JPS5441386A - Preparation of l-proline by fermentation - Google Patents
Preparation of l-proline by fermentationInfo
- Publication number
- JPS5441386A JPS5441386A JP10473777A JP10473777A JPS5441386A JP S5441386 A JPS5441386 A JP S5441386A JP 10473777 A JP10473777 A JP 10473777A JP 10473777 A JP10473777 A JP 10473777A JP S5441386 A JPS5441386 A JP S5441386A
- Authority
- JP
- Japan
- Prior art keywords
- corynebacterium
- proline
- acetophilum
- fermentation
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare L-proline useful as a pharmaceutical and additive of feeds, in high productivity, by culturing a variant of bacterial belonging to Corynebacterium genus.
CONSTITUTION: Bacteria belonging to Corynebacterium genus, and demanding homoserine, methionine, and threonine, e.g. Corynebacterium acetophilum KOL- 46(FERM-P No.4045), obtained by treating Corynebacterium acetophilum KY7761 (NRRL-B-3761) with N-methyl-N'-nitro-N-nitrosoguanidine, are aerobically cultivated under agitation suually at 20W40°C and pref. pH5W8 for 2W5 days, and the titled compound is separated from the cultivation medium.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10473777A JPS5441386A (en) | 1977-09-02 | 1977-09-02 | Preparation of l-proline by fermentation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10473777A JPS5441386A (en) | 1977-09-02 | 1977-09-02 | Preparation of l-proline by fermentation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5441386A true JPS5441386A (en) | 1979-04-02 |
Family
ID=14388800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10473777A Pending JPS5441386A (en) | 1977-09-02 | 1977-09-02 | Preparation of l-proline by fermentation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5441386A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012144592A1 (en) * | 2011-04-22 | 2012-10-26 | アステラス製薬株式会社 | Solid pharmaceutical composition |
-
1977
- 1977-09-02 JP JP10473777A patent/JPS5441386A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012144592A1 (en) * | 2011-04-22 | 2012-10-26 | アステラス製薬株式会社 | Solid pharmaceutical composition |
JPWO2012144592A1 (en) * | 2011-04-22 | 2014-07-28 | アステラス製薬株式会社 | Solid pharmaceutical composition |
JP6063379B2 (en) * | 2011-04-22 | 2017-01-18 | アステラス製薬株式会社 | Solid pharmaceutical composition |
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