JPS55143976A - 33alkoxyy66alkylidnehydradinopyridazine optically active isomer*its mixture and its nontoxic salt - Google Patents

33alkoxyy66alkylidnehydradinopyridazine optically active isomer*its mixture and its nontoxic salt

Info

Publication number
JPS55143976A
JPS55143976A JP5409680A JP5409680A JPS55143976A JP S55143976 A JPS55143976 A JP S55143976A JP 5409680 A JP5409680 A JP 5409680A JP 5409680 A JP5409680 A JP 5409680A JP S55143976 A JPS55143976 A JP S55143976A
Authority
JP
Japan
Prior art keywords
mixture
optically active
active isomer
nontoxic salt
nontoxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5409680A
Other languages
English (en)
Other versions
JPS6254305B2 (ja
Inventor
Dorigotsuteii Ruchiaano
Gabiragi Jiyobanni
Pinza Mario
Pifueri Jiyorujio
Semeraro Kuraudeio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ISF SpA
Original Assignee
ISF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ISF SpA filed Critical ISF SpA
Publication of JPS55143976A publication Critical patent/JPS55143976A/ja
Publication of JPS6254305B2 publication Critical patent/JPS6254305B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22Nitrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP5409680A 1979-04-23 1980-04-22 33alkoxyy66alkylidnehydradinopyridazine optically active isomer*its mixture and its nontoxic salt Granted JPS55143976A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22035/79A IT1165040B (it) 1979-04-23 1979-04-23 Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
JPS55143976A true JPS55143976A (en) 1980-11-10
JPS6254305B2 JPS6254305B2 (ja) 1987-11-13

Family

ID=11190502

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5409680A Granted JPS55143976A (en) 1979-04-23 1980-04-22 33alkoxyy66alkylidnehydradinopyridazine optically active isomer*its mixture and its nontoxic salt

Country Status (15)

Country Link
US (1) US4324788A (ja)
EP (1) EP0018016B1 (ja)
JP (1) JPS55143976A (ja)
AR (1) AR223521A1 (ja)
AT (1) ATE4423T1 (ja)
CA (1) CA1132982A (ja)
DE (1) DE3064520D1 (ja)
DK (1) DK147887C (ja)
ES (1) ES8104247A1 (ja)
IL (1) IL59882A (ja)
IT (1) IT1165040B (ja)
MX (1) MX6327E (ja)
NO (1) NO158737C (ja)
PT (1) PT71126B (ja)
YU (1) YU42505B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711887A (en) * 1982-04-23 1987-12-08 Imperial Chemical Industries Plc Hydrazinopyridazine compounds
US4599333A (en) * 1982-06-14 1986-07-08 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
EP0097202B1 (en) * 1982-06-23 1987-11-19 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
US4517188A (en) * 1983-05-09 1985-05-14 Mead Johnson & Company 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols
IT1208003B (it) * 1987-01-08 1989-06-01 Isf Spa Procedimento per preparare derivati alcossi alchiliden, idrazino, piridazinici.
US5082939A (en) * 1987-01-08 1992-01-21 I.S.F. Societa Per Azioni Pyridazine derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1054107B (it) * 1970-12-15 1981-11-10 Isf Spa Nuove 3,idrazinopiridazine 6,sostituite ad attivita antiiperten siva e loro preparazione
AR208397A1 (es) * 1973-02-20 1976-12-27 Ciba Geigy Ag Procedimiento para la elaboracion de compuestos de 1-piridiloxi-2-hidroxi-3-amino-propano1-piraziniloxi-2-hidroxi-3-amino-propano y 1-pirimidiniloxi-2-hidroxi-3-amino-propan
US4115575A (en) * 1973-02-20 1978-09-19 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
CH591448A5 (ja) * 1974-05-14 1977-09-15 Ciba Geigy Ag
GB1527712A (en) 1974-06-18 1978-10-11 Smith Kline French Lab Hydrazinopyridazines
US4082843A (en) * 1975-11-26 1978-04-04 Smith Kline & French Laboratories Limited 3-(3-(3-Substituted amino-2-hydroxypropoxy)phenyl)-6-hydrazino pyridazines and their use as vasodilators and β-adrenergic blocking agents
BE836633A (fr) 1975-12-15 1976-06-15 Phenylhydrazinopyridazines

Also Published As

Publication number Publication date
PT71126A (en) 1980-05-01
NO158737C (no) 1988-10-26
PT71126B (en) 1981-08-07
EP0018016B1 (de) 1983-08-10
NO158737B (no) 1988-07-18
DK147887C (da) 1985-08-19
CA1132982A (en) 1982-10-05
US4324788A (en) 1982-04-13
IT7922035A0 (it) 1979-04-23
JPS6254305B2 (ja) 1987-11-13
IT1165040B (it) 1987-04-22
ATE4423T1 (de) 1983-08-15
AR223521A1 (es) 1981-08-31
DK169280A (da) 1980-10-24
IL59882A0 (en) 1980-06-30
IL59882A (en) 1984-06-29
ES490620A0 (es) 1981-04-16
YU108580A (en) 1983-02-28
ES8104247A1 (es) 1981-04-16
EP0018016A1 (de) 1980-10-29
DK147887B (da) 1985-01-02
MX6327E (es) 1985-04-10
NO801162L (no) 1980-10-24
YU42505B (en) 1988-10-31
DE3064520D1 (en) 1983-09-15

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