JPH07145033A - Cosmetic for prevention of dermal aging - Google Patents

Abstract

PURPOSE:To prepare a cosmetic having an excellent and stable effect on prevention of dermal aging and excellent in improving effect on rough skin and skin- whitening effect. CONSTITUTION:This cosmetic for prevention of dermal aging contains perilla oil and one or more kinds of components selected from Japanese green gentian extract, camphor, nicotinic acid or its derivative, garlic extract, cepharanthine and red pepper tincture.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition, and more particularly to a cosmetic composition for preventing skin aging, which has excellent effects of preventing skin aging, rough skin, and the like.

[0002]

2. Description of the Related Art Conventionally, medicinal ingredients that have been used to improve skin roughness and prevent skin aging include allantoin, aloe extract, ginseng extract, placental extract, bovine blood deproteinate and fermented metabolites. Are known. However, cosmetics containing these medicinal components cannot obtain sufficient effects, and development of cosmetics having more excellent action has been desired.

On the other hand, perilla oil contains a large amount of α-linolenic acid which is a kind of ω-3 polyunsaturated fatty acid, and when applied to the skin, moisturizes and prevents the skin from becoming bulky. Are known. Also, this α-linolenic acid is
It is metabolized in the body to eicosapentaenoic acid and docosahexaenoic acid. These ω-3 polyunsaturated fatty acids are currently attracting attention because they are known to have an anti-cancer effect and an effect of reducing the production of leukotrienes that cause allergic reactions.

[0004]

DISCLOSURE OF THE INVENTION The present inventors have focused on the above-mentioned action of sesame oil and attempted to add it to a cosmetic, particularly a cosmetic having a rough skin improving action. However, when the sesame oil is blended alone, the rough skin improving effect cannot be said to be sufficient, and due to the influence of other bases etc., the actual effect of this cannot be sufficiently exerted. It was

Further, there is a limit to the action and effect when the perilla oil is blended at a high concentration for the purpose of obtaining a higher effect.
On the contrary, there is also a problem that due to the generation of the unique color and odor of these compounds themselves, there are restrictions on the amount of formulation, formulation, etc. in terms of products.

[0006]

In view of the above circumstances, the inventors of the present invention have conducted earnest studies to sufficiently bring out the action of perilla oil. And as a result, by combining these with a specific compound, excellent skin aging prevention effect,
The present invention has been completed by finding that the rough skin improving effect is stably and synergistically exhibited.

That is, the present invention relates to perilla oil, assemblage extract, camphor, nicotinic acid or its derivative,
A cosmetic for preventing skin aging, which comprises one or more components selected from garlic extract, cepharanthin and capsicum tincture.

The perilla oil is isolated and purified from the fruits of perilla belonging to the Lamiaceae family by a commonly used method, and the method is not particularly limited. Also, the main component α
-Included are those in which linolenic acid is further concentrated to increase its content, or oil and fat compositions prepared by mixing these other components.

The perilla oil may be blended with the cosmetic of the present invention as it is, or may be refined by steam distillation, activated carbon treatment, acid clay treatment, or the like.

The content of perilla oil in the cosmetic of the present invention is 0.0001 to 10% by weight (hereinafter simply referred to as "%"), and more preferably 0.01 to 5%.
If the content is less than 0.0001%, a sufficient effect may not be obtained, and even if the content exceeds 10%, no further increase in the effect is observed, and instead, coloring and odor are generated. Also, depending on the dosage form, problems such as precipitation may occur on the product side.

On the other hand, in the present invention, other essential components such as assembly extract, camphor, nicotinic acid or its derivative, garlic extract, cepharanthin and capsicum tincture (hereinafter collectively referred to as "second component").
Are all components that have been conventionally blended in cosmetics. Among these second components, the assembly extract, camphor, garlic extract, cepharanthin and capsicum tincture are substances obtained by extraction from natural products.

[0012] That is, the assembly extract is a product of [Sertieria japonica Makino (G
[entia neceae)] is an extract obtained by extracting with ethanol, purified water, or a mixed solution thereof from whole plants in the flowering period, and camphor is camphor [Cinnam
om camphora linne (Laura
ceae)] is a terpene ketone.

The garlic extract is garlic (Al
ium scodoplasm L. Or Alli
um sativum L. ) Is an extract obtained by extracting the bulb from purified water, absolute ethanol, propylene glycol, 1,3-butylene glycol or a mixture thereof.

[0014] Further, cepharanthin is a plant belonging to the family Amaranthaceae, Tamasaki tsutsurafuji (Stephaura cep).
Harantha Hayata). Furthermore, capsicum tincture is a capsicum [Capsicum annuum Linn
e (Solanaceae)] or a variety thereof, which is a tincture obtained by leaching with ethanol. In addition,
In either case, there are no particular restrictions on the extraction method and the purification treatment method.

On the other hand, nicotinic acid and its derivatives are a kind of vitamin B, and may be those obtained by extraction from beef liver, rice bran or the like, or those obtained by synthesis,
In addition to nicotinic acid, nicotinic acid amide, nicotinic acid DL-
Examples include nicotinic acid derivatives such as α-tocopherol and methyl nicotinate.

The content of these second components in the cosmetic of the present invention is generally 0.0001 to 5%, preferably 0.001.
1 to 3%. The content of these components is 0.0001%
If it is less than the above range, a sufficient effect may not be obtained, and even if the content exceeds 5%, the effect becomes almost constant, and the increase is not observed.

Further, in the cosmetic of the present invention, in addition to the above-mentioned essential components, an aqueous component, a powder, a surfactant, an oil agent, a moisturizing agent used in ordinary cosmetics, in the range not impairing the effects of the present invention. Agents, alcohols, pH adjusters, antiseptics, pigments, antioxidants, ultraviolet absorbers, thickeners, fragrances, cosmetic ingredients and the like can be appropriately added as necessary.

The skin anti-aging cosmetic composition of the present invention contains the above-mentioned sesame oil which is an essential component, the assembly extract, camphor,
Nicotinic acid or a derivative thereof, garlic extract, cepharanthine and one or more components selected from capsicum tincture can be blended and produced according to a conventional method, emulsion, cream, lotion, beauty essence, cleansing, pack. It can be applied as a cleaning agent, foundation, etc.

[0019]

EXAMPLES Next, the present invention will be described in more detail by way of examples, which should not be construed as limiting the invention thereto.

Examples 1 to 4 Creams Creams having the compositions shown in Table 1 below were produced, and the effect of improving rough skin was examined. The results are also shown in Table 1. The cream production method and evaluation method are as follows.

[0021]

[Table 1]

(Production Method) A. The components (8) and (10) to (14) are heated and mixed, and
Keep at 0 ° C. B. The components (1) to (7) and (9) are heated and mixed to obtain 70
Keep at ℃. C. The above B is added to the above A, mixed and uniformly emulsified. D. After cooling the above C, (15) was added and uniformly mixed to obtain a cream.

(Evaluation method) 135 healthy men were used as a panel, and 15 people per group, the creams of Examples 1 to 4 or Comparative Examples 1 to 5 were applied to one half of the face, and the cream of Comparative Example 6 was applied to the other face. , Once a day for 2 weeks. Two weeks later, a facial skin replica was collected and evaluated according to the criteria shown below. The value obtained by subtracting the score of the replica of the cream applied site of Comparative Example 6 from the obtained score of the replica of the cream applied site of Examples 1 to 4 and Comparative Examples 1 to 5 was taken as the degree of improvement in skin roughness. In addition, the score before the start of the test is 1 on the panel
Or I chose 2 men.

Skin condition score: Score condition 1 The skin groove of the skin is unclear and peeling of the keratin is observed. 2 The skin groove on the skin is slightly blurred or unidirectional. 3 Skin groove is observed, but it is shallow or slightly unidirectional. 4 Skin crevices are observed or are slightly mesh-like. 5 Skin groove is clearly visible or has a clean mesh.

From the above results, it is clear that the cosmetic of the present invention in which the sesame oil and the second component are blended has a remarkable effect of improving rough skin as compared with the case where the sesame oil or the second component is blended alone. Is.

Examples 5 to 6 Cream Creams were prepared according to the composition shown in Table 2 and the following production method, and their anti-aging effect on skin was examined by the following method.

[0027]

[Table 2]

(Production Method) A. The components (9) to (11) and (13) are heated and mixed,
Keep at 70 ° C. B. The components (1) to (8) are mixed by heating and kept at 70 ° C. C. The above B is added to the above A, mixed and uniformly emulsified. D. After cooling the above C, the component (12) was added and uniformly mixed to obtain a cream.

(Evaluation Method) Fifteen women aged 26 to 52 were used as a panel, and an appropriate amount of the test cream was applied to the face after washing the face twice a day every morning and night for 12 weeks. The effect of applying beautiful skin and the effect of preventing skin aging were evaluated according to the following criteria.

Skin-Beauty Effect: Evaluation Content Effective Dullness of the skin became inconspicuous. Somewhat effective The dullness of the skin has become a little less noticeable. Disabled No change from before use.

Skin Aging Preventive Effect: Evaluation Content Effective The skin's suppleness and gloss were improved. Slightly effective Skin tone and gloss were slightly improved. Disabled No change from before use.

(Results) The results are shown in Table 3.

[0033]

[Table 3]

As is clear from the results shown in Table 3, the creams of Examples 5 and 6 are effective in preventing and improving the loss of "gloss", "beams" and "dullness" of the skin, and aging of the skin. The preventive effect was recognized.

Example 7 Lotion (Formulation) (wt%) (1) Polyoxyethylene hydrogenated castor oil (60 EO) 1.0 (2) Ethyl alcohol 10.0 (3) Preservative 0.1 ( 4) Perfume proper amount (5) Perilla oil 1.0 (6) Assemblage extract 0.5 (7) Sorbitol (70% aqueous solution) 3.0 (8) Sodium pyrrolidonecarboxylate 3.0 (9) Purified water Remaining amount

(Production Method) A. The components (1) to (5) are heated and mixed to dissolve. B. The components (6) to (9) are heated and mixed to dissolve. C. The above A and B were mixed and made uniform to obtain a lotion.

Example 8 Emulsion (formulation) (wt%) (1) Polyoxyethylene sorbitan monostearate 1.0 (10 EO) (2) Polyoxyethylene sorbit tetraoleate 0.5 (60 EO) (3) Glycerin monostearate 1.0 (4) Stearic acid 0.5 (5) Behenyl alcohol 0.5 (6) Refined avocado oil 4.0 (7) Glycerin tri-2-ethylhexanoate 4.0 ( 8) Preservative 0.1 (9) Perilla oil 1.0 (10) Witch hazel extract 0.1 (11) Xanthan gum (2% aqueous solution) 7.0 (12) 1,3-butylene glycol 5.0 (13) ) Camphor 1.0 (14) Cepharanthin 1.0 (15) Purified water Remaining amount (16) Perfume proper amount

(Production Method) A. The components (10) to (15) are mixed by heating and kept at 70 ° C. B. The components (1) to (9) are mixed by heating and kept at 70 ° C. C. The above B is added to the above A, mixed and uniformly emulsified. D. After cooling the above C, (16) was added and uniformly mixed to obtain an emulsion.

Example 9 Ointment (formulation) (% by weight) (1) Stearic acid 18.0 (2) Cetanol 4.0 (3) Triethanolamine 2.0 (4) Glycerin 5.0 (5) Perilla oil 2.0 (6) Garlic extract 1.0 (7) Purified water Remaining amount

(Production Method) A. A part of the components (3) to (4) and (7) is mixed by heating and kept at 75 ° C. B. The components (1) to (2) and (5) are heated and mixed, and 75
Keep at ℃. C. Gradually add A above to B above. D. While cooling the above C, (6) dissolved in the rest of (7) was added to obtain an ointment.

[0041]

INDUSTRIAL APPLICABILITY As described in detail above, according to the present invention, a cosmetic having a stable and excellent effect of preventing skin aging and improving rough skin can be obtained.

Claims (1)

[Claims] 1. Sesame oil, assemblage extract, camphor, nicotinic acid or its derivative, garlic extract,
A cosmetic for preventing skin aging containing one or more components selected from cepharanthin and capsicum tincture.