JPH10509740A5 - - Google Patents
Info
- Publication number
- JPH10509740A5 JPH10509740A5 JP1997508693A JP50869397A JPH10509740A5 JP H10509740 A5 JPH10509740 A5 JP H10509740A5 JP 1997508693 A JP1997508693 A JP 1997508693A JP 50869397 A JP50869397 A JP 50869397A JP H10509740 A5 JPH10509740 A5 JP H10509740A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US190195P | 1995-08-04 | 1995-08-04 | |
| US60/001,901 | 1995-08-04 | ||
| US08/693,831 | 1996-07-31 | ||
| US08/693,831 US6017700A (en) | 1995-08-04 | 1996-07-31 | Cationic oligonucleotides, and related methods of synthesis and use |
| PCT/US1996/013056 WO1997006183A1 (en) | 1995-08-04 | 1996-08-01 | Cationic oligonucleotides, and related methods of synthesis and use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007208670A Division JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH10509740A JPH10509740A (ja) | 1998-09-22 |
| JPH10509740A5 true JPH10509740A5 (cg-RX-API-DMAC7.html) | 2004-09-09 |
Family
ID=26669648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9508693A Expired - Lifetime JPH10509740A (ja) | 1995-08-04 | 1996-08-01 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
| JP2007208670A Pending JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007208670A Pending JP2008013571A (ja) | 1995-08-04 | 2007-08-09 | カチオン性オリゴヌクレオチド、ならびに関連の合成および使用の方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6017700A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0785942A1 (cg-RX-API-DMAC7.html) |
| JP (2) | JPH10509740A (cg-RX-API-DMAC7.html) |
| AU (1) | AU702309B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2201963A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO1997006183A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2436857A1 (en) * | 2000-12-14 | 2002-06-20 | Gen-Probe Incorporated | Method and kit for enhancing the association rates of polynucleotides |
| CA2494571C (en) * | 2003-12-02 | 2010-02-09 | F.Hoffmann-La Roche Ag | Oligonucleotides containing molecular rods |
| CN101506368B (zh) * | 2006-07-12 | 2017-02-08 | 加利福尼亚大学董事会 | 通过可逆的磷酸三酯电荷中和保护基转导运输核酸 |
| CN102282155B (zh) | 2008-12-02 | 2017-06-09 | 日本波涛生命科学公司 | 磷原子修饰的核酸的合成方法 |
| BR112012000828A8 (pt) | 2009-07-06 | 2017-10-10 | Ontorii Inc | Novas pró-drogas de ácido nucleico e métodos de uso das mesmas |
| EP2620428B1 (en) | 2010-09-24 | 2019-05-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| CA2834665C (en) * | 2011-05-10 | 2019-08-20 | Bonac Corporation | Process for preparing phosphate compound bearing isotope |
| ES2626488T3 (es) | 2011-07-19 | 2017-07-25 | Wave Life Sciences Pte. Ltd. | Procedimientos para la síntesis de ácidos nucleicos funcionalizados |
| ES2940887T3 (es) * | 2012-07-13 | 2023-05-12 | Wave Life Sciences Ltd | Método de preparación de oligonucleótidos quirales |
| BR112015000723A2 (pt) | 2012-07-13 | 2017-06-27 | Shin Nippon Biomedical Laboratories Ltd | adjuvante de ácido nucléico quiral |
| ES2862073T3 (es) | 2012-07-13 | 2021-10-06 | Wave Life Sciences Ltd | Grupo auxiliar asimétrico |
| CN104781271B (zh) | 2012-08-20 | 2018-07-06 | 加利福尼亚大学董事会 | 具有生物可逆的基团的多核苷酸 |
| EP3013964B1 (en) | 2013-06-28 | 2020-05-06 | ethris GmbH | Compositions for introducing rna into cells |
| US9410172B2 (en) | 2013-09-16 | 2016-08-09 | General Electric Company | Isothermal amplification using oligocation-conjugated primer sequences |
| WO2015108047A1 (ja) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤 |
| JPWO2015108048A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤 |
| US10322173B2 (en) | 2014-01-15 | 2019-06-18 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| CN113278617A (zh) | 2014-01-16 | 2021-08-20 | 波涛生命科学有限公司 | 手性设计 |
| JP2017507946A (ja) | 2014-02-26 | 2017-03-23 | エスリス ゲーエムベーハーｅｔｈｒｉｓ ＧｍｂＨ | Ｒｎａを胃腸内投与するための組成物 |
| EP3034539A1 (en) | 2014-12-19 | 2016-06-22 | Ethris GmbH | Compositions for introducing nucleic acid into cells |
| CA3033867A1 (en) | 2016-08-17 | 2018-02-22 | Solstice Biologics, Ltd. | Polynucleotide constructs |
| WO2018189382A1 (en) | 2017-04-14 | 2018-10-18 | Solstice Biologics, Ltd. | Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use |
| US11597744B2 (en) | 2017-06-30 | 2023-03-07 | Sirius Therapeutics, Inc. | Chiral phosphoramidite auxiliaries and methods of their use |
| JP7256824B2 (ja) | 2018-04-25 | 2023-04-12 | エスリス ゲーエムベーハー | 粒子状製剤用の凍結保護剤 |
| JP2024507394A (ja) | 2021-02-26 | 2024-02-19 | エスリス ゲーエムベーハー | エアロゾル形成用の製剤および核酸を送達するためのエアロゾル |
| AU2022266383A1 (en) * | 2021-04-28 | 2023-11-16 | Japan Science And Technology Agency | Artificial nucleic acid and nucleic acid delivering method using same |
| EP4327829A1 (en) | 2022-08-26 | 2024-02-28 | Ethris GmbH | Stabilization of lipid or lipidoid nanoparticle suspensions |
| JP2025529925A (ja) | 2022-08-26 | 2025-09-09 | エスリス ゲーエムベーハー | 安定な脂質またはリピドイドナノ粒子懸濁液 |
| WO2025045767A1 (en) | 2023-08-25 | 2025-03-06 | Ethris Gmbh | Stabilized lipid and lipidoid nanoparticle formulations with specific surfactant properties for enhanced pharmaceutical applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2586704B1 (fr) * | 1985-09-04 | 1987-12-18 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation et a un groupe chimique activable, leur synthese et leurs applications a titre de nucleases artificielles specifiques de sequences. centre national de la recherche scientifique (cnrs) |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| DE3916871A1 (de) * | 1989-05-24 | 1990-11-29 | Boehringer Mannheim Gmbh | Modifiziertes phosphoramidit-verfahren zur herstellung von modifizierten nukleinsaeuren |
| US4958013A (en) * | 1989-06-06 | 1990-09-18 | Northwestern University | Cholesteryl modified oligonucleotides |
| JPH07501542A (ja) * | 1991-11-25 | 1995-02-16 | ファーマジェニックス，インコーポレーテッド | アミノ炭化水素ホスホン酸塩成分を有するオリゴヌクレオチド |
-
1996
- 1996-07-31 US US08/693,831 patent/US6017700A/en not_active Expired - Lifetime
- 1996-08-01 EP EP96929675A patent/EP0785942A1/en not_active Withdrawn
- 1996-08-01 JP JP9508693A patent/JPH10509740A/ja not_active Expired - Lifetime
- 1996-08-01 WO PCT/US1996/013056 patent/WO1997006183A1/en not_active Ceased
- 1996-08-01 CA CA002201963A patent/CA2201963A1/en not_active Abandoned
- 1996-08-01 AU AU68971/96A patent/AU702309B2/en not_active Ceased
-
2007
- 2007-08-09 JP JP2007208670A patent/JP2008013571A/ja active Pending