JPH115801A - Hydrophobically modified polysaccharide in body care product - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a body care composition, good in compatibility with a salt and solubility in a certain kind of solvent and useful as a shampoo, etc., having the resistance to alkaline conditions by including a specific water-soluble polysaccharide polymer therein. SOLUTION: This body care composition is obtained by including (A) about 0.1-99 wt.% vehicle system, comprising a nonionic water-soluble polysaccharide polymer, containing a water-soluble polysaccharide polymer skeleton (e. g. hydroxyethyl cellulose) and a hydrophobic moiety selected from a 3-alkoxy-2- hydroxypropyl group, a 3-7C alkyl, an arylalakyl, an alkylaryl group and a mixture thereof in which the alkyl moiety is a 2-6C straight chain or a 2-6C branched chain (e.g. 3-butoxy-2-hydroxypropyl group) at about (2:1) to (1,000:1) ratio of the hydrophilic moiety to the hydrophilic moiety of the polymer and hydrophobically modified with ether bonds and further containing water or propylene glycol, etc., as a solvent and (B) one or more other body care ingredients.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

FIELD OF THE INVENTION The present invention relates to the use of hydrophobically modified polysaccharides in body (personal) care products. More specifically, the present invention provides that the alkyl moiety of the hydrophobic moiety is 1
It relates to the use of polysaccharides having ７7 carbon atoms in body care products.

[0002]

Prior to the present invention, non-ionic water-soluble polysaccharides were used in shaving products such as shaving creams and shaving gels, shampoos, shampoo conditioners, hair coloring systems, skin creams, lotions, facial cleansing products, armpits Products, such as deodorants, antiperspirants,
And mixtures thereof, lubricating gels, mouth care products, such as toothpastes and mouthwashes, denture adhesives, hair styling agents, such as hair gels and mousses, soaps, shower gels, body cleansers, cosmetic products, sunscreen products, etc. Used in applications. Widely used commercially available polysaccharides include nonionic water-soluble polysaccharide ethers such as methylcellulose (MC), hydroxypropylmethylcellulose (HPMC), hydroxyethylcellulose
(HEC), hydroxypropylcellulose (HPC), and ethylhydroxyethylcellulose (EHEC) and hydroxypropyl (HP) guar, hydroxyethyl guar, and HP starch and other nonionic starch and guar derivatives. Also, hydrophobically modified polysaccharides have been used in body care products. The use of these prior art polysaccharides in personal care products includes, for example, the compatibility of the personal care product with other ingredients under alkaline conditions,
It may have processing difficulties such as solubility with certain other components, transparency (when needed) and stability. Also, hydrophobically modified polysaccharides have been used in body care products.

[0003] US Patent Nos. 5,106,609, 5,104,646, and 5,100,658 are examples of patents disclosing the use of hydrophobically modified nonionic cellulose ethers in personal care products. These patents disclose high molecular weight (ie, 300,0) for use in hair and skin care cosmetics.
(00-700,000) and the use of long chain alkyl carbon substitutions (ie, 8 to 24 carbons) in the hydrophobic moiety. Also, U.S. Patent Nos. 4,228,277 and 4,35
No. 2,916 discloses hydrophobically modified cellulose ether derivatives modified by long chain alkyl group substitution in the hydrophobic moiety. U.S. Pat. No. 4,845,207 discloses hydrophobically modified nonionic water-soluble cellulose ethers and U.S. Pat. No. 4,939,192 discloses the use of such ethers in composition construction.

[0004]

Some prior art nonionic cellulose ethers have poor solubility or salt in certain solvents used in personal care applications such as polyhydric alcohols. Poor compatibility, while others are not resistant to alkaline conditions. Thus, in the body care industry, it has good compatibility with salts, good solubility in certain solvents and resistance to alkaline conditions, while having no coloring problems when desired There is still a need for non-ionic cellulose ethers to provide the product.

[0005]

SUMMARY OF THE INVENTION The present invention provides a body care composition containing the following components: a) a water-soluble polysaccharide polymer backbone, and wherein the alkyl moiety is 2 to 2;
6 straight or branched chain are 3-alkoxy-2-hydroxypropyl group having carbon atoms, C ₃ -C ₇ alkyl, arylalkyl, hydrophobicity selected from alkyl aryl groups and mixtures thereof And the ratio of hydrophilic to hydrophobic portions of the polymer is about 2: 1.
From about 0.1 to 99% by weight of a vehicle system consisting of a hydrophobically modified nonionic water-soluble polysaccharide polymer, and b) at least one other body care ingredient.

[0006]

DETAILED DESCRIPTION OF THE INVENTION Surprisingly, hydrophobically modified polysaccharides having a short chain alkyl group in the hydrophobic moiety have various advantageous properties over prior art water soluble polysaccharides and their derivatives in personal care products. Has been found. The hydrophobically modified polysaccharide of the present invention can be obtained by using any water-soluble polysaccharide or derivative as a skeleton. That is, for example, hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), methyl cellulose (MC),
Hydroxypropyl methylcellulose (HPMC), ethylhydroxyethylcellulose (EHEC), and methylhydroxyethylcellulose (MHEC); and
Agar, dextran, carob gum, starch, guar, and all of their nonionic derivatives can be modified. The amount of non-ionic substituent such as methyl, hydroxyethyl or hydroxypropyl does not appear to be critical as long as it is present in an amount sufficient to ensure that the ether is water soluble. The polysaccharides of the present invention are non-ionic, have non-ionic substitution sufficient to render them water-soluble, and they are present in amounts up to less than 1% by weight of water-soluble polysaccharides. In addition, it is further substituted with a hydrocarbon group having about 1 to 7 carbon atoms.

A preferred polysaccharide backbone is hydroxyethylcellulose (HEC). HECs that are modified to function in the present invention are commercially available materials. Suitable commercially available materials, Hercules, Inc. under the trademark Natrosol ^{(Natrosol R) (Aqualon Division of} Hercules Incorporated, Wi
lmington, Delaware, USA).

[0008] Short chain alkyl modifiers can be linked to the polysaccharide backbone by ether, ester, or urethane linkages. Preferred are ether linkages, for the reason that the most commonly used reagents in effecting the etherification are readily available and similar to those reactions where the reaction is commonly used for the first etherification, And because the reagent is usually easier to handle than the reagents used for modification by other bonds. Also, the resulting bond is usually relatively resistant to subsequent reactions.

An example of a polysaccharide according to the invention is 3-alkoxy-2-hydroxypropylhydroxyethylcellulose which is completely water-soluble at ambient temperature. Usually, 3-alkoxy-2-hydroxypropylhydroxyethylcellulose used in the present invention is hydroxyethyl molecule-substituted (MS).
(The number of moles of hydroxyethyl substituents per anhydroglucose unit of cellulose in the cellulose molecule is about 1.5 to 3.5). Alkyl glycidyl groups are usually based on the dry weight of the substituted polymer,
It is included in an amount of about 0.05 to 50% by weight, preferably about 0.1 to 25% by weight. The alkyl group of the 3-alkoxy-2-hydroxypropyl group is preferably a straight-chain alkyl group having 2 to 6 carbon atoms. Examples of modifying substances are methyl-, ethyl-, propyl-, butyl-, pentyl
-, And 2-ethylhexyl glycidyl ether.

[0010] Generally, the preferred method for preparing the ethers of the present invention is to convert the nonionic polysaccharide to an inert organic diluent,
It consists, for example, in slurrying in lower aliphatic alcohols, ketones or hydrocarbons and adding at low temperature a solution of an alkali metal hydroxide to the resulting slurry. When the ether is completely wet and the reaction is continuing, continue stirring until complete. The residual alkali is then neutralized, the product is recovered, washed with an inert diluent and dried. Also, C
₃ -C ₇ may halide or carrying out the etherification with a halogen hydride, but they may sometimes less reactive, it may be less efficient, since it may be highly corrosive, epoxide It is preferable to use

[0011] Substantially the same method is used to link hydrocarbon modifiers through ester or urethane linkages. Conventional slurry method for reacting this type of modifier with polysaccharide
(That is, a method without using an alkali) is not effective. The alkaline step is necessary to ensure that the polysaccharide swells to a point where the modifier can react substantially uniformly across all polysaccharide molecules. When the reaction is not substantially uniform throughout the polysaccharide, improved solubility and cloud point properties are not realized.

The hydrophobically modified polysaccharides of the present invention exhibit significantly improved salt tolerance in high salt systems compared to hydrophobically modified polysaccharides that are commercially available for personal care applications. Furthermore, these polysaccharides have improved solubility in solvent systems used in personal care applications compared to hydrophobically modified polysaccharides that are commercially available in the personal care industry. This salt tolerance of the polymer is determined by measuring the cloud point in a 15% sodium chloride solution. The cloud point is the temperature at which the clear solution begins to cloud and the polymer begins to precipitate.

[0013] The hydrophobically modified hydroxyalkyl cellulose of the present invention is an essential component of the vehicle system of personal care products. In some products, this may be substantially the only ingredient required for the vehicle system. Another component that may be present in the vehicle system is a surfactant, which may be either soluble or insoluble in the composition. Also, compatible solvents may be used in the vehicle system, which may be either a single solvent or a mixture of solvents.

Examples of surfactants are anions, non-ionics,
It is a cationic, zwitterionic, or amphoteric surfactant. In the present invention, the surfactant may be insoluble (or soluble) and is present in the composition at the time of use in an amount of about 0.01 to 25% by weight of the composition.

[0015] Synthetic anionic surfactants include alkyl and alkyl ether sulfates. Specific examples of the alkyl ether sulfate that can be used in the present invention include sodium coconut alkyl trimethylene glycol ether sulfate, sodium tallow alkyl trimethylene glycol ether sulfate, sodium tallow alkyl hexaoxyethylene sulfate, and sodium tallow alkyl diethylene glycol. Ether sulfate, and sodium tallow alkyl sulfate.

Nonionic surfactants can be broadly defined as compounds that contain a hydrophobic moiety and a nonionic hydrophilic moiety. Examples of hydrophobic moieties may be alkyl, alkylaromatic, dialkylsiloxane, polyoxyalkylene, and fluoro-substituted alkyl. Examples of hydrophilic moieties are polyoxyalkylenes, phosphine oxides, sulfoxides, amine oxides, and amides.

Cationic surfactants useful in the vehicle system of the compositions of the present invention contain amino or quaternary ammonium hydrophilic moieties, which are positively charged when dissolved in the aqueous compositions of the present invention. I do.

Examples of zwitterionic surfactants are derivatives of aliphatic quaternary ammonium, phosphonium and sulfonium compounds, wherein the aliphatic group may be straight or branched, and the aliphatic substituent Interfaces that can be broadly described as one containing about 8-18 carbon atoms and one being a derivative containing an anionic water-solubilizing group, for example, carboxy, sulfonate, sulfate, phosphate, or phosphonate. Activator.

Examples of amphoteric surfactants that can be used in the vehicle system of the compositions of the present invention are derivatives of aliphatic secondary and tertiary amines, wherein the aliphatic group is straight or branched. One of the aliphatic substituents contains about 8 to 18 carbon atoms and one is an anionic water solubilizing group, such as carboxy, sulfonate, sulfate,
Surfactants that can be broadly described as derivatives containing phosphate or phosphonate.

A water-soluble (or insoluble) surfactant is used with the polysaccharide of the invention at about 0.01 to 25% of the composition.

According to the present invention, the solvent used in the vehicle system is compatible with the other components in the composition. Examples of solvents used in the present invention are water, mixtures of water-lower alkanols, and polyhydric alcohols having 3 to 6 carbon atoms and 2 to 6 hydroxyl groups. Preferred solvents are water, propylene glycol, water-glycerin, sorbitol-water, and water-ethanol. The solvent (when used) in the present invention is 0.1 to 99% of the composition.
It is present in the composition in an amount of% by weight.

The active body care component is optional, as the vehicle system can be the active component. An example of this is the use of the vehicle system in denture adhesives as either creams or powders. However, when an active body care ingredient is needed, it must provide some benefit to the user's body. Examples of substances suitable for inclusion in the body care products of the present invention are as follows.

(1) a fragrance which produces an olfactory reaction in the form of a fragrance;
And deodorant fragrances that can also reduce body odors in addition to imparting an aroma reaction; (2) a skin coolant that produces a tactile response in the skin in the form of a cooling sensation, such as menthol, menthyl acetate, menthyl pyrrolidone carboxylate N- Ethyl-p-menthane-3-carboxamide and other menthol derivatives; (3) emollients that produce a tactile response in the form of increased skin smoothness, such as isosiopropyl myristate, silicone oils, mineral oils and vegetable oils; (4) Deodorants other than fragrances; this function is to reduce or eliminate the amount of microflora on the skin surface, especially those that cause the generation of body malodors; (5) Substances having antiperspirant activity; this function is to reduce or eliminate the appearance of perspiration on the skin surface; ( ) Humidifiers that maintain skin moisture either by preventing evaporation from the skin or by adding moisture; (7) Detergents that remove dirt and oil from the skin; (8) From UV and other harmful rays from the sun Sunscreen actives that protect the skin and hair; according to the invention, the usual therapeutically effective amount will be from 0.01 to 10%, preferably from 0.1 to 5% by weight of the composition; 9) straightens hair, cleanses hair, prevents tangling of hair, and provides styling agents, antidandruff agents, hair growth promoters, hair dyes and pigments, hair fragrances, hair relaxants, hair bleaching agents, hair humidifiers Hair treatments that act as agents, hair oil treatments and anti-frizziness agents; (10) oral care agents for cleaning, whitening, deodorizing and protecting teeth and gums, such as toothpastes and mouthwashes; (11) dentures Denture adhesives that impart adhesive properties to the skin; (12) Shaving products, such as creams, gels and lotions and razor blade lubricating pieces; (13) tissue paper products, such as cleaning tissues; and (14) beauty aids, such as foundation powders, lipsticks and eye care.

The above list is illustrative only and is not a complete list of active ingredients that can be used in a body care composition. Other components used in such products are well known in the art. In addition to the above ingredients commonly used in products for personal care, the compositions of the present invention may optionally include coolants, preservatives, antioxidants, vitamins, activity enhancers, spermicides, emulsifiers, emulsifiers, Viscous agents (eg salt, ie NaC
l, can also contain NH ₄ Cl and KCl) and fats and oils.

[0025] The vehicle and body care compositions of the present invention can be manufactured using conventional compounding and mixing techniques. Methods of making various types of body care compositions are described more specifically in the following examples. It should be understood that the following examples are given for illustrative purposes only, and that other modifications of the present invention may be made within the skill of those skilled in the art without departing from the spirit and scope of the present invention. It is.

[0026]

【Example】

Example 1 Opaque Liquid Soap Composition Component Weight% Water 75.73 Sodium C14-C16 Olefin Sulfonate 7.50 (40% Active) Sodium Lauroyl Sarcosinate (30% Active) 6.66 Cocomido Betainepropyl (35% Active) 6.66 Glycol stearate 1.00 HMHEC1 * 0.80 Propylene glycol 0.50 Glycerin 0.50 Tetrasodium EDTA 0.30 Stearoalkonium chloride 0.10 Methylparaben 0.25 100.00 * This compound is 3-butoxy-2-hydroxypropylhydroxyethylcellulose, 1% aqueous minimum. viscosity
(25 ° C) 2500 cps (Measurement Brookfield LVTD viscometer) and cloud point about 72-78 ° C (glycol treated). Method 1. HMHEC1 * was dispersed in water. pH of about 8.0 to
Raising to 8.5, the polymer was dissolved and mixed for 45 minutes. Methyl paraben was added to the final solution. 2. While slowly stirring the water-soluble polymer solution, stearoalkonium chloride, olefin sulfonate and glycol stearate were added. The mixture was heated to 80 ° C. until all of the glycol stearate melted and the solution became opaque. 3. The remaining components were added while slowly cooling the solution to room temperature. 4. Colorants and fragrances were added. Comparative Example A Transparent Liquid Soap Composition An experiment was conducted in the same manner as in Example 1 with the following changes. Supercol® U product was used in place of HMHEC1. The Supercol material was dispersed in water and mixed for 45 minutes. Then, methyl paraben was added. Other methods are the same.

Example 2 Makeup soap composition component weight% water 65.70 Sodium C14-C16 Olefin sulfonate 20.00 Sodium lauroyl sarcosinate 10.00 Cocoamide MEA 3.0 HMHEC3 * 0.75 Natrosol 250HR 0.25 Disodium EDTA 0.20 Methyl paraben 0.10 100.00 * -Butoxy-2-hydroxypropylhydroxyethyl cellulose, 1% aqueous minimum viscosity
(25 ° C) 2500 cps (Measure Brookfield LVTD viscometer) and cloud point about 82-88 ° C (treated with glycol). Method 1. HMHEC 3 * and Natrosol 250HR were dispersed in water. The pH was raised to about 8.0-8.5 and the polymer was dissolved and mixed for 45 minutes. Methyl paraben was added to the final solution. 2. In a separate container, combine the surfactants, heat to 80 ° C, and mix until uniform. 3. The surfactant solution was added to the water-soluble polymer solution and mixed until well blended. 4. Disodium EDTA was added and added to room temperature. Comparative Example B Makeup Soap Composition The experiment was performed in the same manner as in Example 2. However, Natrosol 250HR material was used in place of HMHEC3. Example 1 and names trademark of supplier and trademark CTFA adopted products used in 2 supplier stearothermophilus benzalkonium Ammonyx 4002 Stepan Chemical Co. chloride Northfield, Illinois Sodium C14 ~ 16 Bio-Terge AS- 40 Stepan Chemical Co Olefin sulfonate Northfield, Illinois Sodium lauroyl Hamposyl L-30 WRGrace & Co. Sarcosinate Nashua, NH Cocoamidopropyl Lexane C Inolex Chemical Co. Betaine Philadelphia, PA Cocoamide MEA Monamid Mona Industries Inc. Paterson, New Jersey Tetrasodium Perma Kleer 100 Stepan Chemical Co. EDTA Northfield, Illinois HMHEC 3 Hercules Incorporated Wilmington, Delaware HMHEC 1 Hercules Incorporated Wilmington, Delaware Natrosol 250HR Hercules Inc. Wilmington, Delaware

Example 3 Infant Hair Conditioner Composition Ingredients % by Weight HMHEC 31.0 Water 74.1 Cetrimonium Chloride (25%) 12.2 Laurinamine Oxide (30%) 10.2 Polyquatemun-17 (62%) 1.5 Propylene Glycol 1.0 Addition of fragrance and preservative up to 100.0 Method 1. HMHEC 3 was dispersed in water with sufficient stirring. pH
Was raised to about 8.0 to 8.5 to dissolve the polymer and mixed for 45 minutes until the dispersion was completely dissolved. 2. The other ingredients were added in the order listed above and mixed well during the addition. Comparative Example C Infant Hair Conditioner Composition An experiment was performed in the same manner as in Example 3, except that the following changes were made. CMC 7HF was used in place of HMHEC3. CMC was dispersed in water and mixed for 45 minutes until fully dissolved. Other ingredients,
Add in the order listed above and mix well between additions.

[0030] Method 1. The HMHEC 1 and Natrosol 250 HHR products were dispersed in water with good agitation, the pH was raised to 8.0-8.5 and mixed until completely dissolved. 2. In a separate container, stearoalkonium chloride and propylene glycol were mixed and heated to 80 ° C. 3. Except for fragrances and preservatives, add the other ingredients listed in Step B all at once to the mixture of stearoalkonium chloride and propylene glycol, in the order listed above, and mix thoroughly between each mix. . 4. Add the surfactant mixture from step 3 to the HMHEC 1 solution,
Mix well and cool to 35 ° C. 5. Flavors and preservatives were then added to form the final composition. Comparative Example D Pearl-like creamy rinse composition The experiment was carried out in the same manner as in Example 4. However, CMHEC 420H is HMHE
Used in place of C1. Examples 3 and 4 of the raw materials and their suppliers CTFA adopted name trade name supplier Kuotemiumu -48 Adogen 470 Sherex Chemical Co.Inc. Dublin , Ohio Oleth -20 Emulphor ON-870 Rhone-Poulenc hydrolyzed animal protein Lexein X- 250 Inolex Chemical Company Philadelphia, Pennsylvania Polyquatermium-17 Mirapol AD-1 Phone-Poulenc Crabury, New Jersy Cocoamidopropyl Ammonyx CDO Stepan Co. Amine oxide Northfield, Illinois Laurin amine oxide Ammonyx LO Stepan Co. Northfield, Illinois cetrimmonium Varisoft E228 Sherex Chemical Co. Inc. (Cetrimonium) Chloride Dublin, Ohio Stearoalkonium Varisoft SDC Sherex Chemical Co. Inc. Chloride Dublin, Ohio Hydroxyethyl Natrosol 250 HHR Hercules Incorporated Cellulose (see above) Wilmington, Delaware Carboxymethyl CMHEC Incorporated hydroxyethyl Wilmington, Delaware cellulose

EXAMPLE 5 Mild Everyday Shampoo Ingredients Weight% Distilled Water Add up to 100.00 Sodium Laureth 19.6 Sulfate, 28% Cocoamidopropyl Betaine, 35% 11.00 Sodium Lauroyl Sarcosinate 9.60 PEG- 150 Distearate 2.90 HMHEC 3 1.10 Methylchloroisothiazolinone 0.08 and methylisothiazolinone, 1.5% Method 1. Mix HMHEC 3 in water (60-
(Heated to 70 ° C.) and dispersed. 2. The surfactant was added all at once to the vessel with sufficient agitation between each addition. 3. PEG-150 distearate was then added to the vessel and mixed until dissolved, after which heating was stopped. 4. Cool the temperature to 40 ° C or below and add fragrance and preservative to the composition. Comparative Example E Mild daily use shampoo The experiment was performed in the same manner as in Example 5. However, Natrosol Plus 43
0 products were used in place of HMHEC 3. Ingredients and their suppliers The name adopted by CTFA Trade name supplier Cocoamidopropyl Lexaine C Inolex Chemical Co. Betaine Philadelphia, Pennsylvania methylchloroiso Kathon CG Rohm & Hass Co. Thiazolinone and Philadelphia, Pennsylvania methyl isothiazolinone methyl paraben Methyl Parasept Kalama Chemicals, Inc. Crabury, New Jersy PEG-150 Distearate Kessco PEG 6000 Stepan Co. DS Northfield, Illinois Sodium Laureth Steol 4N Stepan Co. sulphate, ino North Lauroyl Hamposyl L-30 WRGrace & Co. Sarcosinate Lexington, Massachusetts Hydrophobized Natrosol Plus420 Hercules Incorporated Hydroxyethyl Wilmington, Delaware Cellulose

[0032] Method 1. * HMHEC 4 was added and dispersed in a well-vortexed water vortex in the vessel from Part A. Then, glycerin,
Add with continuous mixing and heat to 80 ° C. for 15 minutes. 2. In a separate container, mix the ingredients of Part B together,
Heated to 0 ° C and mixed well. 3. The components of Part A and Part B were slowly mixed with vigorous mixing to produce an emulsion. The emulsion was maintained at a temperature of about 80 ° C. with constant stirring. 4. The ingredients of Part C were then added to the emulsion and the mixture was continuously mixed while cooling to 40 ° C. 5. The ingredients of Part D (preservative) were added to the new emulsion and mixed well. 6. The composition was then cooled and poured into a container. * HMHEC 4 is 3-butoxy-2-hydroxypropylhydroxyethylcellulose and has an aqueous minimum viscosity (1.0%
5 ° C) with 500 cps (Measurement Brookfield LVTD viscometer) and cloud point about 82-88 ° C (glycol treated). Comparative Example F Hand and Body Lotion An experiment was performed in the same manner as in Example 6. However, Natrosol® 250MR was used in place of HMHEC 4. Name of material and its supplier Company adopted by CTFA Trade name supplier Stearic acid Emerest2400 Henkel Co. Glycol Hoboken, New Jersey Stearic acid Industrene5016K Witoco Co. Newark, NJ Mineral oil Drakeol Penreco Karns City, NJ Cetyl alcohol Crodacol C-95 Croda Inc. Parsippany , NJ propylene glycol, Germaben® Sutton Laboratories diazolidinyl urea, Chatham, NJ methyl and propyl paraben acetylated lanolin Lipolan 98 Lipo Chemical Patterson, NJ hydroxyethyl Natrosol 250MR Hercules Incorporated Cellulose Wilmington, DE

[0033] EXAMPLE 7 Aerosol Shaving Cream Ingredients Amount (g) Deionized water 790.0 Sodium hydroxide (24.6% solution) 9.6 Potassium hydroxide (34.2% solution) 34.2 Stearic acid, double pressed 71.6 coconut oil acid 10.0 Propylene glycol 27.0 Laurinamide DEA 10.0 Coconut oil 2.5 Tallow glyceride 30.0 Preservative (Germaben II) 5.0 HMHEC 3 Slurry 10.0 Total 100.0 Method Add sodium hydroxide and potassium hydroxide to deionized water in container at room temperature to produce shaving cream concentrate did. Next, raise the temperature of the container to 75 ° C,
Stirred for minutes. The stearic acid and coconut acid were separately pre-melted, then each was added to the caustic / water mixture, stirred for 30 minutes, and then cooled to 55 ° C. HMH
EC3 was suspended in propylene glycol and added to the mixture. Laurin Amit ゛ Add DEA (melted), coconut oil, tallow glyceride (melted) and preservative to the container, stir for 15 minutes,
Cool. 225 g of this concentrate was weighed into a standard 12-oz shaving cream can. Next, the can was sealed with a valve using a can for experimental use and a propellant 9.0
g. Comparative Example G Aerosol Shaving Cream The same experiment as in Example 7 was repeated. However, Natrosol
(Registered trademark) 250HR was used in place of HMHEC 3. Ingredient list and suppliers Supplier name of CTFA Trade name supplier Stearic acid Industrene5016 Wito Co. Memphis, Tennessee Palm oil Industrene328 Wito Co. Memphis, Tennessee Laurinamide DEA Standamid LD Henkel Co. Ambler, Pennsylvania Palm oil Palm oil Sigam Chemical Co. St. Louis, Missouri Tallow glyceride Peacock Acidless Geo. Pfau's Sons Co. Tallow Jeffersonvile, Indiana Sorbitol Sorbo (70% active) ICI Americas, Inc. Wilmington, DE Propylene glycol, Germaben II Sutton Laboratories diazodinyl urea, Chatham, NJ Methyl paraben and propylene paraben 88/12 Isobutane / propane A-46 propellant Aeropres Co. Shreveport, Luisiana Propylene glycol Propylene glycol Eastman Chemical Co. Rochester, NY Hydroxyethyl Natrosol 250HR Hercules Inc. Cellulose Wilmington, DE

[0034] 1) For moisture content, modified polymer weight 2) For moisture, adjust moisture content for moisture in polymer *) HMHEC 2 is 3-butoxy-2-hydroxypropylhydroxyethylcellulose, 1% Aqueous minimum viscosity (25
C) 2000 cps (Measurement Brookfield LVTD viscometer) and cloud point about 62-68 C (glycol treatment). Method 1. Add the salt of Part (III) to the water in the vessel with stirring, and add
Heated to 60 ° C to dissolve. During heating, the vessel was covered to prevent moisture loss. 2. Part (I). Weigh glycerin into a beaker and add approximately 5
The polymer was dispersed in glycerin while stirring for a minute until fully dispersed. Add sorbitol and mix the mixture
Stirring was continued for another 10 minutes. Add water and then
Stir for 15-30 minutes, which ensured complete hydration of the polymer (no gel formed). The warmed salt solution was added (no lumps or gels formed) with continuous stirring for an additional 15 minutes until homogenous. The mixture was then transferred to a toothpaste mixer (Ross two-blade planetary mixer). 3. Part (II). Add DCP and water to the mixer and add DC
Mix at low speed for 10 minutes until P is completely wetted. The mixer was then opened and the DCP paste mixture was scraped from the beater and bowl side walls. The mixer was then closed and a vacuum was applied. Mixer at high speed and under vacuum until the DCP paste mixture shows a smooth consistency
Drive for 20 minutes. 4. Part (IV). The SLS was added to the mixer and mixed at low speed for 5 minutes without vacuum. The flavor was added to the mixer and mixed at low speed for 2 minutes. Then open the mixer,
The paste was scraped off the beater and bowl sidewalls. Close the mixer, apply vacuum, mix at medium speed for 15 minutes,
Observation was made for foaming. 5. The mixer was opened to release the vacuum, and the composition was filled into a container as a paste. Comparative Example H Standard Cream Toothpaste With HMHEC2 An experiment similar to Example 8 was repeated. However, Natrosol
250HR (Hercules Inc.) was used in place of HMHEC 2.

[0035] 1) Modified polymer weight with respect to moisture content 2) With respect to moisture, adjust moisture content for moisture in polymer Method 1. Start with part (III). The salt was added to the water under stirring and dissolved by heating to about 60 ° C. During heating, the mixture of salt and water was covered to prevent loss of moisture. 2. Part (I). Glycerin was weighed into a beaker and the polymer was dispersed in glycerin with stirring. The mixture was stirred for 5 minutes until fully dispersed. Sorbitol was added to the dispersion and continuously stirred for another 10 minutes. Water was added and stirred for 15-30 minutes, which ensured complete hydration of the polymer (no gel formed). Add the heated salt solution with stirring until homogeneous
Stirred continuously for 15 minutes (no lumps or gels formed).
The mixture was then transferred to a toothpaste mixer (Ross two-blade planetary mixer). 3. Part (II). DCP was added to the mixer and mixed at low speed for 10 minutes until the DCP was completely wetted. The mixer was then opened and the paste was scraped from the beater and bowl side walls. The mixer was then closed and a vacuum was applied. Mixer at high speed under vacuum until mixture is smooth 2
Driving for 0 minutes. 4. Part (IV). SLS was added and mixed at low speed for 5 minutes without vacuum. The flavor was added and mixed at low speed for 2 minutes. The mixer was then opened and the paste was scraped off the beater and bowl side walls. The mixer was closed and a vacuum was applied. The mixer was mixed at medium speed for 15 minutes and observed for foaming. 5. The mixer was opened to release the vacuum, and the composition was filled as a paste from the mixer.

EXAMPLE 10 Standard Cream Toothpaste Component with HMHEC 1 Weight% Weight (g) (I) HMHEC 1 0.75 15.00 Glycerin, 100% 13.00 260.00 Sorbitol (70% solids) 16.86 337.20 Distilled water 16.96 ² 339.2 (II) ) Dicalcium phosphate, dihydrate 45.00 900.00 (III) tetrasodium pyrophosphate 0.42 8.40 sodium monofluorophosphate 0.76 15.20 sodium saccharin 0.20 4.00 sodium benzoate 0.50 10.00 (IV) flavor 0.55 11.00 (V) sodium lauryl sulfate 1.00 20.00 Distilled water 4.00 80.00 100.00 2000.00 1) Modified polymer weight for moisture content 2) Adjust moisture content to correct polymer moisture Method 1. Part (I). Glycerin was weighed into a beaker. The polymer was dispersed in glycerin by a jiffy mixer under stirring. The mixture of glycerin and polymer was stirred for 5 minutes until fully dispersed. Sodium saccharin and sodium benzoate were added to the dispersion and stirred for another 5 minutes. Sorbitol was then added and mixed for 5 minutes. Then water was added and stirred for 30 minutes. After 30 minutes of stirring, the total weight of the beaker was recorded and again stirred. Heat the solution to 80 ° C,
Mix for minutes. The beaker was weighed again and the weight was adjusted for weight loss due to evaporation. The contents of the beaker were then transferred to a Ross planetary vacuum mixer. 2. During the hydration period of the polymer, the preparation of part (V) started. SLS was added to the water with stirring and dissolved by warming to 5050 ° C. in a water bath. If agglomeration occurred, the process was repeated. 3. Part (II). DCP was added to the mixer and mixed at low speed for 10 minutes to completely wet the DCP. The mixer was then turned off and the paste was scraped from the beater and bowl side walls. The mixer was then closed and a vacuum was applied.
The mixer was run at high speed under vacuum for 20 minutes until a smooth paste was obtained. 4. TSPP was added to the mixer and mixed for 5 minutes. Then
SMFP was added and mixed for 5 minutes. Add saccharin, 5
Mix for minutes. Sodium benzoate was added, mixed at low speed for 5 minutes and stirred at medium speed until smooth for another 10 minutes. 5. Part (IV). SLS was added and mixed at low speed for 5 minutes without vacuum. The flavor was added and mixed at low speed for 2 minutes. The mixer was opened and the paste was scraped off the beater and bowl side walls. The mixer was closed and a vacuum was applied.
The mixer was mixed at medium speed for 15 minutes and observed for foaming. 6. Slow down the mixer, then shut down the mixer and release the vacuum. The contents of the mixer were filled as a paste.

Example 11 Standard Cream Toothpaste Component with HMHEC 1 Weight% Weight (g) (I) HMHEC 1 0.75 15.00 Genuvsco TPH 1 0.25 5.00 (Hercules Inc.) Glycerin 100% 13.00 260.00 Sorbitol (70% solids) 16.86 337.20 Distilled water 16.71 ² 334.2 (II) dicalcium phosphate, dihydrate 45.00 900.00 (III) tetrasodium pyrophosphate 0.42 8.40 sodium monofluorophosphate 0.76 15.20 sodium saccharin 0.20 4.00 sodium benzoate 0.50 10.00 (IV) flavor 0.55 11.00 (V) Sodium lauryl sulfate 1.00 20.00 Distilled water 4.00 80.00 100.00 2000.00 1) Modified polymer weight for moisture content 2) Adjust moisture content to correct polymer moisture Method 1. Part (I). Glycerin was weighed into a beaker. The polymer was dispersed in glycerin by a Jiffy mixer with stirring, and stirred for 5 minutes until fully dispersed. Sodium saccharin and sodium benzoate were added to the mixer and stirred for 5 minutes. Sorbitol is then added,
Mix for 5 minutes. Then water was added and stirred for 30 minutes.
After 30 minutes of stirring, the total weight of the beaker was recorded. The solution was then heated to 80 ° C, mixed at 80 ° C for 15 minutes and weighed again. The weight was adjusted for weight loss due to evaporation. The mixture was then transferred to a Ross planetary vacuum mixer. 2. During the hydration period of the polymer, the preparation of part (V) started. SLS was added to the water with stirring and dissolved by warming to 5050 ° C. in a water bath. If agglomeration occurred, the process was repeated. 3. Part (II). DCP was added to the mixer and mixed at low speed for 10 minutes to completely wet the DCP. The mixer was then turned off and the paste was scraped from the beater and bowl side walls. The mixer was then closed and a vacuum was applied.
The mixer was run at high speed under vacuum for 20 minutes until the paste was smooth. 4. TSPP was added to the mixer and mixed for 5 minutes. Then
SMFP was added and mixed for 5 minutes. Then saccharin was added and mixed for 5 minutes. Then sodium benzoate was added, mixed at low speed for 5 minutes, and stirred at medium speed until smooth for another 10 minutes. 5. Part (IV). SLS was added and mixed at low speed for 5 minutes without vacuum. The flavor was added and mixed at low speed for 2 minutes. The mixer was opened and the paste was scraped off the beater and bowl side walls. The mixer was closed and a vacuum was applied.
The mixer was mixed at medium speed for 15 minutes and observed for foaming. 6. Slowly slow down the mixer and finally stop and release the vacuum. The contents of the mixer were filled as a paste.

Example 12 Oil replenishable (lubricating) gel (or liquid) composition 1 Nonoxynol 9 (2.2%) HMHEC 2 (3.0%) Propylene glycol 94.9% Methyl parasept 0.1% Composition 2 Nonaoxynol 9 (2.2%) HMHEC 2 (1.5%) Nonoxynol 250HHX (Hercules Inc.) 1.5% Water 24.9% Propylene glycol 70.9% Methyl paracept 0.1% Composition 3 HMHEC 2 (4.0%) Propylene glycol 95.9 % Methyl paracept 0.1% Example 4 HMHEC 2 (2.0%) Klucel HF (Hercules Inc.) 1.5% Propylene glycol 94.9% Methyl paracept 0.1% Example 5 HMHEC 2 (0.5%) Klucel HF 0.5% Mineral oil 10.0% The propylene glycol 34.9% water 54.0% methyl paracept 0.1% polymer was dispersed in a vigorously stirred vortex of propylene glycol and / or mineral oil and stirred for 10 minutes. Water was added. Then raise the temperature to 90 ° C, mix for 1 hour,
It was then slowly cooled to about 25 ° C with slow mixing. Nonaoxinol and preservative (if needed) were added with mixing. The composition was then degassed and filled.

Example 13 Denture Adhesive Formulation 1 25.0% CMC 7H3SXF (Hercules Incorpo
rated) 25.0% HMHEC2 45.0% Vaseline (Snow White, Penerico) 5.0% Mineral oil (Drakeol 9, Penerico) Formulation 2 50.0% HMHEC2 45.0% Vaseline (Snow White, Penerico) 5.0 % Mineral oil (Drakeol 9, Penerico) Vaseline is preheated to 60 ° C in a container, mineral oil is added,
Stir for 5 minutes. Next, the polymer was added to the liquid stirred in the container and mixing was continued for 30 minutes. Thereafter, the formulation was transferred to a packout container and cooled to about 25 ° C.

Example 14 Transparent Stick Antiperspirant The preparation of the transparent stick antiperspirant used the following two-phase method: Phase I Total amount of propylene glycol used (part of the antiperspirant salt solution) About 65% of the total) was charged to the reactor. H
MHEC1 was placed in a container and stirred well until dissolved.
The vessel was heated to dissolve the polymer. Once the polymer has dissolved, heat the solution to 110-115 ° C,
Dibenzylidene sorbitol was added and mixed until completely dissolved. This Phase I solution was cooled to about 100 ° C. Phase II In a separate container, place about 35% of the total amount of propylene glycol used (excluding part of the antiperspirant salt solution),
Stir and heat to about 60-70 ° C. Na ₄ EDTA was added and mixed well to form a slurry. The antiperspirant salt solution was then added to the container and mixed well until homogeneous and clear. The emollient dimethicone copolymer was added and the Phase II solution was mixed until clear. Phase mixing: Phase II was added to Phase I while mixing and cooling to 80 ° C. Sometimes, at this point, add the fragrance,
Can mix well. The product was poured into a 1 oz glass jar and allowed to cool overnight. After cooling overnight, the samples were tested for physical and chemical properties. Equipment used: 2 400 ml glass beakers, oil bath, clamp, mechanical stirrer, Jiffy stirrer, and thermometer, and a pollution control cover, such as a plastic wrap.

[0041]

TABLE 1 Total composition of this example 1.49 g of propylene glycol 2. Al / Zr tetrachlorohydrate-gly 36.60 g (30% active solution) 3. Dibenzylidene sorbitol 0.50 g HMHEC1 0.30 5. 5. Sodium EDTA 0.20 6. Dimethicone copolymer (ABIL B 8851) 0.25 Perfume (optional) 1.25 Phase I: propylene glycol 32.30 g Dibenzylidene sorbitol 0.50 g HMHEC1 0.30 g Phase II: propylene glycol 17.40 g Al / Zr tetrachlorohydrate-gly 36.60 g Sodium EDTA 0.20 g Dimethicone copolymer 0.25 g Fragrance (optional) 1.25 g Chemical material, supplier: 1. Propylene glycol (EM Science UPS grade) 2. Al / Zr tetrachlorohydrate-gly (Westwood Chemical Co.) Westchlor A2Z 8160 30% PG solution 3. Dibenzylidene sorbitol (Milliken Chemicals) Millithix 925 4. HMHEC1 (Hercules Incorporated) 5. Sodium EDTA (Aldrich # 5403EJ) 6. Dimethicone copolymer (Goldschmidt Chemical) ABIL B 8851 Spice

Example 15 Lubricating gel

Table 2 Ingredient weight% weight (g) HMHEC2 1.00 4.00 * Klucel ™ HF 1.00 4.00 Propylene glycol 97.9 391.60 Methyl paraben 0.10 0.40 100.00 400. 00 * Hydroxypropylcellulose, Hercules Incorporated, Wilmington, DE. The dry mixture of HMHEC2 and Klucel HF was dispersed in vigorously stirred propylene glycol and mixed for 10 minutes. 2. Next, the temperature was raised to 90 ° C. and mixed for 1 hour. 3. Cool to room temperature with mixing. 4. Preservative methyl paraben was added and mixed for 10 minutes. 5. Put in container. Comparative Example I Lubricant Gel Benecel ™ MP9 instead of HMHEC2
43W (hydroxypropyl methylcellulose, Hercul
es Incorporated), using the same procedure as in Example 15.

Example 16 Lubricating gel

Table 3 Ingredient weight% weight (g) HMHEC2 1.50 7.50 Glycerin, USP 20.00 100.00 Distilled water 78.00 390.00 Diazolidinyl urea, PG methylparaben, propylparaben (Germaben II, ISP) 0 .50 2.50 100.00 500.00 Method: In a water bath, the glycerin was heated to 60 ° C. with stirring and covered with Saran wrap during heating. 2. HMHEC2 was dispersed in the stirred heated glycerin. 3. Distilled water was heated to 60 ° C. in another container, slowly added to the dispersion, and mixed for another 30 minutes while maintaining the temperature at 60 ° C. 4. Next, a preservative was added, cooled to room temperature, and the lubricating gel was placed in a container. Comparative Example J Lubricating Gel Natrosol ™ 25 instead of HMHEC2
0H NF (Hydroxyethylcellulose, Hercules I
ncorporated), using the same procedure as in Example 16.

Example 17 Denture Adhesive A 100 g batch of denture adhesive having the following composition was prepared: Method: Vaseline was weighed into a 250 ml beaker.
The beaker was placed in a circulating oil bath at 67 ° C. 0.25 on axis
The contents were agitated at low speed by an electric mixer having two 1.5 inch diameter propellers spaced apart by inches. The contents were brought to 65 ° C. and the polymer was added slowly, adjusting the speed of the mixer to maintain stirring of the mixture. Mixing was continued for 1 hour. Preparation of artificial saliva for mechanical testing An artificial saliva of the following composition was prepared:

[Table 4] The pH of the dilution was adjusted to 7.0 with sodium phosphate (dibasic, heptahydrate).

Testing Denture Adhesive: MTS Cyclic Compression / Tension Test: Apparatus is 3 "in diameter
Plexiglas top plate and 2 "diameter Plexiglas
A specially designed device with a lower plate and a 4.5 ″ diameter Plexiglas cylinder surrounding it to form a reservoir. A special adapter was provided for mounting to this MTS device. A 2 ml DA sample was placed from a 5 ml disposable syringe and spread evenly over the lower stage of the test device, and artificial saliva was placed in the reservoir of the device just as the sample surface was immersed (~ 180 m).
l). The upper stage of the instrument was contacted with the sample, kept at an initial position span of 0.04 "above the lower plate, with a crosshead speed of 0.20 inch / min and a full scale load of 20.
The span was varied between 0.06 "and 0.03" by rotating the device at ５０50 lb. This test was performed for 200 cycles. Table 20 shows the tension and compression force. The average of three measurements was recorded. [GAF Chemicals Co., Method
and Procedure Number MP-875-W, September 7, 1989;
Gilbert Banker and David P. DeMagstris, Evaluation
of Adhesional Properties of Polyber samples using
the Instron Universal Stress / Strain Analyzer, unp
ublishued Purdue University report for GAF, July 1
0, 1979.]

Comparative Example K Denture Adhesive Natrosol ™ 25 instead of HMHEC2
0HX (hydroxyethylcellulose, Hercules Incor
porated) using the same method as in Example 17.

Example 18 Transparent stick antiperspirant The preparation of the transparent stick antiperspirant used the following two-phase method: Phase I Total amount of propylene glycol used (part of the antiperspirant salt solution) About 65% of the total) was charged to the reactor. H
MHEC1 was placed in a container and stirred well until dissolved.
The vessel was heated to dissolve the polymer. Once the polymer has dissolved, heat the solution to 110-115 ° C,
Dibenzylidene sorbitol was added and mixed until completely dissolved. This Phase I solution was cooled to about 100 ° C. Phase II In a separate container, place about 35% of the total amount of propylene glycol used (excluding part of the antiperspirant salt solution),
Stir and heat to about 60-70 ° C. Na ₄ EDTA was added and mixed well to form a slurry. The antiperspirant salt solution was then added to the container and mixed well until homogeneous and clear. The emollient dimethicone copolymer was added and the Phase II solution was mixed until clear. Phase mixing: Phase II was added to Phase I while mixing and cooling to 80 ° C. At this point, the flavor was added and mixed well. The product was poured into a 1 oz glass jar and allowed to cool overnight. After cooling overnight, the samples were tested for physical and chemical properties. Equipment used: 2 400 ml glass beakers, oil bath, clamp, mechanical stirrer, Jiffy stirrer, and thermometer, and a pollution control cover, such as a plastic wrap.

[0048]

TABLE 5 Total composition of this example 1.49 g of propylene glycol 2. Al / Zr tetrachlorohydrate-gly 36.60 g (30% active solution) 3. Dibenzylidene sorbitol 0.50 g 4. HMHEC1 0.30 g 5. 0.20 g of sodium EDTA Dimethicone copolymer (ABIL B 8851) 0.25 g 87.45 g Phase I: propylene glycol 32.07 g Dibenzylidene sorbitol 0.50 g HMHEC1 0.30 g 32.87 g Phase II: propylene glycol 17.60 g Al / Zr tetrachlorohydrate- gly 36.60 g sodium EDTA 0.20 g dimethicone copolymer 0.25 g 54.65 g

Comparative Example L The same method as in Example 18 was performed, except that CMHEC420H was used instead of the transparent stick-shaped antiperspirant HMHEC1.

Table 6 Materials and suppliers for antiperspirant sticks: material supplier propylene glycol (USP grade) EM Science Gibbstown, NJ Al / Zr tetrachlorohydrate-gly Westwood Chemical Corporation Westchlor A2Z 8160 30% PG solution Middeletown, New York Dibenzylidene Sorbitol Milliken Chemicals Millithix 925 HMHEC1 Hercules Incorporated Wilmington, DE Carboxymethyl Hydroxyethyl Hercules Incorporated Cellulose CMHEC420H Sodium EDTA Aldrich # 5403EJ Aldrich Chemical Company Milwaukee, Wisconsin Dimethicone Copolymer ABIL B 8851 Goldschwellt Corp.

Example 19 Shampoo

Ingredient weight% distilled water 58.80 ammonium lauryl sulfate, 30% (Stepanol AM) 27.50 disodium cocoamphodiacetate, 50% (Miranol C2M) 6.90 sodium laureth sulfate, 60% (Steol CS460) 5.70 HMHEC2 0.60 Germaben II 0.50 Citric acid pH 5.5 100.00 Method 1. The water was heated to 70 ° C. with stirring in a water bath and covered to prevent water loss. 2. HMHEC2 was added slowly to the stirred water. 3. The mixture was cooled to 40C. 3. Each time the remaining ingredients were added, they were mixed well. 4. The pH was adjusted to 5.5 with citric acid. Comparative Example M Shampoo Benecel MP943W instead of HMHEC2
And the same method as in Example 19 was carried out.

[0051]

[Table 8] materials for shampoos and suppliers CTFA name trade name supplier of ammonium lauryl sulfate Stepanol AM Stepan Chemical Co. Northfield, IL disodium here Anne follower diacetate Miranol C2M Rhone-Polenc, (Disodium cocoamphodiacetate) Cranbury, NJ Sodium laureth sulfate Steol CS460 Stepan Chemical Co. (Sodium laureth sulfate) Preservative Germaben II Sutton Labs Chatham, NJ Hydroxypropyl methylcellulose Benecel Hercules Inc. MP943W Wilmingto
n, DE

Example 20 Pearl Gloss Shampoo

Table 9: Component weight% weight (g) distilled water q. s. to 100.00 347.
25 TEA-Lauryl sulfate (40% activity) (Stepanol WAT) 15.00 75.0 Sodium lauroamphoacetate (and) Sodium trideceth sulfate (Miranol MHT) 10.00 50.00 Cocamide DEA (Ninol 40C0) 2.50 12.50 Glycol stearate (Emerest 2400) ) 1.20 6.00 propylene glycol (and) diazolidinyl urea (and) methylparaben (and) propylparaben (Germaben II) 0.75 3.75 HMHEC1 0.60 3.00 N-Hance ( R) 3000 cationic guar 0.50 2.50 citric acid (50% solution) pH adjust - 100.00 500.00

Method: The N-Hance ™ product was dispersed into the well-stirred water in the container by slowly adding.
The pH was reduced to 7.0 with citric acid to facilitate dissolution of the surface-treated N-Hance, and the solution was heated to 50 ° C. 2. Add NMHEC to the heated N-Hance ™ solution
1 was added slowly and mixed until completely dissolved. 3. The temperature rose to 70 ° C. Next, TEALS and glycol stearate were added sequentially. The mixture was stirred well between the additions. When homogeneous, the heating was stopped. Mixing was continued. 4. When the temperature reached 55 ° C., the remaining components were added sequentially. 5. The pH was adjusted to 5.0 with a citric acid solution. 6. Cool to 40 ° C. and add perfume. Comparative Example N Pearlescent Shampoo Benecel MP943W instead of HMHEC1
(Hercules Incorporated) using the same method as in Example 20.

[0054]

TABLE 10 Ingredients and Supplier for Pearlescent Shampoo CTFA Trade Name Supplier TEA-Lauryl Sulfate Stepanol WAT Stepan Company Northfield, Illinois Sodium Lauroamphoase Miranol MHT Rhone-Poulenc Tate (and) Sodium Cranbury, NJ Tricedes sulfate (Sodium lauroamphoacetate (and) sodium trideceth sulfate) Cocamide DEA Ninol 40C0 Stepan Company Northfield, IL Glycol stearate Emerest 2400 Henkel Corporation Hoboken, NJ Propylene glycol (and) Germaben II Sutton Lab Diazolidinyl urea (and) Chatham, NJ Methylparaben (and) propylparaben Guar hydroxypropyl N-Hance ™ 3000 Hercules Incorporated Trimonium Chloride Wilmingto
n, DE

Example 21 Sunscreen lotion

TABLE 11 Ingredient weight% weight (g) Mineral oil (Kearol, Witco) 13.00
65.00 Polyoxypropylene 15 stearyl ether (Arlamol E, ICI) 6.00 30.00 Octyl methoxycinnimate (Neo Heliopan AV, H & R) 5.00 25.00 Benzophenone-3 (Uvinul M40, BASF) 3.00 15.00 Hydrogenated castor oil (Castor Wax, Ross) 1.40 7.00 Sorbitan monoisostearate (Arlacel 987, ICI) 1.20 6.00 Polyoxyethylene polyol fatty acid ester (Arlatone T, ICI) 1.00 5.00 O Wax 77W Ross 1.00 5.00 Polyoxyethylene fatty acid ester (Arlacel 989, ICI) 0.50 2.50 B. HMHEC1 0.50 2.50 Distilled water 63.60 318.00 Glycerin 3.00 15.00 Magnesium sulfate 0.70 3.50 Diazolidinyl urea, PG, methylparaben, propylparaben (Germaben II, ISP) 0.10 0.50 100.00 500.00

Method 1. All components of Part A were mixed by stirring in a container. 2. The temperature was raised to 70 ° C. and the mixture was stirred for 30 minutes. 3. For Part B, HMHEC1 was dispersed in distilled water. Raise the pH of the slurry to 8.5 with NaOH,
Mix until dissolved. Glycerin, magnesium sulfate and preservative were added with sequential mixing. The mixture was agitated between the additions to prevent lumps. 4. Add Part B slowly to Part A while stirring,
Stirred at 70 ° C. for 30 minutes. 5. The new mixture was cooled to room temperature with stirring and placed in a container. Comparative Example O The same method as in Example 21 was performed, except that CMC 7HF NF was used instead of sunscreen lotion HMHEC1.

[0057]

Table 12 Materials and suppliers for sunscreen lotions CTFA name Trade name Supplier Mineral oil Klearol Witco Corporation Dublin, OH Polyoxypropylene 15 Arlamol E ICI Surfactants Stearyl ether Wilmington, DE Octyl methoxycinnimate Neo Heliopan AV H & R Corporation (Octyl Methoxycinnimate) Springfield, NJ Benzophenone-3 Uvinul M40 BASF Corporation Washington, NJ Hydrogenated castor oil Castor Wax Ross Sorbitan monoisostearate Arlacel 987 ICI Surfactants Polyoxyethylene polyol Arlatone T ICI Surfactants Fatty acid ester Ozokerite wax O Wax 77W Ross Polylaceethylene fatty acid Arlacel 989 ICI Surfac
tans ester diazolidinyl urea, PG, Germaben II Sutton Lab
s Methylparaben, propyl Chatham, NJ Paraben carboxymethylcellulose CMC 7HF NF Hercules Incorporated

Example 22 Hydro-alcoholic roll-on

[Table 13] Part component weight% weight (g) A REACH® 501 solution 40.00 160.00 (50% Al chlorohydrate) B Procetyl AWS 2.00 8.00 (PPG-5 ceteth-20) C HMHEC4 0.20 0.80 D deionized water 15.70 62.80 E SD alcohol 40 41.10 164.40F Fragrance (d) 1.00 4.00 100.00 400.00 Method: HMHEC4 was dispersed in deionized water (D) in a container, and the pH of the dispersion was adjusted to 8.5 with a NaOH solution. The dispersion was then mixed for 30 minutes. 2. Component A was slowly added to the dispersion and rapidly mixed and dissolved by overhead stirring. 3. Components B and E were combined in a separate vessel and then added slowly to the remainder of the batch with constant stirring. 4. The fragrance was then added and mixed for 5 minutes. 5. The resulting mixture was poured into a roll-on container. Comparative Example P Hydro-Alcoholic Roll-On Instead of HMHEC4 Natrosol 250MR
Example 22 using CS (Hercules Incorporated)
The same method was used.

[0059]

Table 14 Materials and Suppliers for Hydro-Alcohol Roll-Ons CTFA Trade Name Supplier Aluminum Chlorohydrate REACH 501 Rehies Incorporation Berkeley Height, NJ PPG-5 ceteth-20 Procetyl AWS Croda Incorporation Parsippany, NJ Ethyl Alcohol SD Alcohol 40 Fragrance # Q-7148 Quest International Classic Oriental / Fragrances Inc. Spice Mount Olive, NJ Hydroxyethylcellulose Natrosol 250MR CS Hercules Incorporated Wilmington, DE

Example 23 Shower gel

Table 15: Component weight% weight (g) Deionized water qs to 100.00 282.10 B. HMHEC1 (Hercules Inc.) 0.95 4.75 C.I. Sodium laureth sulfate (Steol CS460, Stepan) 11.53 57.65 Disodium laureth sulfosuccinate (Stepan Mild SL3, Stepan) 11.80 59.00 Disodium cocoamphodiacetate (Miranol C2M Conc NP, Rhone-Poulenc) 6.00 30.00 Sodium lauroyl sal Cosinate (Crodasinic LS 30, Croda) 7.25 36.25 Propylene glycol 2.00 10.00 Quaternized wheat protein (WheataFlor, Croda) 1.00 5.00 Hydrolyzate and hydrolyzed wheat protein and wheat germ oil & polysorbate 20 glycol distearate and laureth-4 And CAPB (Euperlan PK 3000, Henkel) 2.00 10.00 Disodium EDTA (EDETA BD, BASF) 0.10 0.50 Fragrance (Drom 229033, Drom) 0.35 1.75 Phenoxyethanol and methyl paraben and ethyl paraben and propyl paraben and butyl paraben (Phinonip, Nipa) 0.60 3.00 100.00 500 .00 Method: HMHEC was dispersed in well stirred water to form a slurry. 2. Adjust the pH of the slurry to 8.5 with NaOH solution,
The slurry was mixed until the lumps disappeared and a solution formed.
Next, the ingredients of Phase C were added to the solution in the above order. Mix for 1 minute between additions or until the mixture is homogeneous. 3. Adjusting the pH of the final gel product to 5.3-5.7,
Put in container.

Comparative Example Q The same method as in Example 23 was performed, except that N-Hance 3196 was used instead of the shower gel HMHEC1. The polymer was dispersed in water and mixed for 5 minutes. The pH of the slurry is 6.0-6.0
After lowering to 7.0 and mixing for 1 hour or until there were no lumps, phase C was added as above.

[0062]

[Table 16] for the shower gel materials and suppliers CTFA name trade name Supplier Guar hydroxypropyltrimonium N-Hance (TM) Hercules Incorporated Moniumukurorido 3196 Wilmington, DE Sodium laureth sulfate Steol CS460 Stepan Company Nothfield, NJ Disodium Laureth Sulfo Stepan Mild SL3 Stepan Company succinate disodium cocoampho Miranol C2M Rhone-Poulenc diacetate Conc NP Cranbury, NJ sodium lauroyl Crodasinic LS30 Croda Incorporated sarcosinate Parsipanny, NJ quaternized wheat protein Euperlan PK 3000 Henkel Corporation Wheat Protein and Wheat Hoboken, NJ Germ Oil & Polysorbate 20 Glycol Distearate and Laureth-4 and CAPB Disodium EDTA EDETA BD BASF Corporation Washington, NJ Fee Drom 229033 Drom International Towaco, NJ Phenoxyethanol and Phinonip Nipa Hardwicke Inc. methyl and ethyl Wilmington, DE paraben and propyl paraben and butyl paraben guar hydroxypropyltrimonium N-Hance 3196 Hercules Incorporated Moniumukurorito Bu Wilmington, DE

[0063]

[Table 17]

[0064]

[Table 18]

[0065]

[Table 19] Comparative performance data of various formulations Formulation Example Viscosity cps @ 25 ° C pH Cuban Stringiness Sample storage temperature (Cuban) Room temperature 40 ° C 5 ° C Cream 8 116000 (3) 176,000 109,000 7.1 2.0 71.2 Toothpaste H 262,000 425,000 295,000 7.1 6.5 67.0 ND = Not measured. All data are storage stability after 24 hours. (3) Viscosity was measured using a Brookfield Helipath viscometer at 5.0 rpm, 25 ° C. for 3 minutes with spindle rotation “1”. Cuban value: reflects the upright character of a dentifrice. Threading value: reflects the characteristic of the dentifrice being cut into strips.

[0066]

[Table 20]

Claims (41)

[Claims] 1. A body care composition comprising the following components: a) a water-soluble polysaccharide polymer backbone, and wherein the alkyl moiety is 2 to 2.
6 straight or branched chain are 3-alkoxy-2-hydroxypropyl group having carbon atoms, C ₃ -C ₇ alkyl, arylalkyl, hydrophobicity selected from alkyl aryl groups and mixtures thereof And the ratio of hydrophilic to hydrophobic portions of the polymer is about 2: 1.
From about 0.1 to 99% by weight of a vehicle system consisting of a hydrophobically modified nonionic water-soluble polysaccharide polymer, and b) at least one other body care ingredient. 2. The composition according to claim 1, which also comprises about 0.01 to 25% by weight of the body care composition of a surfactant. 3. The composition according to claim 2, wherein the surfactant is selected from the group consisting of anionic, nonionic, cationic, zwitterionic, amphoteric surfactants, and mixtures thereof. 4. About 0.1-99% by weight of the body care composition
The composition according to claim 1, further comprising a compatible solvent or solvent mixture. 5. The solvent or solvent mixture is selected from the group consisting of water, water-lower alkanol mixtures, polyhydric alcohols having from 3 to 6 carbon atoms and from 2 to 6 hydroxyl groups, and mixtures thereof. 5. The composition of claim 4, wherein the composition is prepared. 6. The composition of claim 5, wherein the solvent or solvent mixture is selected from the group consisting of water, propylene glycol, water-glycerin, sorbitol-water, water-ethanol, and mixtures thereof. 7. About 0.1-99% by weight of the body care composition
The composition according to claim 2, further comprising a compatible solvent or a solvent mixture of the following. 8. The hydrophobically modified polysaccharide backbone comprises hydroxyethyl cellulose (HEC), hydroxypropyl cellulose (HPC), methyl cellulose (MC), hydroxypropyl methyl cellulose (HPMC), ethyl hydroxyethyl cellulose (EHEC), and methyl hydroxyethyl cellulose (HEC). MHEC), and the composition of claim 1, selected from the group consisting of agar, dextran, locust bean gum, starch, guar, and nonionic derivatives thereof, and mixtures thereof. 9. The polysaccharide backbone is HEC and the hydrophobic moiety is 3-butoxy-2-hydroxypropyl.
A composition according to claim 1. 10. The composition according to claim 4, which also contains a thickening effective amount of a salt.
A composition according to claim 1. 11. A hair or skin care composition comprising an effective amount of the body care composition according to claim 7 and a solvent. 12. A shampoo containing an effective amount of the body care composition according to claim 4. 13. A conditioner containing an effective amount of the body care composition of claim 4. 14. A shampoo conditioner containing an effective amount of the composition of claim 1. 15. A sun care product comprising an effective amount of the body care composition of claim 1 and a solvent. 16. A shower gel containing an effective amount of the cleaning composition according to claim 1. 17. A soap containing an effective amount of the body care composition according to claim 1. 18. A hair styling gel composition comprising an effective amount of the body care composition of claim 1. 19. A hair styling gel composition comprising an effective amount of the body care composition of claim 4. 20. An anti-dandruff composition comprising an effective amount of the body care composition of claim 7 and a solvent. 21. A hair growth promoting composition comprising an effective amount of the body care composition of claim 1. 22. A hair coloring composition comprising an effective amount of the body care composition of claim 1. 23. A hair bleach composition comprising an effective amount of the body care composition of claim 1. 24. A hair frizziness preventing composition comprising an effective amount of the body care composition according to claim 1. 25. A hair relaxant composition comprising an effective amount of the body care composition of claim 1. 26. A toothpaste composition comprising an effective amount of the body care composition of claim 1. 27. A mouthwash composition comprising an effective amount of the body care composition of claim 1. 28. A denture adhesive composition comprising an effective amount of the body care composition of claim 1. 29. A shaving product composition comprising an effective amount of the body care composition of claim 1. 30. A lubricating gel composition comprising an effective amount of the body care composition of claim 1. 31. A spermicidal gel composition comprising an effective amount of the body care composition of claim 1. 32. A cosmetic aid composition comprising an effective amount of the body care composition of claim 1. 33. An underarm solid stick composition comprising an effective amount of the body care composition of claim 1. 34. An underarm gel composition comprising an effective amount of the body care composition of claim 1. 35. An underarm liquid composition comprising an effective amount of the body care composition of claim 1. 36. The underarm liquid composition according to claim 35, comprising an aerosol component. 37. The composition of claim 1, further comprising an oil-in-water or water-in-oil emulsion. 38. A cleaning composition comprising an effective amount of the composition of claim 1. 39. A hair styling and anti-tangling composition comprising an effective amount of the body care composition of claim 1. 40. A razor blade lubricating strip composition comprising an effective amount of the body care composition of claim 1. 41. A cleaning tissue composition comprising an effective amount of the body care composition of claim 1.