JPS5466669A - Purification of 2- thiopheneacetic acid - Google Patents
Purification of 2- thiopheneacetic acidInfo
- Publication number
- JPS5466669A JPS5466669A JP13383977A JP13383977A JPS5466669A JP S5466669 A JPS5466669 A JP S5466669A JP 13383977 A JP13383977 A JP 13383977A JP 13383977 A JP13383977 A JP 13383977A JP S5466669 A JPS5466669 A JP S5466669A
- Authority
- JP
- Japan
- Prior art keywords
- pref
- thiopheneacetic acid
- mixture
- acid
- thiopheneacetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
PURPOSE: To prepare colorless, high purity title compound useful as an intermediate of cephalosporin antibiotic substance, easily and economically, by mixing crude 2-thiopheneacetic acid with water at specific temeprature and concentration, separating the mixture into two phases, and extracting the upper phase.
CONSTITUTION: A crude 2-thiopheneacetic acid containing colored impurities, is mixed to water to obtain a mixture containing 2-90 wt%, pref. 5-20 wt% of 2- thiophene-acetic acid. The mixture is left at rest at 20-100°C, pref. 30-80°C, and the mixture is separated into two phases; i.e. lower liquid phase containing 30-90 wt%, pref. 40-80 wt%, esp. pref. 50-70 wt% of 2-thiopheneacetic acid, and an upper liquid phase containing 2-20 wt%, pref. 5-15 wt%, esp. pref. 5-8 wt%, of 2-thiopheneacetic acid. High purity 2-thiopheneacetic acid is separated from the upper phase by conventional method such as extraction, etc.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13383977A JPS5466669A (en) | 1977-11-07 | 1977-11-07 | Purification of 2- thiopheneacetic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13383977A JPS5466669A (en) | 1977-11-07 | 1977-11-07 | Purification of 2- thiopheneacetic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5466669A true JPS5466669A (en) | 1979-05-29 |
| JPS5623429B2 JPS5623429B2 (en) | 1981-05-30 |
Family
ID=15114238
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13383977A Granted JPS5466669A (en) | 1977-11-07 | 1977-11-07 | Purification of 2- thiopheneacetic acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5466669A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61110132U (en) * | 1984-12-25 | 1986-07-12 |
-
1977
- 1977-11-07 JP JP13383977A patent/JPS5466669A/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5623429B2 (en) | 1981-05-30 |
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