JPH07500586A - 新規２，６−ジ置換プリン誘導体 - Google Patents

新規２，６−ジ置換プリン誘導体

Info

Publication number
JPH07500586A
JPH07500586A JP5507362A JP50736293A JPH07500586A JP H07500586 A JPH07500586 A JP H07500586A JP 5507362 A JP5507362 A JP 5507362A JP 50736293 A JP50736293 A JP 50736293A JP H07500586 A JPH07500586 A JP H07500586A
Authority
JP
Japan
Prior art keywords
formula
compound
tables
defined above
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5507362A
Other languages
English (en)
Japanese (ja)
Inventor
クヌットセン，ラース　ヤコブ　ストライ
ラウ，イェスペル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of JPH07500586A publication Critical patent/JPH07500586A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP5507362A 1991-10-24 1992-10-21 新規２，６−ジ置換プリン誘導体 Pending JPH07500586A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK9100324 1991-10-24
DK91/00324 1991-10-24
PCT/DK1992/000307 WO1993008206A1 (en) 1991-10-24 1992-10-21 Novel 2,6-disubstituted purine derivatives

Publications (1)

Publication Number Publication Date
JPH07500586A true JPH07500586A (ja) 1995-01-19

Family

ID=8153695

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5507362A Pending JPH07500586A (ja) 1991-10-24 1992-10-21 新規２，６−ジ置換プリン誘導体

Country Status (11)

Country Link
US (2) US5432164A (enExample)
EP (1) EP0609375A1 (enExample)
JP (1) JPH07500586A (enExample)
AU (1) AU657374B2 (enExample)
CA (1) CA2121844A1 (enExample)
FI (1) FI941876L (enExample)
IL (1) IL103513A (enExample)
NO (1) NO300461B1 (enExample)
NZ (1) NZ244875A (enExample)
WO (1) WO1993008206A1 (enExample)
ZA (1) ZA928222B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516641A (ja) * 2003-02-03 2006-07-06 シーブイ・セラピューティクス・インコーポレイテッド アデノシン受容体の完全アゴニストおよび部分アゴニスト

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432164A (en) * 1991-10-24 1995-07-11 Novo Nordisk A/S C2,N6 -disubstituted adenosine derivatives
US5589467A (en) * 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
EP0704215A3 (en) * 1994-06-02 1998-04-01 Takeda Chemical Industries, Ltd. Inhibitor of vascular permeability enhancer
AU2022497A (en) * 1996-03-13 1997-10-01 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
WO1997033591A1 (en) * 1996-03-13 1997-09-18 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
RU2172320C2 (ru) * 1996-08-27 2001-08-20 Си Ви Терапьютикс, Инк. Производные аденозина, фармацевтическая композиция и способ коррекции электрических нарушений в сердце млекопитающего
US5789416B1 (en) * 1996-08-27 1999-10-05 Cv Therapeutics Inc N6 mono heterocyclic substituted adenosine derivatives
AU4377397A (en) * 1996-10-14 1998-05-11 Novo Nordisk A/S Novel therapeutically active adenosine derivatives
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
US6175004B1 (en) * 1998-09-01 2001-01-16 Isis Pharmaceuticals, Inc. Process for the synthesis of oligonucleotides incorporating 2-aminoadenosine
US6576619B2 (en) 1999-05-24 2003-06-10 Cv Therapeutics, Inc. Orally active A1 adenosine receptor agonists
US6294522B1 (en) * 1999-12-03 2001-09-25 Cv Therapeutics, Inc. N6 heterocyclic 8-modified adenosine derivatives
US7342003B2 (en) * 2001-10-25 2008-03-11 King Pharmaceuticals Research And Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
WO2005033121A2 (en) * 2003-10-03 2005-04-14 King Pharmaceuticals Research & Development, Inc. Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs
WO2007107598A1 (en) 2006-03-21 2007-09-27 Heinrich-Heine-Universität Düsseldorf Phosphorylated a2a receptor agonists
EP3082731B1 (en) 2013-12-19 2018-07-04 The Procter and Gamble Company Shaping keratin fibres using an active agent comprising at least two functional groups selected from: -c(oh)- and -c(=o)oh
WO2016100258A1 (en) 2014-12-19 2016-06-23 The Procter & Gamble Company Method of shaping keratin fibres
CN107106472A (zh) 2014-12-19 2017-08-29 宝洁公司 利用阿拉伯糖和碳酸亚乙酯使角蛋白纤维成形
AR131380A1 (es) 2022-12-16 2025-03-12 Astrazeneca Ab Purinas 2,6,9-trisustituidas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE768925A (fr) * 1970-06-30 1971-11-03 Takeda Chemical Industries Ltd Derives d'adenosine et procede de preparation
JPH0696534B2 (ja) * 1986-04-25 1994-11-30 ヘキストジヤパン株式会社 抗痴呆剤
US5017578A (en) * 1989-06-09 1991-05-21 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents
EP0423777A3 (en) * 1989-10-19 1991-09-25 G.D. Searle & Co. Method of treating gastrointestinal motility disorders
US5432164A (en) * 1991-10-24 1995-07-11 Novo Nordisk A/S C2,N6 -disubstituted adenosine derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006516641A (ja) * 2003-02-03 2006-07-06 シーブイ・セラピューティクス・インコーポレイテッド アデノシン受容体の完全アゴニストおよび部分アゴニスト

Also Published As

Publication number Publication date
ZA928222B (en) 1994-04-25
FI941876A0 (fi) 1994-04-22
US5578582A (en) 1996-11-26
WO1993008206A1 (en) 1993-04-29
NO941477D0 (no) 1994-04-22
AU657374B2 (en) 1995-03-09
CA2121844A1 (en) 1993-04-29
FI941876A7 (fi) 1994-06-22
FI941876L (fi) 1994-06-22
AU2916092A (en) 1993-05-21
NO300461B1 (no) 1997-06-02
NO941477L (enExample) 1994-06-23
IL103513A0 (en) 1993-03-15
EP0609375A1 (en) 1994-08-10
US5432164A (en) 1995-07-11
IL103513A (en) 1996-09-12
NZ244875A (en) 1995-04-27

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