JPS5524138A - Optically active synthetic intermediate and its preparation - Google Patents
Optically active synthetic intermediate and its preparationInfo
- Publication number
- JPS5524138A JPS5524138A JP9738878A JP9738878A JPS5524138A JP S5524138 A JPS5524138 A JP S5524138A JP 9738878 A JP9738878 A JP 9738878A JP 9738878 A JP9738878 A JP 9738878A JP S5524138 A JPS5524138 A JP S5524138A
- Authority
- JP
- Japan
- Prior art keywords
- optically active
- configuration
- line represents
- synthetic intermediate
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
NEW MATERIAL:An optically active compound of formula I [R1 is H or OH-protecting group; X is CHO, CH(SR2)2, etc.; R2 is alkyl, aryl; R3 is alkylene; the dotted line represents α-configulation; the thick solid line represents β-configuration; the wavy line represents α-configuration, β-configuration or their mixture].
EXAMPLE: (3aR,5R,6aS)-4-Bis(ethylthio)methyl-5-hydroxymethyl-2-oxo-hexahydro- 2H-cyclopenta(b)furan.
USE: A synthetic intermediate of a medicine such as an optically active prostaglandin.
PROCESS: The compound I is prepared by reacting the optically active compound II (Z is O, S; R4 is H, alkyl, aryl) with a thiol compound III or IV in the presence of an acid, and if necessary hydrolyzing the produced thioacetal.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9738878A JPS5524138A (en) | 1978-08-11 | 1978-08-11 | Optically active synthetic intermediate and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9738878A JPS5524138A (en) | 1978-08-11 | 1978-08-11 | Optically active synthetic intermediate and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5524138A true JPS5524138A (en) | 1980-02-21 |
JPS6216950B2 JPS6216950B2 (en) | 1987-04-15 |
Family
ID=14191124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9738878A Granted JPS5524138A (en) | 1978-08-11 | 1978-08-11 | Optically active synthetic intermediate and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5524138A (en) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4914458A (en) * | 1972-04-27 | 1974-02-07 | ||
JPS49101367A (en) * | 1973-01-31 | 1974-09-25 |
-
1978
- 1978-08-11 JP JP9738878A patent/JPS5524138A/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4914458A (en) * | 1972-04-27 | 1974-02-07 | ||
JPS49101367A (en) * | 1973-01-31 | 1974-09-25 |
Also Published As
Publication number | Publication date |
---|---|
JPS6216950B2 (en) | 1987-04-15 |
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