JPS5476895A - Preparation of antibiotic substance c-15003p-2 - Google Patents

Preparation of antibiotic substance c-15003p-2

Info

Publication number
JPS5476895A
JPS5476895A JP14183777A JP14183777A JPS5476895A JP S5476895 A JPS5476895 A JP S5476895A JP 14183777 A JP14183777 A JP 14183777A JP 14183777 A JP14183777 A JP 14183777A JP S5476895 A JPS5476895 A JP S5476895A
Authority
JP
Japan
Prior art keywords
antibiotic substance
analogue
substance
medium containing
bacteria belonging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14183777A
Other languages
Japanese (ja)
Other versions
JPS6016237B2 (en
Inventor
Eiji Higashide
Kazunori Hatano
Mitsuko Asai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP14183777A priority Critical patent/JPS6016237B2/en
Publication of JPS5476895A publication Critical patent/JPS5476895A/en
Publication of JPS6016237B2 publication Critical patent/JPS6016237B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To prepare the title substance in high efficiency and nearly exclusively, by culturing bacteria belonging to Nocardia genus in a medium containing a specific material.
CONSTITUTION: Antibiotic substance C-15003-producing bacteria belonging to Nocardia genus, e.g. Actinomyces No. C-15003 strain, are cultured in a medium containing 0.01-0.1 W/V% of at least one compound selected from a propionyl CoA precursor (e.g. α-C4-amino acid such as threonine, homoserine, etc., C4 ketocarboxylic acid such as α-ketobutylate, etc.), propionic acid, a leucine-analogue (e.g. norleucine) and a valine-analogue (e.g. norvaline). Antibiotic substance C-15003P-2 is specifically produced and accumulated in the medium.
COPYRIGHT: (C)1979,JPO&Japio
JP14183777A 1977-11-25 1977-11-25 Production method of antibiotic C-15003 P-2 Expired JPS6016237B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14183777A JPS6016237B2 (en) 1977-11-25 1977-11-25 Production method of antibiotic C-15003 P-2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14183777A JPS6016237B2 (en) 1977-11-25 1977-11-25 Production method of antibiotic C-15003 P-2

Publications (2)

Publication Number Publication Date
JPS5476895A true JPS5476895A (en) 1979-06-19
JPS6016237B2 JPS6016237B2 (en) 1985-04-24

Family

ID=15301285

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14183777A Expired JPS6016237B2 (en) 1977-11-25 1977-11-25 Production method of antibiotic C-15003 P-2

Country Status (1)

Country Link
JP (1) JPS6016237B2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0267824A (en) * 1988-09-01 1990-03-07 Nec Ic Microcomput Syst Ltd Key input device

Also Published As

Publication number Publication date
JPS6016237B2 (en) 1985-04-24

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