JPS5481285A - Propionamide derivative and its preparation - Google Patents
Propionamide derivative and its preparationInfo
- Publication number
- JPS5481285A JPS5481285A JP14880777A JP14880777A JPS5481285A JP S5481285 A JPS5481285 A JP S5481285A JP 14880777 A JP14880777 A JP 14880777A JP 14880777 A JP14880777 A JP 14880777A JP S5481285 A JPS5481285 A JP S5481285A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- propionamide
- formula
- derivative
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A propionamide derivative of formula I: (A is O or S; X is N or CH).
EXAMPLE: 2-[10,11-Dihydrodibenzo [b,f] thiepin-2-yl]-propionamide.
USE: Anti-inflammatory drugs.
PROCESS: A compound of formula III or its reactive derivative is reacted with NH3 in the presence of a condensing agent, e.g. dicyclohexylcarbodiimide, etc. in an inert solvent, e.g. methylene chloride, etc. to give the compound of formula I. An acid halide, obtained by reacting the compound of formula III with a halogenating agent, e.g. thionyl chloride, phosphorus pentachloride, or a mixed acid anhydride, obtained by reacting with ethyl chloroformate, etc. may be cited as the reactive derivative.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14880777A JPS5481285A (en) | 1977-12-13 | 1977-12-13 | Propionamide derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14880777A JPS5481285A (en) | 1977-12-13 | 1977-12-13 | Propionamide derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5481285A true JPS5481285A (en) | 1979-06-28 |
Family
ID=15461139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14880777A Pending JPS5481285A (en) | 1977-12-13 | 1977-12-13 | Propionamide derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5481285A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6021156A (en) * | 1983-07-15 | 1985-02-02 | Nisshin Steel Co Ltd | Continuous casting device for broad and thin plate |
-
1977
- 1977-12-13 JP JP14880777A patent/JPS5481285A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6021156A (en) * | 1983-07-15 | 1985-02-02 | Nisshin Steel Co Ltd | Continuous casting device for broad and thin plate |
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