JPH08175914A - Solubilized formulation for injection into tree trunk and method for preventing pines from dying with the same formulation - Google Patents

Abstract

PURPOSE: To obtain a solubilized formulation for injection into a tree trunk, improved in migration properties of a medicine into the tree body and useful for preventing pines from dying by solubilizing a hardly water-soluble insecticide and/or germicide in water or a solvent miscible with the water and a specific nonionic surfactant. CONSTITUTION: This solubilized formulation for injection into a tree trunk is obtained by adding a solubilizing agent containing a nonionic surfactant having >=12 HLB and water and/or a solvent miscible with the water to an insecticide and/or a germicide having <=5g/l solubility in water and imparting the solubility thereto. Thereby, the migration properties of the medicine into the tree body is improved. Pines are prevented from dying by using the formulation. Organophosphorus-based insecticides, benzimidazole-based vermifuges, etc., are cited as the insecticide and polyhaloalkylthio- based, benzimidazole-based germicides, etc., are cited as the germicide. A polyoxyethylene castor oil, a polyoxyethylene hardened castor oil, etc., are cited as the nonionic surfactant. Lower alcohols, polyhydric alcohols, glycol esters, etc., are cited as the solvent miscible with the water.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a solubilized preparation for injecting tree trunks and a method for preventing pine tree mortality by the preparation. More specifically, a sparingly water-soluble insecticide and / or fungicide is added to water and / or
Or a solubilized preparation for injecting into a trunk, which is improved in migration into the tree of the drug by solubilizing it with a solvent miscible with water and a specific nonionic surfactant, and a method for preventing pine damage by the preparation. Is.

[0002]

2. Description of the Related Art Tree trunk injection agents have been conventionally used to effectively prevent the death of trees (particularly pine trees) by pests in the trees. The drug injected into the tree trunk dissolves in water in the tree that is absorbed from the roots and travels through the temporary conduit to the leaves to transfer to the branches.Therefore, the tree trunk injection needs to have some solubility in water. ing. Regarding this, Matsuura reported that only the drug having a solubility in water of more than 1000 ppm was effective against pine wilt disease by stem injection (Plant control, 38, p27-31,
1984).

It is also possible to observe that among commercially available tree trunk injection agents, since the solubility in water is low, a considerable amount of the agent causes crystal precipitation in the vicinity of the injection site, resulting in inhibition of water conduction. it can. It is considered that this is because the drug could not be dissolved in the stem flow and crystals were precipitated.

Since the drug injected into the tree trunk is not dissolved in this way, the drug is not smoothly transferred into the tree, and as a result, the effect on the pests in the tree is not stably sustained. ing.

[0005]

SUMMARY OF THE INVENTION The present invention was devised to solve the above-mentioned problems of the prior art, and its purpose is to make a poorly water-soluble insecticide and fungicide soluble. Accordingly, it is an object of the present invention to provide a solubilized preparation for injecting into a trunk, which improves migration of a drug in a tree and effectively prevents tree death, and a method for preventing pine tree death using the preparation.

[0006]

[Means for Solving the Problems] The present inventors have completed the present invention as a result of extensive studies on a solubilized preparation for injecting into a trunk, which is excellent in stability and sustainability of the effect in order to achieve the above object.

That is, according to the present invention, (i) the solubility in water is 5
g / l or less insecticide and / or fungicide, (ii) HLB is 1
A solubilizer containing two or more nonionic surfactants, (ii
i) A solubilized preparation for tree trunk injection, which comprises water and / or a solvent miscible with water.

The insecticides used in the present invention include, for example, organophosphorus insecticides such as fenitrothion, prothiophos, propaphos, fosthiazate and pyraclofos,
Benzimidazole anthelmintic, carbamate insecticide,
Examples include synthetic pyrethroid insecticides, insect growth regulators, acaricides and macrolide antibiotics. These can be used alone or in combination of two or more.

As the bactericide used in the present invention,
Examples thereof include polyhaloalkylthio fungicides, benzimidazole fungicides, acylalanine fungicides, ergosterol biosynthesis inhibitors and antibiotics. These may be used alone or in combination of two or more.

The solubilizer used in the present invention is HLB.
It is essential that (hydrophile-lipophile balance) contains 12 or more nonionic surfactants. Examples of the solubilizer used in the present invention include alkyl sulfates, alkane sulfonates, alkyl benzene sulfonates, alkyl phosphates, N-acyl sarcosine salts, N-acyl alanine salts and the like as anionic surfactants. Succinates and the like are cationic amines such as alkylamines, alkyltrimethylammonium salts, dialkyldimethylammonium salts, alkyldimethylbenzylammonium salts and alkylpyridinium salts, and nonionic surfactants are polyoxyethylene castor oils. , Polyoxyethylene hydrogenated castor oils, polyoxyethylene alkyl ethers, polyoxyethylene alkyl phenyl ethers, polyoxyethylene alkyl phenyl ether formaldehyde condensates, poly Tylene glycol fatty acid ester, polyoxyethylene polyoxypropylene alkyl ethers, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester and propylene glycol Mono-fatty acid esters and the like, and further amphoteric surfactants include aminocarboxylic acids, carboxybetaines and sulfobetaines.

Examples of the water-miscible solvent used in the present invention include lower alcohols such as methanol and ethanol, ethylene glycol, propylene glycol, diethylene glycol, 1,3-butylene glycol, isoprene glycol and the like. Examples thereof include polyhydric alcohols, polar solvents such as acetone, acetonitrile and tetrahydrofuran, glycol ethers such as ethylene glycol monomethyl ether, glycol esters such as ethylene glycol monoacetate and dioxane.

The amount of each component of the solubilized preparation for injecting tree trunks of the present invention can be appropriately changed, but 1 to 50 pesticides and / or fungicides are used.
% By weight, preferably 5-20% by weight, 1-6 solubilizers
0% by weight, preferably 5 to 30% by weight, water and / or water-miscible solvent 10 to 80% by weight, preferably 30%
Up to 70% by weight, respectively.

The respective components of the solubilized preparation for injecting tree trunks of the present invention can be blended by any method. For example, a poorly water-soluble insecticide and / or bactericide is used as a solvent and / or water. The solubilized preparation for injecting tree trunks of the present invention can be easily produced by a method of adding a solubilizing agent after being dissolved in. When applied to trees, the application rate of the solubilized formulation for injecting tree trunks of the present invention can be appropriately changed depending on the purpose, time, age of the tree, damage situation and the like. To prevent the death of pine trees, a method is used in which a hole is bored in the trunk of the pine tree by boring, the solubilized preparation of the present invention is injected through the hole, and the pinewood nematode is exterminated by translocation into the tree. can do.

[0014]

EXAMPLES Next, the excellent effects of the solubilized preparation of the present invention will be described with reference to Examples, but the present invention is not limited thereto.

Example 1 With respect to solubilized preparations 1 to 6 and non-solubilized preparations 7 to 9 in which prothiophos, fenitrothion and pyraclofos were blended as shown in Table 1, a test for preventing death by a black pine having a breast height diameter of 10 to 15 cm was conducted by the following test method. It was carried out by. Injected solubilized formulation 1-6 and non-solubilized formulation 7-
The composition of No. 9 is shown in Table 1, and the result of the mortality prevention test is shown in Table 2.

Test method for prevention of mortality After injecting 100 ml of the preparation of Table 1 into pine trees, one month later, 0.3 ml of a highly toxic pine wood nematode (S6-1) suspension (100,000 heads / ml) was inoculated, After 3 months, the effect of preventing death was evaluated.

[0017]

[Table 1]

[0018]

[Table 2]

Results As is clear from the test results in Table 2, all the solubilized preparations of the present invention exhibited a stable mortality preventing effect as compared with the non-solubilized preparation of the comparative control.

Example 2 With respect to the solubilized preparations 10 to 15 and the non-solubilized preparations 16 and 17 in which thiabendazole and milbemectin were blended as shown in Table 3, a mortality prevention test by a black pine having a breast height diameter of 10 to 15 cm was conducted by the following test method. did.
Injected solubilized formulation 10-15 and non-solubilized formulation 1
The compositions of Nos. 6 and 17 are shown in Table 3, and the results of the damage prevention test are shown in Table 4.

Test Method for Preventing Mortality After injecting 50 ml of the preparation of Table 3 into a pine tree, one month later, 0.3 ml of a highly toxic pine wood nematode (S6-1) suspension (100,000 heads / ml) was inoculated, After 3 months, the effect of preventing death was evaluated.

[0022]

[Table 3]

[0023]

[Table 4]

Results As is clear from the test results in Table 4, each of the solubilized preparations of the present invention exhibited a stable effect of preventing mortality as compared with the non-solubilized preparation of the comparative control.

[0025]

INDUSTRIAL APPLICABILITY The present invention can be effectively used as a tree trunk injection agent by solubilizing a poorly water-soluble insecticide and / or fungicide, which has been difficult to use as a tree trunk injection agent. You can In addition, the solubilized preparation of the present invention prevents the occurrence of phytotoxicity by improving the solubility of the drug in water, facilitates the transfer of the drug into the tree, and improves the sustainability and stability of the effect on pests in the tree. Can be increased. Furthermore, the solubilized preparation of the present invention can provide a preparation more effective than before in preventing pine wilt damage due to pine wilt disease.

Continuation of the front page (51) Int.Cl. ⁶ Identification code Office reference number FI technical display area A01N 57/16 103 A

Claims (7)

[Claims] 1. (i) An insecticide and / or bactericide having a solubility in water of 5 g / l or less, (ii) a solubilizer containing a nonionic surfactant having an HLB of 12 or more, (iii) water and And / or a solubilized preparation for tree trunk injection, which contains a solvent miscible with water. 2. The tree trunk injection solubilized preparation according to claim 1, wherein the pesticide and / or bactericide has a solubility in water of 1 g / l or less. 3. The insecticide selected from the group consisting of organophosphorus insecticides, benzimidazole insecticides, carbamate insecticides, synthetic pyrethroid insecticides, insect growth regulators, acaricides and macrolide antibiotics. The solubilized preparation for trunk injection according to claim 1 or 2, which is at least one insecticide. 4. The bactericide is a polyhaloalkylthio bactericide, a benzimidazole bactericide, a dicarboximide bactericide, a carboxamide bactericide, an acylalanine bactericide, an ergosterol biosynthesis inhibitor and an antibiotic. The solubilized preparation for trunk injection according to claim 1, which is at least one fungicide selected from the group consisting of: 5. The nonionic surfactant is polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene alkylphenyl ether formaldehyde condensation. Products, polyethylene glycol fatty acid ester, polyoxyethylene polyoxypropylene alkyl ethers, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene sorbitol fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester And at least one nonionic surfactant selected from the group consisting of propylene glycol monofatty acid esters.
A solubilized preparation for tree trunk injection according to any one of 1. 6. The water-miscible solvent is at least one solvent selected from the group consisting of lower alcohols, polyhydric alcohols, glycol esters, acetone, acetonitrile, tetrahydrofuran and dioxane. 6. The solubilized preparation for trunk injection according to any one of to 5. 7. A pine tree nematode (Bursaphelenchus) by injecting an effective amount of the solubilized preparation for injecting tree trunks according to claims 1 to 6 into a tree trunk of pine and translocating it into the tree.
xylophilus), a method for preventing the death of pine trees.