JPS552637A - Cephalosporin derivative and its salt - Google Patents

Cephalosporin derivative and its salt

Info

Publication number
JPS552637A
JPS552637A JP7486878A JP7486878A JPS552637A JP S552637 A JPS552637 A JP S552637A JP 7486878 A JP7486878 A JP 7486878A JP 7486878 A JP7486878 A JP 7486878A JP S552637 A JPS552637 A JP S552637A
Authority
JP
Japan
Prior art keywords
compound
formula
methyl
salt
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7486878A
Other languages
Japanese (ja)
Inventor
Nobuhiro Oi
Bunya Aoki
Teizou Shinozaki
Kanji Moro
Isao Matsunaga
Takao Nofuji
Toshiyuki Nehashi
Yusuke Harada
Hisao Endo
Takao Kimura
Hiroshi Okazaki
Haruki Ogawa
Minoru Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP7486878A priority Critical patent/JPS552637A/en
Priority to DK225179A priority patent/DK225179A/en
Priority to AU47695/79A priority patent/AU524816B2/en
Priority to GB7919441A priority patent/GB2025944B/en
Priority to IL57480A priority patent/IL57480A/en
Priority to US06/047,781 priority patent/US4298605A/en
Priority to CA329,615A priority patent/CA1131617A/en
Priority to ZA792930A priority patent/ZA792930B/en
Priority to IT68273/79A priority patent/IT1192777B/en
Priority to NO792036A priority patent/NO792036L/en
Priority to CS794208A priority patent/CS212222B2/en
Priority to SU792781601A priority patent/SU1118289A3/en
Priority to NL7904846A priority patent/NL7904846A/en
Priority to PT69794A priority patent/PT69794A/en
Priority to SE7905520A priority patent/SE7905520L/en
Priority to DD79213817A priority patent/DD144412A5/en
Priority to HU79CU164A priority patent/HU178461B/en
Priority to FI791991A priority patent/FI791991A/en
Priority to BE2/57893A priority patent/BE877139A/en
Priority to FR7916089A priority patent/FR2429220A1/en
Priority to AT0440879A priority patent/AT365196B/en
Priority to DE2925302A priority patent/DE2925302C2/en
Priority to CH588179A priority patent/CH640859A5/en
Priority to YU01477/79A priority patent/YU147779A/en
Priority to ES481837A priority patent/ES481837A1/en
Priority to AR277005A priority patent/AR231449A1/en
Priority to IE1182/79A priority patent/IE48581B1/en
Publication of JPS552637A publication Critical patent/JPS552637A/en
Priority to ES489648A priority patent/ES8103100A1/en
Priority to ES489645A priority patent/ES8103099A1/en
Priority to ES489646A priority patent/ES8104303A1/en
Priority to ES489647A priority patent/ES8104305A1/en
Priority to US06/136,063 priority patent/US4328224A/en
Priority to US06/136,062 priority patent/US4301161A/en
Priority to US06/136,061 priority patent/US4341776A/en
Priority to CS802741A priority patent/CS212225B2/en
Priority to AT0115181A priority patent/AT371821B/en
Priority to AR284639A priority patent/AR231294A1/en
Priority to YU00546/83A priority patent/YU54683A/en
Priority to YU00545/83A priority patent/YU54583A/en
Priority to YU00543/83A priority patent/YU54383A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I: (R is H or OH) or its salt.
EXAMPLE: 7-[D(-)-α-{3-(3,4-Dihydroxybenzoyl)-3-methyl-1-ureido}-α-phenyl- acetamido]-3-(1-methyl-1H-tetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acid.
USE: Antibacterials particularly effective against bacteria which belong to the genuses Pseudomas and Serratia compared with cephalosporin antibacterials, e.g. Cefazolin and Cephaloridine.
PROCESS: A compound of formula II is reacted with 7-amino-3-(1-methyl-1H- tetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acid or its derivative to give the objective compound. Alternatively, the group of formula IV is introduced into the α- amino group of the compound of formula III.
COPYRIGHT: (C)1980,JPO&Japio
JP7486878A 1978-06-22 1978-06-22 Cephalosporin derivative and its salt Pending JPS552637A (en)

Priority Applications (40)

Application Number Priority Date Filing Date Title
JP7486878A JPS552637A (en) 1978-06-22 1978-06-22 Cephalosporin derivative and its salt
DK225179A DK225179A (en) 1978-06-22 1979-05-30 PROCEDURE FOR PREPARING CEPHALOSPORINE DERIVATIVES
AU47695/79A AU524816B2 (en) 1978-06-22 1979-06-01 Cephalosporin derivatives
GB7919441A GB2025944B (en) 1978-06-22 1979-06-04 Cephalosporins
IL57480A IL57480A (en) 1978-06-22 1979-06-05 Benzoylureido cephalosporin derivatives,their preparation and antibacterial preparations containing them
US06/047,781 US4298605A (en) 1978-06-22 1979-06-11 Cephalosporin derivatives
CA329,615A CA1131617A (en) 1978-06-22 1979-06-12 Cephalosporin derivatives
ZA792930A ZA792930B (en) 1978-06-22 1979-06-13 Cephalosporin derivatives
IT68273/79A IT1192777B (en) 1978-06-22 1979-06-14 Cephalosporin derivatives
NO792036A NO792036L (en) 1978-06-22 1979-06-19 PROCEDURE FOR THE PREPARATION OF CEPHALOSPORINS
CS794208A CS212222B2 (en) 1978-06-22 1979-06-19 Method of preparation of the 7-(substituted benzoylureido)-phenyl acetamido derivatives of the cephalosporine
SU792781601A SU1118289A3 (en) 1978-06-22 1979-06-21 Method of obtaining cephalosporin derivatives
NL7904846A NL7904846A (en) 1978-06-22 1979-06-21 CEPHALOSPORIN DERIVATIVE, ITS PREPARATION AND USE IN AN ANTIBACTERIAL PREPARATION.
PT69794A PT69794A (en) 1978-06-22 1979-06-21 Sephalosporin derivatives
SE7905520A SE7905520L (en) 1978-06-22 1979-06-21 cephalosporin derivatives
DD79213817A DD144412A5 (en) 1978-06-22 1979-06-21 PROCESS FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES
HU79CU164A HU178461B (en) 1978-06-22 1979-06-21 Process for producing 7-square bracket-bracket-benzoyl-ureido-bracket closed-phenyl-acetamido-square bracket closed-3-methyl-3-c3pheme-4-carboxylic acids
FI791991A FI791991A (en) 1978-06-22 1979-06-21 KEFALOSPORINDERIVAT
BE2/57893A BE877139A (en) 1978-06-22 1979-06-21 CEPHALOSPORIN DERIVATIVES
FR7916089A FR2429220A1 (en) 1978-06-22 1979-06-22 CEPHALOSPORIN DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
AT0440879A AT365196B (en) 1978-06-22 1979-06-22 METHOD FOR PRODUCING NEW CEPHALOSPORINE COMPOUNDS
DE2925302A DE2925302C2 (en) 1978-06-22 1979-06-22 Acylureidocephalosporin derivatives and their use
CH588179A CH640859A5 (en) 1978-06-22 1979-06-22 CEPHALOSPORINE DERIVATIVES.
YU01477/79A YU147779A (en) 1978-06-22 1979-06-22 Process for preparing new cephalosporin derivatives
ES481837A ES481837A1 (en) 1978-06-22 1979-06-22 Cephalosporin derivatives
AR277005A AR231449A1 (en) 1978-06-22 1979-07-22 PROCEDURE FOR THE PREPARATION OF A BENZOIL-UREIDO-ACETAMIDO-CEFEM-CARBOXILICO ACID DERIVATIVE
IE1182/79A IE48581B1 (en) 1978-06-22 1979-08-08 Benzolylureido-phenyl acetamido cephalosporins
ES489645A ES8103099A1 (en) 1978-06-22 1980-03-17 Cephalosporin derivatives
ES489646A ES8104303A1 (en) 1978-06-22 1980-03-17 Cephalosporin derivatives
ES489647A ES8104305A1 (en) 1978-06-22 1980-03-17 Cephalosporin derivatives
ES489648A ES8103100A1 (en) 1978-06-22 1980-03-17 Cephalosporin derivatives
US06/136,063 US4328224A (en) 1978-06-22 1980-03-28 Cephalosporin derivatives
US06/136,062 US4301161A (en) 1978-06-22 1980-03-28 Cephalosporin derivatives
US06/136,061 US4341776A (en) 1978-06-22 1980-03-28 Cephalosporin derivatives
CS802741A CS212225B2 (en) 1978-06-22 1980-04-18 Method of preparation of the 7-(substituted benzoylureido)-phenyl-acetamido derivatives of the cephalosporine
AT0115181A AT371821B (en) 1978-06-22 1981-03-12 METHOD FOR PRODUCING NEW CEPHALOSPORINE DERIVATIVES
AR284639A AR231294A1 (en) 1978-06-22 1981-03-17 PROCEDURE FOR THE PREPARATION OF A BENZOIL-UREIDO-ACETAMIDO-CEFEM-CARBOXILICO ACID DERIVATIVE
YU00546/83A YU54683A (en) 1978-06-22 1983-03-07 Process for obtining new cephalosporin derivatives
YU00545/83A YU54583A (en) 1978-06-22 1983-03-07 Process for obtaining new cephalosporin derivatives
YU00543/83A YU54383A (en) 1978-06-22 1983-03-07 Process for obtaining new cephalosporin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7486878A JPS552637A (en) 1978-06-22 1978-06-22 Cephalosporin derivative and its salt

Publications (1)

Publication Number Publication Date
JPS552637A true JPS552637A (en) 1980-01-10

Family

ID=13559731

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7486878A Pending JPS552637A (en) 1978-06-22 1978-06-22 Cephalosporin derivative and its salt

Country Status (2)

Country Link
JP (1) JPS552637A (en)
ZA (1) ZA792930B (en)

Also Published As

Publication number Publication date
ZA792930B (en) 1980-08-27

Similar Documents

Publication Publication Date Title
ES8407495A1 (en) Crystalline acid addition salts of cephalosporins and process for their preparation.
JPS56125392A (en) Cepham and cephem compound and preparation thereof
JPS5777689A (en) Novel cephen compound, or its salt, its preparation, and preventive it as active ingredient
JPS5612368A (en) Optically pure heterocyclic amino acid compounds* their manufacture and their use for synthesizing drug
JPS5798288A (en) Novel cephem compound or its salt, their preparation, and preventive and remedy for bacteriosis containing said compound as active component
JPS56118085A (en) 2-methylcephalosporin derivative and its preparation
JPS5535096A (en) 3-cephem compound, its salt, their preparation, and preventive and remedy for microbism comprising thema active constituent
JPS5533500A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism
JPS552637A (en) Cephalosporin derivative and its salt
JPS6485A (en) Novel cephalosporin derivative
JPS5690088A (en) Novel cephalosporin analog compound
JPS5746990A (en) Novel cephalexin derivative and its preparation
PT69490A (en) PROCESS FOR THE PREPARATION OF NOVEL OXIMES DERIVED FROM 3-AZIDOMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID
JPS54117493A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them
JPS5246093A (en) 2-alkyl-7-substituted-2, or 3-cephem-4-carboxylic compounds, their sal ts, and preparation thereof
JPS5511600A (en) Cephem compound, its salt, their preparation and remedy and prophylactic for microbism containing mainly the same
JPS56115788A (en) Azetidinone derivative and its preparation
JPS57142961A (en) Basic substituted anthranilic acid
JPS55149295A (en) Novel cephalosporin compound and its preparation
JPS5645461A (en) Alpha-amino acid derivative
JPS56131591A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, preparation thereof and preventing agent and remedy for microbism containing the same as active consitutent
JPS55149288A (en) Cephalosporanic acid derivative having pyrimidine or its salt
JPS54144392A (en) Cephalosporin derivative
JPS5572195A (en) Novel cephalosporin and antibacterial comprising it as active constituent
JPS55115886A (en) Preparation of cepham and cephem compound