JPS5519234A - Optical resolution of amino acid ester - Google Patents
Optical resolution of amino acid esterInfo
- Publication number
- JPS5519234A JPS5519234A JP9183378A JP9183378A JPS5519234A JP S5519234 A JPS5519234 A JP S5519234A JP 9183378 A JP9183378 A JP 9183378A JP 9183378 A JP9183378 A JP 9183378A JP S5519234 A JPS5519234 A JP S5519234A
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid esters
- esters
- enantiomer
- enantiomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain optically active substances of title esters useful as raw materials of synthetic sweetener, etc., by reacting recemic amino acid esters with specific dipeptide derivatives to form precipitates with only one enantiomer of said esters.
CONSTITUTION: Racemic amino acid esters are reacted with optically active dipeptide derivatives of formula (X is benzyloxycarbonyl; R is lower alkyl) in a solution. In the two enantiomers of racemic amino acid esters, only the enantiomer which has enantiomeric relationship to the compounds of formula reacts to form an adduct and precipitates. The amount of the optically resolving agents is preferably in a ratio of 0.1-5 equivalents based on said racematers. the amount used is adjusted depending upon which of both enantiomers remaining in a precipitate or a solution is desired to have higher optical purity.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9183378A JPS5519234A (en) | 1978-07-27 | 1978-07-27 | Optical resolution of amino acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9183378A JPS5519234A (en) | 1978-07-27 | 1978-07-27 | Optical resolution of amino acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5519234A true JPS5519234A (en) | 1980-02-09 |
JPS6256857B2 JPS6256857B2 (en) | 1987-11-27 |
Family
ID=14037589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9183378A Granted JPS5519234A (en) | 1978-07-27 | 1978-07-27 | Optical resolution of amino acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5519234A (en) |
-
1978
- 1978-07-27 JP JP9183378A patent/JPS5519234A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6256857B2 (en) | 1987-11-27 |
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