JPS5492962A - Thiohydantoin compound - Google Patents
Thiohydantoin compoundInfo
- Publication number
- JPS5492962A JPS5492962A JP14855478A JP14855478A JPS5492962A JP S5492962 A JPS5492962 A JP S5492962A JP 14855478 A JP14855478 A JP 14855478A JP 14855478 A JP14855478 A JP 14855478A JP S5492962 A JPS5492962 A JP S5492962A
- Authority
- JP
- Japan
- Prior art keywords
- thiohydantoin compound
- thiohydantoin
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5009377 | 1977-12-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5492962A true JPS5492962A (en) | 1979-07-23 |
Family
ID=10454631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14855478A Pending JPS5492962A (en) | 1977-12-01 | 1978-11-30 | Thiohydantoin compound |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0002259B1 (ja) |
JP (1) | JPS5492962A (ja) |
AU (1) | AU531493B2 (ja) |
DE (1) | DE2862445D1 (ja) |
DK (1) | DK543178A (ja) |
ZA (1) | ZA786739B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04297461A (ja) * | 1991-03-27 | 1992-10-21 | Otsuka Pharmaceut Factory Inc | 2−チオヒダントイン誘導体 |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59065A0 (en) * | 1979-01-18 | 1980-05-30 | Beecham Group Ltd | Hydantoin derivatives,their preparation pharmaceutical compositons containing them |
EP0023083A1 (en) * | 1979-06-27 | 1981-01-28 | Beecham Group Plc | Oxodiazole derivatives, processes for their production and pharmaceutical composition containing them |
US5137904A (en) * | 1989-05-30 | 1992-08-11 | G. D. Searle & Co. | Thiohydantoin inhibitors of collagen-induced and ADP-induced platelet aggregation |
IL102548A (en) * | 1991-08-02 | 1998-08-16 | Medivir Ab | Use of painting derivatives in the preparation of drugs for VIH inhibition and treatment of SDIA and new compounds |
US5593993A (en) * | 1991-08-02 | 1997-01-14 | Medivir Ab | Method for inhibition of HIV related viruses |
FR2845384B1 (fr) * | 2002-10-04 | 2004-12-31 | Fournier Lab Sa | Composes derives de la 2-thiohydantoine et leur utilisation en therapeutique |
FR2845383B1 (fr) * | 2002-10-04 | 2004-12-31 | Fournier Lab Sa | Composes derives de la 2-thiohydantoine et leur utilisation en therapeutique |
FR2845385B1 (fr) * | 2002-10-04 | 2004-12-31 | Fournier Lab Sa | Composes derives de la 2-thiohydantoine et leur utilisation en therapeutique |
AU2003279442A1 (en) * | 2002-10-04 | 2004-04-23 | Laboratoires Fournier S.A. | 2-thiohydantoine derivative compounds and use thereof for the treatment of diabetes |
EP2299266A1 (en) | 2003-12-19 | 2011-03-23 | The Regents of the University of California | Methods and materials for assessing prostate cancer therapies |
NZ550102A (en) | 2004-02-24 | 2010-10-29 | Univ California | Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives) |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
ES2863798T3 (es) | 2006-03-27 | 2021-10-11 | Univ California | Modulador del receptor de andrógenos para el tratamiento del cáncer de próstata y enfermedades asociadas con el receptor de andrógenos |
RU2449993C2 (ru) | 2006-03-29 | 2012-05-10 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Диарилтиогидантоиновые соединения |
CA2703635C (en) | 2007-10-26 | 2017-06-27 | Michael E. Jung | Diarylhydantoin compounds as androgen receptor modulators |
EP3124481B1 (en) | 2010-02-16 | 2018-03-28 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
KR20210013342A (ko) | 2012-09-26 | 2021-02-03 | 아라곤 파마슈티컬스, 인코포레이티드 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
JOP20200076A1 (ar) | 2017-10-16 | 2020-04-30 | Aragon Pharmaceuticals Inc | مضادات أندروجين لعلاج سرطان البروستاتا غير النقيلي المقاوم للاستئصال |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB817745A (en) * | 1956-12-14 | 1959-08-06 | Ici Ltd | 2-thiohydantoins |
DE2138225A1 (de) * | 1971-07-30 | 1973-02-08 | Diamalt Ag | Hydantoinderivate |
DE2539730A1 (de) * | 1975-09-06 | 1977-03-17 | Bayer Ag | Mit carbonsaeureestergruppen modifizierte hydantoine |
FI71930C (fi) * | 1976-06-03 | 1987-03-09 | Wellcome Found | Foerfarande foer framstaellning av 1,5-disubstituerad hydantoin med aggregation av blodkroppar foerhindrande verkan. |
AU515174B2 (en) * | 1976-06-03 | 1981-03-19 | Wellcome Foundation Limited, The | Hydantoin derivatives |
IL53559A0 (en) * | 1976-12-18 | 1978-03-10 | Beecham Group Ltd | Novel prostaglandin analogues their preparation and pharmaceutical compositions containing them |
GB1598662A (en) * | 1976-12-18 | 1981-09-23 | Beecham Group Ltd | 10,12-diazoprostaglandins |
-
1978
- 1978-11-30 DK DK543178A patent/DK543178A/da not_active Application Discontinuation
- 1978-11-30 JP JP14855478A patent/JPS5492962A/ja active Pending
- 1978-11-30 ZA ZA786739A patent/ZA786739B/xx unknown
- 1978-11-30 AU AU42087/78A patent/AU531493B2/en not_active Expired
- 1978-12-01 DE DE7878101491T patent/DE2862445D1/de not_active Expired
- 1978-12-01 EP EP78101491A patent/EP0002259B1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04297461A (ja) * | 1991-03-27 | 1992-10-21 | Otsuka Pharmaceut Factory Inc | 2−チオヒダントイン誘導体 |
Also Published As
Publication number | Publication date |
---|---|
EP0002259A2 (en) | 1979-06-13 |
AU531493B2 (en) | 1983-08-25 |
AU4208778A (en) | 1979-06-07 |
DE2862445D1 (en) | 1984-11-08 |
EP0002259B1 (en) | 1984-10-03 |
EP0002259A3 (en) | 1979-06-27 |
DK543178A (da) | 1979-06-02 |
ZA786739B (en) | 1980-07-30 |
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