CA2163350A1 - Opioid receptors: compositions and methods - Google Patents

Opioid receptors: compositions and methods

Info

Publication number
CA2163350A1
CA2163350A1 CA002163350A CA2163350A CA2163350A1 CA 2163350 A1 CA2163350 A1 CA 2163350A1 CA 002163350 A CA002163350 A CA 002163350A CA 2163350 A CA2163350 A CA 2163350A CA 2163350 A1 CA2163350 A1 CA 2163350A1
Authority
CA
Canada
Prior art keywords
opioid receptor
receptor
polypeptide
seq
kappa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002163350A
Other languages
English (en)
French (fr)
Inventor
Graeme I. Bell
Terry Reisine
Kazuki Yasuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arch Development Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2163350A1 publication Critical patent/CA2163350A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/033—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002163350A 1993-05-20 1994-05-20 Opioid receptors: compositions and methods Abandoned CA2163350A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US6629693A 1993-05-20 1993-05-20
US08/066,296 1993-05-20
US10069493A 1993-07-30 1993-07-30
US08/100,694 1993-07-30
US08/147,592 1993-11-05
US08/147,592 US6096513A (en) 1993-05-20 1993-11-05 Polynucleotides encoding KAPPA opiod receptors

Publications (1)

Publication Number Publication Date
CA2163350A1 true CA2163350A1 (en) 1994-12-08

Family

ID=27370939

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002163350A Abandoned CA2163350A1 (en) 1993-05-20 1994-05-20 Opioid receptors: compositions and methods

Country Status (7)

Country Link
US (2) US6096513A (enExample)
EP (1) EP0700438B1 (enExample)
JP (2) JPH09501307A (enExample)
AU (1) AU678266B2 (enExample)
CA (1) CA2163350A1 (enExample)
DE (1) DE69434269T2 (enExample)
WO (1) WO1994028132A2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258556B1 (en) * 1993-02-26 2001-07-10 The United States Of America As Represented By The Department Of Health And Human Services cDNA and genomic clones encoding human μ opiate receptor and the purified gene product
US5747279A (en) * 1993-11-05 1998-05-05 Sloan-Kettering Institute For Cancer Research Nucleic acid molecules encoding kappa3 opioid receptors, receptors encoded thereby, and uses thereof
FR2722209B1 (fr) * 1994-07-11 1996-08-14 Univ Pasteur Recepteur opioide kappa humain, acides nucleiques et utilisations
CA2206192A1 (en) 1996-06-13 1997-12-13 F. Hoffmann-La Roche Ag Modulation of lc132 (opioid-like) receptor function
US20030104572A1 (en) * 1997-12-05 2003-06-05 Pasternak Gavril W. Nucleic acid molecules encoding kappa3, opioid receptors, receptors encoded thereby, and uses thereof
WO2000004151A2 (en) * 1998-07-16 2000-01-27 Memorial Sloan-Kettering Cancer Center Identification and characterization of splice variants of kappa3-related opioid receptor (kor3) gene
US6306576B1 (en) * 1999-02-19 2001-10-23 Cleveland Clinic Foundation Diagnostic methods for asthma
EP1537110B1 (en) * 1999-12-06 2007-01-17 Euro-Celtique, S.A. Triazospiro compounds having nociceptin receptor affinity
US7033759B2 (en) * 2000-07-14 2006-04-25 The Rockfeller University Variants of the human kappa opioid receptor gene
WO2005015242A1 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
WO2005045042A1 (ja) * 2003-11-06 2005-05-19 Banyu Pharmaceutical Co., Ltd. サルｏｒｌ１遺伝子及び化合物の評価方法
US20060069086A1 (en) * 2004-09-23 2006-03-30 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US20070110786A1 (en) * 2005-11-15 2007-05-17 Boston Scientific Scimed, Inc. Medical articles having enhanced therapeutic agent binding
WO2010022145A2 (en) * 2008-08-19 2010-02-25 The University Of North Carolina At Chapel Hill Alternatively-spliced isoform of mu-opioid receptor gene with cell excitatory function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508221A1 (en) * 1991-03-28 1992-10-14 American Cyanamid Company Somatostatin receptor
WO1993019086A1 (en) * 1992-03-23 1993-09-30 American Cyanamid Company Purified opioid receptor
AU5012393A (en) * 1992-08-13 1994-03-15 Regents Of The University Of California, The Opioid receptor genes
FR2697850B1 (fr) * 1992-11-10 1994-12-02 Univ Pasteur Nouveaux polypeptides ayant une activité de récepteur opioïde, acides nucléiques codant pour ces polypeptides et utilisations.
EP0612845A3 (en) * 1993-02-26 1994-09-21 American Cyanamid Co Purified opioid receptor.

Also Published As

Publication number Publication date
WO1994028132A3 (en) 1995-05-04
EP0700438B1 (en) 2005-02-09
US6319686B1 (en) 2001-11-20
JPH09501307A (ja) 1997-02-10
US6096513A (en) 2000-08-01
EP0700438A1 (en) 1996-03-13
DE69434269D1 (de) 2005-03-17
AU678266B2 (en) 1997-05-22
JP2005124574A (ja) 2005-05-19
DE69434269T2 (de) 2006-03-30
AU7138294A (en) 1994-12-20
WO1994028132A2 (en) 1994-12-08

Similar Documents

Publication Publication Date Title
US6235496B1 (en) Nucleic acid encoding mammalian mu opioid receptor
US6103492A (en) Polynucleotide encoding mu opioid receptor
EP0700438B1 (en) Opioid receptors: compositions and methods
WO2002022801A9 (en) Mammalian receptor genes and uses
JP4208960B2 (ja) オピオイドレセプター遺伝子
US5591602A (en) Nucleic acid encoding opioid receptor
WO1995012670A9 (en) Opioid receptor: compositions and methods
WO2000031262A2 (en) Human neurotensin subtype 2 receptor
US7235366B1 (en) Methods of identifying agonists and antagonists of opioid receptors
US6432652B1 (en) Methods of screening modulators of opioid receptor activity
US6660496B1 (en) Nucleic acid molecules encoding a KOR3 kappa opioid receptor and the methods of producing the encoded receptor
US20080219925A1 (en) Delta opioid receptor protein
US7097988B1 (en) Methods for screening for substances that bind opioid receptors
EP0668912B1 (en) THE St-B17 SEROTONIN RECEPTOR
CA2147839C (en) The st-b17 serotonin receptor
US20030104572A1 (en) Nucleic acid molecules encoding kappa3, opioid receptors, receptors encoded thereby, and uses thereof

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued