JPS5531040A - Agent to promote absorption of drug through digestive tract - Google Patents

Agent to promote absorption of drug through digestive tract

Info

Publication number
JPS5531040A
JPS5531040A JP10413078A JP10413078A JPS5531040A JP S5531040 A JPS5531040 A JP S5531040A JP 10413078 A JP10413078 A JP 10413078A JP 10413078 A JP10413078 A JP 10413078A JP S5531040 A JPS5531040 A JP S5531040A
Authority
JP
Japan
Prior art keywords
organic
absorption
agent
lower alkyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10413078A
Other languages
Japanese (ja)
Other versions
JPS6050166B2 (en
Inventor
Ko Kamata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyoto Pharmaceutical Industries Ltd
Sawai Pharmaceutical Co Ltd
Original Assignee
Kyoto Pharmaceutical Industries Ltd
Sawai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries Ltd, Sawai Pharmaceutical Co Ltd filed Critical Kyoto Pharmaceutical Industries Ltd
Priority to JP53104130A priority Critical patent/JPS6050166B2/en
Priority to ZA00794229A priority patent/ZA794229B/en
Priority to AU49971/79A priority patent/AU4997179A/en
Priority to US06/067,451 priority patent/US4277465A/en
Priority to EP79103131A priority patent/EP0009609A3/en
Publication of JPS5531040A publication Critical patent/JPS5531040A/en
Priority to US06/210,578 priority patent/US4352800A/en
Publication of JPS6050166B2 publication Critical patent/JPS6050166B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To provide a medicinal preparation having improved absorption through digestive tracts, by compounding an absorption-promoting agent comprising an enamine derivative of an organic aminocarboxylic acid or an organic aminosulfonic acid, to the effective components.
CONSTITUTION: A medicinal preparation composed of an effective component (e.g. antibiotics, remedy for digestive tracts, etc.) and an agent to promote the absorption of the effective component through the digestive tracts, comprising an enamine derivative of an organic aminocarboxylic acid or an organic aminosulfonic acid of formula I (the group II is residue derived from an organic aminocarboxylic acid or an organic aminosulfonic acid; R3 is H, lower alkyl, etc.; R4 is H, lower alkyl, etc.; R5 is lower alkyl, etc.,), e.g. DL-N-(1-methyl-2-ethoxycarbonylvinyl) alanine sodium salt. It is supposed that the high fat-solubility of the compound I contributes the promotion of the absorption.
COPYRIGHT: (C)1980,JPO&Japio
JP53104130A 1978-08-26 1978-08-26 Drugs for gastrointestinal absorption Expired JPS6050166B2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP53104130A JPS6050166B2 (en) 1978-08-26 1978-08-26 Drugs for gastrointestinal absorption
ZA00794229A ZA794229B (en) 1978-08-26 1979-08-13 Adjuvant for promoting absorption of therapeutically active substances through the digestive tract
AU49971/79A AU4997179A (en) 1978-08-26 1979-08-16 Enamine derivatives and use thereof
US06/067,451 US4277465A (en) 1978-08-26 1979-08-17 Adjuvant for promoting absorption of therapeutically active substances through the digestive tract
EP79103131A EP0009609A3 (en) 1978-08-26 1979-08-24 Adjuvant for promoting absorption of therapeutically active substances through the digestive tract, pharmaceutical composition comprising said adjuvant and process for preparing said pharmaceutical composition; enamine derivatives
US06/210,578 US4352800A (en) 1978-08-26 1980-11-26 Adjuvant for promoting absorption of therapeutically active substances through the digestive tract

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53104130A JPS6050166B2 (en) 1978-08-26 1978-08-26 Drugs for gastrointestinal absorption

Publications (2)

Publication Number Publication Date
JPS5531040A true JPS5531040A (en) 1980-03-05
JPS6050166B2 JPS6050166B2 (en) 1985-11-07

Family

ID=14372522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53104130A Expired JPS6050166B2 (en) 1978-08-26 1978-08-26 Drugs for gastrointestinal absorption

Country Status (3)

Country Link
JP (1) JPS6050166B2 (en)
AU (1) AU4997179A (en)
ZA (1) ZA794229B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028117A1 (en) * 1996-02-02 1997-08-07 Sun A Pharm Co., Ltd. Novel processes for producing l-glutamine and novel intermediates for synthesis thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028117A1 (en) * 1996-02-02 1997-08-07 Sun A Pharm Co., Ltd. Novel processes for producing l-glutamine and novel intermediates for synthesis thereof

Also Published As

Publication number Publication date
JPS6050166B2 (en) 1985-11-07
ZA794229B (en) 1980-11-26
AU4997179A (en) 1980-03-06

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