JPS57150626A - Novel bicyclooctane derivative, its salt and their preparation - Google Patents
Novel bicyclooctane derivative, its salt and their preparationInfo
- Publication number
- JPS57150626A JPS57150626A JP56149769A JP14976981A JPS57150626A JP S57150626 A JPS57150626 A JP S57150626A JP 56149769 A JP56149769 A JP 56149769A JP 14976981 A JP14976981 A JP 14976981A JP S57150626 A JPS57150626 A JP S57150626A
- Authority
- JP
- Japan
- Prior art keywords
- hydroxy
- compound
- alkyl
- salt
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:The bicyclooctane derivative of formulaI[X1 is free or esterified carboxyl, hydroxymethyl, cyano, etc.; Y is ethylene or vinylene; R1 is H or hydroxy; R2 is H or together with R1 form a single bond; R3 is hydroxy; R4 is H or lower alkyl; R5 is H, alkenyl, alkynyl, alkyl, lower cycloalkyl, etc.; A is Ch=CH or group of formula II; R6 and R7 are H, etc.; m1 is 1 or 2; m2 is 0W2; excluding the compound of formula III (Z and Z' are H, etc.; R8 is H, alkyl, etc.; R9 is H or lower alkyl)].
EXAMPLE: 2β-(3'-Hydroxy-trans-1'-octenyl)3α-hydroxy-7-(o-cyanobenzyloxy)-cis-bicyclo-[3,3,0]octane.
USE: Useful as a remedy for ulcer having low side effects.
PROCESS: The compound of formulaIcan be prepared by reacting the compound of formula IV (X2 is carboxyl, etc.) e.g. with a reducing agent.
COPYRIGHT: (C)1982,JPO&Japio
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/243,570 US4493846A (en) | 1980-03-21 | 1981-03-13 | Bicyclooctane derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57150626A true JPS57150626A (en) | 1982-09-17 |
Family
ID=22919263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56149769A Pending JPS57150626A (en) | 1981-03-13 | 1981-09-21 | Novel bicyclooctane derivative, its salt and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57150626A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009041715A (en) * | 2007-08-10 | 2009-02-26 | Nsk Ltd | Toroidal type continuously variable transmission |
-
1981
- 1981-09-21 JP JP56149769A patent/JPS57150626A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009041715A (en) * | 2007-08-10 | 2009-02-26 | Nsk Ltd | Toroidal type continuously variable transmission |
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