JPH10503696A - 収集血液貯蔵パラメータを求めるためのシステム - Google Patents
収集血液貯蔵パラメータを求めるためのシステムInfo
- Publication number
- JPH10503696A JPH10503696A JP9500768A JP50076897A JPH10503696A JP H10503696 A JPH10503696 A JP H10503696A JP 9500768 A JP9500768 A JP 9500768A JP 50076897 A JP50076897 A JP 50076897A JP H10503696 A JPH10503696 A JP H10503696A
- Authority
- JP
- Japan
- Prior art keywords
- plt
- storage
- bag
- platelets
- platelet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/302—Details having a reservoir for withdrawn untreated blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/303—Details having a reservoir for treated blood to be returned
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/30—Single needle dialysis ; Reciprocating systems, alternately withdrawing blood from and returning it to the patient, e.g. single-lumen-needle dialysis or single needle systems for hemofiltration or pheresis
- A61M1/301—Details
- A61M1/305—Control of inversion point between collection and re-infusion phase
- A61M1/308—Volume control, e.g. with open or flexible containers, by counting the number of pump revolutions, weighing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3601—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit
- A61M1/3603—Extra-corporeal circuits in which the blood fluid passes more than once through the treatment unit in the same direction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3624—Level detectors; Level control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
- A61M1/382—Optimisation of blood component yield
- A61M1/385—Optimisation of blood component yield taking into account of the patient characteristics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D17/00—Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
- B01D17/02—Separation of non-miscible liquids
- B01D17/0217—Separation of non-miscible liquids by centrifugal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/24—Feed or discharge mechanisms for settling tanks
- B01D21/2405—Feed mechanisms for settling tanks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/24—Feed or discharge mechanisms for settling tanks
- B01D21/245—Discharge mechanisms for the sediments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/302—Active control mechanisms with external energy, e.g. with solenoid valve
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/30—Control equipment
- B01D21/34—Controlling the feed distribution; Controlling the liquid level ; Control of process parameters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
- B04B7/08—Rotary bowls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0427—Platelets; Thrombocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3344—Measuring or controlling pressure at the body treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3351—Controlling upstream pump pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3355—Controlling downstream pump pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- External Artificial Organs (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. 血液成分についての貯蔵パラメータを推奨するためのシステムであって、 選択された貯蔵基準情報を受け取るためのインプットと、そして、 該選択された貯蔵基準情報に基づいて、使用すべき選択された貯蔵容器の推 奨される個数と使用すべき貯蔵媒質の推奨される量とを含む推奨される貯蔵パラ メータを、出力として発生するための、該インプットに結合させたプロセッサと 、 を含むシステム。 2. 所定のガス透過性容器中においてそして所定の貯蔵媒質と関連して、所定 の血小板数について貯蔵パラメータを推奨するためのシステムであって、 選択された貯蔵基準情報を受け取るためのインプットと、そして、 該選択された貯蔵基準情報に基づいて、使用すべき選択された貯蔵容器の推 奨される個数(Plt BAG)と使用すべき貯蔵媒質の推奨される量(Plt MED)とを 含む推奨される貯蔵パラメータを、出力として発生するための、該インプットに 結合させたプロセッサと、 を含むシステム。 3. 該インプットが受け取る該選択された貯蔵基準情報が、貯蔵すべき血小板 の数を表す値(Yld)とそして貯蔵すべき血小板について測定される平均血小板量( MPV)を表す値(fl)とを含み、そし て 該プロセッサが血小板量(Plt VOL)を次、 PltVol=Yld×MPV のようにして求めるものである、 請求項2のシステム。 4. 該インプットが受け取る該選択された貯蔵基準情報が、選択された容器の ガス透過性を考慮に入れた、選択された容器についての目標血小板量(Plt TVOL )(ml)を含み、そして 該プロセッサが数値BAG、すなわち: を求め、そしてここに、BAG≦1のときPltBAG=1であり、それ以外のと きは、PltBAG=〔BAG+1〕であり、ここに〔BAG+1〕は、量〔BA G+1〕の整数部分である、 請求項3のシステム。 5. 該インプットが受け取る該選択された貯蔵基準情報が、貯蔵の間の血小板 についての、パーセントとして表現された、望みのトロンボサイトクリット(Tc t)を含み、そして 該プロセッサがPlt MED(ml)を次、 のようにして求めるものである、 請求項5のシステム。 6. 所定のガス透過性容器中においてそして所定の貯蔵媒質と関連して、測定 される平均血小板量を有する所定の血小板数について貯蔵パラメータを推奨する ための装置であって、 選択された貯蔵基準情報を受け取るためのインプットであって、 貯蔵すべき血小板の数を表す値(Yld)と、 貯蔵すべき血小板について測定される平均血小板量(MPV)を表す値( fl)と、 選択された容器のガス透過性を考慮に入れた、選択された容器について の目標血小板量(Plt TVOL)(ml)と、そして 貯蔵の間の血小板についての、パーセントとして表現された、望みのト ロンボサイトクリット(Tct)と、 を含む貯蔵基準情報を受け取るためのインプットと、そして これら入力された情報に基づいて、血小板について、使用すべき選択された 貯蔵容器の推奨される個数を表す値(Plt BAG)と使用すべき貯蔵媒質の推奨さ れる量を表す値(Plt MED)とを発生する、該インプットに結合させたプロセッ サと、を含み、 ここに貯蔵すべき血小板の量(Plt VOL)が: PltVol=Yld×MPV であり、ここに数値BAGが: であり、ここに、BAG≦1のときPltBAG=1であり、それ以外のときは、 PltBAG=〔BAG+1〕であり、ここに〔BA G+1〕は、量〔BAG+1〕の整数部分であり、そして ここにPlt MED(ml)が: である、装置。 7. 該選択された貯蔵媒質が重炭酸塩を含み、そして 該インプットが、該選択された貯蔵容器中において該貯蔵媒質中に貯蔵され たときに血小板の酸素分圧を設定された酸素欠乏領域より上に維持するというこ とに、少なくとも部分的に基づいた目標血小板量を受け取るものである、請求項 6の装置。 8. 該選択された貯蔵媒質が血漿を含むものである、請求項7の装置。 9. 貯蔵のために血小板を収集するためのシステムであって、 血液を血漿及び血小板へと分離する分離装置と、 血漿収穫と血小板収穫とに分離するために、血漿と血小板とを含んだ抗凝固 剤添加血液を供血者から該分離装置内へと移送するための該分離装置の入口と、 選択された貯蔵媒質と関連させた選択されたガス透過性貯蔵容器内に貯蔵す るために該血小板収穫の少なくとも一部を収集する間、該血漿収穫の少なくとも 一部を供血者に返還するための該分離装置の第1の出口と、 貯蔵基準情報であって、 該血小板収穫の貯蔵すべき部分を表す値(Yld)と、 貯蔵すべき血小板の測定される平均血小板量を表す値(MP V)(fl)と、 選択された容器のガス透過性を考慮に入れた、選択された容器について の目標血小板量(Plt TVOL)と、 貯蔵の間の血小板についての、パーセントで表した望みのトロンボサイ トクリット(Tct)と、 を含んだ貯蔵基準情報を受け取るためのインプットを含む、該分離装置に結合さ せた処理要素と、を含み 該プロセッサが、これら入力された値に基づいて、血小板について使用すべ き選択された貯蔵容器の個数を表す値(Plt BAG)と貯蔵媒質の推奨される量を 表す値(Plt MED)とを含んだ、推奨される貯蔵パラメータ出力を発生する、該 インプットに結合させた要素を更に含み、 ここに、貯蔵すべき該血小板の量(Plt VOL)(ml)が: PltVol=Yld×MPV であり、ここに数値BAGが: であり、ここに、BAG≦1のときPltBAG=1であり、それ以外のときは、 PltBAG=〔BAG+1〕であり、ここに〔BAG+1〕は、量〔BAG+1 〕の整数部分であり、そして ここにPlt MED(ml)が: である、システム。 10. 貯蔵のため血小板を収集するためのシステムであって、 血液を血漿及び血小板へと分離する分離装置と、 血漿収穫と血小板収穫とに分離するために、血漿と血小板とを含んだ抗凝固 剤添加血液を供血者から該分離装置内へと移送するための該分離装置の入口と、 選択された貯蔵媒質と関連させた選択されたガス透過性貯蔵容器内に貯蔵す るために該血小板収穫の少なくとも一部を収集する間、該血漿収穫の少なくとも 一部を供血者に返還するための該分離装置の第1の出口と、 該分離装置に結合させた処理要素であって、 該分離装置内において分離が行われている間に、貯蔵すべき血小板の収 穫を少なくとも部分的に求める要素と、 貯蔵基準情報を受け取るためのインプットであって、 貯蔵すべき血小板の収穫(Yld)と、 貯蔵すべき血小板の測定される平均血小板量(MPV)を表す値(f l)と、 選択された容器のガス透過性を考慮に入れた、選択された容器につ いての目標血小板量(Plt TVOL)(ml)と、そして 貯蔵の間の血小板についての、パーセントで表された望みのトロン ボサイトクリット(Tct)と、 を含んだ貯蔵基準情報を受け取るためのインプットと、そして 血小板について、使用すべき選択された貯蔵容器の個数を表す値(Plt BAG )と貯蔵媒質の推奨される量を表す値(Plt VOL )とを含む、推奨される貯蔵パラメータ出力を発生するための、該インプットに 結合させたアウトプットと、 を含む処理要素と、を含み ここに、貯蔵すべき該血小板の量(Plt VOL)(ml)が: PltVol=Yld×MPV であり、ここに数値BAGが: であり、ここに、BAG≦1のときPltBAG=1であり、それ以外のときは、 PltBAG=〔BAG+1〕であり、ここに〔BAG+1〕は、量〔BAG+1 〕の整数部分であり、そして ここにPlt MED(ml)が: である、システム。 11. 貯蔵すべき血小板の収穫を決定する要素が、 分離ステップの間に一連の増分期間の間の増分血漿収穫を決定するための手 段と、 各増分期間の間に供血者から採取可能な循環血小板の現在のカウントを推定 するための手段と、 各増分期間についての該決定された増分血漿量に各増分期間についての該推 定された現在の循環血小板のカウントを乗じて各増分期間についての増分血小板 収穫を求めるための手段と、そして 血小板の収穫を求めるために該増分血小板収穫を該一連の増分期間にわたっ て合計するための手段と、 を含むものである、請求項10のシステム。 12. 血液成分についての貯蔵パラメータを推奨するための方法であって、 選択された貯蔵基準情報を入力し、そして 該選択された貯蔵基準情報に基づいて、使用すべき選択された貯蔵容器の推 奨される個数と使用すべき貯蔵媒質の推奨される量とを含む推奨される貯蔵パラ メータを出力として発生すること、 を含む方法。 13. 所定のガス透過性容器中においてそして所定の貯蔵媒質と関連して、所 定の血小板数について貯蔵パラメータを推奨するための方法であって、 選択された貯蔵基準情報を入力として受け取るステップと、そして 該選択された貯蔵基準情報に基づいて、使用すべき選択された貯蔵容器の推 奨される個数(Plt BAG)と使用すべき貯蔵媒質の推奨される量(Plt MED)とを 含む推奨される貯蔵パラメータを、出力として発生するステップと を含む方法。 14. 選択された貯蔵基準情報を受け取る該ステップが、貯蔵すべき血小板の 数を表す値(Yld)とそして貯蔵すべき血小板について測定される平均血小板量(MP V)を表す値(fl)とを含んでおり、そして 該推奨される貯蔵パラメータを発生する該ステップが、血小板 量(Plt VOL)を次、 PltVol=Yld×MPV のようにして計算することを含むものである、 請求項13の方法。 15. 選択された貯蔵基準情報を受け取る該ステップが、貯蔵の間の血小板に ついての、パーセントとして表現された、望みのトロンボサイトクリット(Tct )を受け取ることを含み、そして 推奨される貯蔵パラメータを発生する該ステップが、Plt MED(ml)を次 、 のようにして求めるものである、 請求項13の方法。 16. 該選択された貯蔵基準情報を受け取る該ステップが、選択された容器の ガス透過性を考慮に入れた、選択された容器についての目標血小板量(Plt TVOL )(ml)を受け取ることを含み、そして 該推奨される貯蔵パラメータを発生する該ステップが数値BAG、すなわち : を求めることを含み、そしてここに、BAG≦1のときPltBAG=1であり、 それ以外のときは、PltBAG=〔BAG+1〕で あり、ここに〔BAG+1〕は、量〔BAG+1〕の整数部分である、 請求項13の方法。 17. 選択された貯蔵基準情報を受け取る該ステップが、貯蔵の間の血小板に ついての、パーセントとして表現された、望みのトロンボサイトクリット(Tct )を受け取ることを含み、そして 推奨される貯蔵パラメータを発生する該ステップが、Plt MED(ml)を次 、 のようにして求めるものである、 請求項16の方法。 18. 所定のガス透過性容器中においてそして所定の貯蔵媒質と関連して、測 定される平均血小板量を有する所定の血小板数について貯蔵パラメータを推奨す るための方法であって、 貯蔵すべき血小板の数を表す値(Yld)と;貯蔵すべき血小板について測定さ れる平均血小板量(MPV)を表す値(fl)と;選択された容器のガス透過性を考 慮に入れた、選択された容器についての目標血小板量(Plt TVOL)(ml)と; そして貯蔵の間の血小板についての、パーセントとして表現された、望みのトロ ンボサイトクリット(Tct)と、を含む貯蔵基準情報を受け取るステップと、そ して これら入力された情報に基づいて、血小板について、使用すべき選択された 貯蔵容器の推奨される個数を表す値(Plt BAG)と使 用すべき貯蔵媒質の推奨される量を表す値(Plt MED)とを発生するステップと 、 を含み、ここに、貯蔵すべき血小板の量(Plt VOL)が: PltVol=Yld×MPV として計算され、ここに数値BAGが: として計算され、ここに、BAG≦1のときPltBAG=1であり、それ以外の ときは、PltBAG=〔BAG+1〕であり、ここに〔BAG+1〕は量〔BA G+1〕の整数部分であり、そして ここにPlt MED(ml)が: として計算されるものである、方法。 19. 該選択された貯蔵媒質が重炭酸塩を含み、そして 該目標血小板量が、該選択された貯蔵容器中において該貯蔵媒質中に貯蔵さ れたとき設定された酸素欠乏領域より上に血小板の酸素分圧を維持するというこ とに、少なくとも部分的に基づいているものである、請求項18の方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/483,733 | 1995-06-07 | ||
US08/483,733 US5639382A (en) | 1991-12-23 | 1995-06-07 | Systems and methods for deriving recommended storage parameters for collected blood components |
PCT/US1996/007809 WO1996040405A1 (en) | 1995-06-07 | 1996-05-22 | System for deriving collected blood storage parameters |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH10503696A true JPH10503696A (ja) | 1998-04-07 |
JP3955999B2 JP3955999B2 (ja) | 2007-08-08 |
Family
ID=23921305
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50076897A Expired - Lifetime JP3955999B2 (ja) | 1995-06-07 | 1996-05-22 | 収集血液貯蔵パラメータを求めるためのシステム |
Country Status (9)
Country | Link |
---|---|
US (1) | US5639382A (ja) |
EP (1) | EP0775009B1 (ja) |
JP (1) | JP3955999B2 (ja) |
AU (1) | AU692711B2 (ja) |
CA (1) | CA2195071A1 (ja) |
DE (1) | DE69633768T2 (ja) |
ES (1) | ES2231810T3 (ja) |
NO (1) | NO970542L (ja) |
WO (1) | WO1996040405A1 (ja) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5833866A (en) * | 1991-12-23 | 1998-11-10 | Baxter International Inc. | Blood collection systems and methods which derive instantaneous blood component yield information during blood processing |
US6319471B1 (en) * | 1992-07-10 | 2001-11-20 | Gambro, Inc. | Apparatus for producing blood component products |
US5581687A (en) * | 1994-11-10 | 1996-12-03 | Baxter International Inc. | Interactive control systems for medical processing devices |
US6312607B1 (en) | 1995-06-07 | 2001-11-06 | Baxter International Inc. | Blood processing systems and methods which optically monitor incremental platelet volumes in a plasma constituent |
US5958250A (en) | 1995-06-07 | 1999-09-28 | Baxter International Inc. | Blood processing systems and methods which optically derive the volume of platelets contained in a plasma constituent |
DE69632990T2 (de) * | 1995-06-07 | 2005-07-21 | Baxter International Inc., Deerfield | Blutsammelsystem, das momentan die ausbeute einer komponente berechnet |
JP3941133B2 (ja) * | 1996-07-18 | 2007-07-04 | 富士通株式会社 | 半導体装置およびその製造方法 |
WO1998043720A1 (en) * | 1997-04-03 | 1998-10-08 | Baxter International Inc. | Interface detection and control systems and methods |
US6254784B1 (en) | 1997-10-30 | 2001-07-03 | Baxter International Inc. | Optical interface detection system for centrifugal blood processing |
US6277337B1 (en) | 1998-07-21 | 2001-08-21 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using photosensitizers |
US6258577B1 (en) | 1998-07-21 | 2001-07-10 | Gambro, Inc. | Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers |
JP3817091B2 (ja) * | 1999-07-02 | 2006-08-30 | テルモ株式会社 | 細胞数測定装置 |
US6268120B1 (en) | 1999-10-19 | 2001-07-31 | Gambro, Inc. | Isoalloxazine derivatives to neutralize biological contaminants |
US7072769B2 (en) * | 2000-03-01 | 2006-07-04 | Gambro, Inc. | Extracorporeal blood processing information management system |
US7430478B2 (en) | 2000-03-01 | 2008-09-30 | Caridian Bct, Inc. | Blood processing information system with blood loss equivalency tracking |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
US7211037B2 (en) | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
US7186230B2 (en) * | 2002-03-04 | 2007-03-06 | Therakos, Inc | Method and apparatus for the continuous separation of biological fluids into components |
US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
DE602008005349D1 (de) | 2008-12-29 | 2011-04-14 | Fiat Ricerche | Brennstoffeinspritzsystem mit hoher Betriebswiederholbarkeit und -stabilität für einen Verbrennungsmotor |
WO2012125955A2 (en) | 2011-03-16 | 2012-09-20 | Mayo Foundation For Medical Education And Research | Methods and materials for prolonging useful storage of red blood cell preparations and platelet preparations |
US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
US9440011B2 (en) | 2012-07-12 | 2016-09-13 | Terumo Bct, Inc. | Hybrid blood component storage bag and method of making such bag |
JP6250053B2 (ja) | 2012-09-04 | 2017-12-20 | フェンウォール、インコーポレイテッド | 血液処理システムの境界検知装置 |
US11291931B2 (en) | 2014-12-15 | 2022-04-05 | Akadeum Life Sciences, Inc. | Method and system for buoyant separation |
EP3270307B1 (en) * | 2016-07-13 | 2022-06-22 | Fenwal, Inc. | Cell processing system and method with centralized data management, monitoring and/or control |
US10561784B2 (en) | 2017-05-31 | 2020-02-18 | Fenwal, Inc. | Stationary optical monitoring system for blood processing system |
WO2020014273A1 (en) | 2018-07-09 | 2020-01-16 | Akadeum Life Sciences, Inc. | System and method for buoyant particle processing |
IT201900006867A1 (it) * | 2019-05-15 | 2020-11-15 | Prometheus Soc A Responsabilita Limitata | Metodo e dispositivo di realizzazione di una composizione comprendente plasma arricchito di piastrine, un kit per detto dispositivo di realizzazione, detta composizione stessa e uso di detta composizione |
CA3183013A1 (en) * | 2020-05-13 | 2021-11-18 | Hemanext Inc. | Dehp-free blood storage and methods of use thereof |
US11898967B2 (en) | 2021-02-02 | 2024-02-13 | Fenwal, Inc. | Predicting malfunction and failure of centrifuge umbilicus |
US11819842B2 (en) | 2021-08-26 | 2023-11-21 | Akadeum Life Sciences, Inc. | Method and system for buoyant separation |
Family Cites Families (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3916892A (en) * | 1974-04-29 | 1975-11-04 | Haemonetics Corp | Phlebotomy needle system incorporating means to add anticoagulant and wash liquid |
US3957197A (en) * | 1975-04-25 | 1976-05-18 | The United States Of America As Represented By The United States Energy Research And Development Administration | Centrifuge apparatus |
US4146172A (en) | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
US4187979A (en) * | 1978-09-21 | 1980-02-12 | Baxter Travenol Laboratories, Inc. | Method and system for fractionating a quantity of blood into the components thereof |
US4416654A (en) * | 1981-09-03 | 1983-11-22 | Haemonetics Corporation | Pheresis apparatus |
US4481827A (en) * | 1981-12-15 | 1984-11-13 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collection rate display system |
US4458539A (en) * | 1981-12-15 | 1984-07-10 | Baxter Travenol Laboratories, Inc. | Blood fractionation apparatus having collected volume display system |
US4447191A (en) * | 1981-12-15 | 1984-05-08 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
US4501531A (en) * | 1981-12-15 | 1985-02-26 | Baxter Travenol Laboratories, Inc. | Control circuit for a blood fractionation apparatus |
SE451946B (sv) * | 1982-12-10 | 1987-11-09 | Gambro Lundia Ab | Anordning for avlegsnande av en eller flera fraktioner ur helblod, plasma eller liknande kroppsvetskor |
US5034135A (en) * | 1982-12-13 | 1991-07-23 | William F. McLaughlin | Blood fractionation system and method |
US4537561A (en) * | 1983-02-24 | 1985-08-27 | Medical Technology, Ltd. | Peristaltic infusion pump and disposable cassette for use therewith |
US4540406A (en) * | 1983-05-02 | 1985-09-10 | Thoratec Laboratories Corporation | Anticoagulant delivery system for use with an auto-transfusion system |
FR2548541B1 (fr) * | 1983-07-07 | 1986-09-12 | Rhone Poulenc Sa | Procede de plasmapherese et appareillage utilisable notamment pour ce procede |
FR2548907B1 (fr) * | 1983-07-13 | 1985-11-08 | Rhone Poulenc Sa | Procede de plasmapherese et appareillage utilisable notamment pour ce procede |
DE3584880D1 (de) * | 1984-06-29 | 1992-01-23 | Baxter Int | Verfahren und vorrichtung zum steuern der entnahme und anschliessenden infusion von blut. |
US4573961A (en) * | 1984-10-29 | 1986-03-04 | Extracorporeal Medical Specialties, Inc. | Electronic control methods for puvapheresis apparatus |
US4692138A (en) * | 1984-10-29 | 1987-09-08 | Mcneilab, Inc. | Pump block for interfacing irradiation chamber to photoactivation patient treatment system |
US4879040A (en) * | 1984-11-15 | 1989-11-07 | Baxter International Inc. | Adaptive filter concentrate flow control system and method |
US4713176A (en) * | 1985-04-12 | 1987-12-15 | Hemascience Laboratories, Inc. | Plasmapheresis system and method |
DE3785993T2 (de) | 1986-03-28 | 1994-02-10 | Asahi Medical Co | Filtermedium zur selektiven beseitigung von leucocyten. |
JPS6340532A (ja) * | 1986-04-05 | 1988-02-20 | 日本光電工業株式会社 | 血液成分の監視装置 |
DE3632176A1 (de) * | 1986-09-22 | 1988-04-07 | Fresenius Ag | Steuerung eines systems zur trennung der bestandteile des einem spender "in vivo" entnommenen blutes |
US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
US4883462A (en) * | 1987-01-30 | 1989-11-28 | Baxter Travenol Laboratories, Inc. | Blood extraction assist apparatus and method |
US4769001A (en) * | 1987-02-25 | 1988-09-06 | Baxter International Inc. | Method and apparatus for calibrating plural pump fluid flow system |
US4800492A (en) * | 1987-05-13 | 1989-01-24 | The Coca-Cola Company | Data logger for a post-mix beverage dispensing system |
US4827426A (en) * | 1987-05-18 | 1989-05-02 | The Coca-Cola Company | Data acquisition and processing system for post-mix beverage dispensers |
DE3720665A1 (de) * | 1987-06-23 | 1989-01-05 | Schael Wilfried | Vorrichtung zur haemodialyse und haemofiltration |
US4850995A (en) * | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
US4795314A (en) * | 1987-08-24 | 1989-01-03 | Cobe Laboratories, Inc. | Condition responsive pump control utilizing integrated, commanded, and sensed flowrate signals |
US4867738A (en) * | 1987-09-14 | 1989-09-19 | International Technidyne Corporation | Apparatus and methods for utilizing autotransfusion systems and related equipment |
US4850998A (en) * | 1987-10-07 | 1989-07-25 | Baxter International Inc. | Method for wetting a plasmapheresis filter with anticoagulant |
US5188588A (en) * | 1987-11-25 | 1993-02-23 | Baxter Internatonal Inc. | Single needle continuous hemapheresis apparatus and methods |
US4994188A (en) * | 1988-02-05 | 1991-02-19 | Baxter International Inc. | Adaptive filtrate flow control system using controlled reduction in filter efficiency |
DE3909967A1 (de) * | 1989-03-25 | 1990-09-27 | Fresenius Ag | Haemodialysegeraet mit automatischer einstellung des dialysierfluessigkeitsflusses |
US4995268A (en) * | 1989-09-01 | 1991-02-26 | Ash Medical System, Incorporated | Method and apparatus for determining a rate of flow of blood for an extracorporeal blood therapy instrument |
US5112298A (en) * | 1990-06-25 | 1992-05-12 | Baxter International Inc. | Apheresis method and device |
US5069792A (en) * | 1990-07-10 | 1991-12-03 | Baxter International Inc. | Adaptive filter flow control system and method |
US5234608A (en) * | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
FR2672219B1 (fr) * | 1991-02-06 | 1998-09-11 | Hospal Ind | Procede de commande de la circulation du sang dans un circuit a aiguille unique. |
DE4129639C1 (ja) * | 1991-09-06 | 1993-02-11 | Fresenius Ag, 6380 Bad Homburg, De | |
AU663160B2 (en) | 1991-12-23 | 1995-09-28 | Baxter International Inc. | Centrifuge |
US5421812A (en) * | 1992-03-04 | 1995-06-06 | Cobe Laboratories, Inc. | Method and apparatus for controlling concentrations in tubing system |
US6319471B1 (en) * | 1992-07-10 | 2001-11-20 | Gambro, Inc. | Apparatus for producing blood component products |
US5437624A (en) * | 1993-08-23 | 1995-08-01 | Cobe Laboratories, Inc. | Single needle recirculation system for harvesting blood components |
US5496265A (en) * | 1992-03-04 | 1996-03-05 | Cobe Laboratories, Inc. | Blood component collection system with optimizer |
US5423738A (en) * | 1992-03-13 | 1995-06-13 | Robinson; Thomas C. | Blood pumping and processing system |
US5378227A (en) * | 1992-08-11 | 1995-01-03 | Cobe Laboratories, Inc. | Biological/pharmaceutical method and apparatus for collecting and mixing fluids |
US5427682A (en) * | 1992-09-17 | 1995-06-27 | J. Vogel Premium Water Co. | Water purification and dispensing system |
DE69425966T2 (de) * | 1993-04-27 | 2001-03-29 | Haemonetics Corp | Apheresisgerät |
US5427695A (en) * | 1993-07-26 | 1995-06-27 | Baxter International Inc. | Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate |
US5478479A (en) * | 1994-05-20 | 1995-12-26 | Haemonetics Corporation | Two-stage cell wash process controlled by optical sensor |
-
1995
- 1995-06-07 US US08/483,733 patent/US5639382A/en not_active Expired - Lifetime
-
1996
- 1996-05-22 AU AU59359/96A patent/AU692711B2/en not_active Expired
- 1996-05-22 CA CA002195071A patent/CA2195071A1/en not_active Abandoned
- 1996-05-22 EP EP96916684A patent/EP0775009B1/en not_active Expired - Lifetime
- 1996-05-22 WO PCT/US1996/007809 patent/WO1996040405A1/en active IP Right Grant
- 1996-05-22 JP JP50076897A patent/JP3955999B2/ja not_active Expired - Lifetime
- 1996-05-22 ES ES96916684T patent/ES2231810T3/es not_active Expired - Lifetime
- 1996-05-22 DE DE69633768T patent/DE69633768T2/de not_active Expired - Lifetime
-
1997
- 1997-02-06 NO NO970542A patent/NO970542L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0775009A4 (en) | 2000-05-24 |
AU692711B2 (en) | 1998-06-11 |
JP3955999B2 (ja) | 2007-08-08 |
EP0775009A1 (en) | 1997-05-28 |
WO1996040405A1 (en) | 1996-12-19 |
DE69633768T2 (de) | 2005-10-27 |
ES2231810T3 (es) | 2005-05-16 |
DE69633768D1 (de) | 2004-12-09 |
AU5935996A (en) | 1996-12-30 |
EP0775009B1 (en) | 2004-11-03 |
NO970542L (no) | 1997-04-04 |
US5639382A (en) | 1997-06-17 |
NO970542D0 (no) | 1997-02-06 |
CA2195071A1 (en) | 1996-12-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP4085339B2 (ja) | 見かけのヘマトクリットによって制御される血液処理システム | |
JP3955999B2 (ja) | 収集血液貯蔵パラメータを求めるためのシステム | |
AU701805B2 (en) | Systems and methods for predicting blood processing parameters | |
JP3951143B2 (ja) | クエン酸塩の返還をモニターする血液処理システム | |
JP3994292B2 (ja) | 血小板カウントを推定するためのシステム及び方法 | |
JP4970333B2 (ja) | 瞬間の成分収穫を求める血液収集システム |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20050927 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20051129 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20060620 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060713 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070116 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070201 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20070410 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20070419 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100518 Year of fee payment: 3 |
|
R360 | Written notification for declining of transfer of rights |
Free format text: JAPANESE INTERMEDIATE CODE: R360 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100518 Year of fee payment: 3 |
|
R360 | Written notification for declining of transfer of rights |
Free format text: JAPANESE INTERMEDIATE CODE: R360 |
|
R371 | Transfer withdrawn |
Free format text: JAPANESE INTERMEDIATE CODE: R371 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100518 Year of fee payment: 3 |
|
S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20100518 Year of fee payment: 3 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20110518 Year of fee payment: 4 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120518 Year of fee payment: 5 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130518 Year of fee payment: 6 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
EXPY | Cancellation because of completion of term |