JPS5441386A - Preparation of l-proline by fermentation - Google Patents

Preparation of l-proline by fermentation

Info

Publication number
JPS5441386A
JPS5441386A JP10473777A JP10473777A JPS5441386A JP S5441386 A JPS5441386 A JP S5441386A JP 10473777 A JP10473777 A JP 10473777A JP 10473777 A JP10473777 A JP 10473777A JP S5441386 A JPS5441386 A JP S5441386A
Authority
JP
Japan
Prior art keywords
corynebacterium
proline
acetophilum
fermentation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10473777A
Other languages
Japanese (ja)
Inventor
Keiichi Inuzuka
Yoshitada Takazawa
Susumu Tomohiro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP10473777A priority Critical patent/JPS5441386A/en
Publication of JPS5441386A publication Critical patent/JPS5441386A/en
Pending legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare L-proline useful as a pharmaceutical and additive of feeds, in high productivity, by culturing a variant of bacterial belonging to Corynebacterium genus.
CONSTITUTION: Bacteria belonging to Corynebacterium genus, and demanding homoserine, methionine, and threonine, e.g. Corynebacterium acetophilum KOL- 46(FERM-P No.4045), obtained by treating Corynebacterium acetophilum KY7761 (NRRL-B-3761) with N-methyl-N'-nitro-N-nitrosoguanidine, are aerobically cultivated under agitation suually at 20W40°C and pref. pH5W8 for 2W5 days, and the titled compound is separated from the cultivation medium.
COPYRIGHT: (C)1979,JPO&Japio
JP10473777A 1977-09-02 1977-09-02 Preparation of l-proline by fermentation Pending JPS5441386A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10473777A JPS5441386A (en) 1977-09-02 1977-09-02 Preparation of l-proline by fermentation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10473777A JPS5441386A (en) 1977-09-02 1977-09-02 Preparation of l-proline by fermentation

Publications (1)

Publication Number Publication Date
JPS5441386A true JPS5441386A (en) 1979-04-02

Family

ID=14388800

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10473777A Pending JPS5441386A (en) 1977-09-02 1977-09-02 Preparation of l-proline by fermentation

Country Status (1)

Country Link
JP (1) JPS5441386A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012144592A1 (en) * 2011-04-22 2012-10-26 アステラス製薬株式会社 Solid pharmaceutical composition

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012144592A1 (en) * 2011-04-22 2012-10-26 アステラス製薬株式会社 Solid pharmaceutical composition
JPWO2012144592A1 (en) * 2011-04-22 2014-07-28 アステラス製薬株式会社 Solid pharmaceutical composition
JP6063379B2 (en) * 2011-04-22 2017-01-18 アステラス製薬株式会社 Solid pharmaceutical composition

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