JPH0940574A - Dietary composition - Google Patents

Dietary composition

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Publication number
JPH0940574A
JPH0940574A JP7212760A JP21276095A JPH0940574A JP H0940574 A JPH0940574 A JP H0940574A JP 7212760 A JP7212760 A JP 7212760A JP 21276095 A JP21276095 A JP 21276095A JP H0940574 A JPH0940574 A JP H0940574A
Authority
JP
Japan
Prior art keywords
extract
seaweed
gymnema
gardenia
diet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7212760A
Other languages
Japanese (ja)
Other versions
JP2959996B2 (en
Inventor
Shuichiro Ueda
修一郎 上田
Yoichi Kobayashi
洋一 小林
Hiroko Torimoto
裕子 鳥本
Minoru Hashimoto
実 橋本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Viox Inc
Original Assignee
Viox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viox Inc filed Critical Viox Inc
Priority to JP7212760A priority Critical patent/JP2959996B2/en
Publication of JPH0940574A publication Critical patent/JPH0940574A/en
Application granted granted Critical
Publication of JP2959996B2 publication Critical patent/JP2959996B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

PROBLEM TO BE SOLVED: To obtain a dietary composition, having excellent dietal effects and designed to suppress unfavorable effects such as soft or diarrheal feces, deterioration in immune strength, mental instability, inflammations, etc., of intestinal mucous membranes. SOLUTION: This dietary composition in the form of a tablet, a soft capsule, a beverage, etc., is obtained by adding and mixing a seaweed with a Gymnema extract and an extract of Gardenia jasminoides Ellis and, as necessary, other ingredients such as vitamins, calcium, an oligosaccharide, an excipient, etc. The ingredients are preferably blended in the following amounts expressed in terms of solids: 10-40 pts.wt. seaweed, 5-30 pts.wt. Gymnema extract and 5-20 pts.wt. extract of the Gardenia jasminoides Ellis. A sporophyll of Undaria pinnatifida Suringar is especially preferred as the seaweed.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は、海藻と、ギムネマエキ
スと、クチナシエキスとを有効成分とするダイエット組
成物に関する。
TECHNICAL FIELD The present invention relates to a diet composition containing seaweed, Gymnema extract and gardenia extract as active ingredients.

【0002】[0002]

【従来の技術】近年は、飽食の時代といわれ、肥満に悩
む人が増加し、健康上あるいは美容上の理由から、痩せ
るためにダイエット組成物を摂取する人が増えている。
2. Description of the Related Art In recent years, the number of people suffering from obesity is increasing, which is said to be a time of satiety, and for health or beauty reasons, more people are taking a diet composition to lose weight.

【0003】このようなダイエット組成物の一つとし
て、ギムネマエキスとクチナシエキスとを有効成分とし
て含有するもの、例えば錠剤などが知られている。これ
らの成分は、栄養素が生体内に吸収されるのを阻害する
作用を有するため、優れたダイエット効果(肥満抑制効
果)を表す。
As one of such diet compositions, those containing Gymnema extract and Gardenia extract as active ingredients, such as tablets, are known. Since these components have an action of inhibiting absorption of nutrients in the living body, they exhibit an excellent diet effect (obesity suppressing effect).

【0004】[0004]

【発明が解決しようとする課題】しかしながら、ギムネ
マエキスとクチナシエキスとの組合せからなるダイエッ
ト組成物は、栄養素の生体内への吸収阻害効果により、
腸内細菌による分解が進行して、物質の低分子化による
浸透圧の上昇が生じ、腸管細胞の体液が浸出して下痢な
どの症状を誘発させるという問題があった。
However, a diet composition comprising a combination of Gymnema extract and Gardenia extract, due to the effect of inhibiting absorption of nutrients in the body,
There is a problem that decomposition by intestinal bacteria progresses, the osmotic pressure is increased due to the low molecular weight of the substance, and the body fluid of the intestinal cells is leached to induce symptoms such as diarrhea.

【0005】したがって、多量に摂取した場合、軟便に
なったり、下痢症状になったりするため、免疫力が低下
したり、精神的に不安定になってイライラしたり、腸粘
膜に炎症が生じたりするという問題があった。
[0005] Therefore, if a large amount is ingested, it may cause loose stools or diarrhea, resulting in weakened immunity, mental instability and frustration, and inflammation of the intestinal mucosa. There was a problem of doing.

【0006】本発明はこれらの問題点を解決するために
なされたもので、その目的は、ギムネマエキスとクチナ
シエキスとの有するダイエット効果を損なうことなく、
下痢症状が起こらないようにして、免疫力の低下を防止
し、精神安定効果をもたらしてイライラを防止し、腸粘
膜に炎症が生じるのを防止することができるダイエット
組成物を提供することにある。
The present invention has been made to solve these problems, and its purpose is to maintain the diet effect of Gymnema extract and Gardenia extract without impairing the diet effect.
It is intended to provide a diet composition capable of preventing diarrhea symptoms, preventing a decrease in immunity, providing a tranquilizing effect, preventing frustration, and preventing inflammation of the intestinal mucosa. .

【0007】[0007]

【課題を解決するための手段】上記目的を達成するため
鋭意研究した結果、ギムネマエキス、クチナシエキス
に、海藻を配合することにより、ギムネマエキスとクチ
ナシエキスとのダイエット効果を損なうことなく、これ
らの有する問題点を解決できることを見出し、本発明を
完成するに至った。
[Means for Solving the Problems] As a result of intensive studies to achieve the above object, Gymnema extract and Gardenia extract were mixed with seaweed to prevent the diet effect of Gymnema extract and Gardenia extract from being lost. They have found that the problems they have can be solved, and have completed the present invention.

【0008】すなわち、本発明のダイエット組成物は、
海藻と、ギムネマエキスと、クチナシエキスとを有効成
分として含有することを特徴とする。
That is, the diet composition of the present invention is
It is characterized by containing seaweed, Gymnema extract, and gardenia extract as active ingredients.

【0009】以下、本発明を好ましい態様を挙げて詳細
に説明する。本発明において海藻とは、フコイダン、カ
ラギーナン、アルギン酸、寒天等の海藻多糖類を含有す
るものであれば特に限定されないが、抗体生成能を活性
化させる作用を有するフコイダンを多く含有するコン
ブ、ワカメ、ヒジキなどの褐藻類が好ましく、その中で
も、カルシウム、アルギン酸含量が多く、ヨードの過剰
摂取の心配の少ないワカメの芽株を用いるのが特に好ま
しい。また、海藻は、保存性の点から乾燥粉末化したも
のを用いることが好ましい。
The present invention will be described in detail below with reference to preferred embodiments. In the present invention, the seaweed, fucoidan, carrageenan, alginic acid, is not particularly limited as long as it contains a seaweed polysaccharide such as agar, kelp containing a large amount of fucoidan having an action of activating antibody-producing ability, wakame seaweed, Brown algae such as hijiki are preferable, and among them, it is particularly preferable to use a wakame bud strain which has a high calcium and alginic acid content and is less likely to be excessively ingested with iodine. In addition, it is preferable to use the dried and powdered seaweed from the viewpoint of storability.

【0010】本発明においてギムネマエキスとは、イン
ド原産のギムネマシルベスタ(ガガイモ科)という植物
の葉から、例えば水−エタノール系、アセトン系等の溶
媒を用いて抽出したエキスであって、トリテルペン系成
分であるギムネマ酸を主成分として含有するものであ
る。ギムネマエキスは、乾燥粉末化した製品が市販され
ており、容易に入手することができる。
In the present invention, Gymnema extract is an extract extracted from the leaves of a plant called Gymnema sylvestre (Coleoptera family), which is native to India, using a solvent such as water-ethanol system or acetone system, which is a triterpene-based component. Which contains Gymnemaic acid as a main component. Gymnema extract is commercially available as a dry powder product, and can be easily obtained.

【0011】本発明においてクチナシエキスとは、アカ
ネ科の常緑低木クチナシの成熟した果実から、例えば水
−エタノール系、アセトン系等の溶媒を用いて抽出した
エキスであって、ゲニポサイド、ガーデノサイドなどの
イリノイド配糖体を含有するものである。クチナシエキ
スも、乾燥粉末化した製品が市販されており、容易に入
手することができる。
In the present invention, the gardenia extract is an extract extracted from mature fruits of gardenia japonica, which belongs to the family Rubiaceae, using a solvent such as water-ethanol system or acetone system, and is an irioid such as geniposide or gardenoside. It contains a glycoside. As the gardenia extract, a dry powdered product is commercially available and can be easily obtained.

【0012】本発明のダイエット組成物は、海藻と、ギ
ムネマエキスと、クチナシエキスとを有効成分として含
有するが、その配合割合は、固形分換算で、海藻を10〜
40重量部、ギムネマエキスを5〜30重量部、クチナシエ
キスを5〜20重量部とするのが好ましい。このような配
合割合にすることにより、ギムネマエキスとクチナシエ
キスとのダイエット効果を十分に発揮しながら、これら
の成分が引き起こす下痢症状等の問題点を十分に防止す
ることができる。
The diet composition of the present invention contains seaweed, Gymnema extract, and gardenia extract as active ingredients, and the mixing ratio thereof is 10 to 10 seaweed in terms of solid content.
Preferably, 40 parts by weight, Gymnema extract is 5 to 30 parts by weight, and gardenia extract is 5 to 20 parts by weight. With such a blending ratio, the diet effect of Gymnema extract and gardenia extract can be sufficiently exerted, while the problems such as diarrhea symptoms caused by these components can be sufficiently prevented.

【0013】また、本発明のダイエット組成物の摂取量
は、例えば、海藻と、ギムネマエキスと、クチナシエキ
スとの配合比を7:3:2とした場合、有効成分量(海
藻と、ギムネマエキスと、クチナシエキスの合計量)と
して1〜10g/日とするのが好ましく、1.5 〜6g/日
とするのがより好ましい。摂取量が、上記有効成分量と
して1g/日未満の場合、ダイエット効果が期待でき
ず、10g/日を超えると、軟便や下痢になりやすくなる
ので好ましくない。
The diet composition of the present invention can be ingested in the amount of active ingredients (seaweed and Gymnema extract), for example, when the mixing ratio of seaweed, Gymnema extract and gardenia extract is 7: 3: 2. And the total amount of gardenia extract) is preferably 1 to 10 g / day, more preferably 1.5 to 6 g / day. If the amount of the active ingredient is less than 1 g / day, the diet effect cannot be expected, and if it exceeds 10 g / day, loose stool and diarrhea are likely to occur, which is not preferable.

【0014】本発明のダイエット組成物は、有効成分で
ある海藻と、ギムネマエキスと、クチナシエキスとの他
に、必要に応じてカルシウム、ビタミン類、オリゴ糖、
賦形剤等を配合することができる。
The diet composition of the present invention comprises, in addition to seaweed, Gymnema extract and gardenia extract, which are active ingredients, calcium, vitamins, oligosaccharides, if necessary.
Excipients and the like can be added.

【0015】また、本発明のダイエット組成物は、海藻
と、ギムネマエキスと、クチナシエキスとを有効成分と
して含有していれば、その製品形態は、錠剤、飲料、ソ
フトカプセル、粉剤等、いずれの形態であってもよく、
その形態に応じて他の成分を添加することができる。例
えば、錠剤とする場合には、粉末状にした海藻と、ギム
ネマエキスと、クチナシエキスとに、乳糖、ショ糖脂肪
酸エステル等の賦形剤を添加し、打錠することにより製
造することができる。また、ソフトカプセルとする場
合、上記成分をナタネ油等に混練し、ゼラチン等からな
るカプセルに入れて製造することができる。
If the diet composition of the present invention contains seaweed, Gymnema extract and gardenia extract as active ingredients, the product form can be any form such as tablets, beverages, soft capsules, powders and the like. May be
Other components can be added depending on the form. For example, in the case of tablets, it can be produced by adding excipients such as lactose and sucrose fatty acid ester to powdered seaweed, Gymnema extract, gardenia extract, and tableting. . In the case of soft capsules, the above components can be kneaded with rapeseed oil or the like and placed in a capsule made of gelatin or the like to be manufactured.

【0016】なお、海藻は、食用とされているものであ
り、ギムネマエキス及びクチナシエキスは、従来よりダ
イエット組成物等に用いられているものであるので、人
体に対しては安全である。
Seaweed is edible, and Gymnema extract and gardenia extract are conventionally used in diet compositions and the like, so they are safe for the human body.

【0017】[0017]

【作用】ギムネマエキスに含まれるギムネマ酸は、糖分
の腸管吸収抑制効果を有し、肥満抑制効果、特に成人病
の発生率が高い内臓脂肪蓄積型肥満の抑制効果があるこ
とが知られて(「期待されるギムネマ酸の生理機能」、
日地康武、食品と開発、Vol.28、No.2、19
93年2月号、第10〜13頁参照)。
[Action] Gymnema acid contained in Gymnema extract has an inhibitory effect on intestinal absorption of sugar and is known to have an obesity suppressing effect, particularly an effect of suppressing visceral fat accumulating obesity with a high incidence of adult diseases ( "Expected Physiological Function of Gymnemic Acid",
Yujitake Hiji, Food and Development, Vol. 28, no. 2, 19
See the February 1993 issue, pages 10-13).

【0018】また、クチナシエキスに含まれるイリノイ
ド配糖体は、脂肪を含む食物の胃腸管通過時間を短くし
て脂肪の吸収を阻害することによって、肥満抑制効果を
発揮することが知られている(特開昭61−1618号
参照)。
Further, it is known that the iridin glycoside contained in gardenia extract exerts an obesity suppressing effect by shortening the gastrointestinal tract transit time of fat-containing foods and inhibiting fat absorption. (See JP-A-61-1618).

【0019】したがって、ギムネマエキスとクチナシエ
キスとを組み合わせて摂取すると、糖分や脂肪が生体内
に吸収されるのが阻害され、それによって優れたダイエ
ット効果がもたらされる。
Therefore, when ingested in combination with Gymnema extract and gardenia extract, absorption of sugar and fat in the living body is inhibited, whereby an excellent diet effect is brought about.

【0020】しかし、これらの成分は、摂取しすぎる
と、軟便、下痢便を引き起こすため、免疫力が低下した
り、精神的に不安定になってイライラしたり、腸粘膜に
炎症が生じたりする。
However, if these components are ingested too much, they cause loose stools and diarrhea stools, resulting in weakened immunity, mental instability and frustration, and inflammation of the intestinal mucosa. .

【0021】ところが、これらの成分に、更に海藻を配
合すると、上記問題点が解決されることがわかった。こ
の理由は次のように考えられる。
However, it has been found that the above problems can be solved by further adding seaweed to these components. The reason is considered as follows.

【0022】すなわち、コンブ、ワカメ、ヒジキなどの
海藻は、フコイダン、アルギン酸等の海藻多糖類や、カ
ルシウム、カリウム等のミネラルを多く含有している。
That is, seaweeds such as kelp, seaweed, and hijiki contain a lot of seaweed polysaccharides such as fucoidan and alginic acid, and minerals such as calcium and potassium.

【0023】このうち、フコイダンは、抗体生成能を活
性化させる作用を有しているので、ダイエットにより、
免疫力が低下するのを防止する。また、血液浄化作用を
有しているので、その効果も期待できる(「藻類の酸性
多糖類とその生理活性」、西澤一俊、食品開発、Vo
l.18、No.11、第28〜35頁参照)。
Of these, fucoidan has the effect of activating the antibody-producing ability, and therefore,
Prevents a decrease in immunity. In addition, since it has a blood purifying action, its effect can be expected ("Algae acidic polysaccharide and its physiological activity", Kazutoshi Nishizawa, Food Development, Vo.
l. 18, No. 11, pp. 28-35).

【0024】また、アルギン酸は、保水力が強いことか
ら、下痢便を保型し、下痢症状を改善する。また、腸壁
の粘膜保護効果を有していることから腸粘膜に炎症がお
こるのを防止する。
Further, alginic acid has a strong water-retaining power, and therefore, maintains the shape of diarrhea stool and improves diarrhea symptoms. In addition, since it has a mucosal protective effect on the intestinal wall, it prevents inflammation of the intestinal mucosa.

【0025】更に、カルシウムは、イライラを鎮め、精
神安定効果をもたらす作用を有することが知られてい
る。
Further, it is known that calcium has a function of calming irritability and producing a tranquilizing effect.

【0026】したがって、海藻を添加することによっ
て、ギムネマエキス及びクチナシエキスによってもたら
される軟便、下痢便、免疫力の低下、精神的な不安定、
腸粘膜の炎症等の弊害を抑制し、ダイエット組成物の長
期に亙る摂取を可能にすることができる。
Therefore, by adding seaweed, loose stools, diarrhea stools, decreased immunity, mental instability brought about by Gymnema extract and Gardenia extract,
It is possible to suppress adverse effects such as inflammation of the intestinal mucosa and enable long-term intake of the diet composition.

【0027】[0027]

【実施例】【Example】

実施例1、比較例1、2、対照1、2 ギムネマエキスと、クチナシエキスと、ワカメの芽株
と、澱粉とを、1日の摂取量が表1に示す量となるよう
に配合して、粉剤を調製した。これらの粉剤をそれぞ
れ、実施例1、比較例1、2、対照1、2とする。
Example 1, Comparative Examples 1 and 2, Controls 1 and 2, Gymnema extract, gardenia extract, seaweed bud strain, and starch were blended so that the daily intake was the amount shown in Table 1. , A powder was prepared. These powders are referred to as Example 1, Comparative Examples 1 and 2, and Controls 1 and 2, respectively.

【0028】これらの粉剤を、それぞれ15名のパネラ
ーに、4週間、食後に服用させて、便の状態、疲労感を
報告させ、服用4週間後の体重の減少率の平均を求め
た。なお、体重は、午前9〜11時に、排便後測定し
た。また、下痢が生じた場合には、摂取を中止した。更
に、疲労感は、なしを−、ややありを±、ありを+とし
て表した。この結果を表1に示す。
These powders were taken by each of 15 panelists after eating for 4 weeks, the stool condition and feeling of tiredness were reported, and the average weight loss rate after 4 weeks was calculated. The body weight was measured after defecation at 9 to 11 am. If diarrhea occurred, the intake was discontinued. Furthermore, the feeling of fatigue was expressed as −, slightly with ±, and with +. Table 1 shows the results.

【0029】[0029]

【表1】 [Table 1]

【0030】表1の結果から、ギムネマエキス及びクチ
ナシエキスを摂取した場合、いずれも体重の減少がみら
れ、その摂取量が多いほど、体重の減少率も大きくなる
と共に、便の状態が悪くなり、疲労感が大きくなるが、
これらにワカメの芽株を配合した実施例の場合、体重の
減少率が大きいにもかかわらず、下痢の人が少なく、疲
労感も起こらないことがわかる。
From the results shown in Table 1, when Gymnema extract and Gardenia extract were ingested, weight loss was observed in both cases. The higher the intake, the greater the weight loss rate and the poorer stool condition. , I feel more tired,
It can be seen that, in the case of the examples in which the wakame bud strain was added to these, the number of diarrhea was small and the tiredness did not occur even though the weight loss rate was large.

【0031】実施例2 8錠中に、ギムネマエキスの粉末品800mg 、クチナシエ
キスの粉末品500mg 、ワカメの芽株の乾燥粉末1000mg、
カルシウム剤200mg 、オリゴ糖200mg 、及びビタミン類
を日本人の1日に必要とされる量となるように加えたも
のに、乳糖及びショ糖脂肪酸エステルを少量添加し、常
法によって打錠し、錠剤を製造した。
Example 2 In 8 tablets, 800 mg of Gymnema extract powder, 500 mg of Gardenia extract powder, 1000 mg of dried powder of wakame sprout,
Calcium agent 200mg, oligosaccharide 200mg, and vitamins were added to the amount required for Japanese in a day, a small amount of lactose and sucrose fatty acid ester were added, and the mixture was tableted by a conventional method. Tablets were produced.

【0032】この錠剤を13名のパネラーに毎食後8錠
ずつ4週間服用させたところ、体重の減少率が3%を超
えたものが8名あった。また、疲労感や下痢等の症状が
発生したものは、2名しかいなかった。
When the tablets were taken by 13 panelists, 8 tablets after each meal, for 4 weeks, 8 of them had a weight loss rate of more than 3%. Also, only two people had symptoms such as fatigue and diarrhea.

【0033】[0033]

【発明の効果】以上説明したように、本発明によれば、
ギムネマエキス、クチナシエキスと共に、海藻を含有さ
せたので、ギムネマエキス及びクチナシエキスのダイエ
ット効果を損なうことなく、これらの成分の摂取により
起こる軟便、下痢等を防止し、それに伴う免疫力の低
下、精神的不安定によるイライラ、腸粘膜の炎症等を防
止することができる。したがって、下痢等の副作用が生
じることなく、効果的に、安全にダイエットすることが
できる。
As described above, according to the present invention,
Gymnema extract, gardenia extract, together with seaweed, without compromising the diet effect of Gymnema extract and gardenia extract, prevent loose stools, diarrhea, etc. caused by ingestion of these ingredients, resulting in a decrease in immunity, mental. It is possible to prevent irritation due to mental instability and inflammation of the intestinal mucosa. Therefore, it is possible to diet effectively and safely without causing side effects such as diarrhea.

Claims (3)

【特許請求の範囲】[Claims] 【請求項1】 海藻と、ギムネマエキスと、クチナシエ
キスとを有効成分として含有することを特徴とするダイ
エット組成物。
1. A diet composition comprising seaweed, Gymnema extract, and gardenia extract as active ingredients.
【請求項2】 固形分換算で、前記海藻を10〜40重量
部、前記ギムネマエキスを5〜30重量部、前記クチナシ
エキスを5〜20重量部の配合割合で含有する請求項1記
載のダイエット組成物。
2. The diet according to claim 1, containing 10 to 40 parts by weight of the seaweed, 5 to 30 parts by weight of the Gymnema extract, and 5 to 20 parts by weight of the gardenia extract in terms of solid content. Composition.
【請求項3】 前記海藻がワカメの芽株である請求項1
又は2記載のダイエット組成物。
3. The seaweed is a sprout of Wakame seaweed.
Or the diet composition according to 2.
JP7212760A 1995-07-28 1995-07-28 Diet composition Expired - Fee Related JP2959996B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7212760A JP2959996B2 (en) 1995-07-28 1995-07-28 Diet composition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7212760A JP2959996B2 (en) 1995-07-28 1995-07-28 Diet composition

Publications (2)

Publication Number Publication Date
JPH0940574A true JPH0940574A (en) 1997-02-10
JP2959996B2 JP2959996B2 (en) 1999-10-06

Family

ID=16627956

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7212760A Expired - Fee Related JP2959996B2 (en) 1995-07-28 1995-07-28 Diet composition

Country Status (1)

Country Link
JP (1) JP2959996B2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047208A1 (en) * 1996-06-12 1997-12-18 Takara Shuzo Co., Ltd. Foods or drinks
US6573250B2 (en) 1996-06-12 2003-06-03 Takara Shuzo Co., Ltd. Food or beverage additive containing fucoidan and food and beverage containing fucoidan
KR100692402B1 (en) * 2005-07-26 2007-03-09 건국대학교 산학협력단 A pharmaceutical composition comprising the extract of gardenia for treating or preventing depression disease

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047208A1 (en) * 1996-06-12 1997-12-18 Takara Shuzo Co., Ltd. Foods or drinks
US6573250B2 (en) 1996-06-12 2003-06-03 Takara Shuzo Co., Ltd. Food or beverage additive containing fucoidan and food and beverage containing fucoidan
JP3505185B2 (en) * 1996-06-12 2004-03-08 タカラバイオ株式会社 Food or beverage
US7422750B2 (en) 1996-06-12 2008-09-09 Takara Bio Inc. Food or beverage containing fucoidan and method of production thereof
KR100692402B1 (en) * 2005-07-26 2007-03-09 건국대학교 산학협력단 A pharmaceutical composition comprising the extract of gardenia for treating or preventing depression disease

Also Published As

Publication number Publication date
JP2959996B2 (en) 1999-10-06

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