JPS55153768A - 4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component - Google Patents

4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component

Info

Publication number
JPS55153768A
JPS55153768A JP5932380A JP5932380A JPS55153768A JP S55153768 A JPS55153768 A JP S55153768A JP 5932380 A JP5932380 A JP 5932380A JP 5932380 A JP5932380 A JP 5932380A JP S55153768 A JPS55153768 A JP S55153768A
Authority
JP
Japan
Prior art keywords
cyanophenyl
preparation
formula
same
effective component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5932380A
Other languages
Japanese (ja)
Inventor
Yoshinari Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS55153768A publication Critical patent/JPS55153768A/en
Pending legal-status Critical Current

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  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Title compounds of formula I (R1 is n-propxycarbonyl, isobutoxycarbonyl, neopentyloxycarbonyl; R2 is lower alkyl; R4 is lower dialkoxymethl, formyl, hydroxyiminomethyl, cyano) or their salts permissible as medicines.
EXAMPLE: n-Propyl 6-dimethoxymethyl-2-methyl-4-(2-cyanophenyl)-5-methoxycarbonyl-1,4-dihydropyridine-3-carboxyiate.
USE: Vasodilator: they are used to treat cardiovascular diseases such as coronary insufficiency, stenocardia, or myocardiac infarction.
PREPARATION: In an example, the reaction between a compound of formula II (Ra 4 is lower dialkoxymethyl) and an amine of formula III is effected to give one of compounds of formula IV.
COPYRIGHT: (C)1980,JPO&Japio
JP5932380A 1979-05-11 1980-05-02 4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component Pending JPS55153768A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7916505 1979-05-11

Publications (1)

Publication Number Publication Date
JPS55153768A true JPS55153768A (en) 1980-11-29

Family

ID=10505106

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5932380A Pending JPS55153768A (en) 1979-05-11 1980-05-02 4-cyanophenyl-1,4-dihydropyridine compound, its preparation, and vasodilator containing the same as effective component

Country Status (1)

Country Link
JP (1) JPS55153768A (en)

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