JPS55115900A - Novel macrolide antibiotic substance a11725 3 and its preparation - Google Patents

Novel macrolide antibiotic substance a11725 3 and its preparation

Info

Publication number
JPS55115900A
JPS55115900A JP2478879A JP2478879A JPS55115900A JP S55115900 A JPS55115900 A JP S55115900A JP 2478879 A JP2478879 A JP 2478879A JP 2478879 A JP2478879 A JP 2478879A JP S55115900 A JPS55115900 A JP S55115900A
Authority
JP
Japan
Prior art keywords
antibiotic substance
methanol
iii
aqueous solution
antibacterial agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2478879A
Other languages
Japanese (ja)
Other versions
JPS6118557B2 (en
Inventor
Tadayo Fujii
Shuzo Satoi
Naoki Muto
Seiji Katsumata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP2478879A priority Critical patent/JPS55115900A/en
Priority to CA326,416A priority patent/CA1125203A/en
Priority to GB7915807A priority patent/GB2020647B/en
Priority to NL7903601A priority patent/NL192621C/en
Priority to ES480405A priority patent/ES480405A1/en
Priority to DE19792918711 priority patent/DE2918711A1/en
Priority to DE2954218A priority patent/DE2954218C2/en
Priority to IT22536/79A priority patent/IT1113372B/en
Priority to US06/037,846 priority patent/US4291021A/en
Priority to FR7911883A priority patent/FR2425444A1/en
Publication of JPS55115900A publication Critical patent/JPS55115900A/en
Publication of JPS6118557B2 publication Critical patent/JPS6118557B2/ja
Granted legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

NEW MATERIAL:An antibiotic substance A11725 III (and its salt) having the following characteristics: color, white; molecular formula C36H59NO11; molecular weight, 681; melting point, 99W102°C; [α]D, -2.3° (c=1.0%, methanol); positive to potassium permanganate solution decolorizing reaction; basic; solubility, soluble in an acidic aqueous solution, methanol, acetone, benzene, etc., slightly soluble in an alkaline aqueous solution, insoluble in hexane, etc.
EXAMPLE: Antibacterial agent effective to infectious respiratory diseases caused by gram-positive bacteria, e.g. staphylococci. Feed additive and antibacterial agent for the remedy of animal diseases.
PROCESS: Bacteria capable of producing antibiotic substance A11725 III, e.g. Micromonospora sp A11725, are inoculated in a medium containing assimilable carbon source and nitrogen source, and inorganic substances, and cultured under aerobical conditions. The objective substance is separated from the cultured product.
COPYRIGHT: (C)1980,JPO&Japio
JP2478879A 1978-05-10 1979-03-02 Novel macrolide antibiotic substance a11725 3 and its preparation Granted JPS55115900A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2478879A JPS55115900A (en) 1979-03-02 1979-03-02 Novel macrolide antibiotic substance a11725 3 and its preparation
CA326,416A CA1125203A (en) 1978-05-10 1979-04-26 Macrolide antibiotics from micromonospora
GB7915807A GB2020647B (en) 1978-05-10 1979-05-08 Macrolide antibiotics a 11725 1 2 and 3 preparation thereo
NL7903601A NL192621C (en) 1978-05-10 1979-05-08 Method for the preparation of new antibiotics, which belong to the macrolides, microorganisms of the strain Micromonospora, which are capable of producing these new antibiotics; and new antibiotics and pharmaceutical preparations.
ES480405A ES480405A1 (en) 1978-05-10 1979-05-09 Novel macrolide antibiotics and preparation thereof
DE19792918711 DE2918711A1 (en) 1978-05-10 1979-05-09 MACROLID ANTIBIOTICS, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE ANTIBIOTICS
DE2954218A DE2954218C2 (en) 1978-05-10 1979-05-09 Macrolide antibiotics and pharmaceutical preparations containing these antibiotics
IT22536/79A IT1113372B (en) 1978-05-10 1979-05-10 PROCEDURE TO PRODUCE ANTIBIOTIC SUBSTANCES AND THEIR ANTIBIOTICS SO OBTAINED
US06/037,846 US4291021A (en) 1978-05-10 1979-05-10 Novel macrolide antibiotics and preparation thereof
FR7911883A FR2425444A1 (en) 1978-05-10 1979-05-10 NEW MACROLIDE-TYPE ANTIBIOTICS, THEIR PREPARATION AND THERAPEUTIC USE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2478879A JPS55115900A (en) 1979-03-02 1979-03-02 Novel macrolide antibiotic substance a11725 3 and its preparation

Publications (2)

Publication Number Publication Date
JPS55115900A true JPS55115900A (en) 1980-09-06
JPS6118557B2 JPS6118557B2 (en) 1986-05-13

Family

ID=12147915

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2478879A Granted JPS55115900A (en) 1978-05-10 1979-03-02 Novel macrolide antibiotic substance a11725 3 and its preparation

Country Status (1)

Country Link
JP (1) JPS55115900A (en)

Also Published As

Publication number Publication date
JPS6118557B2 (en) 1986-05-13

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