JPS55153768A - 4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component - Google Patents
4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective componentInfo
- Publication number
- JPS55153768A JPS55153768A JP5932380A JP5932380A JPS55153768A JP S55153768 A JPS55153768 A JP S55153768A JP 5932380 A JP5932380 A JP 5932380A JP 5932380 A JP5932380 A JP 5932380A JP S55153768 A JPS55153768 A JP S55153768A
- Authority
- JP
- Japan
- Prior art keywords
- cyanophenyl
- preparation
- formula
- same
- effective component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Title compounds of formula I (R1 is n-propxycarbonyl, isobutoxycarbonyl, neopentyloxycarbonyl; R2 is lower alkyl; R4 is lower dialkoxymethl, formyl, hydroxyiminomethyl, cyano) or their salts permissible as medicines.
EXAMPLE: n-Propyl 6-dimethoxymethyl-2-methyl-4-(2-cyanophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxyiate.
USE: Vasodilator: they are used to treat cardiovascular diseases such as coronary insufficiency, stenocardia, or myocardiac infarction.
PREPARATION: In an example, the reaction between a compound of formula II (Ra 4 is lower dialkoxymethyl) and an amine of formula III is effected to give one of compounds of formula IV.
COPYRIGHT: (C)1980,JPO&Japio
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7916505 | 1979-05-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55153768A true JPS55153768A (en) | 1980-11-29 |
Family
ID=10505106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5932380A Pending JPS55153768A (en) | 1979-05-11 | 1980-05-02 | 4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55153768A (en) |
-
1980
- 1980-05-02 JP JP5932380A patent/JPS55153768A/en active Pending
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