JPS5140400A - - Google Patents

Info

Publication number
JPS5140400A
JPS5140400A JP9410375A JP9410375A JPS5140400A JP S5140400 A JPS5140400 A JP S5140400A JP 9410375 A JP9410375 A JP 9410375A JP 9410375 A JP9410375 A JP 9410375A JP S5140400 A JPS5140400 A JP S5140400A
Authority
JP
Japan
Prior art keywords
precipitate
ceramic
hydroxylapatite
polycrystalline
collagen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9410375A
Other languages
Japanese (ja)
Other versions
JPS5941946B2 (en
Inventor
Jaacho Maikeru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of JPS5140400A publication Critical patent/JPS5140400A/ja
Publication of JPS5941946B2 publication Critical patent/JPS5941946B2/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C01B25/327—After-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C13/00—Dental prostheses; Making same
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/70—Preparations for dentistry comprising inorganic additives
    • A61K6/78—Pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/447—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on phosphates, e.g. hydroxyapatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00185—Ceramics or ceramic-like structures based on metal oxides
    • A61F2310/00203—Ceramics or ceramic-like structures based on metal oxides containing alumina or aluminium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Materials Engineering (AREA)
  • Geology (AREA)
  • Dermatology (AREA)
  • Environmental & Geological Engineering (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Structural Engineering (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Composite Materials (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Dental Preparations (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Prosthetics (AREA)
  • Porous Artificial Stone Or Porous Ceramic Products (AREA)

Abstract

1522182 Calcium phosphate ceramics STERLING DRUG Inc 22 July 1975 [2 Aug 1974 7 July 1975] 30706/75 Heading C1A A polycrystalline, sintered ceramic for use as a bone or tooth substitute is made by reacting calcium ion with phosphate ions in aqueous medium at pH of 10-12 to produce a gelatinous calcium phosphate precipitate having a Ca:P molar ratio of 1À44-1À72, separating the precipitate from the solution and heating the precipitate to above 1000‹C but below the temperature at which appreciable decomposition of hydroxylapatite occurs and maintaining said temperature for a sufficient time to effect sintering and maximum densification. When the Ca:P molar ratio is in the range 1À62-1À72 a translucent, isotropic, polycrystalline hydroxylapatite having an average crystalite size of 0À2-3 microns, a density of 3À1-3À14 g/cm<SP>3</SP>, substantially no pores and having cleavage along smooth curved planes is obtained. When the Ca:P ratio is in the range 1À44-1À60, preferably 1À46-1À57 a dense isotropic two-phase ceramic is obtained comprising 14-98% hydroxylapatite and 2-86% whitlockite, said ceramic having substantially no pores and having cleavage along smooth curved planes. The reactants are preferably Ca(NO 3 ) 2 and (NH 4 ) 2 HPO 4 . 0À4-0À6% of an organic binder, e.g. collagen, may be added to the precipitate to prevent cracking during drying. Porous forms of the ceramic may be made by including 5-25% by weight of organic binders such as powdered cellulose, starch, cotton or collagen to the precipitate. Fluoride ions may be introduced into the ceramic, e.g. by standing in 0À5-5% aqueous NaF for 12 hours-5 days.
JP50094103A 1974-08-02 1975-08-01 porcelain Expired JPS5941946B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49424074A 1974-08-02 1974-08-02
US494240 1974-08-02
US59330375A 1975-07-07 1975-07-07
US593303 1975-07-07

Publications (2)

Publication Number Publication Date
JPS5140400A true JPS5140400A (en) 1976-04-05
JPS5941946B2 JPS5941946B2 (en) 1984-10-11

Family

ID=27051362

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50094103A Expired JPS5941946B2 (en) 1974-08-02 1975-08-01 porcelain

Country Status (20)

Country Link
JP (1) JPS5941946B2 (en)
AR (1) AR210581A1 (en)
AT (1) AT370067B (en)
AU (1) AU500991B2 (en)
BR (1) BR7504887A (en)
CA (1) CA1096582A (en)
CH (2) CH618951A5 (en)
DE (1) DE2534504A1 (en)
DK (1) DK347975A (en)
FI (1) FI64131C (en)
FR (1) FR2283104A1 (en)
GB (1) GB1522182A (en)
IE (1) IE42442B1 (en)
IL (1) IL47794A (en)
IT (1) IT1044406B (en)
LU (1) LU73132A1 (en)
NL (1) NL182859C (en)
NO (1) NO138802C (en)
NZ (1) NZ178266A (en)
SE (3) SE426386B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54147940A (en) * 1978-05-09 1979-11-19 Sakurai Seiya Method for supplying trace nutritious elements to food * controlling oxidation and genera bacteria by basic pentacalcium triiphosphate
JPS5550349A (en) * 1978-10-09 1980-04-12 Kureha Chemical Ind Co Ltd Dental compound material
EP0120689A2 (en) 1983-03-24 1984-10-03 Kabushiki Kaisya Advance Transcutaneously implantable element
JPS6270212A (en) * 1985-09-23 1987-03-31 Toa Nenryo Kogyo Kk Calcium phosphate based hydroxyapatite and production thereof
JPS63111875A (en) * 1986-10-30 1988-05-17 京セラ株式会社 Calcium phosphate living body prosthesis material and its production

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7704659A (en) * 1976-05-12 1977-11-15 Battelle Institut E V BONE REPLACEMENT, BONE JOINT, OR PROSTHESIS ANCHORING MATERIAL.
DE2620907C3 (en) * 1976-05-12 1984-09-20 Battelle-Institut E.V., 6000 Frankfurt Anchoring for highly stressed endoprostheses
US4075092A (en) * 1976-08-10 1978-02-21 Research Corporation High surface area permeable material
CH608957A5 (en) * 1977-02-25 1979-02-15 Leuthard Paul E
IL56141A (en) * 1977-12-23 1981-10-30 Sterling Drug Inc Whitlockite ceramic and its manufacture
FR2460657A1 (en) * 1979-07-12 1981-01-30 Anvar BIODEGRADABLE IMPLANT FOR USE AS A BONE PROSTHESIS PIECE
JPS5645814A (en) * 1979-09-25 1981-04-25 Kureha Chem Ind Co Ltd Hydroxyapatite, its ceramic material and its manufacture
FR2478650A1 (en) * 1980-03-24 1981-09-25 Commissariat Energie Atomique CEMENT FOR USE IN FIXING BONE PROSTHESES
FR2485504A1 (en) * 1980-06-30 1981-12-31 Centre Nat Rech Scient Sintered fluoro:apatite for bone prostheses - made with porous structure free from foreign phases
FR2527779B1 (en) * 1982-05-25 1985-05-31 Commissariat Energie Atomique BONE TISSUE SIMULATOR MATERIAL, PREPARATION METHOD THEREOF AND USES THEREOF
DE3424777C2 (en) * 1983-07-08 1995-08-03 Kyushu Refractories Artificial dental materials
NL8402158A (en) * 1983-07-09 1985-02-01 Sumitomo Cement Co POROUS CERAMIC MATERIAL AND METHOD FOR THE PREPARATION THEREOF.
FR2577142B1 (en) * 1985-02-13 1987-03-06 Commissariat Energie Atomique BONE IMPLANT IN CARBON FIBER REINFORCED EPOXIDE RESIN AND PROCESS FOR PRODUCING THE SAME
DE3609432A1 (en) * 1986-03-20 1987-09-24 Kerstin Koerber Sinterable dental impression compounds and their use
US4861733A (en) * 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
JP2608721B2 (en) * 1987-05-12 1997-05-14 旭光学工業株式会社 Method for producing calcium phosphate-based material
JP2934269B2 (en) * 1988-06-21 1999-08-16 ビータ・ツェーンファブリーク・ハー・ラウテル・ゲーエムベーハー・ウント・コ・カーゲー Dispersed ceramic composition
DE58906046D1 (en) * 1989-07-22 1993-12-02 Osborn Johannes Friedrich Prof Osteotropic implant material.
DE3935060C2 (en) * 1989-10-20 1996-05-30 Herbst Bremer Goldschlaegerei Process for the production of a ceramic material for the dental field and its use
DE4302072A1 (en) * 1993-01-26 1994-07-28 Herbst Bremer Goldschlaegerei Ceramic material for dental fillings and / or dental prostheses and method for producing the same
GB9310194D0 (en) * 1993-05-18 1993-06-30 Millenium Bioligix Inc Assessment of osteoclast activity
DE10027946A1 (en) * 2000-06-08 2001-12-13 Wolfgang Wiedemann Dental ceramic used in dentistry as filling material and tooth replacement is anisotropic and contains a large amount of hydroxylapatite
US20170087060A1 (en) * 2011-11-18 2017-03-30 Sofsera Corporation Tooth surface repairing material
CN114890816B (en) * 2022-04-20 2023-04-25 广东欧文莱陶瓷有限公司 Ceramic tile with tree leaf surface and preparation method thereof
CN115651634A (en) * 2022-10-24 2023-01-31 大连工业大学 Perovskite quantum dot/hydroxyapatite composite luminescent material with high thermal stability and preparation method and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR618953A (en) 1927-03-24
US2508816A (en) * 1947-01-25 1950-05-23 Ment Jack De Prosthetic tooth composition
US3609867A (en) 1969-03-10 1971-10-05 Research Corp Plastic bone composition
US3787900A (en) * 1971-06-09 1974-01-29 Univ Iowa State Res Found Artificial bone or tooth prosthesis material
ZA741576B (en) * 1973-04-02 1975-02-26 Lee Pharmaceuticals Dental adhesive composition
JPS5645814A (en) 1979-09-25 1981-04-25 Kureha Chem Ind Co Ltd Hydroxyapatite, its ceramic material and its manufacture
JPS58134992A (en) 1982-01-21 1983-08-11 Kitasato Inst:The Antibiotic substance am-2604-a and its preparation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54147940A (en) * 1978-05-09 1979-11-19 Sakurai Seiya Method for supplying trace nutritious elements to food * controlling oxidation and genera bacteria by basic pentacalcium triiphosphate
JPS5550349A (en) * 1978-10-09 1980-04-12 Kureha Chemical Ind Co Ltd Dental compound material
JPS6330020B2 (en) * 1978-10-09 1988-06-16 Kureha Chemical Ind Co Ltd
EP0120689A2 (en) 1983-03-24 1984-10-03 Kabushiki Kaisya Advance Transcutaneously implantable element
JPS6270212A (en) * 1985-09-23 1987-03-31 Toa Nenryo Kogyo Kk Calcium phosphate based hydroxyapatite and production thereof
JPH0624964B2 (en) * 1985-09-23 1994-04-06 東燃株式会社 Calcium phosphate-based hydroxyapatite and method for producing the same
JPS63111875A (en) * 1986-10-30 1988-05-17 京セラ株式会社 Calcium phosphate living body prosthesis material and its production

Also Published As

Publication number Publication date
CH618951A5 (en) 1980-08-29
IE42442L (en) 1976-02-02
FR2283104A1 (en) 1976-03-26
DK347975A (en) 1976-02-03
SE7508751L (en) 1976-02-03
AR210581A1 (en) 1977-08-31
CH618952A5 (en) 1980-08-29
NZ178266A (en) 1978-04-03
FI752194A (en) 1976-02-03
IT1044406B (en) 1980-03-20
FI64131C (en) 1983-10-10
SE7804813L (en) 1978-04-26
JPS5941946B2 (en) 1984-10-11
GB1522182A (en) 1978-08-23
NL182859B (en) 1988-01-04
NL182859C (en) 1988-06-01
SE426386B (en) 1983-01-17
IE42442B1 (en) 1980-08-13
DE2534504A1 (en) 1976-02-19
NL7509243A (en) 1976-02-04
IL47794A0 (en) 1975-11-25
LU73132A1 (en) 1976-07-01
CA1096582A (en) 1981-03-03
FI64131B (en) 1983-06-30
IL47794A (en) 1978-07-31
NO138802C (en) 1978-11-15
ATA599475A (en) 1982-07-15
AT370067B (en) 1983-02-25
AU8358275A (en) 1977-02-03
AU500991B2 (en) 1979-06-07
NO138802B (en) 1978-08-07
SE425563B (en) 1982-10-11
DE2534504C2 (en) 1989-02-16
BR7504887A (en) 1976-08-31
NO752712L (en) 1976-02-03
FR2283104B1 (en) 1983-04-29

Similar Documents

Publication Publication Date Title
JPS5140400A (en)
US5192325A (en) Ceramic implant
US5017518A (en) Process for producing calcium phosphate ceramics having porous surface
JPS62202884A (en) Live body substitute ceramic material
US5470803A (en) Method for the preparation of carbonated hydroxyapatite compositions
EP0328041A2 (en) Ceramic implant and process for its production
ES476173A1 (en) Whitlockite ceramic
JP2921918B2 (en) Biomaterial with multiphase structure and method for producing the same
US20040057939A1 (en) Artificial bone material
Krajewski et al. The behaviour of apatite-based ceramics in relation to the critical 1150–1250 C temperature range
RU2392006C2 (en) Calcium pyrophosphate-based ceramic biodegradable material manufacture method
JPH0761861A (en) Production of sintered apatite carbonate
JP3215892B2 (en) Method for producing hydroxyapatite whiskers
Abe Phosphate Glasses and Glass--Ceramics
Zimmerman A mathematical theory of enamel solubility and the onset of dental caries: II. Some solubility equilibrium considerations of hydroxyapatite
JP3050071B2 (en) Method for producing sintered calcium carbonate
JPS6366790B2 (en)
JPS63105764A (en) Ceramic for living body prosthesis
GB2008566A (en) Production of bone china
JPH03210271A (en) Production of biomaterial of calcium phosphate system
JPS6418949A (en) Production of powder agent for calcium phosphate based hardened body
JPS5691849A (en) Preparation of catalyst carrier
RAABE et al. OBTAINING DENSE ZNO SINTERS AT TEMPERATURES ABOVE 1050 C
JPH05329201A (en) Production of porous sintered body of calcium apatite
FRANZ MAKING OF FLUORAPATITE CA 5 F (PO 4) 3 DENTAL CERAMICS BY REACTION SINTERING