JPS5466674A - Novel phenylacetic acid derivative - Google Patents

Novel phenylacetic acid derivative

Info

Publication number
JPS5466674A
JPS5466674A JP13494077A JP13494077A JPS5466674A JP S5466674 A JPS5466674 A JP S5466674A JP 13494077 A JP13494077 A JP 13494077A JP 13494077 A JP13494077 A JP 13494077A JP S5466674 A JPS5466674 A JP S5466674A
Authority
JP
Japan
Prior art keywords
acid derivative
phenylacetic acid
halogen
pyridyl
novel phenylacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13494077A
Other languages
Japanese (ja)
Other versions
JPS6051475B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Satoru Miyata
Yoichi Nakajima
Kazuyoshi Noguchi
Masayoshi Tsuji
Tetsuo Aoki
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP13494077A priority Critical patent/JPS6051475B2/en
Publication of JPS5466674A publication Critical patent/JPS5466674A/en
Publication of JPS6051475B2 publication Critical patent/JPS6051475B2/en
Expired legal-status Critical Current

Links

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  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A phenylacetic acid derivative of formula I (R1 is lower alkyl, aryl, cycloalkykl, aralkyl, pyridyl, substituted pyridyl; Y is H, halogen; R2 is H, methyl, ethyl; Z is carboxyl, carbomoyl, cyano, lower alkoxycarbonyl).
EXAMPLE: 4-[2-(p-Chlorophenyl)thiazol-4-yl]phenylacetonitrile.
USE: Analgesic, antiphlogistic, antipyretic agent.
PROCESS: The compound I is prepared by reacting 1 mole of a compoond II (X is halogen) with (pref. 1-1.2 moles of) thioamide drivative III in an alcohol such as methanol, ethanol, propanol, etc., at 40-150°C.
COPYRIGHT: (C)1979,JPO&Japio
JP13494077A 1977-11-08 1977-11-08 Novel phenyl acetic acid derivative Expired JPS6051475B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13494077A JPS6051475B2 (en) 1977-11-08 1977-11-08 Novel phenyl acetic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13494077A JPS6051475B2 (en) 1977-11-08 1977-11-08 Novel phenyl acetic acid derivative

Publications (2)

Publication Number Publication Date
JPS5466674A true JPS5466674A (en) 1979-05-29
JPS6051475B2 JPS6051475B2 (en) 1985-11-14

Family

ID=15140102

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13494077A Expired JPS6051475B2 (en) 1977-11-08 1977-11-08 Novel phenyl acetic acid derivative

Country Status (1)

Country Link
JP (1) JPS6051475B2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011278A1 (en) * 1989-03-24 1990-10-04 The Green Cross Corporation Thiazole compounds and applications thereof
US5643932A (en) * 1990-11-30 1997-07-01 Otsuka Pharmaceutical Co., Ltd. Superoxide radical inhibitor
FR2921063A1 (en) * 2007-09-13 2009-03-20 Sod Conseils Rech Applic New 4-phenyl-1,3-azole compounds are cannabinoid receptor 2 modulators useful to treat or prevent cell proliferation disorders e.g. cancer, immune and autoimmune diseases, allergic diseases, inflammation, pain and eye disease
US8354439B2 (en) 1996-09-30 2013-01-15 Otsuka Pharmaceutical Co., Ltd. Agent for inhibition of cytokine production and agent for inhibition of cell adhesion

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62299777A (en) * 1986-06-20 1987-12-26 Akai Electric Co Ltd Method and jig for measuring magnetic permeability of soft magnetic thin film

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011278A1 (en) * 1989-03-24 1990-10-04 The Green Cross Corporation Thiazole compounds and applications thereof
US5643932A (en) * 1990-11-30 1997-07-01 Otsuka Pharmaceutical Co., Ltd. Superoxide radical inhibitor
US5677319A (en) * 1990-11-30 1997-10-14 Otsuka Pharmaceutical Co., Ltd. Superoxide radical inhibitor
US6080764A (en) * 1990-11-30 2000-06-27 Otsuka Pharmaceutical Co., Ltd. Superoxide radical inhibitor
USRE37556E1 (en) 1990-11-30 2002-02-19 Otsuka Pharmaceutical Co., Ltd. Superoxide radical inhibitor
US8354439B2 (en) 1996-09-30 2013-01-15 Otsuka Pharmaceutical Co., Ltd. Agent for inhibition of cytokine production and agent for inhibition of cell adhesion
FR2921063A1 (en) * 2007-09-13 2009-03-20 Sod Conseils Rech Applic New 4-phenyl-1,3-azole compounds are cannabinoid receptor 2 modulators useful to treat or prevent cell proliferation disorders e.g. cancer, immune and autoimmune diseases, allergic diseases, inflammation, pain and eye disease
WO2009071753A1 (en) * 2007-09-13 2009-06-11 Ipsen Pharma S.A.S. Cannabinoid receptor ligands

Also Published As

Publication number Publication date
JPS6051475B2 (en) 1985-11-14

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