JPH10316529A - Humectant - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a humectant having remarkable roughened skin-improving effect and excellent in moisture retention, smoothness and anti-sticking property of skin surface by using a specific component derived from soybean as an active ingredient. SOLUTION: This humectant comprises a component obtained by subjecting soybean component to enzymatic treatment. Bean-curd refuse is preferably used as the soybean component. An enzyme having action decomposing soybean cell wall, especially cellulase, hemilase or glucanase is preferably used as the enzyme. The humectant is obtained by adding water to soybean component, reacting the soybean component with the enzyme under active conditions to afford an enzymatically treated mixture and then, deactivating the enzyme. The humectant can be utilized for skin lotion, milk lotion, cream, lotion, essence, pack, bathing agent, foundation, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a humectant obtained by treating a soybean component with an enzyme. The present invention also relates to cosmetics and pharmaceuticals containing the humectant. further,
The invention also relates to a method for producing the humectant.

[0002]

2. Description of the Related Art In recent years, research for keeping skin beautiful has been actively conducted for the purpose of developing new cosmetics.
In particular, dermatological research focusing on the structure and function of the skin has been actively conducted. As the term “fresh” is used when describing young and healthy skin, there is a close relationship between healthy skin condition and skin moisture. Generally, it is said that healthy skin is in a state in which keratin moisture is maintained at 10 to 15%.

[0003] In order to keep the skin healthy and beautiful, various studies have been conducted on the development of moisturizers having the function of adjusting the amount of keratin moisture and preventing dry skin. Today, water-soluble polyhydric alcohol humectants, such as glycerin and propylene glycol, are blended into cosmetics for use. However, when a humectant such as glycerin or propylene glycol is applied to the skin, there is a problem that a noticeable sticky feeling is likely to be generated in a functional aspect. In addition, when these humectants are used under low humidity, there is also a problem that moisture in the skin is taken into the humectant and the skin is dried instead.

[0004] On the other hand, development research is also being conducted on skin cosmetics using soybean-derived components. It has been widely known that soy lecithin has a moisturizing effect.
For this reason, it has been proposed to combine soy lecithin with various components to make cosmetics.

For example, Japanese Patent Application Laid-Open No. 61-251605 discloses a cosmetic product comprising a combination of soluble collagen and soybean lecithin. Also, Japanese Unexamined Patent Application Publication No. 62-2985
No. 09 discloses a cosmetic containing soy lecithin and mucin. Japanese Patent Publication No. 7-110010 discloses a cosmetic product characterized by containing soybean lecithin, mucopolysaccharide and inorganic salts. Japanese Patent Application Laid-Open No. 8-183726 discloses cosmetics containing soybean lecithin, cholesterol, glycerin and the like. Further, JP-A-8-183727 discloses an emulsified cosmetic containing soybean lecithin and polyoxyalkylene diglyceryl ether at a predetermined ratio. These publications disclose the use of soy lecithin, but do not disclose the use of soy components other than lecithin.

[0006] On the other hand, JP-A-63-243013 discloses a humectant containing components other than soybean lecithin. That is, there is described a humectant containing, as an active ingredient, an extract obtained by extracting a component specific to soybean hypocotyl with water, lower alcohol or a mixture thereof. The soybean hypocotyl is the first stem part that occurs below the cotyledon attachment part of soybean. To obtain this, the soybean is germinated, heated and peeled when cotyledons and hypocotyls are formed, and cotyledons and hypocotyls are obtained. Must be separated. Therefore, there is a problem that it takes a long time and effort to obtain an extract by this method.

[0007] Further, a method of obtaining a cosmetic component by causing a microorganism to act on the soy component has been developed. For example, Japanese Patent Application Laid-Open No. 1-102011 describes that a fermentation product obtained by allowing a microorganism belonging to the genus Rhizopus to act on a soybean-containing medium has a moisturizing effect. Further, Japanese Patent Laid-Open No.
Japanese Patent No. 254611 discloses a fermentation product obtained by allowing Neurospora sitophila to act on a soybean-containing medium,
It describes that it has an effect of preventing freckles and rough skin. However, since these methods require the action of microorganisms, the production requires a long time and is not suitable for industrial mass production. Another problem is that it is not easy to store and obtain microorganisms.

[0008]

SUMMARY OF THE INVENTION Under such circumstances,
Gives dry skin sufficient moisture retention without causing sticky feeling especially on the sensory surface, and can keep the water content of the stratum corneum healthy in a low humidity environment for a long time, making it easy There is a need to provide a humectant that can be obtained. An object of the present invention is to develop a new humectant satisfying such conditions. That is, an object of the present invention is to provide a moisturizer derived from soybean which is applied to the skin to impart a moisturizing effect, has an effect of improving rough skin caused by drying, and has no stickiness and excellent sensory characteristics. And

[0009]

The above objects have been achieved by providing a humectant according to the present invention, which comprises a component obtained by enzymatically treating a soy component.
The type of the soybean component used in the humectant of the present invention is not particularly limited as long as it is derived from soybean. There are no particular restrictions on the source, variety, growth status, harvest time, etc. of the soybeans used.However, in order to produce a uniform and reproducible humectant, it is best to use soybeans grown and acquired under certain conditions. preferable.

[0010] As the soybean component used in the present invention, soybean itself, a liquid component from which the solid content of soybean has been removed, a solid component from which the liquid component of soybean has been removed, defatted soybean, and the like can be used. In addition, soymilk and okara obtained by heating and squeezing soybeans can also be used. Further, a composition containing a soybean component derivative obtained by adding a reactive substance to these components can also be used.

In the present invention, it is preferable to use okara as a soybean component. Okara is a pomace by-produced in large quantities in the production process of tofu and soy milk, and has recently been often disposed of because it has not found an effective use. For this reason, if okara can be used according to the present invention, the components of soybean can be more effectively used, and efficient use of resources can be achieved. Also,
Because you can get a large amount of okara at low cost,
If okara is used as a soybean component, the present invention can be economically implemented.

Okara can be manufactured using a manufacturing method known to those skilled in the art, and the manufacturing method is not limited. In general, okara can be prepared by immersing soybeans in water equal to or twice the amount for one day, heating at 80 to 100 ° C. for 20 to 60 minutes, and squeezing in a squeeze bag of nylon or the like. The temperature conditions and the heating time can be appropriately changed, and in the present invention, all okara manufactured with such changes can be used.

The humectant of the present invention can be prepared by subjecting the above-mentioned soybean component to an enzyme treatment. The enzyme used in the enzymatic treatment is selected from protein biocatalysts produced in living cells. In producing the humectant of the present invention, it is preferable to use an enzyme having an activity of decomposing the cell wall of soybean. That is, it is preferable to use an enzyme having an activity of degrading cellulose, hemicellulose, pectic substance, glycopeptide, etc. that form the cell wall.
Specifically, enzymes such as cellulase, hemicellulase and glucanase can be exemplified. One of these enzymes may be used alone, or two or more thereof may be used in combination. The enzyme having cell wall degrading activity used in the present invention may be a commercially available product. For example, an enzyme preparation cell crust (trade name: manufactured by Novo) and an enzyme preparation viscozyme (trade name: manufactured by Novo) can be exemplified.

The conditions for the enzyme treatment are not particularly limited as long as the enzyme activities such as soybean cell wall resolution can be sufficiently exhibited. It is preferable to carry out the reaction at an optimum pH and an optimum temperature of the enzyme for efficiency. Generally pH 4
The temperature is set at room temperature to about 70 ° C. The reaction time is set within a range from several minutes to several days depending on the enzyme concentration, pH and temperature. However, when the reaction is carried out for a long time, it is preferable to take measures to prevent undesirable chemical reactions such as decay of the soybean component.

After performing the enzyme reaction, the enzyme is deactivated. The enzyme can be inactivated by a method well known to those skilled in the art. For example, by heating a mixture containing a soy component and an enzyme at 80 to 90 ° C. for 10 to 15 minutes, the enzyme can be deactivated. The mixture after inactivation of the enzyme has a moisturizing effect even as it is, and thus can be used as a humectant without further performing a separation treatment or the like. However, it is preferable to carry out a purification treatment because it contains substances that do not contribute to the development of the moisturizing effect. For example, a solid content and a liquid content can be separated by pressing or the like. Separation can also be achieved by adjusting the pH to form a precipitate. In addition, filtration,
Solid-liquid separation may be performed by a gradient method or the like, or only the moisturizing active ingredient may be separated by a chromatography method.

The form of the humectant obtained by the above method is not particularly limited. Therefore, the solution may be solidified by adding a gelling agent, dispersed by adding a liquid, or made into a solution by adding a solvent. The powder may be formed by spray drying. further,
It may be in the form of paste or jelly. These forms are appropriately determined according to the purpose of use.

It has been confirmed that the humectant of the present invention exhibits excellent tackiness-improving action and skin roughness-improving action, and maintains good moisturizing property and smoothness on the skin surface. Such an effect is superior to glycerin which is a typical moisturizing component currently used and lecithin which is a moisturizing component derived from soybean. Therefore, the humectant of the present invention can be used effectively when improvement of rough skin, improvement of keratin or protection of skin is required.

The humectant of the present invention can be used in a variety of compositions requiring a moisturizing effect. The amount used should be sufficient to achieve the desired moisturizing effect,
The amount can be appropriately determined by those skilled in the art according to well-known methods.

For example, the humectant of the present invention can be incorporated into cosmetics. Types of cosmetics that can be included include lotions, emulsions, creams, lotions, serums,
Pack, bath salt, foundation, makeup base, lipstick,
Examples include a body odor preventing agent, a deodorant agent, a hair restorer, a hair restorer, a shampoo, a rinse, a toilet soap, a body soap, and the like, but are not limited thereto. Further, the humectant of the present invention can also be blended with pharmaceuticals such as ointments, compresses, and medicinal lip balms. Furthermore, the humectant of the present invention can be widely included in compositions that are applied directly to the skin surface, such as Socktouch (trade name).

Various components can be added to cosmetics and pharmaceuticals containing the humectant of the present invention according to the purpose of use. For example, whitening agents, surfactants, pigments,
Fragrances, pigments, preservatives, fungicides, antioxidants, ultraviolet absorbers, infrared absorbers, collagen, mucopolysaccharides, fluorescent materials, sequestering agents, binders, extenders, anti-inflammatory agents,
Antibiotics, blood circulation promoters, cell activators, and the like can be appropriately added according to the purpose. It can also be combined with other humectants such as lecithin.

The following are specific examples of components that can be used in combination with the humectant of the present invention. As polyhydric alcohols that can be used in combination with the humectant of the present invention, ethylene glycol, polyethylene glycol, propylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, dipropylene glycol, glycerin, diglycol Examples thereof include polyglycerin such as glycerin, triglycerin, and tetraglycerin, glucose, maltose, maltose, sucrose, fructose, xylitol, sorbitol, maltotriose, threitol, and erythritol.

The oily components that can be used in combination with the humectant of the present invention include animal and vegetable oils such as tallow, squalane, olive oil, evening primrose oil, rice bran oil, hydrocarbons, and the like.
Mineral oils such as liquid paraffin, isopropyl myristate, ester oils such as pentaerythritol-tetra-2-ethylhexanoate, methylphenyl silicon,
Silicone oils such as dimethyl silicone, alcohols such as 2-octyldodecanol, 2-decyltetradecanol, oleyl alcohol and cetyl alcohol, fatty acids such as behenic acid, oleic acid and isostearic acid, vitamin A, vitamin B, vitamin D, Vitamin K and derivatives thereof can be exemplified.

As the UV absorber which can be used in combination with the humectant of the present invention, para-aminobenzoic acid,
2-ethoxyethyl paramethoxysilicate, isopropyl paramethoxycinnamate, butylmethoxybenzoylmethane, glyceryl-mono-2-ethylhexanoyl-
Di-paramethoxybenzophenone, dicaroyltrioleate, 2-2-dihydroxy-4-methoxybenzophenone, ethyl-4-pishydroxypropylaminobezoate, 2-ethylhexyl-2-cyano-3,3-
Diphenyl acrylate, ethylhexyl paramethoxycinnamate, 2-ethylhexyl salicylate, glyceryl paraaminobenzoate, homomethyl salicylate, methyl fortaminobenzoate, 2-hydroxy-4-methoxybenzophenone, amyl-para-dimethylaminobenzoate, 2-phenylbenzoimidazole Examples thereof include -5-sulfonic acid and 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid.

As lower alcohols that can be used in combination with the humectant of the present invention, ethyl alcohol,
Examples thereof include propyl alcohol, isopropyl alcohol, butyl alcohol, and isobutyl alcohol.

Examples of the surfactant which can be used in combination with the humectant of the present invention include polyoxyethylene branched alkyl ethers such as polyoxyethylene octyldodecyl alcohol and polyoxyethylene-2-decyltetradecyl alcohol, and polyoxyethylene. Polyoxyethylene alkyl ethers such as oleyl alcohol ether, polyoxyethylene cetyl alcohol ether, sorbitan monooleate, sorbitan monoisostearate, sorbitan esters such as sorbitan monolaurate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan Monoisostearate, polyoxyethylene sorbitan esters such as polyoxyethylene sorbitan monolaurate, glyceryl monooleate, Glycerin fatty acid esters such as lyseryl monostearate and glyceryl monomyristate; polyoxyethylene glycerin fatty acid esters such as polyoxyethylene glyceryl monostearate, polyoxyethylene glyceryl monostearate and polyoxyethylene glyceryl monomyristate; polyoxy Polyoxyethylene hydrogenated castor oil fatty acid esters such as ethylene dihydrocholesterol ether, polyoxyethylene hydrogenated castor oil, polyoxyethylene hydrogenated castor oil isostearate, polyoxyethylene alkyl aryl ethers such as polyoxyethylene octyl phenol ether, glycerol monoisostearate Glycerol ether such as glycerol monomyristate, polyoxyethylene glycerol Nonionic surfactants such as polyoxyethylene glycerol ethers such as isostearate and polyoxyethylene glycerol monomyristate, polyglycerin fatty acid esters such as diglyceryl monostearate, decaglyceryl decaisostearate and diglyceryl diisostearate Agents, salts of potassium, sodium, diethanolamine, triethanolamine, amino acids and the like of higher fatty acids such as myristic acid, stearic acid, barmitic acid, behenic acid, isostearic acid, and oleic acid; the above alkali salts of ether carboxylic acids; N-acyl Anionic surfactants such as salts of amino acids, N-acyl sarcon salts, higher alkyl sulfonates, alkylamine salts, polyamines, amino alcohol fatty acid finite silicone resins, alkyl quaternary amines A cationic surfactant such as a monium salt or an amphoteric surfactant can be exemplified.

Phospholipids that can be used in combination with the humectant of the present invention include diacyl ester type glycerophospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, and phosphatidic acid, sisophosphatidylcholine, lysophosphatidylethanolamine, and lysophosphatidylethanolamine. Monoacyl ester glycerophospholipids such as phosphatidylinositol, naturally occurring lecithin such as egg yolk, and hydrogenated products thereof can be exemplified. Those skilled in the art can appropriately select and use additives other than the above depending on the purpose of use.

[0027]

The present invention will be described in detail below with reference to examples and comparative examples. However, the scope of the present invention is not limited to the specific embodiments described in the examples.

(Example 1) Production of humectant (1) After soaking 1 kg of soybeans in 3 liters of room temperature water for 24 hours, water was added so that the weight becomes 5 times the final initial soybean weight, and 90 ° C. For 40 minutes. Thereafter, the soybeans were wrapped in a nylon squeezing bag (manufactured by Toray) and a nylon dropping bag (manufactured by Toray) and squeezed to remove the liquid component, thereby obtaining okara. To 500 g of the obtained okara, 250 ml of water was added, mixed well with stirring, and the pH was adjusted to 5.0 with 1N hydrochloric acid.
Was adjusted. To this acidic mixture, 0.1% (w / w) of each of an enzyme preparation Celcrust (trade name: manufactured by Novo) and an enzyme preparation viscozyme (trade name: manufactured by Novo) are added and mixed well. After holding for 4 hours, the mixture was kept in a water bath at 90 ° C. for 15 minutes to inactivate the enzyme. Further, 350 ml of a liquid humectant was obtained by centrifugation.

(Example 2) Production of humectant (2) The liquid humectant produced by the method of Example 1 was spray-dried using an L-8 type spray drier (manufactured by Okawara Kakoki Co., Ltd.) to obtain a powder. Moisturizer was obtained. This powdery humectant could be easily dissolved in water and returned to a liquid humectant again.

Example 3 Production of Cosmetics (1) The powdery humectant, hydroxypropylmethylcellulose, ethanol and purified water produced by the method of Example 2 were
A cosmetic serum was produced by stirring and mixing at room temperature at a weight ratio described in the following table.

[0031]

Table 1 Component Parts by weight Powdered moisturizer 1.0 Hydroxypropyl methylcellulose 0.05 Ethanol 3.0 Purified water 95.95

(Examples 4 to 7) Production of cosmetics (2) Powdered humectant produced by the method of Example 2, ethanol,
A cosmetic serum was produced by stirring and mixing polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan oleate, methyl paraben, fragrance and purified water at room temperature at the weight ratios shown in the following table. In addition,
The mixing ratio of the humectant was changed for each of Examples 4 to 7.

[0033]

TABLE 2 Ingredients Parts by weight Powdered humectant (Example 4) 0.01 (Example 5) 0.1 (Example 6) 1.0 (Example 7) 10.0 Ethanol 5.0 Polyoxy Ethylene hydrogenated castor oil 1.0 Polyoxyethylene sorbitan oleate 0.5 Methyl paraben 0.1 Perfume 0.05 Purified water The remainder with the total amount being 100 parts

Examples 8 to 11 Production of cosmetics (3) Vaseline, squalane, liquid paraffin, self-emulsifying monostearic acid, glycerin and butylparaben
The premixed liquid A was prepared by uniformly stirring and mixing at 80 ° C. at the weight ratios described in the following table.

[0035]

TABLE 3 Ingredients Parts by weight Vaseline 1.0 Squalane 5.0 Liquid paraffin 5.0 Self-emulsifying 1.5 -butyl paraben monostearate 0.05

A powdered humectant produced by the method of Example 2,
Premixed liquid B was prepared by uniformly stirring and mixing sodium cetyl sulfate, methylparaben and purified water at 80 ° C. at the weight ratios shown in the following table. In addition, the compounding ratio of the humectant was changed in each of Examples 8 to 11.

[0037]

TABLE 4 Ingredients Parts by weight Powdered humectant (Example 8) 0.01 (Example 9) 0.1 (Example 10) 1.0 (Example 11) 10.0 Sodium cetyl sulfate 0.5 Methyl paraben 0.1 Refined water The remainder with the total amount as 100 parts

The premixed liquid A was added to the premixed liquid B under stirring at 80 ° C. and emulsified and dispersed.
This was cooled down to produce a cosmetic emulsion.

Example 12 Production of Cosmetics (4) Powder was prepared by mixing the powdered humectant produced by the method of Example 2 with the components shown in the following table at a predetermined weight ratio at room temperature. A foundation was manufactured.

[0040]

TABLE 5 Ingredients Parts by weight Powdered moisturizer 1.0 Talc 20.3 Mica 35.0 Karion 5.0 Titanium dioxide 12.0 Titanium mica 3.0 Zinc stearate 1.0 Bengala 1.0 Yellow iron oxide 3.0 Black iron oxide 0.2 Nylon powder 8.0 Squalane 6.0 Octyldodecyl myristate 2.0 Neopentyl glycol diisooctanoate 2.0 Sorbitan monooleate 0.5

Example 13 Production of Cosmetics (5) The liquid humectant produced by the method of Example 1 and the components shown in the following table were mixed by stirring at a predetermined weight ratio at room temperature to obtain a hand. A cream was produced.

[0042]

Ingredients parts by weight liquid humectant 3.0 squalane 20.0 cetyl isooctanoate 8.5 microcrystalline wax 1.0 organically modified viscosity mineral 1.3 POE glycerol triisostearate 0.2 glycerin 10 0.0 Preservatives 0.1 Antioxidants 0.1 Fragrances 0.05 Purified water 55.75

Example 14 Production of Cosmetics (6) A lipstick was prepared by mixing the liquid humectant produced by the method of Example 1 with the components shown in the following table at a predetermined weight ratio at room temperature. A cream was produced.

[0044]

Ingredients parts by weight liquid humectant 0.01 stearic acid 8.0 stearyl alcohol 4.0 butyl stearate 6.0 propylene glycol 5.0 glyceryl monostearate 2.0 potassium hydroxide 0.4 preservative 0.1 Antioxidant 0.1 Fragrance 0.05 Purified water 74.34

Example 15 Production of Cosmetics (7) The powdered humectant produced by the method of Example 2 and the components shown in the following table were stirred and mixed at a predetermined weight ratio at room temperature. Lipstick manufactured.

[Table 8] Ingredients Parts by weight Powdered moisturizer 0.1 Titanium dioxide 5.0 Red 201 No. 0.6 Red 202 No. 1.0 Red No. 223 0.1 Candelilla wax 9.0 Solid paraffin 8.0 Beeswax 5.0 Carnauba wax 5.0 Lanolin 11.0 Castor oil 25.2 Cetyl 2-ethylhexanoate 20.0 Isopropyl myristate 10.0

Example 16 Production of Cosmetics (8) A lipstick was prepared by stirring and mixing the liquid humectant produced by the method of Example 1 and the components shown in the following table at a predetermined weight ratio at room temperature. Was manufactured.

[0047]

TABLE 9 Ingredients Parts by weight Liquid moisturizer 1.0 Fatty acid soap 54.0 Sugar 12.0 Glycerin 11.5 Purified water 20.0 Fragrance 1.3 Dye 0.1 Metal sequestering agent 0.1

Example 17 Manufacture of Cosmetics (9) Hair washing by mixing the liquid humectant produced by the method of Example 1 with the components shown in the following table at a predetermined weight ratio at room temperature. A rinsing liquid was prepared.

[0049]

TABLE 10 Component parts by weight Liquid humectant 3.0 Silicone oil 3.0 Liquid paraffin 1.0 Cetyl alcohol 1.5 Stearyl alcohol 1.0 Stearyl trimethylammonium chloride 0.7 Glycerin 3.0 Fragrance 0.1 Dye 1.0 Preservative 0.1 Purified water 85.6

Example 18 Production of Cosmetics (10) The powdered humectant produced by the method of Example 2 and the components shown in the following table were mixed by stirring at a predetermined weight ratio at room temperature. A bath preparation was produced.

[0051]

[Table 11] Ingredients Parts by weight Powder moisturizer 10.0 Sodium sulfate 50.0 Sodium bicarbonate 20.0 Sodium chloride 20.0

(Example 19) Production of cosmetics (11) Hair was prepared by mixing the liquid humectant produced by the method of Example 1 with the components shown in the following table at a predetermined weight ratio at room temperature. Cleaning agent was manufactured.

[0053]

Table 12 Component Parts by weight Liquid humectant 10.0 Lauryl polyoxyethylene (3) sulfate 30.0 Sodium (30% aqueous solution) Sodium lauryl sulfate (30% aqueous solution) 10.0 Coconut oil fatty acid diethanolamide 4 0.0 Glycerin 1.0 Dye 1.0 Fragrance 0.5 Preservative 0.1 Sequestering agent 0.1 pH adjuster 1.0 Purified water 42.3

Example 20 Production of Pharmaceuticals An ointment was produced by stirring and mixing the liquid humectant produced by the method of Example 1 and the components shown in the following table at a predetermined weight ratio at room temperature. did.

[0055]

Ingredients parts by weight liquid humectant 10.0 oxytetracycline hydrochloride 0.03 hydrocortisone 0.01 microcrystalline wax 9.0 solid paraffin 2.0 beeswax 3.0 petrolatum 5.0 reduced lanolin 5.0 squalane 34 0.0 Hexadecyl adipate 10.0 Propylene glycol 5.0 Glycerin monooleate 3.5 POE (20) Sorbitan monooleate 1.0 Preservative 0.1 Antioxidant 0.1 Purified water 12.26

(Comparative Example 1) Production of comparative humectant A liquid humectant for comparison was obtained by repeating the production method of Example 1 without performing treatment with an enzyme preparation.

Comparative Example 2 Production of Comparative Cosmetics (1) Soy lecithin 0.0 in place of the humectant described in Table 2
Using 1 part by weight, a cosmetic serum for comparison was prepared according to the method described in Examples 4-7.

(Comparative Examples 3 to 5) Production of Comparative Cosmetics (2) In place of the humectant described in Table 2, glycerin was used in a weight ratio described in the following table, and Examples 4 to 7 were used. A cosmetic serum for comparison was prepared according to the method described in (1).

[0059]

Table 14 Comparative Example No. Glycerin parts by weight Comparative Example 3 1.0 Comparative Example 4 5.0 Comparative Example 5 10.0

(Comparative Examples 6 to 8) Production of Comparative Cosmetics (3) The concentration of the humectant in the composition of the premixture B described in Table 4 was set to 0, and the premixture A described in Table 3 was used instead. The following amounts of glycerin were added to prepare a cosmetic emulsion for comparison according to the methods described in Examples 8-11.

[0061]

Table 15 Comparative Example No. Glycerin parts by weight Comparative Example 6 1.0 Comparative Example 7 5.0 Comparative Example 8 10.0

(Test Example 1) Component analysis of humectant The effective component of the humectant produced by the method of Example 1 was analyzed. The protein content was measured by the nitrogen determination method (semi-micro Kjeldahl method), and the sugar content was measured by the Somogy method. The results shown in the following table were obtained.

[0063]

TABLE 16 Ingredients wt% protein 2.19 sugars 3.60

When the composition of the sugar component was analyzed by high performance liquid chromatography, the results shown in the following table were obtained.

[0065]

[Table 17] Sugar component wt% fructose 1.3 galactose 5.7 sucrose 43.4 raffinose 8.5 stachyose 25.4 other 15.7

(Test Example 2) Comparative Test of Cosmetics Using the cosmetics of the present invention of Examples 4 to 11 and the comparative cosmetics of Comparative Examples 1 to 8, a skin roughness improvement effect test, a moisture retention test and a smoothness test described below were carried out. A stickiness and stickiness sensory test was conducted. The method of each test is as described below.

(1) Test for Improvement of Skin Roughness A sample of about 1 g was applied to the left lower leg test site of 20 middle-aged and elderly subjects having rough skin on the lower legs twice a day for 4 weeks. The lower right leg served as a control without the application of the sample. The condition of the skin before and after the start of the test was determined according to the following criteria.

[0068]

[Table 18] By comparing the judgment results of the test site and the control site before and after the test, if the skin dryness is improved by two or more steps (for example, + →-,
++ → − ±) is regarded as “valid”, the case where the signal is improved by one step is “slightly valid”, and the case where there is no change is “invalid”. The test results were indicated by the number of subjects who became “effective” and “slightly effective”.

(2) Moisturizing test In a constant temperature room at 20 ° C, a fixed amount of a sample (2 mg / cm
³ ) was applied to the upper arm of an adult male, and the conductance (unit: micromho) after 10 minutes was measured using an impedance meter (IBS-354: manufactured by IBS).
The higher the conductance, the lower the electrical resistance of the skin and the better the moisture retention on the skin surface.

(3) Sensory test A 1.25 ml / cm ² sample was applied twice daily to the forearm flexion side of 20 subjects complaining of rough skin, dry skin, etc. (morning and evening).
After applying for 3 months each, it was evaluated. The result is smoothness,
For the test items for the feeling of stickiness, the number of respondents who answered, "Skin became smooth" and "moist and moist feeling was felt without stickiness", respectively. The results of each test were as shown in the following table.

[0071]

[Table 19] Moisturizing agent Skin roughness improving effect Moisturizing smoothness Stickiness Comparative Example 1 11 29.0 15 17 Comparative Example 2 13 36.2 17 17 Example 4 14 38.1 20 20 Example 5 14 39.3 19 19 Example 6 16 42.0 18 17 Example 7 17 45.6 17 17 Comparative Example 3 8 21.1 12 13 Comparative Example 4 10 23.6 10 10 Comparative Example 5 11 25.9 10 10 Example 8 16 41.0 19 17 Example 9 16 42.1 18 18 Example 10 18 45.3 18 16 Example 11 19 47.0 18 15 Test Example 6 11 23.0 12 10 Test Example 7 12 24.6 10 7 Test Example 8 13 27.9 77

The same test was conducted on the serum of Example 3 to find that the effect of improving skin roughness, moisturizing property, smoothness,
All tackiness was good.

[0073]

The humectant of the present invention has a remarkable effect of improving skin roughness, and has extremely excellent moisturizing properties, smoothness and anti-stickiness on the skin surface. For this reason, the humectant of the present invention can be effectively used for various products including cosmetics and pharmaceuticals applied directly to the skin.

Claims (14)

[Claims] 1. A moisturizer comprising a component obtained by enzymatically treating a soy component. 2. The humectant according to claim 1, wherein the soybean component is a component of okara. 3. The humectant according to claim 1, wherein the enzyme has an action of decomposing the soybean cell wall. 4. The humectant according to claim 1, wherein the enzyme is selected from the group consisting of cellulase, hemicellulase and glucanase. 5. A cosmetic comprising the humectant according to claim 1. 6. A lotion, an emulsion, a cream, a lotion, a serum, a pack, a bath salt, a foundation, a makeup base,
Lipstick, body odor preventive, deodorant, hair restorer, hair restorer,
6. The cosmetic of claim 5, wherein the cosmetic is selected from the group consisting of shampoos, rinses, toilet soaps and body soaps. 7. A blood circulation promoting agent, a whitening agent, a surfactant, a pigment,
It further contains an additive selected from the group consisting of fragrances, preservatives, pigments, fungicides, antioxidants, ultraviolet absorbers, infrared absorbers, fluorescent materials, sequestering agents, binders and extenders. 7. The cosmetic product according to claim 5, wherein the cosmetic product is a cosmetic product. 8. A pharmaceutical comprising the humectant according to claim 1. 9. The medicament according to claim 8, which is selected from the group consisting of an ointment, a compress and a medicated lip balm. 10. The medicament according to claim 9, further comprising an additive selected from the group consisting of an anti-inflammatory agent, a blood circulation promoting agent, a cell activator and an antibiotic. 11. A method for producing a humectant, comprising the steps of: adding water to a soybean component, allowing an enzyme to act under active conditions to obtain an enzyme-treated mixture, and deactivating the enzyme. 12. The method according to claim 11, wherein the soybean component is a component of okara. 13. The method according to claim 11, wherein the enzyme has an action of decomposing the soybean cell wall. 14. The humectant according to claim 11, wherein the enzyme is selected from the group consisting of cellulase, hemicellulase and glucanase.