gastrointestinal absorption |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS6050166B2 (en) |
AU (1) | AU4997179A (en) |
ZA (1) | ZA794229B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997028117A1 (en) * | 1996-02-02 | 1997-08-07 | Sun A Pharm Co., Ltd. | Novel processes for producing l-glutamine and novel intermediates for synthesis thereof |
-
1978
- 1978-08-26 JP JP53104130A patent/JPS6050166B2/en not_active Expired
-
1979
- 1979-08-13 ZA ZA00794229A patent/ZA794229B/en unknown
- 1979-08-16 AU AU49971/79A patent/AU4997179A/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997028117A1 (en) * | 1996-02-02 | 1997-08-07 | Sun A Pharm Co., Ltd. | Novel processes for producing l-glutamine and novel intermediates for synthesis thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS6050166B2 (en) | 1985-11-07 |
ZA794229B (en) | 1980-11-26 |
AU4997179A (en) | 1980-03-06 |
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