JPS5215811A - Eye inserting substance and its preparation for eye drying diseases - Google Patents

Eye inserting substance and its preparation for eye drying diseases

Info

Publication number
JPS5215811A
JPS5215811A JP51089755A JP8975576A JPS5215811A JP S5215811 A JPS5215811 A JP S5215811A JP 51089755 A JP51089755 A JP 51089755A JP 8975576 A JP8975576 A JP 8975576A JP S5215811 A JPS5215811 A JP S5215811A
Authority
JP
Japan
Prior art keywords
eye
diseases
preparation
drying
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51089755A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6122975B2 (de
Inventor
Emu Katsutsu Aabuingu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5215811A publication Critical patent/JPS5215811A/ja
Publication of JPS6122975B2 publication Critical patent/JPS6122975B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP51089755A 1975-07-29 1976-07-29 Eye inserting substance and its preparation for eye drying diseases Granted JPS5215811A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60016875A 1975-07-29 1975-07-29

Publications (2)

Publication Number Publication Date
JPS5215811A true JPS5215811A (en) 1977-02-05
JPS6122975B2 JPS6122975B2 (de) 1986-06-03

Family

ID=24402570

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51089755A Granted JPS5215811A (en) 1975-07-29 1976-07-29 Eye inserting substance and its preparation for eye drying diseases

Country Status (16)

Country Link
US (1) US4343787A (de)
JP (1) JPS5215811A (de)
AU (1) AU509140B2 (de)
BE (1) BE844544A (de)
BR (1) BR7604876A (de)
CH (1) CH631891A5 (de)
CY (1) CY1137A (de)
DE (1) DE2633988C2 (de)
ES (3) ES450002A1 (de)
FR (1) FR2319375A1 (de)
GB (1) GB1543189A (de)
HK (1) HK282A (de)
IT (1) IT1062653B (de)
NL (1) NL188266C (de)
PT (1) PT65389B (de)
SE (1) SE431508B (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54145207A (en) * 1978-04-30 1979-11-13 Agency Of Ind Science & Technol High viscosity eye lotion
JPS58214128A (ja) * 1982-04-29 1983-12-13 チバ‐ガイギー　アクチエンゲゼルシヤフト アニ−ル処理ポリビニルアルコ−ルコンタクトレンズおよびその製法
WO2007013590A1 (ja) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. 固形組成物を用いた後眼部組織への非侵襲性ドラッグデリバリーシステム
JP2011037891A (ja) * 2002-09-30 2011-02-24 Mark A Babizhayev 薬剤組成物の製造のための水性眼科用組成物の使用、及び水性眼科用組成物

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US4436730A (en) 1979-06-25 1984-03-13 Polymer Technology Corporation Ionic opthalmic cellulose polymer solutions
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
EP0108661A1 (de) * 1982-10-04 1984-05-16 Merck & Co. Inc. Beständige Hydroxypropyl-Cellulose-Augeneinlagen und Verfahren zu ihrer Sterilisierung
US4565198A (en) * 1983-12-27 1986-01-21 Barnes-Hind, Inc. Method for altering the curvature of the cornea
US4660546A (en) * 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5209927A (en) * 1985-01-23 1993-05-11 Alcon Laboratories, Inc. Ophthalmic solution
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US5229128A (en) * 1986-06-11 1993-07-20 Haddad Heskel M Drug delivery ophthalmic insert and method of preparing same
US5989579A (en) * 1986-10-02 1999-11-23 Escalon Medical Corp. Ocular insert with anchoring protrusions
US5322691A (en) * 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
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US5075104A (en) * 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
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US5631004A (en) * 1993-09-30 1997-05-20 Alcon Laboratories, Inc. Use of sustained release antibiotic compositions in ophthalmic surgical procedures
TW274516B (de) * 1993-11-12 1996-04-21 Ciba Geigy Ag
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5472436A (en) * 1994-07-26 1995-12-05 Fremstad; Daria A. Ocular appliance for delivering medication
US5516808A (en) * 1994-10-27 1996-05-14 Sawaya; Assad S. Topical cellulose pharmaceutical formulation
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
DE19508029C2 (de) * 1995-03-07 1997-10-09 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation von ophthalmischen Arzneistoffen und Verfahren zur Herstellung derselben
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
US6193991B1 (en) * 1997-10-29 2001-02-27 Atul J. Shukla Biodegradable delivery systems of biologically active substances
WO2000051619A1 (en) 1999-03-01 2000-09-08 Vista Scientific Llc Mucin containing ophthalmic preparations
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US7404825B2 (en) * 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
EP2316394B1 (de) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoirvorrichtung für die intraokulare Arzneimittelabgabe
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US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
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CA2839928C (en) * 2003-06-13 2016-10-04 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US7914803B2 (en) 2003-06-13 2011-03-29 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of three polymers
WO2005018608A1 (ja) * 2003-08-20 2005-03-03 Santen Pharmaceutical Co., Ltd. 微粒子テノン嚢下投与ドラッグデリバリーシステム
JP4869930B2 (ja) * 2003-08-26 2012-02-08 ヴィスタ サイエンティフィック エルエルシー 眼科薬物供給装置
US7117870B2 (en) * 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
US20060020253A1 (en) * 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US20060067978A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly(vinyl alcohol) drug delivery devices
US20060068012A1 (en) * 2004-09-29 2006-03-30 Bausch & Lomb Incorporated Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control
US20070264338A1 (en) * 2006-05-12 2007-11-15 Shah Devang T Base-stabilized polyorthoester formulations
US20070265329A1 (en) * 2006-05-12 2007-11-15 Devang Shah T Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
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BE1030504B1 (fr) 2022-05-06 2023-12-04 Eyed Pharma Insert composite pour le traitement de la sécheresse oculaire
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US3767788A (en) * 1970-06-08 1973-10-23 Burton Parsons Chemicals Inc Ophthalmic solution
SE352811B (de) * 1971-06-04 1973-01-15 Pharmacia Ab
US3845201A (en) * 1972-04-24 1974-10-29 S Loucas Solid state ophthalmic medication delivery method
SE375007B (de) * 1972-11-30 1975-04-07 Pharmacia Ab
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3911098A (en) * 1974-02-11 1975-10-07 American Cyanamid Co Medicament carrier

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54145207A (en) * 1978-04-30 1979-11-13 Agency Of Ind Science & Technol High viscosity eye lotion
JPS5648484B2 (de) * 1978-04-30 1981-11-16
JPS58214128A (ja) * 1982-04-29 1983-12-13 チバ‐ガイギー　アクチエンゲゼルシヤフト アニ−ル処理ポリビニルアルコ−ルコンタクトレンズおよびその製法
JPH0352842B2 (de) * 1982-04-29 1991-08-13 Ciba Geigy
JP2011037891A (ja) * 2002-09-30 2011-02-24 Mark A Babizhayev 薬剤組成物の製造のための水性眼科用組成物の使用、及び水性眼科用組成物
JP2011037892A (ja) * 2002-09-30 2011-02-24 Mark A Babizhayev 治療手段
WO2007013590A1 (ja) * 2005-07-29 2007-02-01 Santen Pharmaceutical Co., Ltd. 固形組成物を用いた後眼部組織への非侵襲性ドラッグデリバリーシステム

Also Published As

Publication number Publication date
CY1137A (en) 1982-05-07
AU1607776A (en) 1978-01-26
NL7607704A (nl) 1977-02-01
SE7608036L (sv) 1977-01-30
HK282A (en) 1982-01-15
PT65389A (en) 1976-08-01
NL188266B (nl) 1991-12-16
ES461216A1 (es) 1978-05-01
JPS6122975B2 (de) 1986-06-03
FR2319375B1 (de) 1982-07-23
GB1543189A (en) 1979-03-28
US4343787A (en) 1982-08-10
SE431508B (sv) 1984-02-13
ES461217A1 (es) 1978-05-01
DE2633988C2 (de) 1986-09-11
DE2633988A1 (de) 1977-02-10
PT65389B (en) 1978-06-09
BE844544A (fr) 1977-01-27
ES450002A1 (es) 1977-11-16
AU509140B2 (en) 1980-04-24
FR2319375A1 (fr) 1977-02-25
IT1062653B (it) 1984-10-20
CH631891A5 (en) 1982-09-15
NL188266C (nl) 1992-05-18
BR7604876A (pt) 1977-08-09

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