JPS54151132A - Compound having antibiotic activity - Google Patents

Compound having antibiotic activity

Info

Publication number
JPS54151132A
JPS54151132A JP5941878A JP5941878A JPS54151132A JP S54151132 A JPS54151132 A JP S54151132A JP 5941878 A JP5941878 A JP 5941878A JP 5941878 A JP5941878 A JP 5941878A JP S54151132 A JPS54151132 A JP S54151132A
Authority
JP
Japan
Prior art keywords
residue
compound
aryl
daily
activity against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5941878A
Other languages
Japanese (ja)
Inventor
Tomohiko Munakata
Shinko Hosoya
Katsuyoshi Iimori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP5941878A priority Critical patent/JPS54151132A/en
Publication of JPS54151132A publication Critical patent/JPS54151132A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: A monic acid derivative that has strong antibacterial activity against gram-positive bacteria, and also penicillin or macroride-resisting bacteria.
CONSTITUTION: A compound of formula I (R1 is H, aryl; R2 is substd. or unsubstd. aryl, aralkyl, amino substituted with heterocyclic group, ureido, residue of carbamate ester, residue of amino acid, residue of dipeptide or its ester) as N-carbamoylmethyl monate, shows antibacterial activity against Staphylococcus aureus and Streptococcus numonie, which are gram-positive. The dose is 50W 2500 mg daily when orally given, 100W300 mg daily when nonorally given to general adults. It also can be used as a cream or paste containing 0.01W0.1% of the same.
COPYRIGHT: (C)1979,JPO&Japio
JP5941878A 1978-05-17 1978-05-17 Compound having antibiotic activity Pending JPS54151132A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5941878A JPS54151132A (en) 1978-05-17 1978-05-17 Compound having antibiotic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5941878A JPS54151132A (en) 1978-05-17 1978-05-17 Compound having antibiotic activity

Publications (1)

Publication Number Publication Date
JPS54151132A true JPS54151132A (en) 1979-11-28

Family

ID=13112690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5941878A Pending JPS54151132A (en) 1978-05-17 1978-05-17 Compound having antibiotic activity

Country Status (1)

Country Link
JP (1) JPS54151132A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0055616A1 (en) * 1980-12-31 1982-07-07 Beecham Group Plc Antibacterial compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0055616A1 (en) * 1980-12-31 1982-07-07 Beecham Group Plc Antibacterial compounds

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