JPS4858000A - - Google Patents

Info

Publication number
JPS4858000A
JPS4858000A JP47118494A JP11849472A JPS4858000A JP S4858000 A JPS4858000 A JP S4858000A JP 47118494 A JP47118494 A JP 47118494A JP 11849472 A JP11849472 A JP 11849472A JP S4858000 A JPS4858000 A JP S4858000A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP47118494A
Other languages
Japanese (ja)
Other versions
JPS5653556B2 (enrdf_load_stackoverflow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS4858000A publication Critical patent/JPS4858000A/ja
Publication of JPS5653556B2 publication Critical patent/JPS5653556B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Addiction (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP11849472A 1971-11-26 1972-11-24 Expired JPS5653556B2 (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00202575A US3814768A (en) 1971-11-26 1971-11-26 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts

Publications (2)

Publication Number Publication Date
JPS4858000A true JPS4858000A (enrdf_load_stackoverflow) 1973-08-14
JPS5653556B2 JPS5653556B2 (enrdf_load_stackoverflow) 1981-12-19

Family

ID=22750450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11849472A Expired JPS5653556B2 (enrdf_load_stackoverflow) 1971-11-26 1972-11-24

Country Status (7)

Country Link
US (1) US3814768A (enrdf_load_stackoverflow)
JP (1) JPS5653556B2 (enrdf_load_stackoverflow)
CA (1) CA974235A (enrdf_load_stackoverflow)
CH (1) CH578568A5 (enrdf_load_stackoverflow)
DE (1) DE2257715C2 (enrdf_load_stackoverflow)
FR (1) FR2160957B1 (enrdf_load_stackoverflow)
GB (1) GB1411129A (enrdf_load_stackoverflow)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63500799A (ja) * 1985-09-06 1988-03-24 ベーカー・カミンス・ファーマシューティカルス・インコーポレーテッド 持続性オピオイド拮抗作用を得るための方法および組成物
JP2015504856A (ja) * 2011-12-06 2015-02-16 ハー・ルンドベック・アクチエゼルスカベット ナルメフェン塩酸塩の回収方法

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322426A (en) * 1980-04-28 1982-03-30 E. I. Du Pont De Nemours And Company 17-Substituted-6-desoxy-7,8-dihydro-6α-methylnoroxymorphone narcotic antagonists
JPS5889377A (ja) * 1981-11-20 1983-05-27 Canon Inc ドツトプリンタ
US4477457A (en) * 1982-10-28 1984-10-16 E. I. Du Pont De Nemours And Company Method for inducing anorexia using nalmetrene
US4478840A (en) * 1983-10-11 1984-10-23 E. I. Du Pont De Nemours And Company Appetite suppressing compositions and methods
US4535157A (en) * 1983-11-01 1985-08-13 Key Pharmaceuticals, Inc. Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone
US4639455A (en) * 1984-10-02 1987-01-27 Key Pharmaceuticals, Inc. Means of aiding in the prevention of sudden infant death syndrome
US4751307A (en) * 1985-01-17 1988-06-14 Mallinckrodt, Inc. Wittig-reaction processes
US5028612A (en) * 1990-03-22 1991-07-02 Hillel Glover Method for treating emotional numbness
JP4668611B2 (ja) * 2002-05-31 2011-04-13 タイタン ファーマシューティカルズ インコーポレイテッド ブプレノルフィンの持続放出のための埋め込み型ポリマー製装置
KR101152183B1 (ko) 2003-03-31 2012-06-15 타이탄 파머슈티컬즈 인코퍼레이티드 도파민 아고니스트의 지속 방출을 위한 이식가능한 폴리머디바이스
CA2614289A1 (en) * 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
CN103012416B (zh) * 2011-09-28 2015-07-01 辽宁海思科制药有限公司 一种盐酸纳美芬的制备方法
CN102584840A (zh) * 2011-12-28 2012-07-18 南京优科生物医药有限公司 一种制备纳美芬化合物的方法
US20140005217A1 (en) 2012-06-27 2014-01-02 H. Lundbeck A/S Nalmefene for reduction of alcohol consumption in specific target populations
HU231191B1 (hu) 2013-04-15 2021-08-30 Szegedi Tudományegyetem Izotóp tartalmú morfin molekulák
CN103204859B (zh) * 2013-04-25 2015-12-02 四川海思科制药有限公司 一种盐酸纳美芬化合物及其制备方法
CA2946698A1 (en) 2014-04-22 2015-10-29 Otsuka Pharmaceutical Co., Ltd. Combination of brexpiprazole and nalmefene and use thereof for treating substance-related disorders

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3162639A (en) * 1964-12-22 G-desoxy-ix-hydroxy-dihydromorphine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3162639A (en) * 1964-12-22 G-desoxy-ix-hydroxy-dihydromorphine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63500799A (ja) * 1985-09-06 1988-03-24 ベーカー・カミンス・ファーマシューティカルス・インコーポレーテッド 持続性オピオイド拮抗作用を得るための方法および組成物
JP2015504856A (ja) * 2011-12-06 2015-02-16 ハー・ルンドベック・アクチエゼルスカベット ナルメフェン塩酸塩の回収方法

Also Published As

Publication number Publication date
FR2160957A1 (enrdf_load_stackoverflow) 1973-07-06
JPS5653556B2 (enrdf_load_stackoverflow) 1981-12-19
GB1411129A (en) 1975-10-22
DE2257715C2 (de) 1985-06-05
DE2257715A1 (de) 1973-05-30
CA974235A (en) 1975-09-09
CH578568A5 (enrdf_load_stackoverflow) 1976-08-13
US3814768A (en) 1974-06-04
FR2160957B1 (enrdf_load_stackoverflow) 1975-11-28

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