JPS5018458A - - Google Patents

Info

Publication number
JPS5018458A
JPS5018458A JP49055684A JP5568474A JPS5018458A JP S5018458 A JPS5018458 A JP S5018458A JP 49055684 A JP49055684 A JP 49055684A JP 5568474 A JP5568474 A JP 5568474A JP S5018458 A JPS5018458 A JP S5018458A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP49055684A
Other versions
JPS5614679B2 (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5018458A publication Critical patent/JPS5018458A/ja
Publication of JPS5614679B2 publication Critical patent/JPS5614679B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP5568474A 1973-05-21 1974-05-20 Expired JPS5614679B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00362569A US3822254A (en) 1973-05-21 1973-05-21 Synthesis of 25-hydroxycholesterol

Publications (2)

Publication Number Publication Date
JPS5018458A true JPS5018458A (ja) 1975-02-26
JPS5614679B2 JPS5614679B2 (ja) 1981-04-06

Family

ID=23426617

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5568474A Expired JPS5614679B2 (ja) 1973-05-21 1974-05-20

Country Status (9)

Country Link
US (1) US3822254A (ja)
JP (1) JPS5614679B2 (ja)
AT (1) AT343294B (ja)
BE (1) BE815252A (ja)
CH (1) CH617442A5 (ja)
DE (1) DE2424498C3 (ja)
FR (1) FR2236854B1 (ja)
GB (2) GB1445237A (ja)
NL (1) NL172956C (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53144563A (en) * 1977-05-19 1978-12-15 Chugai Pharmaceut Co Ltd Preparation of steroid derivatives

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5218700B2 (ja) * 1973-02-16 1977-05-24
US3928397A (en) * 1973-03-02 1975-12-23 Eisai Co Ltd New 5-cholestene derivatives and preparation thereof
US3959320A (en) * 1974-09-23 1976-05-25 The Upjohn Company Process and compounds
US3976636A (en) * 1974-10-10 1976-08-24 The Upjohn Company Process and compounds
US3994934A (en) * 1975-01-27 1976-11-30 The Upjohn Company Process for preparing Δ22 -25-oxy substituted sterol derivatives
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
CH628907A5 (en) * 1975-10-10 1982-03-31 Hoffmann La Roche Process for the preparation of 24,25-dihydroxycholesterol derivatives
US3994878A (en) * 1975-10-10 1976-11-30 Hoffmann-La Roche Inc. Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof
US4038272A (en) * 1975-10-20 1977-07-26 Hoffmann-La Roche Inc. Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof
JPS5371056A (en) * 1976-12-08 1978-06-24 Chugai Pharmaceut Co Ltd Steroid derivs.
CA1138859A (en) * 1979-02-15 1983-01-04 Teijin Limited 25-hydroxy-24-oxocholestane derivatives and preparation thereof
CH644873A5 (de) * 1980-02-12 1984-08-31 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten.
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US8399441B2 (en) 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
ES2906865T3 (es) 2013-12-24 2022-04-20 Univ Virginia Commonwealth Uso de sulfatos de colesterol oxigenados (OCS) para tratar la insuficiencia hepática aguda
KR20230152787A (ko) 2016-08-02 2023-11-03 버지니아 커먼웰스 유니버시티 5-콜레스텐-3, 25-디올, 3-술페이트 (25hc3s) 또는 이의 약학적으로 허용 가능한 염, 및 적어도 하나의 시클릭 올리고당을 포함하는 조성물
CN111320663B (zh) * 2018-12-13 2023-01-24 上海医药工业研究院 一种24-胆烯烯酸乙酯中间体的制备方法
WO2020225830A1 (en) 2019-05-09 2020-11-12 Fermenta Biotech Limited Novel method for synthesizing 25-oh cholesterol/calcifediol from phytosterol
CA3136906A1 (en) * 2019-07-09 2021-01-14 Fermenta Biotech Limited Synthesis of cholesterol and vitamin d3 from phytosterols
CN111138512A (zh) * 2019-12-27 2020-05-12 郑州手性药物研究院有限公司 一种合成25-羟基胆固醇中间体的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1052283B (it) * 1968-07-01 1981-06-20 Wisconsin Alumni Res Found Processo per preparare composti del calciferolo e relativi composti
US3846455A (en) * 1972-05-22 1974-11-05 Eisai Co Ltd Process for the preparation of 25-hydroxy-cholesterol and esters thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53144563A (en) * 1977-05-19 1978-12-15 Chugai Pharmaceut Co Ltd Preparation of steroid derivatives
JPS6136000B2 (ja) * 1977-05-19 1986-08-15 Chugai Pharmaceutical Co Ltd

Also Published As

Publication number Publication date
BE815252A (fr) 1974-11-20
NL172956C (nl) 1983-11-16
FR2236854A1 (ja) 1975-02-07
ATA416374A (de) 1977-09-15
NL7406748A (ja) 1974-11-25
CH617442A5 (ja) 1980-05-30
US3822254A (en) 1974-07-02
DE2424498C3 (de) 1981-04-02
JPS5614679B2 (ja) 1981-04-06
AT343294B (de) 1978-05-26
NL172956B (nl) 1983-06-16
DE2424498B2 (de) 1980-06-04
DE2424498A1 (de) 1974-12-12
GB1445237A (en) 1976-08-04
GB1445236A (en) 1976-08-04
FR2236854B1 (ja) 1977-10-21

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