JPS5463070A - 2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation - Google Patents

2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation

Info

Publication number
JPS5463070A
JPS5463070A JP12872277A JP12872277A JPS5463070A JP S5463070 A JPS5463070 A JP S5463070A JP 12872277 A JP12872277 A JP 12872277A JP 12872277 A JP12872277 A JP 12872277A JP S5463070 A JPS5463070 A JP S5463070A
Authority
JP
Japan
Prior art keywords
compound
methylpyrrole
nitroethyl
derivative
aroyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12872277A
Other languages
Japanese (ja)
Inventor
Tamotsu Fujisawa
Kunikazu Sakai
Akiko Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP12872277A priority Critical patent/JPS5463070A/en
Publication of JPS5463070A publication Critical patent/JPS5463070A/en
Pending legal-status Critical Current

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  • Pyrrole Compounds (AREA)

Abstract

NEW MATERIAL:2-(2-Nitroethyl)-methylpyrrole I [R is H, (substituted) aroyl], and its derivative.
USE: An intermediate for the economical and industrial production of (1-methyl-5- aroylpyrroly1-2)acetic acid III which is a strong antiphlogistic agent.
PROCESS: 2-(2-Nitroethyl)-1-methylpyrrole I' (which is one of the compound I) is prepared by reacting industrially available methylpyrrole II with 1-nitro-2-aclyloxyethane. Aroylation of the compound I' gives 5-aroyl compound I" (Ar is (substituted) aryl) which is also one of the compound I. The antipholgistic compound III is obtained by reacting the compound I" with an acid anhydride, followed by hydrolyzing the product with an alkali.
COPYRIGHT: (C)1979,JPO&Japio
JP12872277A 1977-10-28 1977-10-28 2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation Pending JPS5463070A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12872277A JPS5463070A (en) 1977-10-28 1977-10-28 2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12872277A JPS5463070A (en) 1977-10-28 1977-10-28 2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation

Publications (1)

Publication Number Publication Date
JPS5463070A true JPS5463070A (en) 1979-05-21

Family

ID=14991807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12872277A Pending JPS5463070A (en) 1977-10-28 1977-10-28 2-(2-nitroethyl)-1-methylpyrrole, its derivative, and their preparation

Country Status (1)

Country Link
JP (1) JPS5463070A (en)

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