JPS5466674A - Novel phenylacetic acid derivative - Google Patents
Novel phenylacetic acid derivativeInfo
- Publication number
- JPS5466674A JPS5466674A JP13494077A JP13494077A JPS5466674A JP S5466674 A JPS5466674 A JP S5466674A JP 13494077 A JP13494077 A JP 13494077A JP 13494077 A JP13494077 A JP 13494077A JP S5466674 A JPS5466674 A JP S5466674A
- Authority
- JP
- Japan
- Prior art keywords
- acid derivative
- phenylacetic acid
- halogen
- pyridyl
- novel phenylacetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A phenylacetic acid derivative of formula I (R1 is lower alkyl, aryl, cycloalkykl, aralkyl, pyridyl, substituted pyridyl; Y is H, halogen; R2 is H, methyl, ethyl; Z is carboxyl, carbomoyl, cyano, lower alkoxycarbonyl).
EXAMPLE: 4-[2-(p-Chlorophenyl)thiazol-4-yl]phenylacetonitrile.
USE: Analgesic, antiphlogistic, antipyretic agent.
PROCESS: The compound I is prepared by reacting 1 mole of a compoond II (X is halogen) with (pref. 1-1.2 moles of) thioamide drivative III in an alcohol such as methanol, ethanol, propanol, etc., at 40-150°C.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13494077A JPS6051475B2 (en) | 1977-11-08 | 1977-11-08 | Novel phenyl acetic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13494077A JPS6051475B2 (en) | 1977-11-08 | 1977-11-08 | Novel phenyl acetic acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5466674A true JPS5466674A (en) | 1979-05-29 |
JPS6051475B2 JPS6051475B2 (en) | 1985-11-14 |
Family
ID=15140102
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13494077A Expired JPS6051475B2 (en) | 1977-11-08 | 1977-11-08 | Novel phenyl acetic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6051475B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990011278A1 (en) * | 1989-03-24 | 1990-10-04 | The Green Cross Corporation | Thiazole compounds and applications thereof |
US5643932A (en) * | 1990-11-30 | 1997-07-01 | Otsuka Pharmaceutical Co., Ltd. | Superoxide radical inhibitor |
FR2921063A1 (en) * | 2007-09-13 | 2009-03-20 | Sod Conseils Rech Applic | New 4-phenyl-1,3-azole compounds are cannabinoid receptor 2 modulators useful to treat or prevent cell proliferation disorders e.g. cancer, immune and autoimmune diseases, allergic diseases, inflammation, pain and eye disease |
US8354439B2 (en) | 1996-09-30 | 2013-01-15 | Otsuka Pharmaceutical Co., Ltd. | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62299777A (en) * | 1986-06-20 | 1987-12-26 | Akai Electric Co Ltd | Method and jig for measuring magnetic permeability of soft magnetic thin film |
-
1977
- 1977-11-08 JP JP13494077A patent/JPS6051475B2/en not_active Expired
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990011278A1 (en) * | 1989-03-24 | 1990-10-04 | The Green Cross Corporation | Thiazole compounds and applications thereof |
US5643932A (en) * | 1990-11-30 | 1997-07-01 | Otsuka Pharmaceutical Co., Ltd. | Superoxide radical inhibitor |
US5677319A (en) * | 1990-11-30 | 1997-10-14 | Otsuka Pharmaceutical Co., Ltd. | Superoxide radical inhibitor |
US6080764A (en) * | 1990-11-30 | 2000-06-27 | Otsuka Pharmaceutical Co., Ltd. | Superoxide radical inhibitor |
USRE37556E1 (en) | 1990-11-30 | 2002-02-19 | Otsuka Pharmaceutical Co., Ltd. | Superoxide radical inhibitor |
US8354439B2 (en) | 1996-09-30 | 2013-01-15 | Otsuka Pharmaceutical Co., Ltd. | Agent for inhibition of cytokine production and agent for inhibition of cell adhesion |
FR2921063A1 (en) * | 2007-09-13 | 2009-03-20 | Sod Conseils Rech Applic | New 4-phenyl-1,3-azole compounds are cannabinoid receptor 2 modulators useful to treat or prevent cell proliferation disorders e.g. cancer, immune and autoimmune diseases, allergic diseases, inflammation, pain and eye disease |
WO2009071753A1 (en) * | 2007-09-13 | 2009-06-11 | Ipsen Pharma S.A.S. | Cannabinoid receptor ligands |
Also Published As
Publication number | Publication date |
---|---|
JPS6051475B2 (en) | 1985-11-14 |
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