JPH07505621A - 外科手術中における腫瘍組織の検出および探知法 - Google Patents

外科手術中における腫瘍組織の検出および探知法

Info

Publication number
JPH07505621A
JPH07505621A JP5516829A JP51682993A JPH07505621A JP H07505621 A JPH07505621 A JP H07505621A JP 5516829 A JP5516829 A JP 5516829A JP 51682993 A JP51682993 A JP 51682993A JP H07505621 A JPH07505621 A JP H07505621A
Authority
JP
Japan
Prior art keywords
group
peptide
formula
labeled
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5516829A
Other languages
English (en)
Japanese (ja)
Inventor
エンシング、ゲールト・ヤーコプ
パーネク、カーレル・ヤン
ドゥーデンス、バーレルト・ヤン
Original Assignee
マリンクロッド・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マリンクロッド・インコーポレイテッド filed Critical マリンクロッド・インコーポレイテッド
Publication of JPH07505621A publication Critical patent/JPH07505621A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
JP5516829A 1992-03-25 1993-03-24 外科手術中における腫瘍組織の検出および探知法 Pending JPH07505621A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92200848 1992-03-25
EP92200848.7 1992-03-25
PCT/US1993/002772 WO1993018797A1 (en) 1992-03-25 1993-03-24 Method of intraoperatively detecting and locating tumoral tissues

Publications (1)

Publication Number Publication Date
JPH07505621A true JPH07505621A (ja) 1995-06-22

Family

ID=8210503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5516829A Pending JPH07505621A (ja) 1992-03-25 1993-03-24 外科手術中における腫瘍組織の検出および探知法

Country Status (5)

Country Link
EP (1) EP0636032A1 (zh)
JP (1) JPH07505621A (zh)
AU (1) AU3967593A (zh)
CA (1) CA2131315A1 (zh)
WO (1) WO1993018797A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11514329A (ja) * 1994-02-18 1999-12-07 マリンクロット・メディカル・インコーポレイテッド 標識化ペプチド化合物
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AUPO066096A0 (en) * 1996-06-26 1996-07-18 Peptide Delivery Systems Pty Ltd Oral delivery of peptides
JP2001511152A (ja) * 1997-02-03 2001-08-07 マリンクロッド・インコーポレイテッド 悪性ヒト腫瘍の検出および位置特定法
CA2341489A1 (en) * 1998-09-25 2000-04-06 Mallinckrodt, Inc. Somatostatin receptor radioligand with increased uptake
US6331703B1 (en) 1999-03-12 2001-12-18 Ethicon Endo-Surgery, Inc. Guidance method for radiation detection
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
ES2383752T3 (es) 2003-05-15 2012-06-26 Trustees Of Tufts College Analogos estables de GLP-1
CN100475271C (zh) 2003-08-20 2009-04-08 加利福尼亚大学董事会 具有抑制生长激素释放活性的促生长素抑制素类似物
KR20080052649A (ko) 2005-09-08 2008-06-11 트러스티즈 오브 터프츠 칼리지 안정화된 ｇｌｐ―1 유사체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
HU219336B (en) * 1989-07-20 2001-03-28 Novartis Ag Process for producing peptide derivatives and pharmaceutical compositions comprising such compounds and diagnostic unit containing such compounds

Also Published As

Publication number Publication date
EP0636032A1 (en) 1995-02-01
WO1993018797A1 (en) 1993-09-30
AU3967593A (en) 1993-10-21
CA2131315A1 (en) 1993-09-30

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