JPH08500967A - ヒトA1,A2aおよびA2bアデノシン受容体をエンコードするDNA配列 - Google Patents

ヒトA1,A2aおよびA2bアデノシン受容体をエンコードするDNA配列

Info

Publication number
JPH08500967A
JPH08500967A JP6500961A JP50096194A JPH08500967A JP H08500967 A JPH08500967 A JP H08500967A JP 6500961 A JP6500961 A JP 6500961A JP 50096194 A JP50096194 A JP 50096194A JP H08500967 A JPH08500967 A JP H08500967A
Authority
JP
Japan
Prior art keywords
human
dna
adenosine
adenosine receptor
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6500961A
Other languages
English (en)
Japanese (ja)
Inventor
ダイアン ピアース,ケリー
アンドレア タウンゼンドーニコルソン,コンスタンス
シャイン,ジョン
ファーロング,ティモシィ
セルビー,リサ
Original Assignee
ガーヴァン インスティチュート オブ メディカル リサーチ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ガーヴァン インスティチュート オブ メディカル リサーチ filed Critical ガーヴァン インスティチュート オブ メディカル リサーチ
Publication of JPH08500967A publication Critical patent/JPH08500967A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP6500961A 1992-06-12 1993-06-11 ヒトA1,A2aおよびA2bアデノシン受容体をエンコードするDNA配列 Pending JPH08500967A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2936 1980-03-27
AUPL293692 1992-06-12
PCT/AU1993/000277 WO1993025677A1 (fr) 1992-06-12 1993-06-11 SEQUENCES D'ADN CODANT LES RECEPTEURS HUMAINS DE L'ADENOSINE A1, A2a ET A2b

Publications (1)

Publication Number Publication Date
JPH08500967A true JPH08500967A (ja) 1996-02-06

Family

ID=3776217

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6500961A Pending JPH08500967A (ja) 1992-06-12 1993-06-11 ヒトA1,A2aおよびA2bアデノシン受容体をエンコードするDNA配列

Country Status (3)

Country Link
EP (1) EP0644935A1 (fr)
JP (1) JPH08500967A (fr)
WO (1) WO1993025677A1 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2264948B (en) * 1992-03-13 1996-10-16 Merck & Co Inc Human adenosine receptors
US5646156A (en) * 1994-04-25 1997-07-08 Merck & Co., Inc. Inhibition of eosinophil activation through A3 adenosine receptor antagonism
GB2289218A (en) * 1994-05-06 1995-11-15 Merck & Co Inc Inhibition of TNFalpha production with agonists of the A2b subtype of the adenosine receptor
US6040296A (en) * 1995-06-07 2000-03-21 East Carolina University Specific antisense oligonucleotide composition & method for treatment of disorders associated with bronchoconstriction and lung inflammation
US7034007B1 (en) 1995-06-07 2006-04-25 East Carolina University Low adenosine anti-sense oligonucleotide, compositions, kit & method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) & surfactant depletion
US6025339A (en) * 1995-06-07 2000-02-15 East Carolina University Composition, kit and method for treatment of disorders associated with bronchoconstriction and lung inflammation
US20020015967A1 (en) * 1998-06-02 2002-02-07 Lauren Silverman Functional expression of adenosine receptors in yeast
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
US6221660B1 (en) * 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US6214807B1 (en) 1999-06-22 2001-04-10 Cv Therapeutics, Inc. C-pyrazole 2A A receptor agonists
USRE47351E1 (en) 1999-06-22 2019-04-16 Gilead Sciences, Inc. 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists
US6403567B1 (en) 1999-06-22 2002-06-11 Cv Therapeutics, Inc. N-pyrazole A2A adenosine receptor agonists
CA2388865A1 (fr) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Recepteurs couples a une proteine g
WO2001036632A2 (fr) * 1999-11-17 2001-05-25 Compugen Ltd. Variants d'epissage alternatif
US20020012946A1 (en) 2000-02-23 2002-01-31 Luiz Belardinelli Method of identifying partial agonists of the A2A receptor
US8470801B2 (en) 2002-07-29 2013-06-25 Gilead Sciences, Inc. Myocardial perfusion imaging methods and compositions
US20050020915A1 (en) 2002-07-29 2005-01-27 Cv Therapeutics, Inc. Myocardial perfusion imaging methods and compositions
US7683037B2 (en) 2002-07-29 2010-03-23 Gilead Palo Alto, Inc. Myocardial perfusion imaging method
JP2008517063A (ja) 2004-10-20 2008-05-22 シーブイ・セラピューティクス・インコーポレイテッド A2aアデノシンレセプターアゴニストの使用
PL1989214T3 (pl) 2006-02-03 2017-07-31 Gilead Sciences, Inc. Proces otrzymywania agonisty receptora adenozynowego a2a i jego polimorfów
GB2456235B8 (en) * 2007-03-22 2009-12-09 Heptares Therapeutics Ltd Stable beta-adrenergic receptor mutants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA902280B (en) * 1989-03-29 1990-12-28 Merrell Dow Pharma Selective adenosine receptor agents
WO1991016056A1 (fr) * 1990-04-16 1991-10-31 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Emploi d'agonistes de recepteur purinergique utilises comme agents antineoplastiques
WO1992021701A1 (fr) * 1991-06-05 1992-12-10 The United States Of America Represented By The Secretary, Department Of Health And Human Services Lignees cellulaires transfectees de mammifere, exprimant le recepteur d'adenosine a¿1?

Also Published As

Publication number Publication date
WO1993025677A1 (fr) 1993-12-23
EP0644935A1 (fr) 1995-03-29

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