JPH10338636A5 - - Google Patents

Info

Publication number
JPH10338636A5
JPH10338636A5 JP1997163543A JP16354397A JPH10338636A5 JP H10338636 A5 JPH10338636 A5 JP H10338636A5 JP 1997163543 A JP1997163543 A JP 1997163543A JP 16354397 A JP16354397 A JP 16354397A JP H10338636 A5 JPH10338636 A5 JP H10338636A5
Authority
JP
Japan
Prior art keywords
group
carbon atoms
general formula
r4co
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997163543A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10338636A (ja
JP4176170B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority to JP16354397A priority Critical patent/JP4176170B2/ja
Priority claimed from JP16354397A external-priority patent/JP4176170B2/ja
Publication of JPH10338636A publication Critical patent/JPH10338636A/ja
Publication of JPH10338636A5 publication Critical patent/JPH10338636A5/ja
Application granted granted Critical
Publication of JP4176170B2 publication Critical patent/JP4176170B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP16354397A 1997-06-06 1997-06-06 アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬 Expired - Fee Related JP4176170B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16354397A JP4176170B2 (ja) 1997-06-06 1997-06-06 アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16354397A JP4176170B2 (ja) 1997-06-06 1997-06-06 アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬

Publications (3)

Publication Number Publication Date
JPH10338636A JPH10338636A (ja) 1998-12-22
JPH10338636A5 true JPH10338636A5 (enExample) 2005-03-17
JP4176170B2 JP4176170B2 (ja) 2008-11-05

Family

ID=15775896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16354397A Expired - Fee Related JP4176170B2 (ja) 1997-06-06 1997-06-06 アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬

Country Status (1)

Country Link
JP (1) JP4176170B2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3692492B2 (ja) * 2001-05-01 2005-09-07 独立行政法人科学技術振興機構 新規なスフィンゴ脂質合成阻害剤
BR122015016313B8 (pt) * 2001-07-16 2021-05-25 Genzyme Corp composto semelhante à ceramida e método de preparar um composto
EP1811991B1 (en) 2004-11-10 2018-11-07 Genzyme Corporation Treatment of type 2 diabetes using inhibitors of glycosphingolipid synthesis
EP2032134B1 (en) 2006-05-09 2015-06-24 Genzyme Corporation Methods of treating fatty liver disease comprising inhibiting glucosphingolipid synthesis
EP2594562B1 (en) 2007-05-31 2016-07-20 Genzyme Corporation 2-acylaminopropanol-type glucosylceramide synthase inhibitors
WO2009045503A1 (en) 2007-10-05 2009-04-09 Genzyme Corporation Method of treating polycystic kidney diseases with ceramide derivatives
US8389517B2 (en) 2008-07-28 2013-03-05 Genzyme Corporation Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease
CN107935983A (zh) 2008-10-03 2018-04-20 简詹姆公司 2‑酰胺基丙醇型葡糖神经酰胺合酶抑制剂
NZ625712A (en) 2009-11-27 2016-02-26 Genzyme Corp An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
US10227323B2 (en) 2013-09-20 2019-03-12 Biomarin Pharmaceutical Inc. Glucosylceramide synthase inhibitors for the treatment of diseases

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