JPH11189519A - Etiquette deodorant and deodorization of body odor - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject deodorant in low costs that has excellent effect to-deodorize or reduce unpleasant odors as mammalian body smell without problem on safety by using an extract from sugar cane. SOLUTION: This deodorant contains an extract from sugarcane (a deodorization substance that is obtained by treating the raw material selected from sugarcane juice or sugarctune molasses with column chromatography). The extract from the sugarcane product is prepared by allowing the raw material to pass through the column filled with synthetic adsorbent as an immobilized carrier and the adsorbed components are eluted with an eluent selected from water, methanol, ethanol and their mixtures into fractions and the objective deodorant is obtained as some eluate tractions.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a deodorant and a method for deodorizing or reducing body odor represented by halitosis, sweat odor, fat odor, physiological odor and the like of animals.

[0002]

2. Description of the Related Art The Japanese are said to be clean and ethnic. However, as the living environment has been enriched and the housing and social environments have changed, the degree of this has been increasing year by year. In addition, with the airtightness of the environment due to urbanization in recent years and changes in the social environment, communication between people has become more frequent, and in order to not hinder communication,
The unpleasant odor of body odor that the partner dislikes, such as bad breath, sweat odor, fatty odor,
Deodorization of body odor represented by physiological odor is indispensable. In addition, pet animals are treated in the same manner as the owner's family, and in most cases, the pet animals are themselves cleaned. Furthermore, in the livestock industry, particularly for raising livestock such as horses, pigs, cattle, and chickens, the body odor generated by them is an extremely important problem from the viewpoint of environmental hygiene against malodor.
As a result, various deodorants or deodorants have been developed as etiquette products.

[0003] Conventionally, bad breath, which is an unpleasant odor of the body odor of animals,
As a deodorant for sweat odor, fat odor, physiological odor, etc.,
A method of masking unpleasant odors with aromatic substances such as cinnamon and jasmine (sensory deodorization) so that the odors of interest cannot be perceived, and neutralizing, oxidatively decomposing, and other chemical reactions of the substances causing unpleasant odors A method of deodorizing (chemical deodorization) or using a bactericidal drug for the purpose of suppressing the activity of bacteria resident in the oral cavity that contributes to bad breath, preventing spoilage and preventing generation of unpleasant odor A method (biological method) or a method of adsorbing on an adsorbent such as activated carbon and cyclodextrin to fix and deodorize (physical deodorization) and the like are known.

[0004] For example, a deodorant for bad breath needs to be safe in the body even when it is eaten and consumed. For this reason, plant extracts have attracted attention, and deodorants have been studied, mainly on plants that have been consumed. For example, green tea extract (JP-A-60-185558), red beet, cacao,
Coffee, parsley extract (JP-A-60-207664), perilla extract (JP-A-60-214726), persimmon extract (JP-A-61-87562), blowball extract (JP-A-61-2)
06448), crushed mushrooms (Japanese Patent Laid-Open No. 62-181)
048), touki extract (JP-A-5-317397), tea leaf tannin fraction (JP-A-2-284997), Apiaceae plant extract (JP-A-6-190027), mugwort extract ( JP-A-7-33636, mushroom extract (JP-A-2-277456, JP-A-5-38358) and tamarind husk (JP-A-7-255824) are effective for deodorization. It has been.

However, in general, in the case of a deodorant based on masking of unpleasant odor, there is a high tendency to adopt a substance having a strong odor as an aromatic substance for masking. Is high, the third person often feels unpleasant even if it is considered to be fragrant depending on the person who senses the scent, and when the scent of the aromatic substance is mixed with the odor to be masked, temporary Anyway, there is a problem in that an extremely unpleasant odor is often present. In addition, among the conventional deodorants, those based on decomposition have problems in that they may generate an unpleasant odor due to decomposition during application, and their effects are not persistent. There is a problem in that those based on are not immediately effective and have low deodorizing ability.

[0006] Further, the plant extract-based deodorant has problems such as having a bitter taste, astringent taste, etc., a strong smell, or exhibiting a unique color. Therefore, if an effective amount of such a substance is used as a deodorant, it may affect the taste, flavor, color, etc. of the applied food or oral agent. Is limited. In addition, there is a problem that the selectivity of the deodorizing effect for each malodorous substance is large and the deodorizing effect is weak. Or, deodorant substances derived from natural products are generally expensive because the raw materials themselves are expensive or the cost of extraction is high, and the price is increased for foods, pharmaceuticals, etc. to which these are applied. There are also problems.
In addition, there are some quality problems such as safety and storage stability when used for food.

[0007]

DISCLOSURE OF THE INVENTION The present invention provides an inexpensive deodorant which has an excellent effect for deodorizing or reducing an unpleasant odor of body odor of an animal, is inexpensive and has no problem in safety. It is intended to provide an odor method.

[0008]

Means for Solving the Problems The present inventors have made intensive studies on deodorants and methods for deodorizing or reducing the unpleasant odor of body odor of animals. The inventors have found that the present invention is effective in deodorizing or reducing odors, and have completed the present invention.

The first aspect of the present invention is an etiquette deodorant applied to an unpleasant odor source to deodorize or reduce an unpleasant odor of body odor of an animal, characterized by containing an extract derived from cane sugar. To provide an etiquette deodorant.

A second aspect of the present invention is a method for deodorizing or reducing an unpleasant odor of body odor of an animal, which comprises contacting an extract derived from sugar cane with an unpleasant odor component generated from the animal. Is provided.

[0011]

BEST MODE FOR CARRYING OUT THE INVENTION In the present invention, the unpleasant odor of the body odor of an animal refers to bad odor (for example, odor derived from the gastrointestinal tract, putrid odor derived from microorganisms in the oral cavity, or odor caused by food, drink, tobacco, alcohol, etc.). ) Or sweat odors (including foot odor, armpit odor, etc.), and fatty odors generated from the body surface (including odors such as skin debris such as dirt, secretions, and odors decomposed by microorganisms, etc.), Menstrual odors due to gender differences and age differences. The present invention is particularly effective against odors selected from bad breath, sweat odor, fatty odor and physiological odor.

In the present invention, animals include humans, domestic animals, and wild birds and animals.

[0013] In the present invention, livestock means animals generally raised by humans. In addition to animals raised in farms and ordinary households, experimental animals used for research are also included. For example, dog, cat, horse, pig, cow, monkey, guinea pig, mouse, rat, hamster, rabbit, squirrel, chicken,
Duck, turkey, beetle pine, parakeet, bird, parrot, mynah, and the like.

In the present invention, the term "sugar-derived extract" means an extract obtained by treating a raw material selected from sugar cane juice and molasses derived from cane sugar by column chromatography.

In the present invention, the term "sugar juice" refers to a pressed juice obtained by squeezing sugar cane (sugar cane), a leached juice obtained by leaching sugar cane, or a lime-treated cleanup in the process of a raw sugar manufacturing plant. Juice, concentrated juice, drain water,
In the process of a refined sugar manufacturing plant, it means a resin tower regenerated solution, drain water, or an extract obtained by concentrating and drying an extract extracted with a general-purpose solvent in a plant-derived component extraction method and then re-dissolving in water. . Examples of such an extraction solvent include alcohols such as methanol and ethanol; ketones such as acetone; and acetates such as methyl acetate and ethyl acetate. These may be used alone or in combination. Further, in the case of alcohols and ketones, they may be used in combination with water.

The term "sugar molasses derived from sugar cane" means molasses remaining after removing sugar from sugar cane juice by centrifugation. Molasses waste, and molasses in refined sugar production plants,
Brown liquor, waste sugar honey and the like. In particular, molasses waste and refined molasses refer to molasses remaining after removing most of the sugar from sugar cane juice, and are the parts that can be finally obtained at sugar factories and can no longer be economically recovered. is there.

In the present invention, the extract derived from sugar cane is a deodorant obtained by subjecting a raw material selected from cane juice and molasses derived from cane sugar by column chromatography. The solution is passed through a column filled with a synthetic adsorbent as a fixed carrier, and the components adsorbed on the synthetic adsorbent are fractionated by elution with a solvent selected from water, methanol, ethanol and a mixture thereof. It is preferably a certain deodorant substance.

The deodorant substance is obtained by treating the above sugar cane juice and / or molasses by column chromatography using a fixed carrier. The above sugar cane juice or molasses is treated as it is or adjusted to an arbitrary concentration with water, and treated with a column filled with a fixed carrier. In order to remove foreign substances, it is preferable to filter the sugar cane juice and / or molasses before the treatment with the column. The method of filtration is not particularly limited, screen filtration, diatomaceous earth filtration, which are widely used in the food industry,
Means such as microfiltration and ultrafiltration can be preferably used.

As a fixed carrier, a synthetic adsorbent is used.
As the synthetic adsorbent, preferably, an organic resin can be used. For example, an aromatic resin, an acrylic acid methacrylic resin, an acrylonitrile aliphatic resin, or the like can be used. Aromatic resins are more preferable, and non-substituent type aromatic resins can be particularly used. As a synthetic adsorbent,
For example, an aromatic resin such as a styrene-divinylbenzene resin can be used. Examples of the aromatic resin include an aromatic resin having a hydrophobic substituent, an unsubstituted aromatic resin, and an unsubstituted resin. A porous resin such as an aromatic resin which has been subjected to a special treatment can be used. More preferably, an aromatic resin obtained by subjecting an unsubstituted group to a special treatment can be used. Such synthetic adsorbents are commercially available, for example, HP-10, HP-20, HP-21, H-21 as Diaion ™ systems.
P-30, HP-40, HP-50 (above, unsubstituted aromatic resin, all trade names, manufactured by Mitsubishi Chemical Corporation); SP-825, SP-800, SP-850, S
P-875 (the above is an aromatic resin obtained by subjecting an unsubstituted group to a special treatment, all of which are trade names, manufactured by Mitsubishi Chemical Corporation); S
P-900 (aromatic resin, trade name, manufactured by Mitsubishi Chemical Corporation); Amberlite (trademark) based on XAD-
2, XAD-4, XAD-16, XAD-2000 (above, aromatic resin, all trade names, manufactured by Organo Co., Ltd.);
SP-206, SP-207 (above, aromatic resin having a hydrophobic substituent, both trade names, manufactured by Mitsubishi Chemical Corporation); HP-2MG, EX-0021 (above, an aromatic having a hydrophobic substituent) Group resin, all trade names, manufactured by Mitsubishi Chemical Corporation); Amberlite (trademark) as XA
D-7, XAD-8 (above, acrylic ester resin, all trade names, manufactured by Organo Co., Ltd.); HP1MG, HP2MG (above, acrylic acid methacryl resin, both as commercial products) as Diaion (trademark) LH20 and LH60 (all of which are derivatives of cross-linked dextran, all of which are trade names, manufactured by Pharmacia Biotech Co., Ltd.) as Sephadex (trademark) type. Among them, SP-850 is particularly preferred.

The amount of the fixed carrier varies depending on the size of the column, the type of the solvent, the type of the fixed carrier, and the like. 0.1% based on the solid content of the raw material (selected from cane juice and molasses).
A wet volume of 01 to 5 times is preferred.

Raw materials (selected from cane juice and molasses)
Is passed through the column, the components having a deodorizing effect in the raw material are adsorbed on the fixed carrier, and most of the saccharides flow out and are removed as they are.

The components adsorbed on the fixed carrier are eluted by the solvent. Here, in order to efficiently elute the component having the deodorizing activity, it is preferable that the sugars, salts, and the like remaining before that are sufficiently washed away with water. Thus, the adsorbed target deodorant can be more efficiently collected. The elution solvent is selected from water, methanol, ethanol and a mixture thereof. The elution solvent is preferably a mixed solvent of water and alcohol, particularly a mixed solvent of ethanol and water. Further, the desired deodorant can be efficiently eluted at room temperature, so that 50/50 to 60/40 (vol / vol)
An ethanol-water mixed solvent is preferred. Further, by increasing the column temperature, the ethanol mixture ratio of the ethanol-water mixed solvent can be reduced, and the column temperature is reduced to 50 to 50.
When the temperature is 120 ° C., the target deodorant can be efficiently eluted with only water. In this case, the inside of the column is in a normal pressure or a pressurized state. in this way,
The component having deodorizing activity is present in the fraction eluted with the solvent, but the saccharides (especially sucrose, glucose and fructose) are preferably eluted since the sugar remaining on the column elutes (or elutes) first. Collect the eluted fractions after the fraction that has been subjected to the purification. The elution speed is not particularly limited since it varies depending on the size of the column, the type of the solvent, the type of the fixed carrier, and the like.
^-1 ) is preferred. SV (short for Space Velocity)
Is the space velocity, which is a unit of how many times the resin volume per hour passes.

The above deodorant can be obtained in particular as follows. That is, 0.0 to the solid content of the raw material
After passing the raw material through a column filled with an unsubstituted aromatic resin having a volume of 1 to 5 times the wet volume at a column temperature of 60 to 97 ° C., the components adsorbed on the column are allowed to flow at a column temperature of 20 to 97 ° C.
50/50-60/40 (vol / vol) ethanol at 40 ° C
The fraction is eluted with a water-mixed solvent, and the fraction eluted from the start of elution with the ethanol-water mixed solvent within the 4-fold wet volume of the resin is collected.

The fractions (having deodorizing activity) thus collected are collected and concentrated by conventional means (evaporation of the solvent under reduced pressure, freeze-drying, etc.) to obtain a deodorant substance. The deodorant substance thus obtained has a solid content of 60%
The above concentrated liquid or powder can be stored. The storage is preferably refrigerated, especially in the case of a liquid.

In the deodorant substance, the saccharide content is preferably 50% by weight or less, more preferably 20% by weight or less, particularly preferably 5% by weight or less, based on the solid content.
Here, the saccharide means sucrose, glucose and fructose, and the content of the saccharide means the total content of these. If the content of the saccharide is too large, its use is limited by the sweetness caused by the saccharide. Furthermore, since the ratio of the effective deodorant component in the deodorant is reduced, the deodorant effect on the solid content is reduced. Sugars are usually 0.
Contains 1% by weight or more. The content of sugars in the deodorant treated with the fixed carrier can be detected by high performance liquid chromatography, but may not be detected by thin layer chromatography depending on the concentration of the sugars.

The deodorant can be further purified. For purification, for example, a purification method by chromatography using a fixed carrier and / or a liquid-liquid partitioning method can be used. Examples of the purification method by chromatography using an immobilized carrier include, for example, chromatographic chromatography such as adsorption, distribution, and molecular sieve using a synthetic adsorbent or an ion exchange resin. Examples of the liquid-liquid distribution method include a method using a separating funnel, a method using countercurrent distribution or droplet countercurrent chromatography. The various purification methods can be used in any order and in combination. Each purification method may be repeated multiple times.
Preferably, a combination of chromatography using an immobilized carrier and a liquid-liquid distribution method is performed. Further, a method of purifying by partition type chromatography using an ion exchange resin is preferable.

The etiquette deodorant of the present invention is characterized by containing the above-mentioned extract derived from cane sugar, preferably the above-mentioned deodorant substance, as a component exhibiting a deodorizing effect.

The etiquette deodorant of the present invention may further contain, in addition to the extract derived from sugar cane, optional components such as additives, dispersants, and excipients that do not affect animal health. it can. As additives, dispersants and excipients, for example, sugar,
Various sugars such as lactose and trehalose, various sugar alcohols such as palatinit and lactitol, aspartame,
Various sweeteners such as stevia, various polysaccharides such as dextrin and pullulan, various starches such as corn starch and potato starch, various cellulose derivatives such as carboxymethylcellulose and methylcellulose, various emulsifiers such as glycerin fatty acid ester and sucrose fatty acid ester , Vitamins such as vitamin C, fats and oils such as hardened fats and oils, various natural or synthetic pigments such as safflower pigments, other seasonings, minerals, nutrients, and pharmaceutical departments such as sodium alkyl ether sulfate and lauric acid diethanolamide. Bases and the like commonly used in foreign products are listed.

The etiquette deodorant of the present invention may contain only an extract derived from sugar cane or a mixture containing the extract and any of the above-mentioned additives, dispersants, and excipients. By granulating, tableting, etc., it can be processed into an appropriate shape, water, alcohol, propylene glycol, etc.
It can be processed into a solution using a dissolving agent that does not pose a problem in eating or attaching to the skin. In this manner, the deodorant of the present invention can be obtained by processing the extract derived from the sugar cane.

The shape of the etiquette deodorant of the present invention is not particularly limited, and may be in any form such as solid or liquid, or a mixture of both.

The etiquette deodorant of the present invention is used by applying it to an unpleasant odor source in order to deodorize or reduce the unpleasant odor of the body odor of animals. The source of the unpleasant odor can be part of the animal's body or if it is far from the animal,
For example, it may be an excreted or generated unpleasant odor component.
Means of application include direct application, including, for example, unpleasant odor components (sweat, plaque, various secretions (including excrement, blood, etc.) existing in the unpleasant odor source, and debris from the skin (stain, dander, etc.) ) Etc.), spraying, spraying and the like. Or indirect application, for example, dental care products such as toothpaste, liquid toothpaste, oral ointment, mouthwash, mouthwash tablet; mouth freshener such as gum and candy; spray type antiperspirant, foot odor deodorant Axillary deodorants such as agents; spray-type deodorants for shoes; use as detergents such as soaps and shampoos; or as deodorants added to these. Alternatively, as another method of indirect application, for articles that come into contact with the point where an unpleasant odor occurs in animals, such as clothing, hats, shoes, socks, sanitary products, diapers, bandages, gauze, bandages, etc.
Use as a deodorant for imparting a deodorant component (for example, by application, spraying, spraying, dipping, or the like).

The present invention secondly provides a method for eliminating or reducing an unpleasant odor of body odor of an animal. This deodorizing method is characterized by contacting the above-mentioned extract derived from sugar cane, preferably the above-mentioned deodorant substance, with an unpleasant odor component generated from the animal body. An unpleasant odor component generated from an animal body refers to a component that can be a source of an unpleasant odor of the animal, such as sweat, plaque, various secretions (including excreta and blood, etc.), and exfoliated matter ( (Including dirt, dandruff, etc.). Means of contact include, for example, means of application, spraying, and spraying. Alternatively, it can be used in dental care products such as toothpastes, liquid toothpastes, oral ointments, mouthwashes, mouthwash tablets, etc .; it is used in spray-type antiperspirants such as antiperspirants and foot odors. Used as a spray-type deodorant for shoes; an extract derived from cane sugar can be brought into contact with an unpleasant odor component by a method such as being contained in soap or shampoo and used for washing. In the mouth, the extract derived from sugar cane can be brought into contact with an unpleasant odor component during operations such as chewing gum and licking candy. As another method, articles that come into contact with unpleasant odor components generated from animals, such as clothing, hats, shoes, socks, sanitary products, diapers, bandages, gauze, bandages, etc., contain an extract derived from sugar cane,
Means such as application, spraying, and spraying can also be used. In order to carry out such a use, for example, a cloth such as clothing or socks is impregnated with an extract derived from sugar cane (for example, the cloth is immersed in an aqueous solution in which the extract derived from sugar cane is dissolved). Means can be used.

In the etiquette deodorant and the deodorant method of the present invention, the amount of the extract derived from sugar cane, which is a deodorant component, depends on the degree of purification of the extract derived from sugar cane or the body odor of the target animal. Since it depends on factors such as the location or type difference, weight difference, individual difference, and the like, it cannot be unconditionally determined.
Therefore, it is preferable to add an amount capable of sufficiently effectively and economically eliminating (or reducing) the unpleasant odor of the body odor of the animal.

The etiquette deodorant and the deodorant method of the present invention can be applied to humans.

The present invention will be described in more detail with reference to the following Examples, but it should not be construed that the invention is limited thereto.

[0036]

EXAMPLES In the following, unless otherwise specified,% is:
% By weight.

Production Example 1 Lime-treated clean juice of sugar cane juice obtained in the sugar-making process of a raw sugar production plant (Miyakojima, solid content: 12.1%) 2000
The liter was heated to 80 ° C with a juice heater, and a cartridge filter (made by Advantech Co., Ltd., cotton wind cartridge filter, TCW-100-
(CSD type). 45 liters of a synthetic adsorbent (Sepabeads SP-850; trade name, manufactured by Mitsubishi Chemical Corporation) was packed in a column (column size: 26.0 cm inside diameter, 120 cm height) equipped with a water jacket, and the above-described cleaning agent was added thereto. The juice filtered product was passed at a flow rate of 90 liter / hour (SV = 2.0). During the passage of the clean juice, water at 65 ° C. was constantly circulated in the water jacket. Next, 135 liters of ion-exchanged water was supplied at a flow rate of 90
The column was washed at a rate of 1 / hour (SV = 2.0).

After washing with ion-exchanged water, the fraction eluted from the column was subjected to sugar detection, and a hand-reflex Brix (Bx) meter (Nagoya Atago Co., Ltd., N-1E) was used.
(Type), it was confirmed that Bx was about 0.
Thereafter, a 55% aqueous ethanol solution (ethanol / water = 55/45 (volume / volume)) was used as an elution solvent at a flow rate of 90%.
The solution was passed through the column at liter / hour (SV = 2.0) to elute the components adsorbed on the synthetic adsorbent. During the passage of the elution solvent, water at 25 ° C. was constantly circulated in the water jacket. The fraction eluted with the aqueous ethanol solution was concentrated under reduced pressure using a concentrator, and then lyophilized overnight to obtain 490 g of a brown powder (I).

When the saccharides in the powder (I) were quantified, it was found that
9%.

For quantification of saccharides, the total of sucrose, glucose and fructose was quantified and compared with standard substances (sucrose, glucose and fructose) by an internal standard method using high performance liquid chromatography. The conditions for high performance liquid chromatography were as follows: column ERC-NH-1171 (manufactured by Elma Corporation), flow rate 1.0 ml / min, temperature 20 ° C., solvent acetonitrile:
Water = 80: 20 (volume ratio), detector RI-8010 (manufactured by Tosoh Corporation), internal standard substance glycerin (Wako Pure Chemical Industries, Ltd.), and chroma recorder SC-8020 (tosoh Corporation). .

Example 1 (Breath-Gum after Eating Yakiniku) Using the powder (I) obtained in Production Example 1, chewing gum was prepared according to the formulation shown in Table 1, and after eating yakiniku, A bad breath removal test was performed. The test product was prepared by kneading powdered sugar, powdered glucose, starch syrup, and powder (I) well into a gum base, rolling it with a roll to a uniform thickness, and adding
The product was cut into a size of about 6 cm (about 2 g). For the control, the same amount of powdered sugar was used instead of the powder (I).

[0042]

Table 1 Table 1 Test product Control product Powdered sugar (g) 59.0 60.0 Gum base (g) 20.0 20.0 Glucose powder (g) 10.0 10.0 10.0 Ginger syrup (g) 10.0 10 0.0 powder (I) (g) 1.0- The bad breath removal test after eating the grilled meat was conducted as follows. First, 18 subjects were divided into two groups, (a to
i) and (j to r), the same roasted meat set meal was eaten. One hour after the meal, the breath of each subject was collected in an odor measurement bag (trade name: Flex Sampler (trademark) odor bag, manufactured by Omi Odoair Service Co., Ltd.), and this was regarded as the initial odor.

The group was first given a control chewing gum and after chewing for 3 minutes, the exhaled breath was collected in an odor measurement bag. Subsequently, the chewing gum of the test product was given, and after chewing for 3 minutes, the breath was collected in an odor measurement bag. In addition, the group was given the test product chewing gum first, chewed for 3 minutes, and the exhaled breath was collected in an odor measurement bag. Subsequently, a chewing gum as a control product was given, and after chewing for 3 minutes, the breath was collected in an odor measurement bag. The subjects were not clarified about the difference between the control product and the test product.

The odor collected in this manner was evaluated by three panelists (A to C) who had a nose and shown in Table 2
A sensory test was performed according to the evaluation criteria of each stage. The results are shown in Tables 3 and 4.

[0045]

Table 2 Evaluation stage Evaluation criteria Evaluation criterion 0 Smell that can hardly detect an unpleasant odor compared to the initial odor 1 Smell that can detect a little unpleasant odor compared to the initial odor 2 Initial Smell that can barely perceive an unpleasant odor compared to the odor of 3 Smell that can readily detect an unpleasant odor compared to the initial odor 4 Equivalent odor compared to the initial odor smell

[0046]

[Table 3]

In the group, a sensory test is performed for each breath in which the chewing gum of the control product and then the test product are chewed. From Table 3, it is clear that the chewing gum of the control product alone did not remove much of the bad breath, but the chewing gum of the test product did not remove the bad breath after eating the grilled meat. It is.

[0048]

[Table 4]

In the group, a sensory test is performed for each breath in which the test product is first chewed and then the control product is chewed. From Table 4, it can be seen that the chewing gum of the test product was first used to eliminate the bad breath after eating the grilled meat. However, when the chewing gum of the control product was chewed thereafter, there was no change in the numerical value, indicating that the bad breath was hardly improved.

Example 2 (Breath of breath-candy after smoking) Using the powder (I) obtained in Production Example 1, candy was prepared according to the composition shown in Table 5, and a test for removing bad breath after smoking cigarettes was carried out. Was done. The test product was prepared by dissolving reduced palatinose (trade name: Palatinit, Mitsui Sugar Co., Ltd.) in distilled water, heating to 180 ° C., concentrating (residual water content: about 1%), and cooling to 120 ° C. Acidulant (citric acid, manufactured by Fuso Chemical Industry Co., Ltd.), coloring agent (yellow color TH
-S (safflower colorant), Hasegawa Koryo Co., Ltd.) and powder (I) were added and kneaded well. This was put into a mold so as to be 3 g per candy and molded and manufactured. As a control, the same amount of reduced palatinose was used in place of the powder (I).

[0051]

Table 5 Test product Control product Reduced palatinose (g) 98.3 98.4 Acidulant (g) 0.5 0.5 Colorant (g) 0.1 0.1 Powder (I) (g) 0.1- Distilled water (g) 25.0 25.0 The breath elimination test after smoking was performed as follows. The test subjects (am; healthy men and smokers) first smoked one cigarette (Seven Star) up to 2 cm at the base of the filter. Next, the test subjects (a to h) licked the test sample candy, and the test subjects (i to m) licked the control product candy by two for 5 minutes, and chewed and swallowed them in the next 1 minute. After that, the breath was put into a bag for odor measurement (trade name: Flex Sampler (trademark) odor bag, Omi Odoair Service) and subjected to a sensory test. The sensory test was performed by four panelists according to the five-level evaluation criteria shown in Table 6. Table 7 shows the results.

[0052]

[Table 6] Evaluation stage Evaluation criteria 0 Evaluation odor 0 Almost imperceptible odor 1 Odor sensation that can be detected at last 2 Odor sensation that can be immediately detected 3 Strong disgusting odor 4 Strong disgusting odor

[0053]

[Table 7] Table 7 Evaluation The subjects were (licked test article) (licked control product) a b c d e f g h i j k l m panelists A 1 2 1 1 2 1 1 2 3 4 3 3 3 panelists B 2 1 1 1 2 2 1 1 1 4 4 4 4 4 4 Paneler C 1 1 1 1 1 1 1 1 2 4 4 3 3 4 Paneler D 2 2 2 1 2 1 2 1 3 3 3 4 4 4 Average 1.5 1.5 1.5 1.0 1.8 1.3 1.3 1.5 3.5 3.8 3.3 3.5 3.8 From Table 7, it was found that licking the candy to which the sugarcane-derived extract was added eliminated bad breath after smoking. Example 3 (Bath breath after eating gyoza-mouthwash) Using the powder (I) obtained in Production Example 1, a mouthwash was prepared, and a test for removing bad breath after eating gyoza was performed. The test product was prepared by dissolving 0.2 g of powder (I) in distilled water 1
This was dissolved in 00 ml to produce a mouthwash. As a control, the same amount of distilled water was used instead of the powder (I).

A test for removing bad breath after eating gyoza was performed as follows. The subjects (am) first ate five gyozas with garlic on the market. Next, the subjects (a to h) were asked to wash 60 ml of the above-mentioned test product mouthwash.
The subjects (i to m) gargled five times (60 ml × 5) with 60 ml of the mouthwash of the above-mentioned control product, and then breathed the breath with an odor measurement bag (trade name: Flex Sampler (trademark) odor bag, Omi (Od Air Service) and conducted a sensory test. The sensory test was conducted by four panelists according to Table 8.
The evaluation was performed in accordance with the five-level evaluation criteria shown in Table 1. Table 9 shows the results.

[0055]

[Table 8] Table 8 Evaluation stage Evaluation criteria 0 Smell that can hardly be perceived 1 Smell that can be detected at last 2 Smell that can be immediately detected 3 Strong smell 4 Strong intense smell

[0056]

[Table 9] Table 9 Evaluation The subjects were (gargle test article) (gargle control product) a b c d e f g h i j k l m panelists A 1 1 2 2 2 2 2 1 4 3 4 4 3 panelists B 1 2 1 2 1 2 1 2 4 3 4 4 3 Paneler C 2 2 2 1 2 1 1 1 2 4 4 4 3 4 4 Paneler D 1 1 2 1 2 1 1 1 1 3 3 4 4 4 Average 1.3 1.5 1.8 1.5 1.8 1.5 1.3 1.5 3.8 3.3 3.8 4.0 3.5 From Table 9, it was found that when the mouth was washed with mouthwash to which an extract derived from cane sugar was added, bad breath was removed.

Example 4 (Sweat odor-aerosol) The powder (I) obtained in Production Example 1 was mixed with the components shown in Table 10 to form an aerosol, and hyperhidrosis was found. An axillary odor removal test was performed. As a control, the same amount of distilled water was used instead of the powder (I).

[0058]

Table 10 Test product Control product Ethanol (g) 65.0 65.0 Powder (I) (g) 1.0- Distilled water (g) 34.0 35.0 Hyperhidrotic malodor (armpit odor) The odor removal test was performed as follows. Male subject 6 with hyperhidrotic odor (armpit odor)
Names (A-F) first smelled their own first armpits without doing anything. Next, 1 ml of the aerosol of the control product was sprayed under the armpit using a sprayer, and the axillary odor after the spraying was compared with the initial axillary odor to be judged. Subsequently, 1 ml of the aerosol of the test product was sprayed under the armpit using a sprayer, and the axillary odor was similarly evaluated. The evaluation was performed according to the five-level evaluation criteria shown in Table 11. Table 12 shows the results.

[0059]

[Table 11] Table 11 Evaluation stage Evaluation criteria 0 Smell almost undetectable 1 Smell barely detectable 2 Smell detectable immediately 3 Strong unpleasant smell 4 Strong unpleasant smell

[0060]

[Table 12] Table 12 Evaluation first odor After spraying the control product After spraying the test product Subject A 4 3 1 Subject B 4 4 2 Subject C 4 4 2 Subject D 4 3 1 Subject E 4 4 2 Subject F 4 3 1 It was found that the odor of hyperhidrotic odor (armpit odor) can be suppressed by spraying the aerosol containing the extract.

Example 5 (Foot odor-foot odor preventing sock) Using the powder (I) obtained in Production Example 1, a test for removing foot odor was carried out. First, men's socks were immersed in a 0.05% solution of powder (I) for one hour and dried to produce foot odor preventing socks. The control product was similarly immersed in a men's sock for 1 hour in water instead of the powder (I) and dried.

The test for removing odor from hyperhidrotic odor (foot odor) was conducted as follows. Six male subjects (A to F) having hyperhidrotic malodor (foot odor) had the socks of the test product on their right feet and the socks of the control product on their left feet in the morning. He was asked to judge his own right and left foot odors. The evaluation was performed according to the five-level evaluation criteria shown in Table 13. Table 14 shows the results.

[0063]

[Table 13] Table 13 Evaluation stage Evaluation criteria 0 Smell almost undetectable 1 Smell barely detectable 2 Smell detectable immediately 3 Strong unpleasant smell 4 Strong unpleasant smell

[0064]

[Table 14] Table 14 Evaluation Right foot (sock of test product) Left foot (sock of control product) Subject A 24 Subject B 13 Subject C 24 Subject D 14 Subject E 14 Subject F 24 4 From Table 14, extract from sugar cane was extracted. It was found that the odor of hyperhidrotic odor (foot odor) can be suppressed by wearing the soaked socks.

Example 6 (Body odor-shampoo) Using the powder (I) obtained in Production Example 1, each component was mixed according to the formulation shown in Table 15, a shampoo was prepared, and a body odor removal test was performed. . As a control, the same amount of distilled water was used instead of the powder (I).

[0066]

Table 15 Table 15 Test product Control product Distilled water (g) 78.5 79.5 Sodium alkyl ether sulfate (g) 15.0 15.0 Lauric acid diethanolamide (g) 4.0 4.0 Propylene glycol ( g) 1.5 1.5 Powder (I) (g) 1.0-A test for removing body odor was performed as follows. Two of the same kind,
For puppies A and B (females) of the same age, the body was shampooed once a day for one week continuously using the test shampoo for A and the control shampoo for B in the same manner. After washing, the body odor was directly smelled by the owner and compared.

As a result, the owner reported that puppy A whose body was washed with the shampoo of the test product had less body odor than puppy B whose body was washed with the shampoo of the control product. Was. From the above results, it was found that body odor was suppressed by using the shampoo according to the present invention.

[0068]

EFFECT OF THE INVENTION By using the deodorant or the deodorizing method of the present invention, body odor represented by breath odor, sweat odor, fat odor, physiological odor and the like of an animal can be effectively and simply treated. It can be reduced or deodorized. Moreover, since the extract derived from sugar cane, which is a deodorant component, is derived from plants and has been eaten by humans as a sugar-containing sugar such as brown sugar since ancient times,
Safe and low cost without compromising animal health. Therefore, the deodorant and the deodorizing method of the present invention,
Very useful in industry.

Continued on the front page (51) Int.Cl. ⁶ Identification code FI A61K 7/075 A61K 7/075

Claims (6)

[Claims] 1. An etiquette deodorant applied to an unpleasant odor source to deodorize or reduce an unpleasant odor of body odor of an animal, comprising an extract derived from cane sugar. Agent. 2. The sugar cane-derived extract is a deodorant obtained by subjecting a raw material selected from sugar cane juice and sugar cane-derived molasses by column chromatography, wherein the raw material is a fixed carrier. Is a fraction obtained by passing a liquid through a column filled with a synthetic adsorbent and eluting a component adsorbed by the synthetic adsorbent with a solvent selected from water, methanol, ethanol and a mixture thereof. The etiquette deodorant according to claim 1, which is a deodorant substance. 3. The etiquette deodorant according to claim 1, wherein the unpleasant odor is an odor selected from halitosis, sweat odor, fatty odor and physiological odor. 4. A method for deodorizing or reducing an unpleasant odor of body odor of an animal, the method comprising contacting an extract derived from sugar cane with an unpleasant odor component generated from an animal. 5. A sugar cane-derived extract, which is a deodorant obtained by subjecting a raw material selected from sugar cane juice and sugar cane-derived molasses to column chromatography, wherein the raw material is a fixed carrier. Is a fraction obtained by passing a liquid through a column filled with a synthetic adsorbent and eluting a component adsorbed by the synthetic adsorbent with a solvent selected from water, methanol, ethanol and a mixture thereof. The method according to claim 4, which is a deodorant substance. 6. The method according to claim 4, wherein the unpleasant odor is an odor selected from bad breath, sweat odor, fat odor and physiological odor.