JPS55115845A - Preparation of isoprenoid derivative - Google Patents
Preparation of isoprenoid derivativeInfo
- Publication number
- JPS55115845A JPS55115845A JP2195379A JP2195379A JPS55115845A JP S55115845 A JPS55115845 A JP S55115845A JP 2195379 A JP2195379 A JP 2195379A JP 2195379 A JP2195379 A JP 2195379A JP S55115845 A JPS55115845 A JP S55115845A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- nitroalkane
- enzyme
- acid catalyst
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the title compound, co-enzyme Q10, etc. useful as a drug for heart diseases, by oxidizing a condensate, prepared from a hydroquinone derivative and (iso)prenyl alcohol in the presence of a nitroalkane and a Lewis acid catalyst.
CONSTITUTION: A compound of formula I (R1 is H or lower alkyl group; R2 and R3 are lower alkoxy groups, or may form a naphthalene ring) is condensed with a compound of formula II or III (X is OH, halogen, acyloxy, or allylsulfonyloxy group; n is an integer 1W9) in the presence of a Lewis acid catalyst and a nitroalkane, e.g. nitromethane, etc. to form a compound of formula IV, which is oxidized to give the objective compound, e.g. vitamin K, Plastoquinone, or co-enzyme Q, of formula V. The method provides the product readily in a high yield commercially with suppressed side reactions without inhibiting the main reaction.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2195379A JPS55115845A (en) | 1979-02-28 | 1979-02-28 | Preparation of isoprenoid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2195379A JPS55115845A (en) | 1979-02-28 | 1979-02-28 | Preparation of isoprenoid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55115845A true JPS55115845A (en) | 1980-09-06 |
Family
ID=12069419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2195379A Pending JPS55115845A (en) | 1979-02-28 | 1979-02-28 | Preparation of isoprenoid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55115845A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0243849A2 (en) * | 1986-04-23 | 1987-11-04 | Yeda Research And Development Company Limited | Process for the production of polyprenoid type compounds |
-
1979
- 1979-02-28 JP JP2195379A patent/JPS55115845A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0243849A2 (en) * | 1986-04-23 | 1987-11-04 | Yeda Research And Development Company Limited | Process for the production of polyprenoid type compounds |
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