JPH09501307A - オピオイドレセプター：組成物および方法 - Google Patents

オピオイドレセプター：組成物および方法

Info

Publication number
JPH09501307A
JPH09501307A JP7500850A JP50085094A JPH09501307A JP H09501307 A JPH09501307 A JP H09501307A JP 7500850 A JP7500850 A JP 7500850A JP 50085094 A JP50085094 A JP 50085094A JP H09501307 A JPH09501307 A JP H09501307A
Authority
JP
Japan
Prior art keywords
opioid receptor
receptor
polypeptide
seq
receptor polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7500850A
Other languages
English (en)
Japanese (ja)
Inventor
アイ． ベル，グレイム
レイジーン，テリー
和基 安田
Original Assignee
アーチ ディベロプメント コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アーチ ディベロプメント コーポレイション filed Critical アーチ ディベロプメント コーポレイション
Publication of JPH09501307A publication Critical patent/JPH09501307A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/033—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP7500850A 1993-05-20 1994-05-20 オピオイドレセプター：組成物および方法 Pending JPH09501307A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US6629693A 1993-05-20 1993-05-20
US08/066,296 1993-05-20
US10069493A 1993-07-30 1993-07-30
US08/100,694 1993-07-30
US08/147,592 1993-11-05
US08/147,592 US6096513A (en) 1993-05-20 1993-11-05 Polynucleotides encoding KAPPA opiod receptors
PCT/US1994/005747 WO1994028132A2 (en) 1993-05-20 1994-05-20 Opioid receptors: compositions and methods

Publications (1)

Publication Number Publication Date
JPH09501307A true JPH09501307A (ja) 1997-02-10

Family

ID=27370939

Family Applications (2)

Application Number Title Priority Date Filing Date
JP7500850A Pending JPH09501307A (ja) 1993-05-20 1994-05-20 オピオイドレセプター：組成物および方法
JP2004307483A Withdrawn JP2005124574A (ja) 1993-05-20 2004-10-21 オピオイドレセプター：組成物および方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2004307483A Withdrawn JP2005124574A (ja) 1993-05-20 2004-10-21 オピオイドレセプター：組成物および方法

Country Status (7)

Country Link
US (2) US6096513A (enExample)
EP (1) EP0700438B1 (enExample)
JP (2) JPH09501307A (enExample)
AU (1) AU678266B2 (enExample)
CA (1) CA2163350A1 (enExample)
DE (1) DE69434269T2 (enExample)
WO (1) WO1994028132A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258556B1 (en) * 1993-02-26 2001-07-10 The United States Of America As Represented By The Department Of Health And Human Services cDNA and genomic clones encoding human μ opiate receptor and the purified gene product
US5747279A (en) * 1993-11-05 1998-05-05 Sloan-Kettering Institute For Cancer Research Nucleic acid molecules encoding kappa3 opioid receptors, receptors encoded thereby, and uses thereof
FR2722209B1 (fr) * 1994-07-11 1996-08-14 Univ Pasteur Recepteur opioide kappa humain, acides nucleiques et utilisations
CA2206192A1 (en) 1996-06-13 1997-12-13 F. Hoffmann-La Roche Ag Modulation of lc132 (opioid-like) receptor function
US20030104572A1 (en) * 1997-12-05 2003-06-05 Pasternak Gavril W. Nucleic acid molecules encoding kappa3, opioid receptors, receptors encoded thereby, and uses thereof
WO2000004151A2 (en) * 1998-07-16 2000-01-27 Memorial Sloan-Kettering Cancer Center Identification and characterization of splice variants of kappa3-related opioid receptor (kor3) gene
US6306576B1 (en) * 1999-02-19 2001-10-23 Cleveland Clinic Foundation Diagnostic methods for asthma
EP1537110B1 (en) * 1999-12-06 2007-01-17 Euro-Celtique, S.A. Triazospiro compounds having nociceptin receptor affinity
US7033759B2 (en) * 2000-07-14 2006-04-25 The Rockfeller University Variants of the human kappa opioid receptor gene
WO2005015242A1 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
WO2005045042A1 (ja) * 2003-11-06 2005-05-19 Banyu Pharmaceutical Co., Ltd. サルｏｒｌ１遺伝子及び化合物の評価方法
US20060069086A1 (en) * 2004-09-23 2006-03-30 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US20070110786A1 (en) * 2005-11-15 2007-05-17 Boston Scientific Scimed, Inc. Medical articles having enhanced therapeutic agent binding
WO2010022145A2 (en) * 2008-08-19 2010-02-25 The University Of North Carolina At Chapel Hill Alternatively-spliced isoform of mu-opioid receptor gene with cell excitatory function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508221A1 (en) * 1991-03-28 1992-10-14 American Cyanamid Company Somatostatin receptor
WO1993019086A1 (en) * 1992-03-23 1993-09-30 American Cyanamid Company Purified opioid receptor
AU5012393A (en) * 1992-08-13 1994-03-15 Regents Of The University Of California, The Opioid receptor genes
FR2697850B1 (fr) * 1992-11-10 1994-12-02 Univ Pasteur Nouveaux polypeptides ayant une activité de récepteur opioïde, acides nucléiques codant pour ces polypeptides et utilisations.
EP0612845A3 (en) * 1993-02-26 1994-09-21 American Cyanamid Co Purified opioid receptor.

Also Published As

Publication number Publication date
WO1994028132A3 (en) 1995-05-04
EP0700438B1 (en) 2005-02-09
US6319686B1 (en) 2001-11-20
US6096513A (en) 2000-08-01
EP0700438A1 (en) 1996-03-13
CA2163350A1 (en) 1994-12-08
DE69434269D1 (de) 2005-03-17
AU678266B2 (en) 1997-05-22
JP2005124574A (ja) 2005-05-19
DE69434269T2 (de) 2006-03-30
AU7138294A (en) 1994-12-20
WO1994028132A2 (en) 1994-12-08

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