JPS55162997A - Preparation of n1-oxidepurine-arabinoside - Google Patents

Preparation of n1-oxidepurine-arabinoside

Info

Publication number
JPS55162997A
JPS55162997A JP7040179A JP7040179A JPS55162997A JP S55162997 A JPS55162997 A JP S55162997A JP 7040179 A JP7040179 A JP 7040179A JP 7040179 A JP7040179 A JP 7040179A JP S55162997 A JPS55162997 A JP S55162997A
Authority
JP
Japan
Prior art keywords
arabinoside
oxidepurine
microorganism
reaction
hypoxanthine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7040179A
Other languages
Japanese (ja)
Other versions
JPS5726117B2 (en
Inventor
Takashi Udagawa
Wataru Nakamatsu
Shigeru Yamanaka
Hirokazu Morisawa
Akihiro Yamazaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP7040179A priority Critical patent/JPS55162997A/en
Publication of JPS55162997A publication Critical patent/JPS55162997A/en
Publication of JPS5726117B2 publication Critical patent/JPS5726117B2/ja
Granted legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: The reaction of N1-oxidepurine with uracyl-arabinoside or cytosine- arabinose is effected by the action of a specific microorganism in an aqueous solution to accumulate a large amount of N1-oxidepurine-arabinoside in the reaction mixture.
CONSTITUTION: A microorganism belonging to Pseudomonas, Flavobacterium, or Klebsiella is provided, for example, Klebsiella pneumonia ATCC 9621. In the presence of the microorganism, the reaction of N1-oxidepurine of formula I such as hypoxanthine with uracil-arabinoside, cytosine-arabinoside or arabinose-1-phosphate is effected to form N1-oxidepurine-arabinoside of formula II, for example, hypoxanthine-arabinoside-N1-oxide. In the reaction, the cells of the microorganism or its processed product and the reagents are dissolved or suspended in an aqueous reaction mixture and the temperature is kept at 10W70°C and 4W10pH to accumulate N1-oxidepurine-arabinoside.
COPYRIGHT: (C)1980,JPO&Japio
JP7040179A 1979-06-05 1979-06-05 Preparation of n1-oxidepurine-arabinoside Granted JPS55162997A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7040179A JPS55162997A (en) 1979-06-05 1979-06-05 Preparation of n1-oxidepurine-arabinoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7040179A JPS55162997A (en) 1979-06-05 1979-06-05 Preparation of n1-oxidepurine-arabinoside

Publications (2)

Publication Number Publication Date
JPS55162997A true JPS55162997A (en) 1980-12-18
JPS5726117B2 JPS5726117B2 (en) 1982-06-02

Family

ID=13430387

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7040179A Granted JPS55162997A (en) 1979-06-05 1979-06-05 Preparation of n1-oxidepurine-arabinoside

Country Status (1)

Country Link
JP (1) JPS55162997A (en)

Also Published As

Publication number Publication date
JPS5726117B2 (en) 1982-06-02

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