JPS55161801A - Fluorescence-labeled acid mucopolysaccharide and preparation thereof - Google Patents
Fluorescence-labeled acid mucopolysaccharide and preparation thereofInfo
- Publication number
- JPS55161801A JPS55161801A JP6996079A JP6996079A JPS55161801A JP S55161801 A JPS55161801 A JP S55161801A JP 6996079 A JP6996079 A JP 6996079A JP 6996079 A JP6996079 A JP 6996079A JP S55161801 A JPS55161801 A JP S55161801A
- Authority
- JP
- Japan
- Prior art keywords
- acid
- fluoresceinamide
- condroitin
- sulfuric
- fluorescence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 9
- 229920002683 Glycosaminoglycan Polymers 0.000 title abstract 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 2
- GZAJOEGTZDUSKS-UHFFFAOYSA-N 5-aminofluorescein Chemical compound C12=CC=C(O)C=C2OC2=CC(O)=CC=C2C21OC(=O)C1=CC(N)=CC=C21 GZAJOEGTZDUSKS-UHFFFAOYSA-N 0.000 abstract 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 2
- 239000012736 aqueous medium Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000009833 condensation Methods 0.000 abstract 2
- 229920000669 heparin Polymers 0.000 abstract 2
- 229960002897 heparin Drugs 0.000 abstract 2
- 229920002674 hyaluronan Polymers 0.000 abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract 2
- 230000007935 neutral effect Effects 0.000 abstract 2
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6996079A JPS55161801A (en) | 1979-06-06 | 1979-06-06 | Fluorescence-labeled acid mucopolysaccharide and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6996079A JPS55161801A (en) | 1979-06-06 | 1979-06-06 | Fluorescence-labeled acid mucopolysaccharide and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55161801A true JPS55161801A (en) | 1980-12-16 |
| JPS6317843B2 JPS6317843B2 (enrdf_load_stackoverflow) | 1988-04-15 |
Family
ID=13417719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6996079A Granted JPS55161801A (en) | 1979-06-06 | 1979-06-06 | Fluorescence-labeled acid mucopolysaccharide and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS55161801A (enrdf_load_stackoverflow) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047020A (en) * | 1987-09-14 | 1991-09-10 | Baxter International Inc. | Ionic heparin coating |
| JP2002519481A (ja) * | 1998-07-06 | 2002-07-02 | フィディア・アドバンスト・バイオポリマーズ・ソシエタ・ア・レスポンサビリタ・リミタータ | ヒアルロン酸アミドおよびそれらの誘導体、並びにそれらの製造法 |
| US7863256B2 (en) | 2005-03-02 | 2011-01-04 | Fidia Farmaceutici S.P.A. | Amide derivatives of hyaluronic acid in osteoarthrosis |
| CN103319626A (zh) * | 2013-07-04 | 2013-09-25 | 协和生物制药(天津)有限公司 | 一种透明质酸与含异硫氰基的有机分子共价连接的方法 |
| CN108559008A (zh) * | 2018-06-25 | 2018-09-21 | 浙江大学 | 一种具有聚集诱导发光特性的季铵化壳聚糖/肝素复合纳米荧光探针及其制备方法 |
| JP2019512563A (ja) * | 2016-03-22 | 2019-05-16 | オーボ アカデミー ユニヴァーシティー | 蛍光増白剤としての多糖誘導体 |
-
1979
- 1979-06-06 JP JP6996079A patent/JPS55161801A/ja active Granted
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047020A (en) * | 1987-09-14 | 1991-09-10 | Baxter International Inc. | Ionic heparin coating |
| JP2002519481A (ja) * | 1998-07-06 | 2002-07-02 | フィディア・アドバンスト・バイオポリマーズ・ソシエタ・ア・レスポンサビリタ・リミタータ | ヒアルロン酸アミドおよびそれらの誘導体、並びにそれらの製造法 |
| JP2007031721A (ja) * | 1998-07-06 | 2007-02-08 | Fidia Farmaceutici Spa | ヒアルロン酸アミドおよびそれらの誘導体、並びにそれらの製造法 |
| US7884087B1 (en) | 1998-07-06 | 2011-02-08 | Fidia Farmaceutici S.P.A. | Amides of hyaluronic acid the derivatives thereof and a process for their preparation |
| US8575129B2 (en) | 1998-07-06 | 2013-11-05 | Fidia Farmaceutici S.P.A. | Amides of hyaluronic acid and the derivatives thereof and a process for their preparation |
| US7863256B2 (en) | 2005-03-02 | 2011-01-04 | Fidia Farmaceutici S.P.A. | Amide derivatives of hyaluronic acid in osteoarthrosis |
| CN103319626A (zh) * | 2013-07-04 | 2013-09-25 | 协和生物制药(天津)有限公司 | 一种透明质酸与含异硫氰基的有机分子共价连接的方法 |
| JP2019512563A (ja) * | 2016-03-22 | 2019-05-16 | オーボ アカデミー ユニヴァーシティー | 蛍光増白剤としての多糖誘導体 |
| US10988716B2 (en) | 2016-03-22 | 2021-04-27 | Abo Akademi University | Polysaccharide derivatives as optical brightening agents |
| CN108559008A (zh) * | 2018-06-25 | 2018-09-21 | 浙江大学 | 一种具有聚集诱导发光特性的季铵化壳聚糖/肝素复合纳米荧光探针及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6317843B2 (enrdf_load_stackoverflow) | 1988-04-15 |
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