JPH07216731A - Antimicrobial processing liquid comprising galenical extract and mixed solution thereof - Google Patents

Abstract

PURPOSE:To obtain an antimicrobial processing liquid which is a solution, comprising galenical extracts having antimicrobial activities against Propionibacterium acnes, etc., indigenous to the skin and capable of imparting antimicrobial properties to fibers after washing and its mixture solution. CONSTITUTION:This antimicrobial processing liquid is a solution of a simple substance comprising hot water extracted essences of various galenicals having antiviral and antimicrobial actions or essences extracted from the galenicals of the same kinds with an alcohol or a complex solution comprising both the extracted essences. The processing liquid is capable of imparting antimicrobial properties to fibers. This antimicrobial processing mixed solution is a mixed solution prepared by adding a fiber softening agent, etc., of propylene glycol and a nonionic and a cationic surfactants to the antimicrobial processing liquid comprising the extracted essences of the galenicals and capable of imparting the antimicrobial properties to the fibers.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an antibacterial processing liquid for imparting antibacterial properties to fibers and a mixed liquid thereof.

[0002]

2. Description of the Related Art As the aging society advances, more and more people are suffering from symptoms such as so-called incontinence and pee leakage, and more sick people are suffering from bed sores. As those isolated from bedsore skin tissue, morphotrophic bacteria, Pseudomonas aeruginosa, and anaerobic fungi are known. Many anaerobic bacteria are the source of body odor, and bacterial infections are treated with antibiotics such as gentamicin and teramycin. Has been done.

As a means for preventing the generation of body odor due to incontinence or bed sores, it is possible to prevent it to some extent by frequently replacing shirts and pants that directly contact the body of a sick person, or underwear such as pajamas and sleepwear, but it is also possible to replace underwear. Takes a lot of time,
In recent years, underwear that has been woven with conductive fibers that are considered to have a bactericidal effect and has undergone far-infrared processing has been used. (For example, Japanese Laid-Open Patent Publication No. 2-154071 and Japanese Utility Model Laid-Open No. 56-134.
(Publication No. 390)

[0004]

[Problems to be Solved by the Invention] In the treatment with antibiotics such as gentamicin and teramycin, continuous use of this kind of antibiotics may exacerbate the illness, and it may be difficult to treat with other therapeutic agents. In some cases, it may not be possible to use it. For underwear with far-infrared processing or conductive fiber woven, processing is troublesome and expensive,
In addition, there was a problem that it had a bad feel to the skin and the effect was extremely reduced each time it was washed.

The most serious problem in incontinence is the generation of odor due to the production of propionic acid and butyric acid due to the decomposition of secretions by enzymes possessed by certain bacteria. It was also clarified that the generation of odor due to bed sores is caused by the presence of certain fungi, as is the body odor peculiar to the elderly. Therefore, the present invention has been made in order to improve the conventional problems, the object of the present invention is a solution composed of a crude drug extract having antibacterial activity against acne bacteria etc. resident in the skin. An object of the present invention is to provide an antibacterial processing liquid that imparts antibacterial properties to fibers, and an antibacterial processing liquid mixture containing the antibacterial processing liquid.

[0006]

In order to achieve the above object, the antibacterial processing liquid of the present invention is an antivirus, and a hot water extract of various crude drugs having an antibacterial action or an alcohol extract of the same crude drug. A solution or a composite solution of both extracts, which imparts antibacterial properties to fibers,
The antibacterial processed liquid of the present invention is the antibacterial processed liquid of the above invention,
It is a mixed solution containing propylene glycol and a fiber softening agent such as a nonionic or cationic surfactant, and imparts antibacterial properties to the fibers.

[0007]

[Action] Crude herbs that are believed to have anti-virus and antibacterial properties, such as Ougon (yellow rice), Owabaku (yellow oak), Ouren (yellow lichen), Koboku (koboku), Reishi (reishi), Asenyak (Asenyaku) ) Was extracted with hot water extract and berberine sulfate as a comparative sample, and Proponibacterium ac
nes) 1 × 100,000 cells / ml and cultured in a liquid medium under anaerobic conditions at 37 ° C. for 48 hours, and the results shown in Table 1 were obtained.

[0008]

[Table 1]

[0009]

EXAMPLES First, an antibacterial processing liquid using the crude drug extract of the present invention will be described. Antivirus and crude drug having antibacterial action are extracted with hot water to obtain an antibacterial processed liquid consisting of hot water extract, while the same crude drug is heated and extracted with alcohol to obtain an antibacterial processed liquid consisting of alcohol extract. As a crude drug having antivirus and antibacterial action, a crude drug having a strong antibacterial action against at least acne bacteria resident in the skin,
For example, Koboku and Oren are used.

Experimental Example 1 1 g of 40% alcohol was added to each 50 g of Reishi and Kobuku herbal medicine, and the mixture was placed in an extractor equipped with a reflux condenser and heated to about 75 ° C. for 10 hours for extraction. The extract is filtered, and the extract after filtration is concentrated under reduced pressure to 500 ml to obtain an antibacterial processing liquid of the present invention consisting of an alcohol extract.

Experimental Example 2 1 g of deionized water for each 50 g of Reishi and herb medicine
Add liter, put in an extractor equipped with a reflux condenser, heat to about 90 ° C. and extract for 10 hours. The extract is filtered, and the filtered extract is concentrated under reduced pressure to 500 ml to obtain the antibacterial processed liquid of the present invention comprising a hot water extract.

The alcohol extract of crude drug obtained in Experimental Example 1 and the hot water extract of crude drug obtained in Experimental Example 2 were combined at a ratio of, for example, 2: 8 to 8: 2. It is also possible to obtain an antibacterial processing liquid of the present invention.

Next, the antibacterial processing mixed solution of the crude drug extract of the present invention will be explained based on examples. At least a softening agent for softening the fibers is mixed with the antibacterial processing liquid containing the hot water extract of the invention or the antibacterial processing liquid containing the alcohol extract, and the solution is used to obtain the antibacterial processing liquid mixture of the present invention. The composite solution of the hot water extract and the alcohol extract is mixed with at least a softening agent for softening the fibers to obtain the antibacterial processed liquid mixture of the present invention.

As a softening agent to be added to the antibacterial processing liquid or the antibacterial processing mixture, stearyl alcohol (cetanol), propylene glycol and nonionic and cationic surfactants, which soften the fibers and are gentle on the skin, Or use several types. For example, 12g of each surfactant
Add each one to dissolve and make up to a total volume of 1 liter with deionized water.

Experimental Example 3 500 ml of deionized water was added to 5 g of Ganoderma lucidum extract (65 g of the amount equivalent to the original drug) and dissolved by stirring. To this, 12 g each of nonionic and cationic surfactants as a softening agent were added and dissolved, and 10 g of magnolia bark extract (50 g of the crude drug equivalent) was added to 40 g.
What is dissolved in 50 ml of% alcohol is added, and a total volume of 1 liter of antibacterial processed mixture is prepared with deionized water.

The effect of the antibacterial processed mixture of the present invention obtained in Experimental Example 3 on the growth of Acne bacteria was examined under the test conditions of 1 × 1000 cells / ml of Acne bacteria at 37 ° C. under anaerobic conditions in a liquid medium for 48 hours. Upon investigation, the results were obtained as shown in Table 2.

[0017]

[Table 2]

Further, acne bacteria 1 × 1000 cells / ml
Was cultured in 1.5% agar medium at 37 ° C. for 48 hours under anaerobic conditions, and the diameter of the inhibition circle (sample amount: 50 μl / disc) of the antibacterial processed mixture of the present invention obtained in Experimental Example 3 was investigated. Place 3
The result was obtained as follows.

[0019]

[Table 3]

The antibacterial processing liquid or the antibacterial processing liquid mixture of the present invention dissolves 40 ml in 1 liter of water at the time of washing and finishing, and about 5 sheets for adult underwear and about 10 sheets for diapers. After soaking, squeeze normally to dehydrate and dry as before. Although the amount of the antibacterial processing liquid or the antibacterial processing liquid mixture dissolved in 1 liter of water at the time of washing and finishing may be slightly changed depending on the amount of the laundry washed, it is preferable to dissolve 20 to 50 ml. Fibers (mainly underwear and pants) dipped in the antibacterial processing liquid or the antibacterial processing mixture may be dyed with the pigment of the herbal medicine component.

The antibacterial processing liquid and the antibacterial processing liquid mixture of the present invention are not limited to the above examples. For example, if the efficiency in extracting an extract from various crude drugs is neglected, it is 1 to 99.
% Alcohol can be used or extraction can be performed at room temperature, but it is economically preferable to use 20 to 50% alcohol and to heat at 50 to 80 ° C. for 3 to 8 hours. It is also possible to add natural dyes such as Benihana, shiso, persimmon astringent, or synthetic dyes to the antibacterial processed liquid, and the amount of the antibacterial processed liquid and the antibacterial processed liquid used is the amount of underwear to be antibacterial processed. Can be changed as appropriate.

[0022]

Since the antibacterial processing liquid and the antibacterial processing mixed liquid according to the present invention are as described above, the following effects can be obtained. As can be seen from the examples, it can be demonstrated that it has a strong antibacterial activity against acne bacteria resident on the skin. By immersing the washed fibers (underwear) in the antibacterial processing liquid of the present invention and drying in the sun, it was possible to suppress the generation of offensive odor and body odor peculiar to the elderly. It was also effective in preventing bed sores.

Claims (4)

[Claims] 1. An antibacterial processing liquid for imparting antibacterial properties to fibers, which is a solution comprising an antivirus and a hot water extract of various crude drugs having an antibacterial action. 2. An antibacterial processing liquid for imparting antibacterial properties to fibers, which is a solution comprising an anti-virus and an alcohol extract of various crude drugs having an antibacterial effect. 3. An antibacterial processing liquid which imparts antibacterial properties to fibers with a solution comprising a hot water extract of various crude drugs having antivirus and an antibacterial action and an alcohol extract of similar crude drugs. 4. An antibacterial processing liquid mixture in which at least a fiber softener is mixed with the antibacterial processing liquid of the present invention consisting of an extract of a crude drug.