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Teijin Ltd
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Teijin Ltd
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Application filed by Teijin LtdfiledCriticalTeijin Ltd
Priority to JP6718478ApriorityCriticalpatent/JPS54160337A/en
Publication of JPS54160337ApublicationCriticalpatent/JPS54160337A/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
NEW MATERIAL:A cinnamic acid derivative of formula I: (R1 is monofunctional substituent; R2 and R3 are lower alkyl groups; n is 0, 1, or 2, R1 is H when n is 0; two R1's may form a ring when n is 2).
USE: Intermediates for the synthesis of analgesics, antithrombotics, antitussives, and hypotensives.
PROCESS: An optically active or inactive diester of formula II is heated in the presence of formic acid or formalin to give the objective compound of formula I.