JPS5441883A - Thiamine derivative and its preparation - Google Patents
Thiamine derivative and its preparationInfo
- Publication number
- JPS5441883A JPS5441883A JP10694377A JP10694377A JPS5441883A JP S5441883 A JPS5441883 A JP S5441883A JP 10694377 A JP10694377 A JP 10694377A JP 10694377 A JP10694377 A JP 10694377A JP S5441883 A JPS5441883 A JP S5441883A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- preparation
- formulai
- alkali metal
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003544 thiamines Chemical class 0.000 title abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 108010064733 Angiotensins Proteins 0.000 abstract 1
- 102000015427 Angiotensins Human genes 0.000 abstract 1
- 101800004538 Bradykinin Proteins 0.000 abstract 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 102100035792 Kininogen-1 Human genes 0.000 abstract 1
- 229930003451 Vitamin B1 Natural products 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 229960003495 thiamine Drugs 0.000 abstract 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
- 239000011691 vitamin B1 Substances 0.000 abstract 1
- 235000010374 vitamin B1 Nutrition 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10694377A JPS5441883A (en) | 1977-09-05 | 1977-09-05 | Thiamine derivative and its preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10694377A JPS5441883A (en) | 1977-09-05 | 1977-09-05 | Thiamine derivative and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5441883A true JPS5441883A (en) | 1979-04-03 |
| JPS6154798B2 JPS6154798B2 (enrdf_load_stackoverflow) | 1986-11-25 |
Family
ID=14446449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10694377A Granted JPS5441883A (en) | 1977-09-05 | 1977-09-05 | Thiamine derivative and its preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5441883A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005072738A1 (en) * | 2004-01-30 | 2005-08-11 | Faron Pharmaceuticals Oy | Compositions useful especially for treatment or prevention of metabolic syndrome |
-
1977
- 1977-09-05 JP JP10694377A patent/JPS5441883A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005072738A1 (en) * | 2004-01-30 | 2005-08-11 | Faron Pharmaceuticals Oy | Compositions useful especially for treatment or prevention of metabolic syndrome |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6154798B2 (enrdf_load_stackoverflow) | 1986-11-25 |
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