JPS52136161A - Novel prostaglandin derivative* its preparation and its use - Google Patents

Novel prostaglandin derivative* its preparation and its use

Info

Publication number
JPS52136161A
JPS52136161A JP5361977A JP5361977A JPS52136161A JP S52136161 A JPS52136161 A JP S52136161A JP 5361977 A JP5361977 A JP 5361977A JP 5361977 A JP5361977 A JP 5361977A JP S52136161 A JPS52136161 A JP S52136161A
Authority
JP
Japan
Prior art keywords
preparation
prostaglandin derivative
novel prostaglandin
novel
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5361977A
Other languages
English (en)
Japanese (ja)
Other versions
JPS619953B2 (sv
Inventor
Monkada Sarubadooru
Uitsutoteikaa Nooman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of JPS52136161A publication Critical patent/JPS52136161A/ja
Publication of JPS619953B2 publication Critical patent/JPS619953B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP5361977A 1976-05-11 1977-05-10 Novel prostaglandin derivative* its preparation and its use Granted JPS52136161A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB19384/76A GB1583961A (en) 1976-05-11 1976-05-11 Prostacyclin and derivatives thereof
GB3415176 1976-08-17
GB3654776 1976-09-03
GB4344576 1976-10-20
GB5306076 1976-12-20
GB1338977 1977-03-30

Publications (2)

Publication Number Publication Date
JPS52136161A true JPS52136161A (en) 1977-11-14
JPS619953B2 JPS619953B2 (sv) 1986-03-27

Family

ID=27546654

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5361977A Granted JPS52136161A (en) 1976-05-11 1977-05-10 Novel prostaglandin derivative* its preparation and its use

Country Status (12)

Country Link
JP (1) JPS52136161A (sv)
BE (1) BE854463A (sv)
CH (1) CH637948A5 (sv)
DE (1) DE2720999C2 (sv)
DK (1) DK149953C (sv)
FR (1) FR2351111A1 (sv)
GB (1) GB1583961A (sv)
IE (1) IE46036B1 (sv)
IL (1) IL52053A (sv)
NL (1) NL181973C (sv)
NZ (1) NZ184057A (sv)
SE (1) SE436647B (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011059053A1 (ja) 2009-11-13 2011-05-19 東レ株式会社 糖尿病の治療または予防薬

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI71138C (fi) * 1976-12-31 1986-11-24 Erba Farmitalia Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
DE2743283A1 (de) * 1977-09-27 1979-04-05 Hoechst Ag Neue prostacyclin-analoga
IT1088036B (it) 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
DE2811950A1 (de) * 1978-03-18 1979-12-13 Hoechst Ag Neue analoga von prostacyclin
ZA787353B (en) * 1978-05-17 1980-08-27 Wellcome Found Pharmaceutical formulations
US4430340A (en) * 1978-07-17 1984-02-07 The Upjohn Company Stabilization of PGI2 compounds with surfactants
IL58384A0 (en) 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
ZA815504B (en) * 1980-09-15 1982-08-25 Upjohn Co Crystalline pgi2 methyl ester
CH648556A5 (de) * 1981-03-11 1985-03-29 Hoffmann La Roche Fluorprostacycline.
DE3438870A1 (de) * 1983-12-13 1985-06-13 Stellmacher, Gerhard, Ing.(grad.), 8501 Schwaig Spannvorrichtung fuer holzbearbeitungsmaschinen
HU231031B1 (hu) 2016-03-23 2019-12-30 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Megnövelt stabilitású epoprostenol nátrium és eljárás előállítására

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011059053A1 (ja) 2009-11-13 2011-05-19 東レ株式会社 糖尿病の治療または予防薬
US9492422B2 (en) 2009-11-13 2016-11-15 Toray Industries, Inc. Therapeutic or prophylactic agent for diabetes

Also Published As

Publication number Publication date
NL181973C (nl) 1987-12-16
FR2351111A1 (fr) 1977-12-09
CH637948A5 (en) 1983-08-31
SE436647B (sv) 1985-01-14
DK149953C (da) 1987-06-29
DK205377A (da) 1977-11-12
NZ184057A (en) 1979-10-25
DK149953B (da) 1986-11-03
DE2720999A1 (de) 1977-11-24
NL7705141A (nl) 1977-11-15
NL181973B (nl) 1987-07-16
DE2720999C2 (de) 1986-09-18
IE46036L (en) 1977-11-11
JPS619953B2 (sv) 1986-03-27
IL52053A (en) 1983-09-30
IE46036B1 (en) 1983-02-09
IL52053A0 (en) 1977-07-31
SE7705423L (sv) 1977-11-12
BE854463A (fr) 1977-11-10
GB1583961A (en) 1981-02-04

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