JPH10127254A - Health food for constipation - Google Patents
Health food for constipationInfo
- Publication number
- JPH10127254A JPH10127254A JP8303487A JP30348796A JPH10127254A JP H10127254 A JPH10127254 A JP H10127254A JP 8303487 A JP8303487 A JP 8303487A JP 30348796 A JP30348796 A JP 30348796A JP H10127254 A JPH10127254 A JP H10127254A
- Authority
- JP
- Japan
- Prior art keywords
- constipation
- health food
- extract
- concentrated
- dried
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010010774 Constipation Diseases 0.000 title claims abstract description 54
- 235000013402 health food Nutrition 0.000 title claims abstract description 34
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000011230 binding agent Substances 0.000 claims abstract description 11
- 239000000203 mixture Substances 0.000 claims abstract description 10
- 235000013305 food Nutrition 0.000 claims abstract description 7
- 239000004744 fabric Substances 0.000 claims abstract description 4
- 238000012856 packing Methods 0.000 claims abstract description 4
- 239000000284 extract Substances 0.000 claims description 29
- 235000013372 meat Nutrition 0.000 claims description 17
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 10
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 8
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 6
- 239000011575 calcium Substances 0.000 claims description 6
- 229910052791 calcium Inorganic materials 0.000 claims description 6
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 4
- 239000000835 fiber Substances 0.000 claims description 4
- 239000008101 lactose Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 235000003599 food sweetener Nutrition 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 239000003765 sweetening agent Substances 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- 230000036541 health Effects 0.000 claims description 2
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims 1
- 238000004898 kneading Methods 0.000 claims 1
- 238000000465 moulding Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 35
- 238000002360 preparation method Methods 0.000 abstract description 10
- 241000196324 Embryophyta Species 0.000 abstract description 7
- 244000294947 Tetragonia tetragonoides Species 0.000 abstract 4
- 235000004472 Tetragonia tetragonoides Nutrition 0.000 abstract 4
- 238000000605 extraction Methods 0.000 abstract 4
- 240000005049 Prunus salicina Species 0.000 abstract 3
- 235000009018 li Nutrition 0.000 abstract 3
- 244000018795 Prunus mume Species 0.000 abstract 1
- 235000011158 Prunus mume Nutrition 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 description 24
- 239000003814 drug Substances 0.000 description 18
- 229940079593 drug Drugs 0.000 description 17
- 239000009701 Senna Extract Substances 0.000 description 15
- 210000001035 gastrointestinal tract Anatomy 0.000 description 15
- 239000008141 laxative Substances 0.000 description 14
- 230000006872 improvement Effects 0.000 description 13
- 229940125722 laxative agent Drugs 0.000 description 12
- 230000009471 action Effects 0.000 description 10
- 239000003826 tablet Substances 0.000 description 10
- 230000000968 intestinal effect Effects 0.000 description 9
- 239000008187 granular material Substances 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
- 210000000936 intestine Anatomy 0.000 description 6
- 230000000622 irritating effect Effects 0.000 description 6
- 230000008855 peristalsis Effects 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 235000013361 beverage Nutrition 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000003651 drinking water Substances 0.000 description 5
- 235000020188 drinking water Nutrition 0.000 description 5
- 230000007794 irritation Effects 0.000 description 5
- 210000001156 gastric mucosa Anatomy 0.000 description 4
- 231100000957 no side effect Toxicity 0.000 description 4
- 239000008213 purified water Substances 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- 241001609213 Carassius carassius Species 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 239000002085 irritant Substances 0.000 description 3
- 231100000021 irritant Toxicity 0.000 description 3
- 235000021018 plums Nutrition 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 230000004936 stimulating effect Effects 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 229920000715 Mucilage Polymers 0.000 description 2
- 206010028813 Nausea Diseases 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 208000037656 Respiratory Sounds Diseases 0.000 description 2
- 235000009337 Spinacia oleracea Nutrition 0.000 description 2
- 206010047924 Wheezing Diseases 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 229950001002 cianidanol Drugs 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 239000002274 desiccant Substances 0.000 description 2
- 230000035622 drinking Effects 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 210000004211 gastric acid Anatomy 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 230000002475 laxative effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 230000008693 nausea Effects 0.000 description 2
- 229920001277 pectin Polymers 0.000 description 2
- 235000010987 pectin Nutrition 0.000 description 2
- 239000001814 pectin Substances 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 239000011719 vitamin A Substances 0.000 description 2
- 235000019155 vitamin A Nutrition 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000945534 Hamana Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 102220547770 Inducible T-cell costimulator_A23L_mutation Human genes 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010028817 Nausea and vomiting symptoms Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 241000219315 Spinacia Species 0.000 description 1
- 244000300264 Spinacia oleracea Species 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 210000003736 gastrointestinal content Anatomy 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000007602 hot air drying Methods 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000008991 intestinal motility Effects 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000007932 molded tablet Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 235000021049 nutrient content Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229940124513 senna glycoside Drugs 0.000 description 1
- 229930186851 sennoside Natural products 0.000 description 1
- IPQVTOJGNYVQEO-KGFNBKMBSA-N sennoside A Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=CC2=C1C(=O)C1=C(O)C=C(C(O)=O)C=C1[C@@H]2[C@H]1C2=CC(C(O)=O)=CC(O)=C2C(=O)C2=C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C=CC=C21 IPQVTOJGNYVQEO-KGFNBKMBSA-N 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Preparation Of Fruits And Vegetables (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【0001】[0001]
【産業上の利用分野】本発明は副作用のない生薬利用の
緩和な便秘解消に効果のある健康食品に関するものであ
る。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a health food which is effective in alleviating constipation by utilizing crude drugs without side effects.
【0002】[0002]
【従来の技術】3〜4日以上も便通のない状態を便秘と
いい、腹部が張った感じとか腹痛等の不快な症状に悩ま
されるようになると、治療が必要になってくる。この便
秘を解消するのが下剤で、作用の仕方から、刺激性下剤
と機械的下剤の2種類に大別できる。刺激性下剤は腸の
粘膜を刺激して、腸の運動を活発化し、排便を促す作用
を持ち、これには大腸刺激性と小腸刺激性の下剤があ
る。一般に刺激性下剤は刺激が強く、効果は大である
が、使用し続けると増量しないと効かなくなり、薬に頼
った排便習慣になりやすい(依存性)という欠点があ
る。機械的下剤は腸の内容物(便)に作用して、水分を
集めて便を膨らませて、その刺激によって排便を促す薬
剤で刺激性下剤に比べて、効力は弱く効果の現われるま
でに長時間を要する欠点がある。刺激性下剤と同様に依
存性があるのも欠点である。また、刺激性下剤は腹痛や
悪心・嘔吐、腹鳴といった症状が出やすく、機械的下剤
は喉の渇き、悪心、腹痛、腹部の膨満感、復鳴といった
症状をおこすことがある。さらに、ときに過敏症状をお
こすことがあり、すぐに服用を中止し、医師に相談する
必要があるといった使用上の注意が必要である。刺激性
下剤及び機械的下剤を含めた従来の下剤は、上記のよう
な欠点から使用にあたっては医師、薬剤師の指示にした
がって使用量や使用期間を正確に守る必要があった。2. Description of the Prior Art Constipation refers to a condition in which a person has not been bowed for more than 3 to 4 days, and treatment becomes necessary when he / she suffers from unpleasant symptoms such as a stomach swelling or abdominal pain. Laxatives resolve this constipation, and can be broadly classified into two types, irritative laxatives and mechanical laxatives, depending on the way of action. Irritant laxatives have the effect of stimulating intestinal mucosa, activating intestinal motility and promoting defecation, and include large bowel irritants and small bowel irritants. In general, irritating laxatives are strongly irritating and have a great effect, but have a drawback that they become ineffective unless the dose is increased if they continue to be used, and that they tend to become dependent on medicine (dependency). Mechanical laxatives act on intestinal contents (feces) to collect water, swell and swell, and stimulate irritation by stimulation. There is a disadvantage that requires. Disadvantages are also disadvantageous, as are irritating laxatives. In addition, irritating laxatives tend to cause symptoms such as abdominal pain, nausea / vomiting, and wheezing, and mechanical laxatives may cause thirst, nausea, abdominal pain, abdominal bloating, and ringing. In addition, there are occasions when irritability symptoms occur, and it is necessary to take precautions for use such that it is necessary to immediately stop taking the drug and consult a doctor. Conventional laxatives, including irritative laxatives and mechanical laxatives, must be used in accordance with the instructions of a physician or pharmacist, and the amount and period of use must be accurately maintained due to the above-mentioned drawbacks.
【0003】[0003]
【発明が解決しようとする課題】従来の下剤は効果が鋭
く、その自己コントロ−ルが難しかった。また、使用し
続けると増量しないと効かなくなり、薬に頼った排便習
慣になりやすかった。また、過敏症状に加えて、胃腸症
状の変化に伴う種々の副作用を招来する危険性が高かっ
た。これらの欠点は薬の持つ薬理効果が強くかつ作用部
位が限定されることが原因と考えられる。そこで、出願
人は緩和な薬理作用を持ち、作用部位が限定されず2ヶ
所以上の複数の作用部位に対して効果を発揮する生薬を
2種類以上組み合わせる処方となし従来からの便秘薬の
前記欠点を解消しようとするものである。The conventional laxative has a sharp effect and its self-control is difficult. Also, if you continue to use it, it will not work unless you increase the amount, and it became easy to become a bowel habit that relied on drugs. In addition to the hypersensitivity symptoms, there was a high risk of causing various side effects accompanying changes in gastrointestinal symptoms. These drawbacks are considered to be due to the strong pharmacological effect of the drug and the limited site of action. Therefore, the applicant has a prescription combining two or more types of crude drugs which have a mild pharmacological action, the action site is not limited, and exerts an effect on two or more action sites, and the above-mentioned disadvantages of conventional constipation drugs Is to be solved.
【0004】[0004]
【課題を解決するための手段】上記の欠点を解決する目
的で、漢方生薬、民間伝承薬等を使用して種々実験検討
した結果、ツルナと梅の組合せ処方が最も便秘に適して
いるとの結論を得た。ツルナは英名New Zeala
nd Spinach、学名Tetragon-iaex
pansa Murrであり別名ハマジシャ、ハマナ、
ハマアカザとも言い多年草の海浜植物である。カルシウ
ム、鉄、カリウム等のミネラルやビタミンA、B1、
B2、C等を多く含み、その栄養価もホウレンソウと同
等又はそれ以上と言われている。このツルナ全草を乾燥
し適宜大に截断又は粉砕したものと、梅肉又は梅肉の乾
燥物を適宜の大きさに截断又は粉砕したものを使用す
る。梅はバラ科の果実であり栄養素の含有量は果物中第
一位であり、カルシウム、リン、鉄の含有量及びタンパ
ク質が非常に多いという点が注目されている。梅から作
った梅干しは日本固有の嗜好品で健康食品の代表とい
え、解熱、鎮痛作用があり、クエン酸、コハク酸、リン
ゴ酸、酒石酸などの有機酸が多い為、清涼感があって食
欲を増進し、唾液や胃液の分泌を促進するので健胃薬と
もなる。ツルナ全草乾燥物と乾燥梅肉を上記のように処
理したものを通常は同重量比を土びん等で煎じ、その煎
液を飲下するのであるが、両乾燥物を同重量混合して湯
煎に便利な布袋又は紙袋にパックすると便利であり、又
両乾燥物の混合比は1:1とに限られるものではなく特
に胃腸の弱い者は乾燥梅肉を少し多目に使用してもよ
い。In order to solve the above-mentioned drawbacks, as a result of various experiments and examinations using Chinese herbal medicines, folklore medicines, etc., it was concluded that the combined prescription of Tulna and plum is most suitable for constipation. I got the conclusion. The crane is New Zealand
nd Spinach, scientific name Tetragon-iaex
pansa Murr, aka Hamajisha, Hamana,
It is also a perennial beach plant called Hamaakaza. Minerals such as calcium, iron and potassium and vitamins A, B 1 ,
It contains a large amount of B 2 , C and the like, and its nutritional value is said to be equal to or higher than spinach. A dried and dried plum meat or a dried plum meat is cut or pulverized to an appropriate size. Plum is a fruit of the family Rosaceae, and has the highest nutrient content among fruits. It is noted that calcium, phosphorus, iron content and protein are very high. Umeboshi made from plums is a favorite product unique to Japan and is a representative of health foods.It has antipyretic and analgesic effects, and it has a lot of organic acids such as citric acid, succinic acid, malic acid and tartaric acid, so it has a refreshing feeling and appetite. It promotes the secretion of saliva and gastric juice. The dried material of Tulna whole plant and dried plum meat as above are usually decocted in the same weight ratio in a pot, etc., and the decoction is drunk. It is convenient to pack them in a cloth bag or paper bag which is convenient for hot water bathing, and the mixing ratio of the two dried products is not limited to 1: 1. Good.
【0005】次に、このツルナ全草乾燥物を日本薬局方
の製剤総則(エキス剤)に従って濃縮エキスを製造し、
梅肉又は乾燥梅肉についても同様に濃縮エキスを製造す
る。そしてこの両濃縮エキスの混合物に精製水等の飲料
水を賦形剤として適宜量添加増量飲下し、又は適宜の賦
形剤及び結合剤を添加して錠剤状、又は顆粒状に成型し
飲下する。以上のように本発明は、ツルナ全草乾燥物と
梅肉乾燥物とを截断又は粉砕しこれを混合して直接湯煎
して飲むか、又は適量包装袋に包装(パック剤)して湯
煎し飲み、又は日本薬局方総則(エキス剤)に従って製
造した濃縮エキスを適量混合し水でもって増量(この際
甘味料を添加してもよい)しドリンク形として飲むか、
当該両エキスの混合物に賦形剤及び結合剤を添加して錠
剤状又は顆粒状に製した健康食品とすることにより課題
を解決した。[0005] Next, a concentrated extract is prepared from the dried whole cruciferous plant in accordance with the general rules of preparation (extract) of the Japanese Pharmacopoeia,
A concentrated extract is similarly produced for plum meat or dried plum meat. Drinking water such as purified water is added as an excipient to the mixture of the two concentrated extracts in an appropriate amount, and the mixture is swallowed, or an appropriate excipient and a binder are added to form a tablet or granule, and the mixture is drunk. Down. As described above, the present invention provides a method for cutting or pulverizing dried whole tuna plants and dried plum meat and mixing and mixing them, and then directly boiling them in water or drinking them, or packing them in a suitable amount in a packaging bag (packing agent) and baking them. Drink, or add an appropriate amount of concentrated extract manufactured according to the Japanese Pharmacopoeia General Rules (extract) and increase with water (in this case, a sweetener may be added) and drink as a drink,
The problem was solved by adding excipients and binders to the mixture of the two extracts to obtain tablets or granules of health food.
【0006】[0006]
【実施例1】ツルナ全草をよく水洗いをなし乾燥し細か
く截断又は粉末化したものと、乾燥梅肉を細かく截断又
は粉末化したものを1:1の混合重量比で混合し、容器
又は湯煎可能な紙袋又は布袋に適宜量包装する。量は一
袋20g〜25gが適量で煎液を飲む。又湯煎可能な袋
に包装しない場合は缶等容器に包装し、使用の都度適量
取り出して湯煎し飲んでもよい。前記ツルナ乾燥剤と梅
肉乾燥剤との混合量は普通には1:1として使用する
が、特に胃腸虚弱の者は梅肉乾燥剤を増量してもよく、
二剤の混合比は特別特定しなくともよく、いわゆる生薬
使用であるから副作用等は生じないので体調に合わせて
自由に選べばよい。上記の煎じ飲料として用いられる場
合は、便秘体質といっても軽度の者の使用に適しお茶代
りに飲めば便秘を防止又は緩和する効果がある。[Example 1] A mixture of dried and finely cut or pulverized dried plum meat, which was thoroughly washed with water and thoroughly dried or cut into powdered plum meat, was mixed at a mixing weight ratio of 1: 1. Pack in suitable paper bags or cloth bags as appropriate. The amount is 20 g to 25 g per bag. When not packed in a bag that can be bathed in hot water, it may be packed in a container such as a can, taken out of a suitable amount each time it is used, and bathed in hot water to drink. The mixing amount of the above-mentioned dessicant and plum desiccant is usually used as 1: 1. Particularly, those with gastrointestinal weakness may increase the plum desiccant,
The mixing ratio of the two agents does not need to be particularly specified, and since it is a so-called crude drug use, there are no side effects or the like, so it can be freely selected according to the physical condition. When used as the above-mentioned decoction beverage, constipation constitution is suitable for use by mild persons and drinking tea instead of tea has the effect of preventing or alleviating constipation.
【0007】[0007]
【実施例2】ツルナ全草をよく水洗いし乾燥して細かく
截断又は粉末化し、日本薬局方の製剤総則(エキス剤)
に従って50%の濃縮エキスを製造する。即ちツルナ乾
燥粉末50gに精製水1リットルを加え500mlまで
濃縮した。次に梅肉を使用し日本薬局方の製剤総則(エ
キス剤)に従って50%の濃縮エキスを製造した。ま
た、梅肉エキスはRO装置(Reverse Osmos
is)を用いて50%濃縮梅果汁を製造してもよい。R
O装置は合成膜と高圧の逆浸透圧によって、梅果汁中の
水だけを選択的に除去し、濃縮する最先端の非加熱濃縮
装置である。調整を容易にするために、砂糖を濃縮前処
理として添加後、RO装置で濃縮梅果汁とした。前記ツ
ルナ濃縮エキスと濃縮果汁を1:1の割合で混合・撹拌
して便秘用のエキス原液とした。前記の50%濃縮原液
それぞれ250gを水50lで薄め、これを200ml
缶に分取し248缶を得る。即ち両濃縮原液を等量合わ
せて500gを水50lで増量し、これを200mlを
単位とし、缶包装したドリンク形の便秘用健康食品を得
る。[Example 2] The whole plant of Tulna is thoroughly washed with water, dried and cut into fine pieces or powdered.
To produce a 50% concentrated extract. That is, 1 liter of purified water was added to 50 g of dried turuna powder and concentrated to 500 ml. Then, a 50% concentrated extract was produced using plum meat in accordance with the general rules of preparation (extract) of the Japanese Pharmacopoeia. In addition, the plum meat extract can be obtained from a RO device (Reverse Osmos).
50% concentrated plum juice may be produced using is). R
The O device is a state-of-the-art non-heat concentration device that selectively removes and concentrates only water in plum juice using a synthetic membrane and high reverse osmosis pressure. To facilitate the adjustment, sugar was added as a pretreatment for concentration, and then concentrated plum juice was obtained using a RO apparatus. The concentrated extract of the crucian carp and the concentrated fruit juice were mixed and stirred at a ratio of 1: 1 to obtain an extract stock solution for constipation. Dilute 250 g of each of the above 50% concentrated stock solutions with 50 l of water, and add 200 ml
Dispense into cans to obtain 248 cans. That is, equal amounts of the two concentrated stock solutions are combined, and 500 g is added to 50 l of water, and 200 ml is used as a unit to obtain canned constipation health food in drink form.
【0008】[0008]
【実施例3】ツルナ濃縮50%エキス250gと梅肉エ
キス50%濃縮果汁250gを混合し、更に賦形剤とし
て精製水等飲料に適する水50lで薄めた液200ml
を単位成分量とし、甘味料として砂糖又は乳糖又は蜂蜜
等の1又は2又は3を適宜量添加してなるドリンク形態
の便秘有効な健康食品とした。Example 3 A mixture of 250 g of a 50% concentrated extract of Tulna and 250 g of a 50% concentrated juice of a plum meat extract, and 200 ml of a liquid diluted with 50 l of water suitable for beverages such as purified water as an excipient
Is a unit component amount, and a constipation effective health food in the form of a drink is prepared by adding 1 or 2 or 3 of sugar, lactose or honey as a sweetener in an appropriate amount.
【0009】[0009]
【実施例4】ツルナ濃縮50%エキス250gと梅肉エ
キス50%濃縮果汁250gとを成形錠剤248粒の単
位成分量として混合し、これを温熱乾燥又は温風乾燥又
は凍結乾燥等により乾燥し粉末となし、これに賦形剤と
してカルシウム及び乳糖を添加し、更に結合剤として澱
粉又はリンゴ繊維の1又は2を適量添加して錠剤状又は
顆粒状に成形する。EXAMPLE 4 250 g of a 50% concentrated extract of Tulna and 250 g of a 50% concentrated juice of plum meat extract were mixed as a unit component amount of 248 molded tablets, and dried by warm drying, hot air drying or freeze drying to obtain a powder. Then, calcium and lactose are added as excipients, and 1 or 2 of starch or apple fiber is added as a binder in an appropriate amount to form tablets or granules.
【0010】[0010]
【発明の作用】ツルナに含まれる植物性粘質物は胃粘膜
を緩和に刺激して腸の蠕動運動の始動を補助したのち、
大腸粘膜を緩和に刺激して腸の蠕動運動を補助する。ま
た、腸管内の水分を吸収して便量の増加と軟便化を促
し、便が大腸内をスム−スに通過するのを助ける。さら
に粘質物が穏やかに胃腸管をコ−ティングすることによ
って胃粘膜を保護し胃に対する過剰な刺激を緩和し、且
つ胃酸の過剰分泌を抑制することによって腸管の過剰な
刺激を緩和する。腸管での脂肪の吸収を抑制して便をや
わらかくして腸管内の移動を助ける。梅に含まれている
ペクチンは腸内水分の吸収を抑制して便を正常な形にと
どめる作用をもち、カテギン酸は、腸の蠕動運動を盛ん
にし、同時に腸内の殺菌をして、たんぱく質の分解を高
める。これらの作用によって人体生理上胃腸の働きを盛
んにして便の通過をよくする。これらの特徴をもつツル
ナと梅を組合わせることによって個々の作用を緩和に、
しかも的確に現わすことによって副作用も無く、習慣性
(依存性)も伴わずに便秘を解消することができるので
ある。The plant mucilage contained in the crucian carp stimulates the gastric mucosa to relax and assists in the initiation of intestinal peristalsis.
Stimulates the large intestinal mucosa to assist intestinal peristalsis. In addition, it absorbs the water in the intestinal tract and promotes an increase in stool volume and softening of the stool, which helps the stool to smoothly pass through the large intestine. In addition, the mucous protects the gastric mucosa by mildly coating the gastrointestinal tract and alleviates excessive irritation to the stomach, and reduces excessive intestinal irritation by suppressing excessive secretion of gastric acid. Suppresses the absorption of fat in the intestinal tract, softens stool and assists movement in the intestinal tract. Pectin contained in plums has the effect of suppressing intestinal water absorption and keeping stool in a normal shape, and catechinic acid promotes intestinal peristalsis, and at the same time, sterilizes the intestine, resulting in protein. Increase the decomposition. By these actions, the function of the gastrointestinal tract is promoted in human physiology, and the passage of stool is improved. By combining trunas and plums with these characteristics, individual effects are alleviated,
In addition, it is possible to eliminate constipation without any side effects and without habit (dependency) by showing it accurately.
【0011】次に実験例について述べる。50%濃縮ツ
ルナ抽出エキス250gと50%濃縮梅果汁エキス25
0gを計算し精製水を用いて50lの試験飲料水を調整
した。この液を200ml缶に分取し、計248本の試
験飲料水を作成した。この缶飲料水を用いて1錠中にセ
ンナエキス40mg(68センノシド単位)を含有する
従来の緩下剤を対照薬剤として、以下の臨床試験を実施
した。 1.実験対象 3日〜4日以上も便通のない状態の患者20名(男性4
名、女性16名、平均年齢32・5歳)但し、以下の項目
の何れかに該当する患者は対象から除外した。 1)急性腹部疾患を有する患者 2)高齢で生理機能が低下している患者 3)妊婦、妊娠している可能性のある婦人及び授乳婦 4)その他医師が不適当と判断した患者 2.患者の同意 原則として試験開始に先立ち、試験の内容を患者に説明
し、患者の同意を得た。 3.実験方法 被験者を1群10名の2群に分け、1群には本発明中実
施例2に示す便秘用健康食品(飲料)を、またもう1群
には実験対照薬剤であるセンナエキス製剤をそれぞれ1
0日間投与し、14日間の休薬期間をおいてクロスオ−
バ−試験を実施した。 1)服用量・服用方法 1回本発明飲料水1本(200
ml)、センナエキス製剤2錠(センナエキス80m
g)原則として1日1回就寝前の服用とした。 2)実験項目 便秘(自覚症状) 3)診断基準 症状毎に下記の4段階に区分した。 3:症状が強度(たえがたいもの) 2:症状が中等度(かなりあるもの) 1:症状が軽度(少しあるもの) 0:症状の無いもの又は改善したもの) 4)効果判定基準 自覚症状 症状の改善度は原則として下記の基準に従って5段階に
区分して判定した。 著名改善(…):3→0、2→0 中等度改善(…):3→1、1→0 軽度改善(+):3→2、2→1 不変(±):症状に変化の無いもの 悪化(−):症状の悪化したもの 5)安全性 試験実施中に発生した副作用は、下記の3段階に分けて
判定し、副作用の内容を詳細に記録した。 全く副作用なし 軽度副作用を認めるも継続服用可能 重篤な副作用により服用中止 6)自覚症状及び安全性を総合して本発明の有用性につ
いて下記の5段階に区分して判定した。 極めて有用 かなり有用 やや有用 有用と思われない 好ましくない 4.実験結果 本発明便秘用健康食品(飲料)の自覚症状改善度を図1
に示した。本発明ドリンク形便秘用健康食品は10日間
の服用で便秘症状に対して著名改善55%、中等度改善
以上75%、軽度改善以上では87%の良好な効果を示
した。対照薬剤であるセンナエキス顆粒も本発明健康食
品とほぼ同等の改善効果を示したが、僅かに及ばなかっ
た。自覚症状(便秘)強度変化を継時的に評価・検討し
た結果を図2に示した。本発明便秘用健康食品(飲料)
は緩徐で持続的な症状改善効果を示したのに対して、セ
ンナエキス製剤は服用開始直後のシャ−プな効果を発現
したが、服用5日目前後から効果が軽減し、服用9日〜
10日目では同容量の服用では効果の低下が明確になっ
た。この傾向は前半及び後半の各10日間の服用期間中
に同様に認められた。14日間の休薬期間をはさんで前
半10日間、後半10日間の計20日間の服用期間中に
悪心、嘔吐、腹鳴、腹部膨満腹感等の副作用がセンナエ
キス顆粒を服用した患者に認められたが、本発明食品の
服用では全く副作用症状は発現しなかった。(図3)参
照。自覚症状と安全性を総合した有用性の判定結果を図
4に示した。本発明食品は極めて有用60%、かなり有
用以上90%、やや有用以上95%でありセンナエキス
の極めて有用30%、かなり有用以上50%、やや有用以
上70%に比較して高い有用性が認められた。以上の結
果から、本発明に係る便秘用健康食品としての飲料はセ
ンナエキスに代表される従来の便秘薬にみられる服容量
を増加しないと効果が現われないといった薬に対する依
存性、習慣性は無く、副作用も全く認められないことか
ら、便秘症状に対する治療及び予防を目的とした健康飲
料として高い評価を得るものと考えられる。Next, an experimental example will be described. 250g of 50% concentrated vine extract and 50% concentrated plum juice extract 25
0 g was calculated and 50 l of test drinking water was prepared using purified water. This liquid was dispensed into 200 ml cans to prepare a total of 248 test drinking waters. Using this canned drinking water, the following clinical test was carried out using a conventional laxative containing 40 mg (68 sennoside units) of Senna extract in one tablet as a control drug. 1. Test subjects 20 patients without bowel movement for more than 3-4 days (4 males)
(16 women, average age 32.5 years) However, patients who corresponded to any of the following items were excluded from the subjects. 1) Patients with acute abdominal disease 2) Elderly patients with poor physiological function 3) Pregnant women, women who may be pregnant and lactating women 4) Other patients judged by doctors to be inappropriate 2. Patient consent In principle, prior to the start of the study, the content of the study was explained to the patient and the patient's consent was obtained. 3. Experimental Method Subjects were divided into two groups of 10 persons per group, one group containing the constipation health food (drink) shown in Example 2 of the present invention, and the other group containing a senna extract preparation as an experimental control drug. 1 each
Administered for 0 days, with a 14-day drug holiday,
A bar test was performed. 1) Dosage / Dose Method One dose of the drinking water of the present invention once (200
ml), Senna extract preparation 2 tablets (Senna extract 80m
g) In principle, once daily before bedtime. 2) Experimental items Constipation (subjective symptoms) 3) Diagnostic criteria Each symptom was classified into the following four stages. 3: Severe symptoms (unbearable) 2: Moderate symptoms (predominant) 1: Slight symptoms (somewhat slight) 0: No symptoms or improvement 4) Effect criteria Symptoms The degree of improvement of symptoms was determined in five stages according to the following criteria in principle. Prominent improvement (…): 3 → 0, 2 → 0 Moderate improvement (…): 3 → 1, 1 → 0 Mild improvement (+): 3 → 2, 2 → 1 Invariant (±): No change in symptoms Things worse (-): worsened symptoms 5) Safety The side effects that occurred during the test were determined in the following three stages, and the details of the side effects were recorded in detail. No side effects were observed. Mild side effects were observed, but continued taking was possible. Administration was discontinued due to serious side effects. 6) Subjective symptoms and safety were comprehensively evaluated to determine the usefulness of the present invention in the following five stages. Extremely useful Very useful Somewhat useful Not considered useful Experimental Results The degree of improvement in subjective symptoms of the constipation health food (drink) of the present invention is shown in FIG.
It was shown to. The drink-type constipation health food of the present invention showed a remarkable 55% improvement in constipation symptoms after taking it for 10 days, a moderate improvement of 75% or more, and a mild improvement of more than 87%. The control drug, Senna extract granules, also showed almost the same improvement effect as the health food of the present invention, but slightly less. FIG. 2 shows the results of successively evaluating and examining changes in the intensity of subjective symptoms (constipation). The present invention constipation health food (beverage)
Showed a slow and sustained symptom improvement effect, whereas the senna extract formulation exhibited a sharp effect immediately after the start of administration, but the effect was reduced from about the fifth day after administration, and from 9 days after administration.
On the 10th day, a decrease in the effect was evident when taking the same dose. This tendency was similarly observed during the first and second 10 days of the dosing period. Adverse effects such as nausea, vomiting, wheezing, and abdominal bloating were observed in patients who took Senna extract granules during the first 10 days and the last 10 days, taking a total of 20 days after the 14-day drug holiday. However, when the food of the present invention was taken, no side effects occurred. See FIG. FIG. 4 shows the results of determining usefulness obtained by integrating the subjective symptoms and safety. The food of the present invention is extremely useful 60%, considerably useful 90%, slightly useful 95%, and has a high usefulness compared to the very useful 30%, fairly useful 50%, slightly useful 70% of Senna extract. Was done. From the above results, the beverage as a health food for constipation according to the present invention does not appear to be effective without increasing the dose seen in conventional constipation drugs represented by senna extract. Since no side effect is observed, it is considered that the beverage is highly evaluated as a health drink for treating and preventing constipation symptoms.
【0012】次に実施例4に示す錠剤状とした本発明便
秘用健康食品についても前記実施例と同様に実験したが
その結果ドリンク状本発明健康食品と略々同様の結果を
得た。但し錠剤状又は顆粒状の本発明健康食品を使用す
る場合は少なくとも大コップ一杯(180ml〜200
ml)の水と共に飲むことが必要である。又煎剤形の本
発明健康食品は、これをお茶代りに常用することによっ
て便秘予防に効果があった。Next, an experiment was carried out on the constipated health food of the present invention in the form of a tablet as shown in Example 4, but as a result, substantially the same results as those of the drink-shaped health food of the present invention were obtained. However, when using the health food of the present invention in the form of tablets or granules, at least one full cup (180 ml to 200 ml) is used.
ml) of water. The health food of the present invention in the form of a decoction was effective in preventing constipation by regularly using it in place of tea.
【0013】[0013]
【発明の効果】便秘解消の要件は、腸の蠕動運動を盛ん
にすると共に胃壁及び腸壁からの水分吸収を抑制して軟
便化を促すことにある。本発明の便秘用健康食品は、そ
の主材がツルナ及び梅肉又はこれらの抽出エキスで、ツ
ルナ抽出液に含まれるカルシウム、鉄、カリウム等のミ
ネラル及びビタミンA、B1、B2、C等のビタミン類等
からなる植物性粘質物は胃粘膜を緩和に刺激して腸の蠕
動運動を補助する効を有する。また、植物性粘質物は腸
管の水分吸収を抑制して便量の増加と軟便化を促す効を
有し、便が大腸内をスム−スに通過するのを助ける。さ
らに粘質物が穏やかに胃腸管をコ−ティングすることに
よって胃粘膜を保護し胃に対する過剰な刺激を緩和し、
且つ胃酸の過剰分泌を抑制することによって腸管の過剰
な刺激を緩和すると共に腸管での脂肪の吸収を抑制して
便をやわらかくして腸管内の移動を助けるという効を有
する。即ちツルナの成分は胃と腸のニヶ所に作用して上
記のような便秘解消の作用と効を併せ有するものであ
る。The requirements for relieving constipation are to promote intestinal peristalsis and to suppress water absorption from the stomach and intestinal walls to promote loose stool. The health food for constipation of the present invention is mainly composed of luna and plum or an extract thereof, and minerals such as calcium, iron and potassium contained in the luna extract and vitamins A, B 1 , B 2 and C etc. Vegetable mucous consisting of vitamins and the like has the effect of stimulating the gastric mucosa in relaxation and assisting intestinal peristalsis. In addition, the vegetable mucilage has the effect of suppressing the absorption of water in the intestinal tract, increasing the amount of stool and promoting loosening, and helps the stool to pass smoothly through the large intestine. In addition, the mucous protects the gastric mucosa by gently coating the gastrointestinal tract and alleviating excessive irritation to the stomach,
In addition, by suppressing excessive secretion of gastric acid, it has the effect of alleviating excessive irritation of the intestinal tract, suppressing absorption of fat in the intestinal tract, softening stool, and assisting movement in the intestinal tract. That is, the component of the crucian carp acts on two places in the stomach and intestine, and has both the above-mentioned action of relieving constipation and the effect.
【0014】次に、梅に含まれるペクチンは腸管の水分
吸収を抑制して便を正常な形にとどめる作用と効を有
し、又梅の含有するカテギン酸は、腸壁(粘膜)に作用
(刺激)してその蠕動運動を旺盛ならしめ、同時に腸内の
殺菌をして、蛋白質の分解を高め、これらの作用によっ
て胃腸の働きを盛んにして便通の効を発揮するのであ
る。Next, pectin contained in ume has an action and an effect of suppressing water absorption in the intestinal tract and keeping stool in a normal form, and catechinic acid contained in ume has an effect on the intestinal wall (mucosa).
It stimulates the peristalsis by stimulating it, and at the same time, sterilizes the intestine, enhances the degradation of proteins, and by these actions, enhances the function of the gastrointestinal tract and exerts the effect of bowel movements.
【0015】次に錠剤状又は顆粒状の本発明便秘用健康
食品は賦形剤及び結合剤を使用するが賦形剤としてのカ
ルシウムは腸内の水分を吸収し乳糖も同様で、乳糖自体
は胃腸から吸収されない性質を有するから腸管内の水分
のみを吸収して便を軟らかくする効を有し、前記のツル
ナや梅の作用と効果をより一層大ならしめ、結合剤とし
ての澱粉は胃腸内では消化吸収されない(澱粉は口腔内
の唾液のみによって消化され腸でもって吸収される栄養
素であるから、錠形・顆粒形として水で飲下すると消化
吸収される状態とはならない。)し、リンゴ繊維と共に
繊維食品として且つ水分で膨大化し便を軟らかくして胃
腸内を通化するから便秘解消の効をより一層大ならしめ
る。Next, the tablet or granular health food for constipation of the present invention uses an excipient and a binder. Calcium as an excipient absorbs water in the intestine and lactose itself. Since it has the property of not being absorbed from the gastrointestinal tract, it has the effect of absorbing only the water in the intestinal tract and softening the stool, further enhancing the action and effect of the above-mentioned luna and plum, and the starch as a binder is (Starch is a nutrient that is digested only by the saliva in the oral cavity and absorbed by the intestine, so that it is not in a state of digestion and absorption when swallowed with water as tablets or granules). As a fiber food along with fiber and swelling with water to soften the stool and pass through the gastrointestinal tract, the effect of relieving constipation is further enhanced.
【0016】以上のように、本発明の便秘用健康食品は
主剤であるツルナ及び梅特有の含有成分が便秘解消に必
須な身体臓器である胃と腸という二ヶ所に緩和に作用す
ると共に、錠剤形・顆粒形としての食品においても主剤
である作用効果に加えて賦形剤及び結合剤において主剤
の作用効果を補完増大ならしめるのでツルナと梅の二剤
採用によって便秘解消に極めて有効な健康食品を提供す
ることができた。As described above, the health food for constipation according to the present invention is a tablet containing not only the main ingredients of trunna and plum but also relaxes the stomach and intestine, which are the body organs essential for relieving constipation. A health food that is extremely effective in relieving constipation by adopting two agents, Tulna and Ume, in addition to the effect of the main agent in foods in the form of granules, in addition to the effect of the main agent in excipients and binders Could be provided.
【0017】ちなみに自覚症状の改善は従来の便秘薬
(センナエキス製剤)に比して図1に示すように効果が
大であり、又便秘症状の経時的強度変化は、図2に示す
ように、本発明におけるドリンク状健康食品と従来市販
のセンナエキス製剤とは顕著な差があり、更に副作用の
発現率においては対比センナエキス製剤が20%〜30
%であるのに対して0%という有効性を示している。従
って総合的にその有効性を観ても図4に示すように本発
明便秘用健康食品は便秘に対して極めて有効である。By the way, the improvement of subjective symptoms is more effective than the conventional constipation drug (senna extract preparation) as shown in FIG. 1, and the temporal change in the intensity of the constipation symptoms is as shown in FIG. However, there is a remarkable difference between the drink-like health food of the present invention and the conventional senna extract preparations on the market.
It shows the effectiveness of 0% against%. Therefore, even if the effectiveness is comprehensively observed, the health food for constipation of the present invention is extremely effective for constipation as shown in FIG.
【図1】本発明便秘用健康食品を使用した場合と従来の
センナエキス製剤を投与した場合との便秘自覚の改善度
比較図である。FIG. 1 is a comparison diagram of the degree of improvement in awareness of constipation when a health food for constipation of the present invention is used and when a conventional senna extract preparation is administered.
【図2】本発明便秘用健康食品を使用した場合と従来の
センナエキス製剤を投与した場との、便秘症状の経時的
強度の変化を示した図である。FIG. 2 is a graph showing the change over time in the intensity of constipation symptoms when the health food for constipation of the present invention is used and when a conventional senna extract preparation is administered.
【図3】本発明便秘用健康食品と従来のセンナエキス製
剤による便秘薬との副作用の発現率比較図である。FIG. 3 is a comparison diagram of the incidence of side effects between the constipation health food of the present invention and a constipation drug using a conventional senna extract preparation.
【図4】本発明便秘用食品と従来の便秘薬センナエキス
の有用性の総合判定図である。FIG. 4 is a diagram for comprehensively determining the usefulness of the constipation food of the present invention and the conventional constipation drug Senna extract.
───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.6 識別記号 FI // A61K 35/78 ACQ A23L 2/00 F ──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. 6 Identification code FI // A61K 35/78 ACQ A23L 2/00 F
Claims (8)
に混合包装してなることを特徴とする便秘用健康食品。1. A health food for constipation, which is obtained by mixing and packing a dried product of tuna and a dried product of plum meat so that it can be roasted in hot water.
ぞれ同重量比混合し、紙袋又は布袋に、湯煎可能なるよ
う包装してなることを特徴とする前記請求項1記載の便
秘用健康食品。2. The health food for constipation according to claim 1, wherein the dried powders of trunna and the dried plum meat are mixed in the same weight ratio and packaged in a paper bag or a cloth bag so as to be roasted in hot water. .
賦形剤と共に混合してなることを特徴とするドリンク形
の便秘用健康食品。3. A constipation health food in the form of a drink, which is obtained by mixing a concentrated extract of trunna and a concentrated extract of plum meat together with an excipient.
%濃縮果汁とをそれぞれ50%重量比混合してなり、更
に賦形剤として水及び適宜量の甘味料を添加してなるこ
とをとを特徴とする前記請求項3記載のドリンク形便秘
用健康食品。4. A 50% concentrated solution of trunna extract and a plum extract 50
4. The constipation health of drink form according to claim 3, characterized in that 50% by weight of the concentrated juice is mixed with each of the concentrated juices, and water and an appropriate amount of a sweetener are added as excipients. Food.
%濃縮液とをそれぞれ50%量混合し、これを乾燥粉末
化し、更に賦形剤及び結合剤を添加混練したる後成型し
てなることを特徴とする錠剤状の便秘用健康食品。5. A 50% concentrated extract of trunna and an extract of plum meat 50.
% Condensed liquid is mixed with each other in an amount of 50%, dried and powdered, and further excipients and binders are added and kneaded, and then molded to produce a tablet-shaped health food for constipation.
濃縮液とをそれぞれ等量混合し、これを乾燥粉末化した
ものに賦形剤及び結合剤を添加混練したる後成型してな
ることを特徴とする顆粒状の便秘用健康食品。6. Concentration of 50% vine extract and 50% ume meat extract
A granular health food for constipation, comprising mixing an equal amount of each of the concentrated liquids with each other, mixing and drying the mixture, adding an excipient and a binder, kneading the mixture, and molding.
剤として澱粉を使用してなることを特徴とする前記請求
項5又は6記載の錠剤状又は顆粒状の便秘用健康食品。7. The tablet or granular health food for constipation according to claim 5, wherein calcium or lactose is used as an excipient and starch is used as a binder.
ゴ繊維を使用してなることを特徴とする前記請求項5又
は6又は7記載の便秘用健康食品。8. The constipation health food according to claim 5, wherein maltose is used as an excipient and apple fiber is used as a binder.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8303487A JP2994594B2 (en) | 1996-10-30 | 1996-10-30 | Health food for constipation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8303487A JP2994594B2 (en) | 1996-10-30 | 1996-10-30 | Health food for constipation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH10127254A true JPH10127254A (en) | 1998-05-19 |
JP2994594B2 JP2994594B2 (en) | 1999-12-27 |
Family
ID=17921554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8303487A Expired - Fee Related JP2994594B2 (en) | 1996-10-30 | 1996-10-30 | Health food for constipation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP2994594B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004052387A1 (en) * | 2002-12-12 | 2004-06-24 | Kt & G Corporation | Crude drug compositions and the process for preparing them |
KR100470819B1 (en) * | 2001-11-01 | 2005-03-07 | 경상남도 | A Japanese Apricot Tablet |
KR100506824B1 (en) * | 2002-12-12 | 2005-08-11 | 주식회사 케이티앤지 | Crude Drug Compositions for treating or preventing intestinal disease and constipation |
JP2013201997A (en) * | 2012-03-29 | 2013-10-07 | Kinki Univ | Method for producing new plum processed product, and functional composition, food composition, and medical composition using the same |
-
1996
- 1996-10-30 JP JP8303487A patent/JP2994594B2/en not_active Expired - Fee Related
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100470819B1 (en) * | 2001-11-01 | 2005-03-07 | 경상남도 | A Japanese Apricot Tablet |
WO2004052387A1 (en) * | 2002-12-12 | 2004-06-24 | Kt & G Corporation | Crude drug compositions and the process for preparing them |
KR100506824B1 (en) * | 2002-12-12 | 2005-08-11 | 주식회사 케이티앤지 | Crude Drug Compositions for treating or preventing intestinal disease and constipation |
JP2013201997A (en) * | 2012-03-29 | 2013-10-07 | Kinki Univ | Method for producing new plum processed product, and functional composition, food composition, and medical composition using the same |
Also Published As
Publication number | Publication date |
---|---|
JP2994594B2 (en) | 1999-12-27 |
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