JPS54141748A - Preparation of o-trifluoromethylbenzoic acid - Google Patents
Preparation of o-trifluoromethylbenzoic acidInfo
- Publication number
- JPS54141748A JPS54141748A JP4786978A JP4786978A JPS54141748A JP S54141748 A JPS54141748 A JP S54141748A JP 4786978 A JP4786978 A JP 4786978A JP 4786978 A JP4786978 A JP 4786978A JP S54141748 A JPS54141748 A JP S54141748A
- Authority
- JP
- Japan
- Prior art keywords
- pref
- chloro
- alkyl bromide
- benzotrifluoride
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare the title compound useful as an intermediate of pesticides, etc., economically, in high yield, by carbonating a compound obtained by reacting O-chloro-benzotrifluoride with Mg in the presence of a lower alkyl bromide.
CONSTITUTION: O-Chloro-benzotrifluoride is made to react with Mg in the presence of a 2W4C alkyl bromide, pref. isopropyl bromide, in a solvent such as tetrahydro- furan, at 20W120°C, pref. 50W60°C, and the reaction product is carbonated with a carbonating reagent (e.g. CO2, dry ice) to afford the objective O-trifluoro-methylbenzoic acid. The molar ratio of lower alkyl bromide to O-chloro-bebzotrifluoride is more than 1, and that of Mg to the sum of the above two starting materials is pref. more than 1.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4786978A JPS54141748A (en) | 1978-04-24 | 1978-04-24 | Preparation of o-trifluoromethylbenzoic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4786978A JPS54141748A (en) | 1978-04-24 | 1978-04-24 | Preparation of o-trifluoromethylbenzoic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54141748A true JPS54141748A (en) | 1979-11-05 |
JPS625137B2 JPS625137B2 (en) | 1987-02-03 |
Family
ID=12787373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4786978A Granted JPS54141748A (en) | 1978-04-24 | 1978-04-24 | Preparation of o-trifluoromethylbenzoic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54141748A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0491326A2 (en) * | 1990-12-17 | 1992-06-24 | ISTITUTO GUIDO DONEGANI S.p.A. | Process for the functionalization of trifluoromethylbenzenes |
JP2006265133A (en) * | 2005-03-23 | 2006-10-05 | Central Glass Co Ltd | Method for producing 4-methyl-3-trifluoromethylbenzoic acid |
-
1978
- 1978-04-24 JP JP4786978A patent/JPS54141748A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0491326A2 (en) * | 1990-12-17 | 1992-06-24 | ISTITUTO GUIDO DONEGANI S.p.A. | Process for the functionalization of trifluoromethylbenzenes |
EP0491326A3 (en) * | 1990-12-17 | 1992-11-04 | Istituto Guido Donegani S.P.A. | Process for the functionalization of trifluoromethylbenzenes |
JP2006265133A (en) * | 2005-03-23 | 2006-10-05 | Central Glass Co Ltd | Method for producing 4-methyl-3-trifluoromethylbenzoic acid |
Also Published As
Publication number | Publication date |
---|---|
JPS625137B2 (en) | 1987-02-03 |
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