JPH08509867A - イースト菌株およびイースト中での異種構造たんぱく質の発現方法 - Google Patents
イースト菌株およびイースト中での異種構造たんぱく質の発現方法Info
- Publication number
- JPH08509867A JPH08509867A JP6525318A JP52531894A JPH08509867A JP H08509867 A JPH08509867 A JP H08509867A JP 6525318 A JP6525318 A JP 6525318A JP 52531894 A JP52531894 A JP 52531894A JP H08509867 A JPH08509867 A JP H08509867A
- Authority
- JP
- Japan
- Prior art keywords
- strain
- protein
- cerevisiae
- higf
- yeast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
- C12N1/185—Saccharomyces isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
- C12R2001/865—Saccharomyces cerevisiae
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939301583A SE9301583D0 (sv) | 1993-05-07 | 1993-05-07 | Yeast strain and methods for expressing heterologous proteins in yeast |
SE9301583-2 | 1993-05-07 | ||
PCT/SE1994/000421 WO1994026873A1 (en) | 1993-05-07 | 1994-05-06 | Yeast strain and methods for expressing heterologous proteins in yeast |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH08509867A true JPH08509867A (ja) | 1996-10-22 |
Family
ID=20389870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6525318A Pending JPH08509867A (ja) | 1993-05-07 | 1994-05-06 | イースト菌株およびイースト中での異種構造たんぱく質の発現方法 |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0698086A1 (sv) |
JP (1) | JPH08509867A (sv) |
AU (1) | AU683061B2 (sv) |
CA (1) | CA2161973A1 (sv) |
NZ (1) | NZ266045A (sv) |
SE (1) | SE9301583D0 (sv) |
WO (1) | WO1994026873A1 (sv) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002542761A (ja) * | 1999-01-30 | 2002-12-17 | デルタ バイオテクノロジー リミテッド | 方 法 |
US8232377B2 (en) | 2006-05-16 | 2012-07-31 | National Institute Of Advanced Industrial Science And Technology | Method for high-level secretory production of protein |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
CA2431013A1 (en) * | 2000-12-05 | 2002-06-13 | The Penn State Research Foundation | Methods and compositions for highly efficient production of heterologous proteins in yeast |
DE602005016946D1 (de) * | 2004-09-02 | 2009-11-12 | Lilly Co Eli | Muteine des fibroblasten-wachstumsfaktors 21 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0276846A3 (en) * | 1987-01-29 | 1989-07-26 | Zymogenetics, Inc. | Colony-stimulating factor derivatives |
AU625392B2 (en) * | 1987-10-29 | 1992-07-09 | Zymogenetics Inc. | Methods of regulating protein glycosylation |
-
1993
- 1993-05-07 SE SE19939301583A patent/SE9301583D0/sv unknown
-
1994
- 1994-05-06 EP EP94915327A patent/EP0698086A1/en not_active Withdrawn
- 1994-05-06 NZ NZ266045A patent/NZ266045A/en unknown
- 1994-05-06 CA CA002161973A patent/CA2161973A1/en not_active Abandoned
- 1994-05-06 JP JP6525318A patent/JPH08509867A/ja active Pending
- 1994-05-06 AU AU66626/94A patent/AU683061B2/en not_active Ceased
- 1994-05-06 WO PCT/SE1994/000421 patent/WO1994026873A1/en not_active Application Discontinuation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002542761A (ja) * | 1999-01-30 | 2002-12-17 | デルタ バイオテクノロジー リミテッド | 方 法 |
US8232377B2 (en) | 2006-05-16 | 2012-07-31 | National Institute Of Advanced Industrial Science And Technology | Method for high-level secretory production of protein |
JP5131666B2 (ja) * | 2006-05-16 | 2013-01-30 | 独立行政法人産業技術総合研究所 | タンパク質の高分泌生産方法 |
Also Published As
Publication number | Publication date |
---|---|
SE9301583D0 (sv) | 1993-05-07 |
CA2161973A1 (en) | 1994-11-24 |
WO1994026873A1 (en) | 1994-11-24 |
AU683061B2 (en) | 1997-10-30 |
NZ266045A (en) | 1997-06-24 |
EP0698086A1 (en) | 1996-02-28 |
AU6662694A (en) | 1994-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE4244915C2 (de) | DNA-Moleküle codierend Proteine, die an der O-Glykosylierung von Proteinen beteiligt sind | |
Paravicini et al. | Alternative pathways for the sorting of soluble vacuolar proteins in yeast: a vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases. | |
Miller et al. | Role of NAD-linked glutamate dehydrogenase in nitrogen metabolism in Saccharomyces cerevisiae | |
KR910001809B1 (ko) | Csf 단백질 생산방법 및 정제방법 | |
JP2704115B2 (ja) | 形質転換細胞を選択する方法 | |
DE60032370T2 (de) | Hefevarianten und verfahren zur herstellung von glykoprotein enthaltenden zuckerketten vom säugetiertyp | |
JPH08504561A (ja) | 組換えヒトラクトフェリンの製造 | |
Wartmann et al. | Temperature-dependent dimorphism of the yeast Arxula adeninivorans Ls3 | |
JPH04502861A (ja) | 植物および植物細胞中での非相同タンパク類の生産 | |
CA2050468C (en) | A thermostable (1,3-1,4)-.beta.-glucanase | |
Chiu et al. | HTS1 encodes both the cytoplasmic and mitochondrial histidyl-tRNA synthetase of Saccharomyces cerevisiae: mutations alter the specificity of compartmentation. | |
AU625392B2 (en) | Methods of regulating protein glycosylation | |
EP0654081B1 (de) | Hypoglycosylierte recombinante glucoseoxidase | |
KR100490190B1 (ko) | 개량된 단백질 발현균주 | |
JPH08509867A (ja) | イースト菌株およびイースト中での異種構造たんぱく質の発現方法 | |
EP0780468A1 (en) | Transformant producing substance pf1022 and method for transforming microorganism belonging to the class hyphomycetes | |
US5705616A (en) | Proteins from yeast host strains with defects in N-glycosylation | |
Maundrell et al. | Cloning and characterization of two genes restoring acid phosphatase activity in pho1− mutants of Schizosaccharomyces pombe | |
EP2918680A1 (en) | Method for producing, isolating and purifying recombinant human antitryptase (osraat) from rice seeds | |
CN112074608A (zh) | 用于产生具有高聚糖占有率的糖分子的重组生物体和方法 | |
JP2770010B2 (ja) | 酵母のマンノース−1−リン酸転移を正に制御する遺伝子ならびにこの遺伝子の欠損変異株を利用する高マンノース型中性糖鎖の製造方法 | |
KR101863892B1 (ko) | 재조합 mnn14 단백질을 이용한 만노스인산화 반응 | |
Finck et al. | Defective threonine-linked glycosylation of human insulin-like growth factor in mutants of the yeast Saccharomyces cerevisiae | |
WO2004003205A1 (en) | Hansenula polymorpha mutant strains with defect in outer chain biosynthesis and the production of recombinant glycoproteins using the same strains | |
JPH0673458B2 (ja) | 小麦胚芽凝集素蛋白質の微生物学的製造法 |