JPS55115845A - Preparation of isoprenoid derivative - Google Patents

Preparation of isoprenoid derivative

Info

Publication number
JPS55115845A
JPS55115845A JP2195379A JP2195379A JPS55115845A JP S55115845 A JPS55115845 A JP S55115845A JP 2195379 A JP2195379 A JP 2195379A JP 2195379 A JP2195379 A JP 2195379A JP S55115845 A JPS55115845 A JP S55115845A
Authority
JP
Japan
Prior art keywords
compound
formula
nitroalkane
enzyme
acid catalyst
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2195379A
Other languages
Japanese (ja)
Inventor
Nobuyuki Fukazawa
Atsushi Kojima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP2195379A priority Critical patent/JPS55115845A/en
Publication of JPS55115845A publication Critical patent/JPS55115845A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the title compound, co-enzyme Q10, etc. useful as a drug for heart diseases, by oxidizing a condensate, prepared from a hydroquinone derivative and (iso)prenyl alcohol in the presence of a nitroalkane and a Lewis acid catalyst.
CONSTITUTION: A compound of formula I (R1 is H or lower alkyl group; R2 and R3 are lower alkoxy groups, or may form a naphthalene ring) is condensed with a compound of formula II or III (X is OH, halogen, acyloxy, or allylsulfonyloxy group; n is an integer 1W9) in the presence of a Lewis acid catalyst and a nitroalkane, e.g. nitromethane, etc. to form a compound of formula IV, which is oxidized to give the objective compound, e.g. vitamin K, Plastoquinone, or co-enzyme Q, of formula V. The method provides the product readily in a high yield commercially with suppressed side reactions without inhibiting the main reaction.
COPYRIGHT: (C)1980,JPO&Japio
JP2195379A 1979-02-28 1979-02-28 Preparation of isoprenoid derivative Pending JPS55115845A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2195379A JPS55115845A (en) 1979-02-28 1979-02-28 Preparation of isoprenoid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2195379A JPS55115845A (en) 1979-02-28 1979-02-28 Preparation of isoprenoid derivative

Publications (1)

Publication Number Publication Date
JPS55115845A true JPS55115845A (en) 1980-09-06

Family

ID=12069419

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2195379A Pending JPS55115845A (en) 1979-02-28 1979-02-28 Preparation of isoprenoid derivative

Country Status (1)

Country Link
JP (1) JPS55115845A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0243849A2 (en) * 1986-04-23 1987-11-04 Yeda Research And Development Company Limited Process for the production of polyprenoid type compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0243849A2 (en) * 1986-04-23 1987-11-04 Yeda Research And Development Company Limited Process for the production of polyprenoid type compounds

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